The Rose And Mackay Textbook Of Autoimmune Diseases

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• Author : Ian R. Mackay,Noel R Rose
• Publisher : Academic Press
• Release Date : 2013-12-03
• Total pages : 1304
• ISBN : 9780123849304
• File Size : 39,8 Mb
• Total Download : 527
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Download The Autoimmune Diseases in PDF, Epub, and Kindle

Since publication of the 4th Edition of The Autoimmune Diseases in 2006, the understanding of the immune mechanisms underlying autoimmunity and autoimmune disease has significantly deepened and broadened. This fully revised 5th Edition incorporates new material and combines common themes underlying inductive and effector mechanisms and therapies that relate generally to the autoimmune disorders. It discusses the biological basis of disease at genetic, molecular, cellular, and epidemiologic levels and includes expanded coverage of autoinflammatory disease and autoimmune responses to tumors. Gives a thorough and an important overview on the entire field, framing individual disease chapters with information that compares and contrasts each disorder and therapy Provides thorough, up-to-date information on specific diseases, along with clinical applications, in an easily found reference for clinicians and researchers interested in certain diseases Keeps readers abreast of current trends and emerging areas in the field Ensures that content is not only up-to-date, but applicable and relevant

• Author : Eric Gershwin,George Tsokos,Betty Diamond,Charles Mackay
• Publisher : Academic Press
• Release Date : 2023-06-01
• Total pages : 0
• ISBN : 0443186472
• File Size : 25,9 Mb
• Total Download : 780
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Download The Rose and Mackay Textbook of Autoimmune Diseases in PDF, Epub, and Kindle

In dedication of Professor Rose and Professor Mackay who both passed away in 2020. A global group on experts in the field updated this Seventh Edition of The Autoimmune Diseases. The Rose-Mackay Textbook of Autoimmune Diseases, is a comprehensive reference that emphasizes the "3 P's" of 21st Century medicine: precision, prediction, and prevention. Topics cover the modern systems approach to biology that involves large amounts of personalized, ongoing physiologic data ("omics") coupled with advanced methods of analysis, new tests of genetic engineering, such as CRISPR, auto inflammatory diseases, autoimmune responses to tumor immunotherapy, and information on normal immune response and disorders. Each of the major autoimmune disorders is discussed by researchers and clinical investigators experienced in dealing with patients. The new edition continues its success with 75% of the content revised, updated, or completely new. This edition is a valuable resource to clinicians involved in the diagnosis and treatment of autoimmune disease, as well as to scientists who want to follow developments in the field.

• Author : Noel R. Rose,Ian R. Mackay
• Publisher : Academic Press
• Release Date : 2019-10-15
• Total pages : 1532
• ISBN : 9780128122426
• File Size : 41,9 Mb
• Total Download : 970
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Download The Autoimmune Diseases in PDF, Epub, and Kindle

The Autoimmune Diseases, Sixth Edition, emphasizes the "3 P’s" of 21st Century medicine: precision, prediction and prevention. Topics cover the modern systems approach to biology that involves large amounts of personalized, ongoing physiologic data ("omics") coupled with advanced methods of analysis, new tests of genetic engineering, such as CRISPR, auto inflammatory diseases, autoimmune responses to tumor immunotherapy, and information on normal immune response and disorders. Each of the major autoimmune disorders is discussed by researchers and clinical investigators experienced in dealing with patients. Chapters emphasize the immunologic basis of the disease as well as the use of immunologic diagnostic methods and treatments. The book also covers several cross-cutting issues related to the recognition and treatment of autoimmune diseases, including chapters on the measurement of autoantibodies and T cells, the use of biomarkers as early predictors of disease, and new methods of treatment. Gives a thorough and important overview on the entire field, framing individual disease chapters with information that compares and contrasts each disorder and its therapy Provides thorough, up-to-date information on specific diseases, along with clinical applications in an easily found reference for clinicians and researchers interested in certain diseases Keeps readers abreast of current trends and emerging areas in the field Ensures that content is not only up-to-date, but applicable and relevant Includes new, updated chapters that emphasize hot topics in the field, e.g., research on auto inflammatory diseases and autoimmune responses following cancer immunotherapy

• Author : Warwick Anderson,Ian R. Mackay
• Publisher : JHU Press
• Release Date : 2014-11-15
• Total pages : 265
• ISBN : 9781421415338
• File Size : 45,6 Mb
• Total Download : 831
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Download Intolerant Bodies in PDF, Epub, and Kindle

