The Zebrafish In Biomedical Research

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The Zebrafish in Biomedical Research

The Zebrafish in Biomedical Research
  • Author : Samuel Cartner,Judith S. Eisen,Susan F. Farmer,Karen J. Guillemin,Michael L. Kent,George E. Sanders
  • Publisher : Academic Press
  • Release Date : 2019-11-22
  • Total pages : 718
  • ISBN : 9780128124321
  • File Size : 28,9 Mb
  • Total Download : 538
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The Zebrafish in Biomedical Research: Biology, Husbandry, Diseases, and Research Applications is a comprehensive work that fulfills a critical need for a thorough compilation of information on this species. The text provides significant updates for working vivarium professionals maintaining zebrafish colonies, veterinarians responsible for their care and well-being, zoologists and ethologists studying the species, and investigators using the species to gain critical insights into human physiology and disease. As the zebrafish has become an important model organism for the study of vertebrate development and disease, organ function, behavior, toxicology, cancer, and drug discovery, this book presents an important resource for future research. Presents a complete view of the zebrafish, covering their biology, husbandry, diseases and research applications Includes the work of world-renowned authors Provides the first authoritative and comprehensive treatment of zebrafish in biomedical research as part of the ACLAM series

Laboratory Fish in Biomedical Research

Laboratory Fish in Biomedical Research
  • Author : Livia d'Angelo,Paolo de Girolamo
  • Publisher : Academic Press
  • Release Date : 2021-08-28
  • Total pages : 474
  • ISBN : 9780128212455
  • File Size : 28,8 Mb
  • Total Download : 329
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Fish, and particularly zebrafish, have become the fastest-growing segment of the research population. They offer several advantages, in terms of biology and technologies to apply, and thus are employed in numerous research fields. Laboratory Fish in Biomedical Research: Biology, Husbandry and Research Applications for Zebrafish, Medaka, Killifish, Swordtail Fish, Cavefish, Stickleback, Goldfish and Danionella Translucida addresses the relevant and increasing need to collect cutting-edge knowledge on husbandry, maintenance, welfare and experimental protocols of the most common freshwater species under standard laboratory conditions. Provides husbandry and management protocols, devices and water systems Shows strength and weakness of breeding Explores potential scientific applications and experimental protocols. with regards to the most used freshwater fish used for scientific purposes

The Zebrafish in Biomedical Research

The Zebrafish in Biomedical Research
  • Author : Samual Cartner,Judith S. Eisen,Susan F. Farmer,Karen J. Guillemin,Michael L. Kent,George Lawrence Sanders
  • Publisher : Academic Press
  • Release Date : 2019-08-15
  • Total pages : 550
  • ISBN : 0128124318
  • File Size : 14,9 Mb
  • Total Download : 515
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Download The Zebrafish in Biomedical Research in PDF, Epub, and Kindle

The Zebrafish in Biomedical Research: Biology, Husbandry, Diseases, and Research Applications is a comprehensive work that fulfills a critical need for a thorough compilation of information on this species. The text provide significant updates for working vivarium professionals maintaining zebrafish colonies, veterinarians responsible for their care and well-being, zoologists and ethologists studying the species, and investigators using the species to gain critical insights into human physiology and disease. As the zebrafish has become an important model organism for the study of vertebrate development and disease, organ function, behavior, toxicology, cancer, and drug discovery, this book presents an important resource for future research. Presents a complete view of the zebrafish, covering their biology, husbandry, diseases and research applications Includes the work of world-renowned editors Provides the first authoritative and comprehensive treatment of zebrafish in biomedical research as part of the ACLAM series

Zebrafish in Biomedical Research

Zebrafish in Biomedical Research
  • Author : Yusuf Bozkurt
  • Publisher : Unknown
  • Release Date : 2020-03
  • Total pages : 229
  • ISBN : 1789859859
  • File Size : 23,9 Mb
  • Total Download : 806
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PDF book entitled Zebrafish in Biomedical Research written by Yusuf Bozkurt and published by Unknown which was released on 2020-03 with total hardcover pages 229, the book become popular and critical acclaim.

