Translational Autoimmunity Advances In Rheumatic Diseases

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Translational Autoimmunity

Translational Autoimmunity
  • Author : Nima Rezaei
  • Publisher : Elsevier
  • Release Date : 2023-02-01
  • Total pages : 0
  • ISBN : 9780323984546
  • File Size : 37,8 Mb
  • Total Download : 887
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Translational Autoimmunity: Advances in Autoimmune Rheumatic Diseases, Volume Six addresses autoimmune diseases classified under the category of rheumatic diseases. Rheumatic diseases are heterogeneous groups of disorders in which inflammation affects not only joints, but also tendons, ligaments and bones. This updated release focuses on immunopathogenesis and clinical and laboratory details of rheumatic diseases, including rheumatoid arthritis, systemic lupus erythematosus, psoriatic arthritis, osteoarthritis and Sjogren’s syndrome, and will be of interest to researchers, students and clinicians interested in autoimmune diseases, especially rheumatic diseases. From an introduction to rheumatic diseases to diagnostic laboratory tests, and from the microbiota-immunity to cell based therapies, the bench to bedside approach to rheumatic diseases is the main subject of discussion in this comprehensive resource. Gives an introduction on rheumatic diseases, from bench to bedside Describes diagnostic laboratory tests in rheumatic diseases Meets the needs of basic scientists, clinicians and translational scientists and industry partners Focuses on immunopathogenesis and clinical and laboratory details of rheumatic diseases

Translational Autoimmunity

Translational Autoimmunity
  • Author : Nima Rezaei
  • Publisher : Academic Press
  • Release Date : 2022-01-21
  • Total pages : 486
  • ISBN : 9780323859752
  • File Size : 23,5 Mb
  • Total Download : 144
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Translational Autoimmunity: Treatment of Autoimmune Diseases, Volume Two in the Translational Immunology series, focuses on advances in therapeutic modalities in autoimmune diseases. Efficacy and safety of not only the current biologic therapies, but also novel drug targets are discussed. Therapeutic targeting of B regulatory cells, T regulatory cells, as well as the immunomodulation effects of nanoparticles and organisms are also covered, along with our understanding and future challenges of prognostic significance of treatments in autoimmune diseases. Covers the clinical aspects and treatment of autoimmunite diseases Meets the needs of basic scientists, clinicians and translational scientists and industry partners Mentions each and every key concept after background is drawn Supported by a systematic appraisal of the most recent evidence Helps students at all academic levels, but is also applicable to scientists who work with autoimmunity

Recent Advances in Potential Biomarkers for Rheumatic Diseases and in Cell-based Therapies in the Management of Inflammatory Rheumatic Diseases

Recent Advances in Potential Biomarkers for Rheumatic Diseases and in Cell-based Therapies in the Management of Inflammatory Rheumatic Diseases
  • Author : Eric Toussirot,Katarzyna Bogunia-Kubik,Philippe Saas
  • Publisher : Frontiers Media SA
  • Release Date : 2022-02-18
  • Total pages : 347
  • ISBN : 9782889744268
  • File Size : 33,5 Mb
  • Total Download : 162
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PDF book entitled Recent Advances in Potential Biomarkers for Rheumatic Diseases and in Cell-based Therapies in the Management of Inflammatory Rheumatic Diseases written by Eric Toussirot,Katarzyna Bogunia-Kubik,Philippe Saas and published by Frontiers Media SA which was released on 2022-02-18 with total hardcover pages 347, the book become popular and critical acclaim.

Translational Autoimmunity

Translational Autoimmunity
  • Author : Nima Rezaei
  • Publisher : Academic Press
  • Release Date : 2022-05-01
  • Total pages : 458
  • ISBN : 9780323859769
  • File Size : 18,9 Mb
  • Total Download : 222
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As the autoimmune diseases could affect different organs, Translational Autoimmunity: Autoimmune Diseases in Different Organs addresses the spectrum of autoimmune diseases. The fourth volume of Translational Immunology Series focuses on clinical and laboratory details of autoimmune diseases which are broadly categorized into two types of organ-specific autoimmune diseases and non-organ specific autoimmune diseases (also known as systemic autoimmune diseases). Autoimmune rheumatic diseases such as systemic lupus erythematosus and rheumatoid arthritis, autoimmune rheumatic diseases such as diabetes mellitus and thyroid diseases, autoimmune neurologic diseases such as multiple sclerosis, as well as autoimmune hepatobiliary diseases, autoimmune renal diseases and autoimmune cutaneous diseases as the subject of discussion in Translational Autoimmunity: Autoimmune Diseases in Different Organs. Comprises major parts that cover basic immunology, clinical aspects of autoimmunity, and translational immunology studies in autoimmunity Each and every key concept will be mentioned after an easy background is drawn and then, will be supported by a systematic appraisal of the most recent evidence Can help students at all the academic levels while applicable to scientists who work with autoimmunity Designed for learning, teaching, review and testing, practice, and research. Hence, it might be useful for students, teachers and instructors, physicians, and researchers