"A unique collaboration between Ian Mackay, one of the prominent founders of clinical immunology, and Warwick Anderson, a leading historian of twentieth-century biomedical science. Connection laboratory research, clinical medicine, social theory, and lived experience, the authors reveal how doctors and patients have come to terms with this new concept of pathogenesis, one that was accepted only in the 1950s." --

• Author : Ian R. Mackay,Noel R. Rose
• Publisher : Unknown
• Release Date : 2019
• Total pages : 229
• ISBN : 1461492092
• File Size : 15,7 Mb
• Total Download : 944
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Download Encyclopedia of Medical Immunology in PDF, Epub, and Kindle

Offering a broad appeal to microbiologists, immunologists, and infectious disease specialists, this four volume encyclopedia covers all autoimmune, tropical, and infectious diseases. Emphasis will also be placed on genetics, physiology, metabolism, pathogenesis and applied microbiology. Under the leadership of some of the most world renowned names in the field, the encyclopedia will bring together an outstanding collection of contributions by top scientists in a variety of fields. Volumes 1-3: Diseases will be divided by the 11 main sections of the body, namely Integumentary, Skeletal, Respiratory, Digestive, Urinary, and Reproductive. For some of the autoimmune disease, more then one system will be involved but the delineation serves to broadly break down the diseases into systems. Volume 4 will cover the vaccines for said diseases and future prospects will be offered by leaders in industry and academia. Volume 4 will also be broken down into all the body systems, as in the other two volumes. For each vaccine, for each disease, and in each system the following will be included: • A list of the vaccines currently available along with a list of the companies that manufacture them • Molecular Immunology of the Vaccine • Type of Immunity involved in protection • Mode of Vaccination for each vaccine; repeated boosters and length of immunological memory • Commercial production of vaccines • Storage of vaccines • Standardization and Control of Vaccines • WHO programs and World-Wide Disease Eradication Programs based upon Vaccines.

• Author : Ian Mackay,Noel R. Rose,Shan Lu
• Publisher : Springer
• Release Date : 2018-09-11
• Total pages : 0
• ISBN : 1461491967
• File Size : 18,6 Mb
• Total Download : 535
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Download Encyclopedia of Medical Immunology in PDF, Epub, and Kindle

Offering a broad appeal to microbiologists, immunologists, and infectious disease specialists, the volume provides current and future prospects of vaccines for all autoimmune, tropical, and infectious diseases. Emphasis is placed on genetics, physiology, metabolism, pathogenesis, and applied microbiology. Under the leadership of some of the most world renowned names in the field, the encyclopedia brings together an outstanding collection of contributions by top scientists in a variety of fields. The entries are listed alphabetically and provide full references. The volume on Vaccines includes: • A list of the vaccines currently available and the companies that manufacture them • Molecular Immunology of the Vaccine • Type of Immunity involved in protection • Mode of Vaccination for each vaccine; repeated boosters and length of immunological memory • Commercial production of vaccines • Storage of vaccines • Standardization and Control of Vaccines • WHO programs and World-Wide Disease Eradication Programs based upon Vaccines

• Author : Noel R. Rose,Ian R. Mackay
• Publisher : Unknown
• Release Date : 1992
• Total pages : 472
• ISBN : UOM:39015022243292
• File Size : 38,7 Mb
• Total Download : 747
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Download The Autoimmune Diseases II in PDF, Epub, and Kindle

This book deals with autoimmune disease in humans (as opposed to autoimmunity itself). It discusses the biological basis of disease at the molecular, genetic, cellular, and epidemiologic levels. It also describes the clinical problems of diagnosis, prognosis, and treatment. The intended audience includes physicians of all specialties in practice, physicians in training such as house staff and fellows, and medical students. It will also be valuable for basic scientists and graduate students interested in the solution of important clinical problems. The book concentrates on topics that have grown or changed dramatically since publication of The Autoimmune Diseases.

• Author : W.J. van Venrooij,Ravinder N. Maini
• Publisher : Springer Science & Business Media
• Release Date : 2012-12-06
• Total pages : 742
• ISBN : 9789401116701
• File Size : 54,5 Mb
• Total Download : 107
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Download Manual of Biological Markers of Disease in PDF, Epub, and Kindle