Zebrafish Model for Biomedical Research

Zebrafish Model for Biomedical Research
  • Author : Prasan R. Bhandari,Kala Kumar Bharani,Amit Khurana
  • Publisher : Springer Nature
  • Release Date : 2022-05-30
  • Total pages : 490
  • ISBN : 9789811652172
  • File Size : 26,7 Mb
  • Total Download : 424
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This book provides the latest information on the significance of zebrafish as an ideal model for researching the biomedical field, with references. This book also focused on the evidence of zebrafish as a model in cardiovascular, neurologic, psychiatric and metabolic research. In addition, the book also includes the research carried out on zebrafish in hepatic, renal, ophthalmic, and ENT related areas. Contributed chapters come from the most prominent laboratories working in this field, which provides a unique perspective on zebrafish models from a wide spectrum of the research community. In addition, the book offers a detailed analysis of the most current research in the area for specific zebrafish models including specific research in the area of skin disorders, endocrine diseases, nutritional disorders, gastrointestinal, hematological disorders and cancer. The compilation of chapters in the volume culminates into a comprehensive and definitive text on zebrafish and its suitability for modeling various diseases, providing a critical resource on the potential attributes of the zebrafish as a pharmacological model. In terms of scope, this book is a useful tool for young researchers, professors and pharmaceutical scientists for understanding the significance of zebrafish as an emerging pharmacological model that can significantly aid in the process of drug discovery and development.

Sourcebook of Models for Biomedical Research

Sourcebook of Models for Biomedical Research
  • Author : P. Michael Conn
  • Publisher : Springer Science & Business Media
  • Release Date : 2008-03-07
  • Total pages : 778
  • ISBN : 9781597452854
  • File Size : 17,7 Mb
  • Total Download : 641
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The collection of systems represented in this volume is a unique effort to reflect the diversity and utility of models used in biomedicine. That utility is based on the consideration that observations made in particular organisms will provide insight into the workings of other, more complex systems. This volume is therefore a comprehensive and extensive collection of these important medical parallels.

Basic Science Methods for Clinical Researchers

Basic Science Methods for Clinical Researchers
  • Author : Morteza Jalali,Francesca Yvonne Louise Saldanha,Mehdi Jalali
  • Publisher : Academic Press
  • Release Date : 2017-03-31
  • Total pages : 382
  • ISBN : 9780128030783
  • File Size : 18,5 Mb
  • Total Download : 853
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Basic Science Methods for Clinical Researchers addresses the specific challenges faced by clinicians without a conventional science background. The aim of the book is to introduce the reader to core experimental methods commonly used to answer questions in basic science research and to outline their relative strengths and limitations in generating conclusive data. This book will be a vital companion for clinicians undertaking laboratory-based science. It will support clinicians in the pursuit of their academic interests and in making an original contribution to their chosen field. In doing so, it will facilitate the development of tomorrow’s clinician scientists and future leaders in discovery science. Serves as a helpful guide for clinical researchers who lack a conventional science background Organized around research themes pertaining to key biological molecules, from genes, to proteins, cells, and model organisms Features protocols, techniques for troubleshooting common problems, and an explanation of the advantages and limitations of a technique in generating conclusive data Appendices provide resources for practical research methodology, including legal frameworks for using stem cells and animals in the laboratory, ethical considerations, and good laboratory practice (GLP)

Animal-centric Care and Management

Animal-centric Care and Management
  • Author : Dorte Bratbo Sørensen,Sylvie Cloutier,Brianna N. Gaskill
  • Publisher : CRC Press
  • Release Date : 2020-10-14
  • Total pages : 190
  • ISBN : 9780429602054
  • File Size : 37,8 Mb
  • Total Download : 308
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The concept of the 3Rs (Refinement, Reduction and Replacement) has been used as a framework for improving the welfare of laboratory animals for the last half century. By establishing an animal-centric view on housing and management, Animal-centric Care and Management: Enhancing Refinement in Biomedical Research takes Russell and Burch’s definition of Refinement as "elimination of inhumanities" and goes further. Rather than fitting animals into experimental conditions, it encourages readers to adjust conditions to better meet the behavioral, emotional, physical, and physiological needs and preferences of the animals. The team of expert authors, from the fields of laboratory animal science, ethology, biology as well as animal training, provide ideas for creating housing conditions and handling procedures that induce, to the best of current abilities and knowledge, a long-term positive state of mind in the animals under our care. This book is written for animal caretakers, animal health technicians, researchers, animal facility managers, laboratory animal veterinarians, and anyone who engages in work with living experimental animals or is interested in the continuous improvement of laboratory animal welfare. This interdisciplinary guide will act as a catalyst, resulting in multiple viewpoints and fields collaborating to optimize laboratory animal welfare.