Translational Inflammation

Translational Inflammation
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2018-11-24
  • Total pages : 294
  • ISBN : 9780128138335
  • File Size : 35,7 Mb
  • Total Download : 565
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Translational Inflammation links laboratory and clinical data within primary and secondary care to clinical research data and offers a holistic and innovative approach to chronic inflammation and ageing. Understanding the role of inflammation as a part of clinical disease states is becoming a valuable tool in both direct treatment and the development of therapeutics. Translational Inflammation, the 4th volume in the Perspectives in Translational Cell Biology series, offers content for professors, students and researchers across basic and translational biology. Emphasizes the role of inflammation in disease and therapeutic approaches Integrates broad concepts relating inflammation to other fields Offers a bridge to review literature and primary research on the inflammatory response towards medical application

Translational Autoimmunity, Volume 5

Translational Autoimmunity, Volume 5
  • Author : Nima Rezaei
  • Publisher : Elsevier
  • Release Date : 2022-09-23
  • Total pages : 420
  • ISBN : 9780323853903
  • File Size : 14,5 Mb
  • Total Download : 630
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Translational Autoimmunity: Challenges for Autoimmune Diseases, Fifth Edition addresses diagnostic approaches, therapeutic opportunities, and prognostic markers of different autoimmune diseases. This updated volume discusses autotoxicity, systems immunology, the prognostic significance of disease-specific autoantibodies, along with translational research to novel therapeutic policy in autoimmune diseases. From an introduction, to challenges and insights on the systems immunology of infectious and autoimmune diseases, new targets of treatments, and the role of autoantibodies in diagnosis and evolution, this book provides insights on many challenges researchers and clinicians are facing. Describes challenges in the diagnosis, management and treatment of autoimmune diseases Highlights major difficulties in the diagnosis and management of autoimmune diseases Reflects important remediable deficiencies in current management Meets the needs of basic scientists, clinicians and translational scientists and industry partners

Translational Autoimmunity

Translational Autoimmunity
  • Author : Nima Rezaei
  • Publisher : Academic Press
  • Release Date : 2022-04-01
  • Total pages : 404
  • ISBN : 9780323854160
  • File Size : 29,5 Mb
  • Total Download : 589
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Translational Autoimmunity: Autoimmune Diseases in Different Clinical Settings addresses autoimmunity and associated conditions, such as aging, infectious diseases, cancer, neurodegeneration, psychological disorders, fertility, inflammatory vascular diseases, and interstitial lung diseases. The book addresses sufficiently basic questions on how the immune system is designed to distinguish self from no self and behave such that it's able to maintain self-tolerance, how does it work in infections, and how it elicits an auto-reactive state and develops self-antigens seen in autoimmune conditions. This is followed by an overview on the genetic and clinical aspects of the spectrum of autoimmune diseases which are broadly categorized into two types of organ specific autoimmune diseases and non-organ specific autoimmune diseases (also known as systemic autoimmune diseases). Covers clinical aspects of autoimmunity and translational immunology studies in autoimmunity in different clinical settings Meets the needs of basic scientists, clinicians, translational scientists and industry partners Supported by a systematic appraisal of the most recent evidence

Recent Advances in Endothelial Progenitor Cells Toward Their Use in Clinical Translation

