Translational Neuroimmunology

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• Author : Sandra Amor,Fabienne Brilot,David Brown,Judith M. Greer,Marc J. Ruitenberg
• Publisher : Frontiers Media SA
• Release Date : 2020-12-29
• Total pages : 253
• ISBN : 9782889662951
• File Size : 26,7 Mb
• Total Download : 230
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Download Update on Translational Neuroimmunology - Research of ISNI 2018 in PDF, Epub, and Kindle

The 14th International Congress of Neuroimmunology, ISNI 2018, was held in August 2018 in Brisbane, Australia, and is a biennial event organized by the International Society of Neuroimmunology (ISNI). The theme of ISNI 2018 was “Travelling the Neuroimmunological Translational Highway”, and the Congress highlighted many research discoveries that bridge the gap between basic and clinical sciences, and which impact our understanding of pathogenic immune-mediated mechanisms in diseases affecting the nervous system. In this Research Topic, we aim to give a comprehensive overview of topics highlighted at the Congress, showcasing the current state of the field of neuroimmunology and where it is going in the near future.

• Author : Ruth Arnon,Ariel Miller
• Publisher : Academic Press
• Release Date : 2016-05-10
• Total pages : 504
• ISBN : 9780128020074
• File Size : 54,8 Mb
• Total Download : 298
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Download Translational Neuroimmunology in Multiple Sclerosis in PDF, Epub, and Kindle

Multiple sclerosis (MS) is the most common disabling neurological disease of young adults. More than 2.3 million people are affected by MS worldwide. Symptoms can vary widely, depending on the localization and amount of the damage induced by combined inflammatory, demyelinating, and neurodegenerative processes. Although a cure for MS does not currently exist, therapies can help treat MS attacks, attenuate disease activity, reduce progress of the disease, and manage symptoms. Translational Neuroimmunology in Multiple Sclerosis provides an overview of recent findings and knowledge of the neuroimmunology of multiple sclerosis, from experimental models and the human disease to the translation of this research to immunotherapeutic strategies. Chapters describe genetic and environmental factors underlying the disease pathogenesis of MS as a basis for development of immunotherapies, immunological markers of disease activity, pharmacogenetics, and responses to therapy. Immunomodulatory therapies currently in practice and future therapeutic strategies on the horizon—such as neuroprotective strategies, stem cells, and repair promotion—are discussed. Contributed by renowned leaders in the field, this cross-disciplinary volume is a great resource for basic scientists and clinical practitioners in neuroscience, neurology, immunology, pharmacology, and in-drug development. Provides an overview of recent findings and knowledge of the neuroimmunology of multiple sclerosis and the translation of this research to immunotherapy treatment Edited by renowned leaders in the field of neuroimmunology and multiple sclerosis Contains the latest resource material for basic and clinical scientists and practitioners in neuroscience, neurology, immunology, and pharmacology

• Author : Nima Rezaei
• Publisher : Academic Press
• Release Date : 2023-03-01
• Total pages : 0
• ISBN : 0323858414
• File Size : 42,8 Mb
• Total Download : 231
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Download Translational Neuroimmunology in PDF, Epub, and Kindle

Neuroimmunology is a growing field, which combines the knowledge of the immune system and the nervous system. "Translational NeuroImmunology" addresses an update on bench to bedside studies on neurological disorders that have immunological aetiologies. Although neural-immune dysregulation and all autoimmune and autoinflammatory neurologic disorders will be discussed in this new volume of "Translational Immunology" Book Series. Divided into 22 chapters, the book begins with an in-depth introduction to neuroimmunology and the principles of autoimmune and autoinflammatory neurological disorders. Multiple sclerosis will be the main focus. The immunopathology, genetics and epigenetics, microbiome, diagnosis and treatment of multiple sclerosis will be explained in "Translational NeuroImmunology". 10 chapters are devoted to multiple sclerosis. The immunopathology, genetics and epigenetics, microbiome, diagnosis and treatment of multiple sclerosis will be explained. Following this, one chapter that examines distinct aspects of pericytes. Finally, the book closes with a review on the neurologic manifestations, diagnostic approaches and treatments of the various neuroimmune disorders and lessons learned from non-human primates and zebrafish translational research. All are presented in an accessible, practical format, making this volume a valuable resource for immunologists, neurologists and researchers in translational biomedical research.