Laboratory Animal Medicine

Laboratory Animal Medicine
  • Author : James G. Fox,Bennett J. Cohen,Franklin M. Loew
  • Publisher : Academic Press
  • Release Date : 2013-10-02
  • Total pages : 766
  • ISBN : 9781483269160
  • File Size : 45,9 Mb
  • Total Download : 228
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Laboratory Animal Medicine is a compilation of papers that deals with the diseases and biology of major species of animals used in medical research. The book discusses animal medicine, experimental methods and techniques, design and management of animal facilities, and legislation on laboratory animals. Several papers discuss the biology and diseases of mice, hamsters, guinea pigs, and rabbits. Another paper addresses the dog and cat as laboratory animals, including sourcing of these animals, housing, feeding, and their nutritional needs, as well as breeding and colony management. The book also describes ungulates as laboratory animals, including topics on sourcing, husbandry, preventive medical treatments, and housing facilities. One paper addresses primates as test animals, covering the biology and diseases of old world primates, Cebidae, and ferrets. Some papers pertain to the treatment, diseases, and needed facilities for birds, amphibians, and fish. Other papers then deal with techniques of experimentation, anesthesia, euthanasia, and some factors (spontaneous diseases) that complicate animal research. The text can prove helpful for scientists, clinical assistants, and researchers whose work involves laboratory animals.

Behavioral Biology of Laboratory Animals

Behavioral Biology of Laboratory Animals
  • Author : Kristine Coleman,Steven J. Schapiro
  • Publisher : CRC Press
  • Release Date : 2021-09-01
  • Total pages : 560
  • ISBN : 9780429671296
  • File Size : 14,6 Mb
  • Total Download : 254
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This 30-chapter volume informs students and professionals about the behavioral biology of animals commonly housed in laboratory and other captive settings. Each species evolved under specific environmental conditions, resulting in unique behavioral patterns, many of which are maintained in captivity even after generations of breeding. Understanding natural behavior is therefore a critical part of modern animal care practices. The descriptions, data, guidance, resources, and recommendations in this book will help the reader understand their animals better, refine the care and treatment that they receive, and improve the well-being, welfare, and wellness of their animals. The book is divided into three sections, all focusing on aspects of the behavioral biology of animals found in laboratories and related research settings. After five introductory chapters, 25 chapters are dedicated to specific taxonomic groups (including mice, zebrafish, zebra finches, reptiles, macaques) while a concluding section of ethograms provides a centralized resource for those interested in understanding, and potentially quantifying, animal behavior. The Behaviorial Biology of Laboratory Animals will provide anyone working in maintenance, care, and/or research programs that involve laboratory animals with information about the way the animals live in the wild, and the way that they should live in captive research settings. Many of the guidelines and recommendations will also be valuable to those managing and working with animals in other environments, including zoological parks, aquaria, and sanctuaries.

Sourcebook of Models for Biomedical Research

Sourcebook of Models for Biomedical Research
  • Author : P. Michael Conn
  • Publisher : Springer Science & Business Media
  • Release Date : 2008
  • Total pages : 756
  • ISBN : 9781588299338
  • File Size : 16,5 Mb
  • Total Download : 949
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The collection of systems represented in this volume is a unique effort to reflect the diversity and utility of models used in biomedicine. That utility is based on the consideration that observations made in particular organisms will provide insight into the workings of other, more complex systems. This volume is therefore a comprehensive and extensive collection of these important medical parallels.

Laboratory Fish in Biomedical Research

Laboratory Fish in Biomedical Research
  • Author : Livia d'Angelo,Paolo de Girolamo
  • Publisher : Elsevier
  • Release Date : 2021-09-06
  • Total pages : 474
  • ISBN : 9780128210994
  • File Size : 22,8 Mb
  • Total Download : 499
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"Fish, particularly zebrafish, have become the fatest-growing segment of the research population. They offer several advantages in biology and applicable technologies and thus are employed in numerous research fields. Laboratory Fish in Biomedical Research: Biology, Husbandry and Research Applications for Zebrafish, Medaka, Killifish, Cavefish, Stickleback, Goldfish and Danionella translucida addresses the relevant, increasing need to collect cutting-edge knowledge on the most common freshwater species in terms of husbandry, maintenance, welfare, and experimental protocols under standard laboratory conditions. Key features: provides husbandry and management protocols, devices, and water systems; discusses strengths and weaknesses of breeding; explores potential scientific applications and experimental protocols of freshwater fish used the most in scientific endeavors."--Back cover.