A comprehensive reference work: This looseleaf work is an authoritative compilation of methods for the detection of autoantibodies (Section A: Methods of Autoantibody Detection); the structure, function, and molecular and biochemical concepts of autoantigens (Section B: Autoantigens); and the clinical significance of measuring autoantibodies in patients with rheumatic, connective tissue and autoimmune diseases (Section C: Clinical Significance of Autoantibodies). This unique work brings together all the molecular and medical information - very difficult to retrieve otherwise - in ONE publication. The Editors and contributors are leading experts in the immunological, molecular biological, and clinical fields. The format of this looseleaf publication allows regular updating of data as well as inclusion of new advances in research on autoimmunity. Until now, the work (Basic work including Supplement 1) included Section A, and the larger part of Section B, both in an attractive and robust ringbinder. Audience: By nature and design of this exciting reference work, it is especially aimed at scientists, including immunologists, pathologists and molecular biologists, and clinical chemists, as well as clinicians specializing in rheumatic diseases and autoimmune disorders, inflammation or clinical immunology. Supplement 2: This supplement primarily contains Section C (Clinical Significance of Autoantibodies). As in the other sections, the contents are presented in a consistently structured manner, beautifully illustrated with photos and schematic figures. Extensive literature references are provided. Also, this supplement includes an addition to Section B (Autoantigens), being chapter B.1.5: The Antigens Defined by Antikeratin Antibodies (AKA).

• Author : Ana Martinez
• Publisher : Royal Society of Chemistry
• Release Date : 2019-06-28
• Total pages : 350
• ISBN : 9781788014502
• File Size : 45,7 Mb
• Total Download : 555
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Download Emerging Drugs and Targets for Multiple Sclerosis in PDF, Epub, and Kindle

Multiple sclerosis (MS) is a complex disease with a presumed autoimmune aetiology and few current effective treatments. Disease modifying therapies focus on the altering the natural course of relapsing and remitting MS, targeting the inflammatory response. Other targets involve tacking the cause of the disease – demyelination of axons through remyelination therapies. Due to several recent breakthroughs in the understanding of the pathophysiology of MS new targets for remyelination and immunomodulation are rapidly emerging. This book provides a comprehensive overview of drug discovery and development for the molecular basis of the disease, from new targets to drugs currently in clinical development, cellular and animal disease models to biomarkers for diagnosis and assessment in clinical trials. Emerging Drugs and Targets for Multiple Sclerosis is an ideal reference for any student or researcher interested in drug development for neurodegenerative diseases, autoimmune diseases and MS in particular.

• Author : Philip Conaghan,Chris Denton,Helen Foster,John Isaacs
• Publisher : Oxford University Press
• Release Date : 2013-10
• Total pages : 1553
• ISBN : 9780199642489
• File Size : 27,9 Mb
• Total Download : 429
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Download Oxford Textbook of Rheumatology in PDF, Epub, and Kindle

A strong clinical emphasis is present throughout this volume from the first section of commonly presenting problems through to the section addressing problems shared with a range of other clinical sub-specialties.

• Author : R.C. Kennedy,S. Ferrone,Yehuda Shoenfeld
• Publisher : Elsevier
• Release Date : 1997-11-19
• Total pages : 540
• ISBN : 0080534430
• File Size : 35,9 Mb
• Total Download : 924
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Download Idiotypes in Medicine: Autoimmunity, Infection and Cancer in PDF, Epub, and Kindle

This is the most comprehensive review of the idiotypic network available. All the current knowledge of idiotypes of the various antibodies is incorporated in this volume. The pathogenic role of idiotypes in autoimmunity and cancer is reviewed in depth. The therapeutic part focusses on harnessing anti-idiotypes for treating autoimmunological disorders, and on the employment of idiotypes for vaccines in cancer and infectious diseases, as well as explaining the manipulation of the idiotypic network in autoimmunity and cancer idiotypes and vaccines.

• Author : Institute of Medicine,Board on Population Health and Public Health Practice,Committee to Review Adverse Effects of Vaccines
• Publisher : National Academies Press
• Release Date : 2012-04-26
• Total pages : 894
• ISBN : 9780309214353
• File Size : 16,8 Mb
• Total Download : 560
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Download Adverse Effects of Vaccines in PDF, Epub, and Kindle

In 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases. Today, vaccines exist for many viral and bacterial diseases. The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens. The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers. A key component of the legislation required the U.S. Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children. Adverse Effects of Vaccines reviews the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the National Vaccine Injury Compensation Program (VICP), including the varicella zoster vaccine, influenza vaccines, the hepatitis B vaccine, and the human papillomavirus vaccine, among others. For each possible adverse event, the report reviews peer-reviewed primary studies, summarizes their findings, and evaluates the epidemiological, clinical, and biological evidence. It finds that while no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines. In addition, the evidence shows that vaccines do not cause several conditions. For example, the MMR vaccine is not associated with autism or childhood diabetes. Also, the DTaP vaccine is not associated with diabetes and the influenza vaccine given as a shot does not exacerbate asthma. Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors.