• Author : Anonim
• Publisher : Academic Press
• Release Date : 2018-11-24
• Total pages : 294
• ISBN : 9780128138335
• File Size : 32,9 Mb
• Total Download : 638
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Download Translational Inflammation in PDF, Epub, and Kindle

Translational Inflammation links laboratory and clinical data within primary and secondary care to clinical research data and offers a holistic and innovative approach to chronic inflammation and ageing. Understanding the role of inflammation as a part of clinical disease states is becoming a valuable tool in both direct treatment and the development of therapeutics. Translational Inflammation, the 4th volume in the Perspectives in Translational Cell Biology series, offers content for professors, students and researchers across basic and translational biology. Emphasizes the role of inflammation in disease and therapeutic approaches Integrates broad concepts relating inflammation to other fields Offers a bridge to review literature and primary research on the inflammatory response towards medical application

• Author : Nima Rezaei,Niloufar Yazdanpanah
• Publisher : Elsevier
• Release Date : 2023-03-23
• Total pages : 0
• ISBN : 9780443185793
• File Size : 17,6 Mb
• Total Download : 984
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Download Translational Neuroimmunology, Volume 8 in PDF, Epub, and Kindle

Translational Neuroimmunology: Multiple Sclerosis provides an update on bench to bedside studies on Multiple Sclerosis as an autoimmune disease. Divided into twelve chapters, the book begins with an in-depth introduction to the neuroimmunology and immunopathology of multiple sclerosis. Sections also provide content on genetics and epigenetics, the microbiome, diagnosis, and treatment of multiple sclerosis. Finally, various precision treatments are covered. All information is presented in an accessible, practical format, making this volume a valuable resource for immunologists, neurologists and researchers in translational biomedical research. Provides an introduction on multiple sclerosis as an autoimmune disease, from bench to bedside Encourages the development of immunologic approaches to analyze the interaction and specific properties of nervous tissue elements during development and disease Focuses on understanding and therapeutically manipulating immunological responses to injury, degeneration and autoimmunity in the central nervous system Shows the changes in relevant immune and inflammatory reactions at the cellular and molecular level during the development of nervous system diseases

• Author : P. Michael Conn
• Publisher : Academic Press
• Release Date : 2016-09-28
• Total pages : 776
• ISBN : 9780128025963
• File Size : 47,5 Mb
• Total Download : 364
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Download Conn's Translational Neuroscience in PDF, Epub, and Kindle

Conn’s Translational Neuroscience provides a comprehensive overview reflecting the depth and breadth of the field of translational neuroscience, with input from a distinguished panel of basic and clinical investigators. Progress has continued in understanding the brain at the molecular, anatomic, and physiological levels in the years following the 'Decade of the Brain,' with the results providing insight into the underlying basis of many neurological disease processes. This book alternates scientific and clinical chapters that explain the basic science underlying neurological processes and then relates that science to the understanding of neurological disorders and their treatment. Chapters cover disorders of the spinal cord, neuronal migration, the autonomic nervous system, the limbic system, ocular motility, and the basal ganglia, as well as demyelinating disorders, stroke, dementia and abnormalities of cognition, congenital chromosomal and genetic abnormalities, Parkinson's disease, nerve trauma, peripheral neuropathy, aphasias, sleep disorders, and myasthenia gravis. In addition to concise summaries of the most recent biochemical, physiological, anatomical, and behavioral advances, the chapters summarize current findings on neuronal gene expression and protein synthesis at the molecular level. Authoritative and comprehensive, Conn’s Translational Neuroscience provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, as well as a clear demonstration of their emerging diagnostic and therapeutic importance. Provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, while also clearly demonstrating their emerging diagnostic and therapeutic importance Features contributions from leading global basic and clinical investigators in the field Provides a great resource for researchers and practitioners interested in the basic science underlying neurological processes Relates and translates the current science to the understanding of neurological disorders and their treatment