The Zebrafish: Disease Models and Chemical Screens

The Zebrafish: Disease Models and Chemical Screens
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2011-09-09
  • Total pages : 616
  • ISBN : 9780123813213
  • File Size : 44,5 Mb
  • Total Download : 887
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This volume of Methods in Cell Biology is the 3e, and provides comprehensive compendia of laboratory protocols and reviews covering all the new methods developed since 2004. This new volume on Disease Models and Chemical Screens, covers two rapidly emerging and compelling applications of the zebrafish. Details state-of-the art zebrafish protocols, delineating critical steps in the procedures as well as potential pitfalls This volume concentrates on Disease Models and Chemical Screens

Zebrafish in Development and Disease

Zebrafish in Development and Disease
  • Author : Gokhan Dalgin,Rebecca Ann Wingert,Ryan M. Anderson
  • Publisher : Frontiers Media SA
  • Release Date : 2019-12-06
  • Total pages : 157
  • ISBN : 9782889632480
  • File Size : 20,7 Mb
  • Total Download : 466
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There are only a few vertebrate systems that can be used to model human diseases for biomedical discovery. The zebrafish model provides key advantages over existing models. Their externally developing embryos provide high-throughput non-invasive imaging, chemical screening, forward and reverse genetics, and their regeneration capacity make zebrafish a valuable system for novel discovery. Developmental studies using zebrafish has influenced discoveries in many human health-related conditions. This Research Topic covers all aspects of zebrafish studies, providing developmental mechanisms to human health conditions. The aim of the Research Topic was to foster a platform to bring all levels of zebrafish research including but not limited to development, disease, regeneration, drug screening, bioinformatics and Omics studies.

Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants

Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants
  • Author : Yvonne Will,James A. Dykens
  • Publisher : John Wiley & Sons
  • Release Date : 2018-03-23
  • Total pages : 816
  • ISBN : 9781119329749
  • File Size : 54,6 Mb
  • Total Download : 719
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Developed as a one-stop reference source for drug safety and toxicology professionals, this book explains why mitochondrial failure is a crucial step in drug toxicity and how it can be avoided. • Covers both basic science and applied technology / methods • Allows readers to understand the basis of mitochondrial function, the preclinical assessments used, and what they reveal about drug effects • Contains both in vitro and in vivo methods for analysis, including practical screening approaches for drug discovery and development • Adds coverage about mitochondrial toxicity underlying organ injury, clinical reports on drug classes, and discussion of environmental toxicants affecting mitochondria

Advancements of Mass Spectrometry in Biomedical Research

Advancements of Mass Spectrometry in Biomedical Research
  • Author : Alisa G. Woods,Costel C. Darie
  • Publisher : Springer
  • Release Date : 2014-06-20
  • Total pages : 600
  • ISBN : 9783319060682
  • File Size : 33,7 Mb
  • Total Download : 194
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This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease and psychiatry. Additional chapters focus on methodology as well as new technologies and instrumentation. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research but also to initiate and improve their own work. Thus the book acts as a technical guide but also a conceptual guide to the newest information in this exciting field. Mass spectrometry is the central tool used in proteomic research today and is rapidly becoming indispensable to the biomedical scientist. With the completion of the human genome project and the genomic revolution, the proteomic revolution has followed closely behind. Understanding the human proteome has become critical to basic and clinical biomedical research and holds the promise of providing comprehensive understanding of human physiological processes. In addition, proteomics and mass spectrometry are bringing unprecedented biomarker discovery and are helping to personalize medicine.

Zebrafish Protocols for Neurobehavioral Research

Zebrafish Protocols for Neurobehavioral Research
  • Author : Allan V. Kalueff, Laporte,Adam Michael Stewart
  • Publisher : Humana Press
  • Release Date : 2016-05-01
  • Total pages : 376
  • ISBN : 1493960024
  • File Size : 16,5 Mb
  • Total Download : 695
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Zebrafish play an integral role in biomedical research, enabling scientists to examine physiological mechanisms and pathways relevant to human pathogenesis and its therapy. Written by experts, this volume sets out protocols for both larval and adult models.