Recent Advances in Endothelial Progenitor Cells Toward Their Use in Clinical Translation
  • Author : Reinhold J. Medina,David M. Smadja
  • Publisher : Frontiers Media SA
  • Release Date : 2020-02-19
  • Total pages : 107
  • ISBN : 9782889634590
  • File Size : 9,6 Mb
  • Total Download : 732
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Since endothelial progenitor cells (EPCs) were first described in 1997, there has been significant debate surrounding their definition and roles; but also agreement in their potential to develop as biomarkers and cytotherapies. EPCs participate in vascular repair and postnatal angiogenesis by differentiating into endothelial cells or by producing pro–angiogenic growth factors. Various subtypes of EPCs have been studied, such as CD34+VEGFR2+ blood circulating cells, cultured endothelial colony forming cells (ECFCs), and myeloid angiogenic cells (MACs). EPCs have therapeutic potential for revascularisation and vascular repair in ischemic diseases such as myocardial infarction and diabetic vascular complications. In this eBook, we compile evidence to enable their translation including strategies to enhance the number, homing ability to the injury site and function of EPCs.

Translational Autoimmunity

Translational Autoimmunity
  • Author : Nima Rezaei
  • Publisher : Academic Press
  • Release Date : 2021-10-22
  • Total pages : 390
  • ISBN : 9780128232774
  • File Size : 40,6 Mb
  • Total Download : 707
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Translational Autoimmunity: Etiology of Autoimmune Diseases is the first volume of the Translational Immunology book series. To attain its purpose as a detailed translational step to tackle autoimmunity, this volume sufficiently addresses basic questions on how the immune system is designed to distinguish self from nonself. It discusses the known mechanisms that lead to the maintenance of self-tolerance, presents potential triggers and malfunctions that impede normal immune processes, and demonstrates how the immune system induces an autoreactive state that results in the recognition of self-antigens seen in autoimmune conditions. Includes coverage of basic immunology, the clinical aspects of autoimmunity, and translational immunology studies in autoimmunity Presents key concepts supported by a systematic appraisal of the most recent evidence Assists students at all the academic levels while also being applicable to scientists who work with autoimmunity Designed for learning, teaching, review, testing, practice and research

Pocket Primer on the Rheumatic Diseases

Pocket Primer on the Rheumatic Diseases
  • Author : John H. Klippel
  • Publisher : Springer
  • Release Date : 2010-03-01
  • Total pages : 242
  • ISBN : 1848828551
  • File Size : 17,6 Mb
  • Total Download : 672
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For eight decades the Primer on the Rheumatic Diseases has been the standard text from which most medical students and house ofcers have learned rheumatology. I myself will never forget thumbing through an older edition of the Primer as a second-year resident, while waiting to review a perplexing patient with my tutor. Fortunately the tutor was r- ning late with his own patients, so I had time to fip through the book – then much thinner – a couple of times. While turning the pages, per- ing the features of those diseases whose names were still exotic to me, and considering my patient’s history of conductive hearing loss and p- monary nodules, a light went on when I stumbled eventually on a part- ular chapter. I still remember the jaw-dropping efect on my tutor of my announcement then that I had a patient with Wegener’s granulomatosis. I think I became a rheumatologist that very moment! Subsequent editions of the Primer have sufered from the inevitable “obesity creep,” making it an outstanding reference textbook but virtually impossible to fip through quickly while awaiting one’s tutor, and even more difcult to slip into the pocket of a white coat to carry on rounds. For this reason we have created the Pocket Primer, a mini version that cuts the larger book down to its essentials.

DNA Methylation and Complex Human Disease

DNA Methylation and Complex Human Disease
  • Author : Michel Neidhart
  • Publisher : Academic Press
  • Release Date : 2015-08-11
  • Total pages : 552
  • ISBN : 9780127999203
  • File Size : 37,5 Mb
  • Total Download : 963
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DNA Methylation and Complex Human Disease reviews the possibilities of methyl-group-based epigenetic biomarkers of major diseases, tailored epigenetic therapies, and the future uses of high-throughput methylome technologies. This volume includes many pertinent advances in disease-bearing research, including obesity, type II diabetes, schizophrenia, and autoimmunity. DNA methylation is also discussed as a plasma and serum test for non-invasive screening, diagnostic and prognostic tests, as compared to biopsy-driven gene expression analysis, factors which have led to the use of DNA methylation as a potential tool for determining cancer risk, and diagnosis between benign and malignant disease. Therapies are at the heart of this volume and the possibilities of DNA demethylation. In cancer, unlike genetic mutations, DNA methylation and histone modifications are reversible and thus have shown great potential in the race for effective treatments. In addition, the authors present the importance of high-throughput methylome analysis, not only in cancer, but also in non-neoplastic diseases such as rheumatoid arthritis. Discusses breaking biomarker research in major disease families of current health concern and research interest, including obesity, type II diabetes, schizophrenia, and autoimmunity Summarizes advances not only relevant to cancer, but also in non-neoplastic disease, currently an emerging field Describes wholly new concepts, including the linking of metabolic pathways with epigenetics Provides translational researchers with the knowledge of both basic research and clinic applications of DNA methylation in human diseases