• Author : Andrew R. Pachner
• Publisher : Springer Science & Business Media
• Release Date : 2012-02-18
• Total pages : 212
• ISBN : 9781461421870
• File Size : 45,6 Mb
• Total Download : 649
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Download A Primer of Neuroimmunological Disease in PDF, Epub, and Kindle

A Primer of Neuroimmunological Disease is a significant new resource for anyone interested in conditions such as multiple sclerosis(MS), myasthenia gravis, and neurological infections. It is a practical and balanced guide to the diagnosis and treatment of neuroimmunological disease. A Primer of Neuroimmunological Disease distinguishes itself by providing a range of features not generally included in texts on neuroimmunology. These include broad presentation of information in the form of figures and tables; strong cohesion among topics by focusing on a few prototypic neuroimmunological diseases, which serve as a foundation from which to explore other neuroimmunological diseases; a single author perspective, with references across chapters; and a focus on the overlap between neuroimmunological and neuroinfectious diseases. Neurologists, immunologists, infectious disease specialists, neuroscientists and others interested in neuroimmunological diseases such as MS will find A Primer of Neuroimmunological to be a state-of-the-art resource.

• Author : Maria de los Angeles Robinson-Agramonte
• Publisher : Springer
• Release Date : 2015-06-10
• Total pages : 218
• ISBN : 9783319163215
• File Size : 17,9 Mb
• Total Download : 711
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Download Translational Approaches to Autism Spectrum Disorder in PDF, Epub, and Kindle

This book addresses and synthesizes recent basic, translational, and clinical research with the goal of understanding the mechanisms behind autism spectrum disorder (ASD) and how they lead to altered brain function and behavior. Bringing clarity to these mechanisms will lead to more effective therapies for the various heterogeneous pathologies that comprise ASD. Currently there are few, if any, proven therapies for the majority of the disorders. Among the topic addressed are neural plasticity, neuroimmunology, neuroinflammation, neuroimaging, and appropriate animal and genetic models.

• Author : Seng-Lai Tan
• Publisher : Academic Press
• Release Date : 2015-11-18
• Total pages : 384
• ISBN : 9780128017579
• File Size : 41,8 Mb
• Total Download : 748
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Download Translational Immunology in PDF, Epub, and Kindle

Translational Immunology: Mechanisms and Pharmacologic Approaches highlights and summarizes the most important advances in human immunology, clinical translations, new tools to analyze therapeutic targets, and new pharmacological approaches for autoimmunity, inflammatory disorders, and cancer. The book is an essential resource for those seeking to understand the potential translational applications of burgeoning studies in human immunology, helping readers make sense of the existing and emerging scientific advances. The book grounds fundamental science in the translational realm, providing insights from world renowned researchers at the top of their game in their respective fields, in both industry and academic settings. Readers will gain an understanding of the rationale and mechanisms underlying current and emerging pharmacologic approaches for interventional immunology, the gaps therein, and new ideas for better and safer therapeutic approaches, and physicians will glean information about pharmacological limitations in altering disease progression and complications. This reference on the translational realization of the burgeoning findings in immunology provides a go-to reference for experienced professional clinicians, researchers, industry scientists, and those seeking more information on the field. Delivers comprehensive coverage of seminal human immunology discoveries and the resulting impact on therapeutic strategies Presents potential novel targets and approaches for clinical applications in organ specific and systemic autoimmunity, transplant rejection, cancer, and vaccine development Discusses lessons learned from successful and failed clinical trials with specific interventions, including pharmacological issues and limitations, and complications due to immunosuppression Provides information on new strategies and outstanding issues that should be addressed in future research

• Author : Mohamed Salama
• Publisher : Springer Nature
• Release Date : 2022-06-20
• Total pages : 234
• ISBN : 9789811692055
• File Size : 9,5 Mb
• Total Download : 382
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Download Nutrigenomics and the Brain in PDF, Epub, and Kindle