• Author : Larry Olmsted
• Publisher : Algonquin Books
• Release Date : 2017-10-03
• Total pages : 353
• ISBN : 9781616207410
• File Size : 46,9 Mb
• Total Download : 376
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Download Real Food/Fake Food in PDF, Epub, and Kindle

“Olmsted makes you insanely hungry and steaming mad--a must-read for anyone who cares deeply about the safety of our food and the welfare of our planet.” —Steven Raichlen, author of the Barbecue! Bible series “The world is full of delicious, lovingly crafted foods that embody the terrain, weather, and culture of their origins. Unfortunately, it’s also full of brazen impostors. In this entertaining and important book, Olmsted helps us fall in love with the real stuff and steer clear of the fraudsters.” —Kirk Kardashian, author of Milk Money: Cash, Cows, and the Death of the American Dairy Farm You’ve seen the headlines: Parmesan cheese made from wood pulp. Lobster rolls containing no lobster at all. Extra-virgin olive oil that isn’t. So many fake foods are in our supermarkets, our restaurants, and our kitchen cabinets that it’s hard to know what we’re eating anymore. In Real Food / Fake Food, award-winning journalist Larry Olmsted convinces us why real food matters and empowers consumers to make smarter choices. Olmsted brings readers into the unregulated food industry, revealing the shocking deception that extends from high-end foods like olive oil, wine, and Kobe beef to everyday staples such as coffee, honey, juice, and cheese. It’s a massive bait and switch in which counterfeiting is rampant and in which the consumer ultimately pays the price. But Olmsted does more than show us what foods to avoid. A bona fide gourmand, he travels to the sources of the real stuff to help us recognize what to look for, eat, and savor: genuine Parmigiano-Reggiano from Italy, fresh-caught grouper from Florida, authentic port from Portugal. Real foods that are grown, raised, produced, and prepared with care by masters of their craft. Part cautionary tale, part culinary crusade, Real Food / Fake Food is addictively readable, mouthwateringly enjoyable, and utterly relevant.

• Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Pain Management and Regulatory Strategies to Address Prescription Opioid Abuse
• Publisher : National Academies Press
• Release Date : 2017-09-28
• Total pages : 482
• ISBN : 9780309459570
• File Size : 35,9 Mb
• Total Download : 253
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Download Pain Management and the Opioid Epidemic in PDF, Epub, and Kindle

Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

• Author : Leanne Brown
• Publisher : Workman Publishing Company
• Release Date : 2015-07-14
• Total pages : 208
• ISBN : 9780761184171
• File Size : 53,8 Mb
• Total Download : 162
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Download Good and Cheap in PDF, Epub, and Kindle

A perfect and irresistible idea: A cookbook filled with delicious, healthful recipes created for everyone on a tight budget. While studying food policy as a master’s candidate at NYU, Leanne Brown asked a simple yet critical question: How well can a person eat on the $4 a day given by SNAP, the U.S. government’s Supplemental Nutrition Assistance Program informally known as food stamps? The answer is surprisingly well: Broiled Tilapia with Lime, Spicy Pulled Pork, Green Chile and Cheddar Quesadillas, Vegetable Jambalaya, Beet and Chickpea Salad—even desserts like Coconut Chocolate Cookies and Peach Coffee Cake. In addition to creating nutritious recipes that maximize every ingredient and use economical cooking methods, Ms. Brown gives tips on shopping; on creating pantry basics; on mastering certain staples—pizza dough, flour tortillas—and saucy extras that make everything taste better, like spice oil and tzatziki; and how to make fundamentally smart, healthful food choices. The idea for Good and Cheap is already proving itself. The author launched a Kickstarter campaign to self-publish and fund the buy one/give one model. Hundreds of thousands of viewers watched her video and donated $145,000, and national media are paying attention. Even high-profile chefs and food writers have taken note—like Mark Bittman, who retweeted the link to the campaign; Francis Lam, who called it “Terrific!”; and Michael Pollan, who cited it as a “cool kickstarter.” In the same way that TOMS turned inexpensive, stylish shoes into a larger do-good movement, Good and Cheap is poised to become a cookbook that every food lover with a conscience will embrace.

• Author : Yehuda Shoenfeld,D. Harats,G. Wick
• Publisher : Elsevier
• Release Date : 2001-02-27
• Total pages : 396
• ISBN : 0080527655
• File Size : 45,8 Mb
• Total Download : 877
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Download Atherosclerosis and Autoimmunity in PDF, Epub, and Kindle

Presenting further studies in the prevention and treatment of coronary artery disease, this book brings together the knowledge accrued in the past decade concerning the role of immunity in the initiation and perpetuation of atherosclerosis. A strong group of international contributors summarize the diverse aspects of the interrelationship between the immune system and atherosclerosis.