T Regulatory Cells in Human Health and Diseases

T Regulatory Cells in Human Health and Diseases
  • Author : Song-Guo Zheng
  • Publisher : Springer Nature
  • Release Date : 2021-02-01
  • Total pages : 302
  • ISBN : 9789811564079
  • File Size : 52,5 Mb
  • Total Download : 218
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This book addresses one of the major challenges of immunology today that is being directed to the translation of the rapidly emerging volume of basic science contributions of immunology to clinical medicine. In so doing, the book systemically introduces and discusses concepts, classifications, phenotypic and functional descriptions of regulatory T (Treg) cells in health and disease. The authors of the 15 chapters were selected from among the most qualified experts in the field of Treg cell research who provide a comprehensive overview of Treg cells and their biology in the ensuing chapters. The beginning chapters provide a useful contemporary classification of Treg cell populations and then progress to chapters that explore basic mechanisms of Treg cell function and epigenetic control. In addition to descriptions of typical CD4+ Foxp3+ cells, other chapters provide detailed presentations of Treg subsets such as CD8+ Tregs and IL-10-producing Tr1 cells. The differences of various Treg subsets, as well as circulating and resident Treg cell populations, are next compared. Importantly, the next chapters provide the clinical correlation of Treg cells with autoimmune diseases, inflammatory diseases, metabolic diseases, cancer and organ transplantation and progress to chapters that highlight emerging innovative technology including nanoparticle-Treg cells and their translational values. In summary, the book will provide a valuable resource not only for graduate students and researchers in the fields of immunology, cell biology and translational medicine but also for all others interested in learning more about Treg cells and their application in human health and disease.

Advances in Immunology

Advances in Immunology
  • Author : Anonim
  • Publisher : Elsevier
  • Release Date : 2022-12-01
  • Total pages : 142
  • ISBN : 9780323989480
  • File Size : 19,9 Mb
  • Total Download : 648
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Advances in Immunology, Volume 156, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology, with this volume covering self-referential immune recognition through C-type lectin receptors, genetic susceptibility to autoimmunity, activation and regulation of the cGAS-STING pathway and the implications of IL-15 trans-presentation on the immune response. Presents current developments and comprehensive reviews in immunology Provides the latest in a longstanding and respected serial on the subject matter Focuses on recent advances in the advancing area of the mechanisms involved in the evolution of regulatory T-cells in infection and Factor H and Properdin and their regulation

Autoimmune Diseases: Advances in Research and Treatment: 2011 Edition

Autoimmune Diseases: Advances in Research and Treatment: 2011 Edition
  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release Date : 2012-01-09
  • Total pages : 141
  • ISBN : 9781464927768
  • File Size : 54,7 Mb
  • Total Download : 117
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Autoimmune Diseases: Advances in Research and Treatment: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Autoimmune Diseases. The editors have built Autoimmune Diseases: Advances in Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Autoimmune Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Autoimmune Diseases: Advances in Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Progress in Molecular Biology and Translational Science

Progress in Molecular Biology and Translational Science
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2019-04-26
  • Total pages : 551
  • ISBN : 9780128177419
  • File Size : 38,9 Mb
  • Total Download : 852
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Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part B, Volume 163 in the Progress in Molecular Biology and Translational Science series, provides informative monographs on a variety of research topics related to Glycans and glycosaminoglycans as clinical biomarkers and therapeutics. Topics in this update include an Overview of Fugal Glycan-based Therapeutics, Heparin: An Essential Drug for Modern Medicine, Low Molecular Weight Heparins and Their Clinical Applications, The Clinical Use of Fondaparinux: A Synthetic Heparin Pentasaccharid, Heparinoids as Clinically Used Drugs, Marine Glycan-Derived Therapeutics in China, Efficacy of Heparinoid PSS in Treating Cardiovascular and other Diseases—30 Years Clinical Applications in China, and more. Includes comprehensive coverage of molecular biology Presents ample use of tables, diagrams, schemata and color figures to enhance the reader's ability to rapidly grasp the information provided Contains contributions from renowned experts in the field