Dr. Mohammed Salama is Atlantic senior fellow for Equity in brain health at the Global Brain Health Institute (GBHI) and Associate professor at the Institute of Global Health and Human Ecology at the American University in Cairo (AUC). He established the first Translational Neuroscience Unit in Egypt. Mohamed’s collaborative research led to establishing the Egyptian Network for Neurodegenerative Disorders Mohamed was selected as a SOT Global Senior Scholar in 2013 and Translational/bridging awardee in 2016. He was awarded by Parkinson’s and Movement Disorders Foundation (PMDF) for his continued research in neurodegeneration. Recently, Mohamed and his colleagues succeeded in drafting the first Reference Egyptian Genome and collaborating with other colleagues to start a national cohort (A Longitudinal Study of Egyptian Health Aging [AL-SEHA]). ​

• Author : Öner Özdemir
• Publisher : BoD – Books on Demand
• Release Date : 2021-09-15
• Total pages : 198
• ISBN : 9781839693496
• File Size : 41,7 Mb
• Total Download : 418
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Download Vitamin D in PDF, Epub, and Kindle

This book examines the sometimes controversial role of vitamin D in various health problems. Divided into four sections, chapters cover such topics as vitamin D deficiency in women, newborns, and the elderly, as well as the role of vitamin D in COVID-19, autism spectrum disorder, diabetes, dental diseases, and central nervous system pathological processes.

• Author : Rajesh K. Kesharwani,Raj K. Keservani,Anil K. Sharma
• Publisher : Springer Nature
• Release Date : 2022-06-17
• Total pages : 509
• ISBN : 9789811663796
• File Size : 16,9 Mb
• Total Download : 230
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Download Immunomodulators and Human Health in PDF, Epub, and Kindle

This book focuses on a broad range of immunomodulators, including both natural and synthetic ones. It highlights their role in human health. The book discusses nanotechnology-based immunomodulators with special emphasis on different types of formulation to boost the immune system. It highlights the role of immunomodulators against different microbes. This book describes important topics such as Classification and uses of various immunomodulators; Potential role of herbs and spices on immune system; Immune booster activity of prebiotics; Recent advances of nutraceutical and functional foods in Immune health; Antioxidants and immunomodulation; Nanotechnology and immunomodulators in cancer; Immunomodulatory role for the treatment and management of tuberculosis; Immunomodulation in autoimmune disorders; Herbal immunomodulators and COVID-19; Role of Cytokines as Immunomodulators and Immunomodulatory effects of endocrine disrupting chemicals. This book covers various aspects of product innovation, development, and launching of nutritional and pharmaceutical products with reference to immunomodulators. This book is meant for researchers and students in the field of immunology and pharmaceutical sciences.

• Author : Alexander Birbrair
• Publisher : Academic Press
• Release Date : 2021-11-26
• Total pages : 324
• ISBN : 9780323856430
• File Size : 21,9 Mb
• Total Download : 336
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Download Current Progress in iPSC Disease Modeling in PDF, Epub, and Kindle

Current Progress in iPSC Disease Modeling, Volume Fourteen in the Advances in Stem Cell Biology series, is a timely and expansive collection of information and new discoveries in the field. This new volume addresses advances in research on how induced pluripotent stem cells are used for the creation of new tissues and organs. The creation of iPSC technology allowed the development of disease-specific human pluripotent stem cells. These cells allow researchers to study questions once impossible for some human diseases. This volume addresses iPSCs for vascular tissue engineering, bioprinting, derived lung organoids for pulmonary disorders, skeletal muscle engineering, human kidney organoids, and more. It is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation, and is contributed by world-renowned authors in the field. Provides an overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics Covers advances in research on how induced pluripotent stem cells are used to create new tissues/organs Contributed by world-renowned experts in the field