• Author : Michael Selzer,Stephanie Clarke,Leonardo Cohen,Gert Kwakkel,Robert Miller
• Publisher : Cambridge University Press
• Release Date : 2014-04-24
• Total pages : 693
• ISBN : 9781107011670
• File Size : 10,9 Mb
• Total Download : 411
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Download Textbook of Neural Repair and Rehabilitation in PDF, Epub, and Kindle

Volume 1 of the Textbook of Neural Repair and Rehabilitation covers the basic sciences relevant to recovery of function following injury to the nervous system.

• Author : Anonim
• Publisher : Elsevier
• Release Date : 2022-04-22
• Total pages : 2112
• ISBN : 012818731X
• File Size : 51,6 Mb
• Total Download : 619
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Download Encyclopedia of Infection and Immunity in PDF, Epub, and Kindle

Encyclopedia of Infection and Immunity provides new insights into the interactions between bacteria, fungi, parasites and their hosts. Specific areas of interest include host cellular and immune response to microbes, molecular mechanisms of action of beneficial microbes or host-associated microbial communities, microbial pathogenesis, virulence factors, experimental models of infection, host resistance or susceptibility, and the generation of innate and adaptive immune responses. Comprised of over 200 chapters written and edited by leading experts in the field, this book will serve as a key resource for students, researchers, academics and industry practitioners in the fields of microbiology, immunology, and infectious diseases. More than 100 years after Robert Koch and Louis Pasteur established the microbial etiology of communicable diseases, the field of microbiology is experiencing a second period of rapid growth and expansion, driven by the realization that changes in host-associated microbial communities might be at the root of a broad spectrum of noncommunicable human diseases. These advances follow on the heels of recent progress in high-throughput sequencing technology, which has provided a wealth of information on the human microbiome and its physiological potential. Offers a contemporary review of current infection and immunity research, and insights into the future direction of the field Meticulously researched and cross-referenced to allow students, researchers and professionals to find relevant information quickly and easily Includes chapters written by academics and practitioners from various fields and regions, ensuring that the knowledge within is easily understood by, and applicable to, a large audience

• Author : Henry J. Kaminski
• Publisher : Springer Science & Business Media
• Release Date : 2002-10-03
• Total pages : 396
• ISBN : 9781592593415
• File Size : 35,7 Mb
• Total Download : 418
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Download Myasthenia Gravis and Related Disorders in PDF, Epub, and Kindle

An international panel of expert clinicians and leading scientists comprehensively review the clinical and basic science of this disease and its relatives, including acquired neuromytonia and Lambert-Eaton syndrome. For the clinician, the book describes the wide range of signs and symptoms that make these diseases difficult to diagnose, review in depth the available diagnostic methods and their limitations, offer practical treatment recommendations based on years of experience, and discuss several promising treatments now emerging. For the basic scientist, the text illuminates neuromuscular structure and function, describes in detail the acetylcholine receptor (the central target of pathology in myasthenia gravis), and illuminates the autoimmune pathogenesis.

• Author : Bruno Latour,Steve Woolgar
• Publisher : Princeton University Press
• Release Date : 2013-04-04
• Total pages : 296
• ISBN : 9781400820412
• File Size : 15,9 Mb
• Total Download : 884
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Download Laboratory Life in PDF, Epub, and Kindle

This highly original work presents laboratory science in a deliberately skeptical way: as an anthropological approach to the culture of the scientist. Drawing on recent work in literary criticism, the authors study how the social world of the laboratory produces papers and other "texts,"' and how the scientific vision of reality becomes that set of statements considered, for the time being, too expensive to change. The book is based on field work done by Bruno Latour in Roger Guillemin's laboratory at the Salk Institute and provides an important link between the sociology of modern sciences and laboratory studies in the history of science.

• Author : Leslie Neal-Boylan
• Publisher : John Wiley & Sons
• Release Date : 2011-11-28
• Total pages : 432
• ISBN : 9781118277850
• File Size : 52,7 Mb
• Total Download : 756
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Download Clinical Case Studies for the Family Nurse Practitioner in PDF, Epub, and Kindle

Clinical Case Studies for the Family Nurse Practitioneris a key resource for advanced practice nurses and graduatestudents seeking to test their skills in assessing, diagnosing, andmanaging cases in family and primary care. Composed of morethan 70 cases ranging from common to unique, the book compilesyears of experience from experts in the field. It is organizedchronologically, presenting cases from neonatal to geriatric carein a standard approach built on the SOAP format. Thisincludes differential diagnosis and a series of critical thinkingquestions ideal for self-assessment or classroom use.