Pathogenesis of Systemic Lupus Erythematosus

Pathogenesis of Systemic Lupus Erythematosus
  • Author : Alberta Hoi
  • Publisher : Springer Nature
  • Release Date : 2021-11-15
  • Total pages : 192
  • ISBN : 9783030851613
  • File Size : 52,5 Mb
  • Total Download : 172
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The scope of this contributed volume is to provide an overview of the latest translational research in the field of lupus pathogenesis, with particular emphasis on how these discoveries progress in parallel with therapeutic drug development. Systemic lupus erythematosus (SLE) is a multifaceted disease with a number of well-defined immune pathways that are dysregulated, resulting in an immune-mediated chronic inflammatory injury at target organs. As knowledge of these pathways evolves to provide opportunities for targeted drug therapy and lays the foundation for personalized medicine, clinicians and researchers need to keep up with the ever-expanding medical literature. This book will critically appraise the current understanding of important immunological pathways that contribute to the pathogenesis of lupus. We will review the role of interferons as part of the innate immune defects that perpetuate the loss of self-tolerance in SLE. B cell hyperactivity, as a defining hallmark of SLE, and different strategies of B cell targeted therapy will be discussed. The role of co-stimulation or immune checkpoint molecules in activating B and T cells will be reviewed, as well as other cytokines that serve in the amplification loop promoting a more proinflammatory Th1 or Th17 responses. Intracellular targets, such as signaling molecules in the JAK/STAT pathway, or a variety of kinases and proteasomes, can cause a cascading downstream effect of transcriptional responses that are important in SLE. Immune homeostasis can also be restored by bolstering the naturally occurring anti-inflammatory mechanisms. Glucocorticoid, as a potent natural anti-inflammatory hormone, can mediate its effects by recruiting histone deacetylase that serve to repress gene transcription. Glucocorticoid-induced leucine zipper is a gene upregulated by glucocorticoid that can be a potential target for development of anti-inflammatory strategy. Finally, T regulatory cells can be utilized to help restore to immune tolerance and are amongst the latest focus of therapeutic development in SLE.

Acute Rheumatic Fever and Rheumatic Heart Disease, E-Book

Acute Rheumatic Fever and Rheumatic Heart Disease, E-Book
  • Author : Dr. Scott Dougherty,Jonathan Carapetis,Nigel Wilson
  • Publisher : Elsevier Health Sciences
  • Release Date : 2020-02-22
  • Total pages : 362
  • ISBN : 9780323754606
  • File Size : 46,5 Mb
  • Total Download : 225
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Acute Rheumatic Fever and Rheumatic Heart Disease is a concise, yet comprehensive, clinical resource highlighting must-know information on rheumatic heart disease and acute rheumatic fever from a global perspective. Covering the major issues dominating the field, this practical resource presents sufficient detail for a deep and thorough understanding of the latest treatment options, potential complications, and disease management strategies to improve patient outcomes. Divided into four distinct sections for ease of navigation: Acute Rheumatic Fever, Rheumatic Heart Disease, Population-Based Strategies for Disease Control, and Acute and Emergency Presentations. International editors and chapter authors ensure a truly global perspective. Covers all clinical aspects, including epidemiology, pathophysiology, clinical features, diagnosis, management, and treatment. Includes key topics on population-based measures for disease control for effective primary, secondary, and tertiary prevention. Consolidates today’s available information and guidance into a single, convenient resource.

Kelley and Firestein's Textbook of Rheumatology E-Book

Kelley and Firestein's Textbook of Rheumatology E-Book
  • Author : Gary S. Firestein,Ralph Budd,Sherine E Gabriel,Iain B. McInnes,James R O'Dell
  • Publisher : Elsevier Health Sciences
  • Release Date : 2016-06-21
  • Total pages : 275
  • ISBN : 9780323414944
  • File Size : 18,9 Mb
  • Total Download : 841
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Download Kelley and Firestein's Textbook of Rheumatology E-Book in PDF, Epub, and Kindle