• Author : Tom Brody
• Publisher : Academic Press
• Release Date : 2017-12-13
• Total pages : 670
• ISBN : 9780128146484
• File Size : 43,6 Mb
• Total Download : 606
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Download FDA's Drug Review Process and the Package Label in PDF, Epub, and Kindle

FDA's Drug Review Process and the Package Label provides guidance to pharmaceutical companies for writing FDA-submissions, such as the NDA, BLA, Clinical Study Reports, and Investigator's Brochures. The book provides guidance to medical writers for drafting FDA-submissions in a way more likely to persuade FDA reviewers to grant approval of the drug. In detail, the book reproduces data on efficacy and safety from one hundred different FDA-submissions (NDAs, BLAs). The book reproduces comments and complaints from FDA reviewers regarding data that are fragmentary, ambiguous, or that detract from the drug's approvability, and the book reveals how sponsors overcame FDA's concerns and how sponsors succeeded in persuading FDA to grant approval of the drug. The book uses the most reliable and comprehensive source of information available for writing FDA-submissions, namely text and data from NDAs and BLAs, as published on FDA's website. The source material for writing this book included about 80,000 pages from FDA's Medical Reviews, FDA's Clinical Pharmacology Reviews, and FDA's Pharmacology Reviews, from one hundred different NDAs or BLAs for one hundred different drugs. Each chapter focuses on a different section of the package label, e.g., the Dosage and Administration section or the Drug Interactions section, and demonstrates how the sponsor's data supported that section of the package label. Reveals strategies for winning FDA approval and for drafting the package label Examples are from one hundred FDA-submissions (NDAs, BLAs) for one hundred different drugs, e.g., for oncology, metabolic diseases, autoimmune diseases, and neurological diseases This book uses the most reliable and comprehensive source of information available for writing FDA-submissions, namely, the data from NDAs and BLAs as published on FDA's website at the time FDA grants approval to the drug

• Author : Seyed Mostafa Kia,Hassan Mohy-ud-Din,Ahmed Abdulkadir,Cher Bass,Mohamad Habes,Jane Maryam Rondina,Chantal Tax,Hongzhi Wang,Thomas Wolfers,Saima Rathore,Madhura Ingalhalikar
• Publisher : Springer Nature
• Release Date : 2020-12-30
• Total pages : 305
• ISBN : 9783030668433
• File Size : 39,8 Mb
• Total Download : 897
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Download Machine Learning in Clinical Neuroimaging and Radiogenomics in Neuro-oncology in PDF, Epub, and Kindle

This book constitutes the refereed proceedings of the Third International Workshop on Machine Learning in Clinical Neuroimaging, MLCN 2020, and the Second International Workshop on Radiogenomics in Neuro-oncology, RNO-AI 2020, held in conjunction with MICCAI 2020, in Lima, Peru, in October 2020.* For MLCN 2020, 18 papers out of 28 submissions were accepted for publication. The accepted papers present novel contributions in both developing new machine learning methods and applications of existing methods to solve challenging problems in clinical neuroimaging. For RNO-AI 2020, all 8 submissions were accepted for publication. They focus on addressing the problems of applying machine learning to large and multi-site clinical neuroimaging datasets. The workshop aimed to bring together experts in both machine learning and clinical neuroimaging to discuss and hopefully bridge the existing challenges of applied machine learning in clinical neuroscience. *The workshops were held virtually due to the COVID-19 pandemic.

• Author : Alessandro Russo,David Paterson,Matteo Bassetti
• Publisher : Frontiers Media SA
• Release Date : 2021-09-29
• Total pages : 292
• ISBN : 9782889714063
• File Size : 23,6 Mb
• Total Download : 630
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Download Spotlight on the Relationship between Sepsis and Infection: from Mechanisms to Therapy in PDF, Epub, and Kindle

PDF book entitled Spotlight on the Relationship between Sepsis and Infection: from Mechanisms to Therapy written by Alessandro Russo,David Paterson,Matteo Bassetti and published by Frontiers Media SA which was released on 2021-09-29 with total hardcover pages 292, the book become popular and critical acclaim.