Guide for the Care and Use of Laboratory Animals

Guide for the Care and Use of Laboratory Animals
  • Author : National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Committee for the Update of the Guide for the Care and Use of Laboratory Animals
  • Publisher : National Academies Press
  • Release Date : 2011-01-27
  • Total pages : 246
  • ISBN : 9780309154000
  • File Size : 34,8 Mb
  • Total Download : 956
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A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

Recent Advances in Zebrafish Researches

Recent Advances in Zebrafish Researches
  • Author : Yusuf Bozkurt
  • Publisher : BoD – Books on Demand
  • Release Date : 2018-05-30
  • Total pages : 219
  • ISBN : 9781789231724
  • File Size : 48,5 Mb
  • Total Download : 241
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Model organisms have been used in various disciplines in order to understand different mechanisms underlying the problems. From this point of view, the zebrafish has become a favorite model organism in different scientific research fields in recent years because of its rapid embryonic development, transparency of its embryos, and its large number of offspring along with several other advantages. Recent Advances in Zebrafish Researches demonstrates the role and the function of zebrafish in different research fields and totally includes 11 chapters, which have been written by the expert researches in their fields. With this book, every researcher will better understand different mechanisms underlying the problems at different disciplines using zebrafish as model organism.

The Laboratory Zebrafish

The Laboratory Zebrafish
  • Author : Claudia Harper,Christian Lawrence
  • Publisher : CRC Press
  • Release Date : 2016-04-19
  • Total pages : 274
  • ISBN : 9781439807446
  • File Size : 48,8 Mb
  • Total Download : 899
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Like other books in the Laboratory Animal Pocket Reference Series, this guide covers all aspects pertaining to the use of these organisms including their basic biology, humane care and management, husbandry, life support systems, regulatory compliance, technical procedures, veterinary care, and water quality management. In the relatively brief span of only a few decades, the zebrafish has gone from being mainly a hobby fish to a mainstream model animal employed by scientists to study everything from stem cells to the basis of behavioral changes induced by drug addiction. This rapid advance has been fueled largely by numerous and impressive advances in technology, along with detailed characterization of the animal on a genetic and molecular level. These developments have allowed scientists to leverage the many advantages of the zebrafish system to address many important questions in biology and human genetics and disease. However, there are few accepted and established standards for husbandry, management, and care for the fish in laboratory settings and even fewer comprehensive and constantly reliable resources. To this end, the goal of this handbook is to provide managers, veterinarians, investigators, technicians, and regulatory personnel with a concise yet thorough reference on zebrafish biology, care, husbandry, and management. The aim of the book is not to set standards, but rather to arm those working with the fish with scientifically grounded principles and fundamental information that can be used to design sound fish care programs. This handbook is organized into seven chapters: Biology Husbandry Life Support Systems Management Veterinary Care Experimental Methodology Resources The final chapter, Resources, provides the zebrafish user with lists of sources of additional information on the zebrafish model, as well as key references, professional organizations, and suppliers of equipment and supplies used in zebrafish husbandry and care.

Anesthesia and Analgesia in Laboratory Animals

Anesthesia and Analgesia in Laboratory Animals
  • Author : Richard Fish,Peggy J. Danneman,Marilyn Brown,Alicia Karas
  • Publisher : Academic Press
  • Release Date : 2011-04-28
  • Total pages : 672
  • ISBN : 9780080559834
  • File Size : 21,5 Mb
  • Total Download : 889
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Anesthesia and Analgesia in Laboratory Animals focuses on the special anesthetic, analgesic, and postoperative care requirements associated with experimental surgery. Fully revised and updated this new edition provides the reader with agents, methods, and techniques for anesthesia and analgesia that ensure humane and successful procedural outcomes. * Provides researchers with the most comprehensive and up-to-date review of the use of anesthesia and analgesia in laboratory animals * Thoroughly updated with new material on ferrets, birds, reptiles, amphibians, fish, and invertebrates * Includes hot topic areas such as pain research, ethical issues, legal issues, and imaging studies