Consult the definitive resource in rheumatology for an in-depth understanding of scientific advances as they apply to clinical practice. Masterfully edited by Drs. Gary S. Firestein, Ralph C. Budd, Sherine E. Gabriel, Iain B. McInnes, and James R. O'Dell, and authored by internationally renowned scientists and clinicians in the field, Kelley and Firestein’s Textbook of Rheumatology, 10th Edition, delivers the knowledge you need for accurate diagnoses and effective patient care. From basic science, immunology, anatomy, and physiology to diagnostic tests, procedures, and specific disease processes, this state-of-the-art reference provides a global, authoritative perspective on the manifestations, diagnosis and treatment of rheumatic diseases. An ideal balance of the basic science you need to know and how to apply that information to clinical practice. An integrated chapter format allows you to review basic science advances and their clinical implications in one place and get dependable, evidence-based guidance for the full range of rheumatologic diseases and syndromes. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Metabolic Regulation of Immunity, Principles of Signaling, Research Methods in the Rheumatic Diseases, Novel Intracellular Targeting Agents, and IgG4-Related Diseases. New and expanded chapter topics on small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies. More schematic diagrams clearly summarize information and facilitate understanding.

Skills in Rheumatology

Skills in Rheumatology
  • Author : Hani Almoallim,Mohamed Cheikh
  • Publisher : Springer Nature
  • Release Date : 2021-01-05
  • Total pages : 566
  • ISBN : 9789811583230
  • File Size : 35,9 Mb
  • Total Download : 410
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This Open Access book presents practical approaches to managing patients affected by various rheumatological diseases, allowing readers to gain a better understanding of the various clinical expressions and problems experienced by these patients. Discussing rheumatology from an organ systems perspective, it highlights the importance ofdetailed musculoskeletal examinations when treating patients affected by rheumatological diseases. The book first explores the latest diagnostic approaches and offers key tips for accurate musculoskeletal examinations before addressing the various treatment modalities, with a particular focus on the most common joints involved in rheumatoid arthritis: the wrists and the metacarpophalangeal joints (2nd and 3rd). Featuring easy-to-understand flow diagrams and explaining the common medical problems associated with rheumatic disease, such as shortness of breath and anemia, it is not only a valuable resource to rheumatologists, but will also appeal to medical students, junior residents, and primary healthcare physicians.

Inflammatory Immune Disease: Molecular Mechanisms, Translational Approaches and Therapeutics

Inflammatory Immune Disease: Molecular Mechanisms, Translational Approaches and Therapeutics
  • Author : Tao Xu,Jian Gao,Sung Hwan Ki,Emanuela Ricciotti
  • Publisher : Frontiers Media SA
  • Release Date : 2022-07-05
  • Total pages : 1224
  • ISBN : 9782889747955
  • File Size : 42,9 Mb
  • Total Download : 525
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PDF book entitled Inflammatory Immune Disease: Molecular Mechanisms, Translational Approaches and Therapeutics written by Tao Xu,Jian Gao,Sung Hwan Ki,Emanuela Ricciotti and published by Frontiers Media SA which was released on 2022-07-05 with total hardcover pages 1224, the book become popular and critical acclaim.

Comorbidity in Rheumatic Diseases

Comorbidity in Rheumatic Diseases
  • Author : Yasser El Miedany
  • Publisher : Springer
  • Release Date : 2017-08-24
  • Total pages : 433
  • ISBN : 9783319599632
  • File Size : 26,7 Mb
  • Total Download : 909
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This book explores comorbidity in patients with rheumatic diseases and details both care and treatment options in standard clinical practice. Patients with rheumatic diseases are clinically complex, and the interplay of their disease activity with associated conditions may lead to increased morbidity and mortality. Recently there have been major advances in the management of rheumatic diseases, however, without addressing the potential comorbid conditions, including cardiovascular disease; pulmonary disease; and depression; outcomes remain poor. ​​​ With its 19 chapters, covering the management of major rheumatic diseases (e.g. rheumatoid arthritis, systemic lupus erythematosus , and osteoarthritis), potential comorbidities and treatment recommendations, as well as possible interactions between conditions; this book addresses the gap between textbook medicine and day to day patients' care. Authors also discuss the new hot issue of the comorbidity index, comparing the standard tools to the recently developed indices and how they can assist the rheumatologists in determining disease burden, prognosis, and comorbidity probability. This book is an ideal clinical guide and reference that enables rheumatologists, internal medicine physicians, and residents to address the full clinical expression of these rheumatic diseases with views towards prevention or early management of comorbid conditions.