• Author : Alireza Minagar
• Publisher : Academic Press
• Release Date : 2018-07-30
• Total pages : 700
• ISBN : 9780128117248
• File Size : 9,5 Mb
• Total Download : 524
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Download Neuroinflammation in PDF, Epub, and Kindle

Neuroinflammation, Second Edition, discusses the role inflammation plays in neuro-inflammatory diseases. As research in neuroinflammation has dramatically increased in recent years, this new edition covers all of the new developments and findings since the first publication nearly a decade ago. Comprehensive coverage of topics includes chapters on multiple sclerosis, optic neuritis and Susac syndrome. New chapters cover the latest research in Epilepsy and Neuroinflammation, Pediatric MS, Pediatric Lupus and Traumatic Brain Injury, amongst other topics. Inflammation is a central mechanism in many neurological diseases, including stroke, multiple sclerosis, brain trauma and meningitis, and it contributes to the generation of pain. Researchers are now beginning to understand the impact of the immune system on different nervous system functions and diseases, ranging from damage, through tolerance, and to modulation and repair. Comprehensively reviews the latest developments in neuroinflammation and neuro-inflammatory diseases Written for researchers and clinical practitioners in clinical neuroscience, neurology and immunology Includes new chapters on Epilepsy and Neuroinflammation, Pediatric MS, Pediatric Lupus and Traumatic Brain Injury

• Author : Tobias Ruck,Marcello Moccia,Tobias Warnecke,Stefan Bittner
• Publisher : Frontiers Media SA
• Release Date : 2020-04-01
• Total pages : 340
• ISBN : 9782889636433
• File Size : 43,8 Mb
• Total Download : 682
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Download Pathophysiologic Insights from Biomarker Studies in Neurological Disorders in PDF, Epub, and Kindle

PDF book entitled Pathophysiologic Insights from Biomarker Studies in Neurological Disorders written by Tobias Ruck,Marcello Moccia,Tobias Warnecke,Stefan Bittner and published by Frontiers Media SA which was released on 2020-04-01 with total hardcover pages 340, the book become popular and critical acclaim.

• Author : Emanuele D’amico,Aurora Zanghì,Carlo Avolio,Hans-Peter Hartung
• Publisher : Frontiers Media SA
• Release Date : 2022-10-13
• Total pages : 144
• ISBN : 9782832502327
• File Size : 51,8 Mb
• Total Download : 939
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Download Immunosenescence and Multiple Sclerosis: Prognostic and Therapeutic Implications in PDF, Epub, and Kindle

PDF book entitled Immunosenescence and Multiple Sclerosis: Prognostic and Therapeutic Implications written by Emanuele D’amico,Aurora Zanghì,Carlo Avolio,Hans-Peter Hartung and published by Frontiers Media SA which was released on 2022-10-13 with total hardcover pages 144, the book become popular and critical acclaim.

• Author : Sergiu Groppa,Sven G. Meuth
• Publisher : Humana
• Release Date : 2021-08-03
• Total pages : 335
• ISBN : 1071612123
• File Size : 22,8 Mb
• Total Download : 299
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Download Translational Methods for Multiple Sclerosis Research in PDF, Epub, and Kindle

This volume explores the recent advances in the study of translational paths in central inflammation and focuses on ongoing pathophysiological processes and the transition between inflammatory stages and progressive states with neurodegeneration. Chapters cover topics such as pathophysiological hallmarks of neuroinflammation from tissue damage to reorganization; connecting studies of mouse models; and investigations of humans with multiple sclerosis. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and practical, Translational Methods for Multiple Sclerosis Research is a valuable resource for researchers who want to learn more about this chronic ad progressive disease, and pave the way for new advancements.

• Author : John Michels
• Publisher : Unknown
• Release Date : 2006
• Total pages : 229
• ISBN : MINN:31951P00972595F
• File Size : 53,7 Mb
• Total Download : 200
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Download Science in PDF, Epub, and Kindle

PDF book entitled Science written by John Michels and published by Unknown which was released on 2006 with total hardcover pages 229, the book become popular and critical acclaim.