The Artificial Pancreas

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• Author : Ricardo S. Sánchez-Peña,Daniel R. Cherñavvsky
• Publisher : Academic Press
• Release Date : 2019-04-15
• Total pages : 0
• ISBN : 0128156554
• File Size : 32,7 Mb
• Total Download : 261
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Download The Artificial Pancreas in PDF, Epub, and Kindle

The Artificial Pancreas: Current Situation and Future Directions presents research on the top issues relating to the artificial pancreas (AP) and its application to diabetes. AP is a newer form of treatment to accurately and efficiently inject insulin, thereby significantly improving the patient's quality of life. By connecting a continuous glucose monitor (CGM) to a continuous subcutaneous insulin infusion using a control algorithm, AP delivers and regulates the most accurate amount of insulin to maintain normal glycemic values. Featured chapters in this book are written by world leaders in AP research, thus providing readers with the latest studies and results.

• Author : Ricardo S. Sánchez-Peña,Daniel R. Cherñavvsky
• Publisher : Academic Press
• Release Date : 2019-04-15
• Total pages : 306
• ISBN : 9780128156568
• File Size : 15,8 Mb
• Total Download : 529
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Download The Artificial Pancreas in PDF, Epub, and Kindle

The Artificial Pancreas: Current Situation and Future Directions presents research on the top issues relating to the artificial pancreas (AP) and its application to diabetes. AP is a newer form of treatment to accurately and efficiently inject insulin, thereby significantly improving the patient’s quality of life. By connecting a continuous glucose monitor (CGM) to a continuous subcutaneous insulin infusion using a control algorithm, AP delivers and regulates the most accurate amount of insulin to maintain normal glycemic values. Featured chapters in this book are written by world leaders in AP research, thus providing readers with the latest studies and results. Focuses on Type 1 Diabetes Mellitus (T1DM) that is primarily found in children and typically treated by means of a syringe or insulin pump Features research and results from top academic experimental groups, and from universities such as Harvard (USA), the University of Virginia (USA), the University of Padova (Italy), the University of Montpellier (France), and the Buenos Aires Institute of Technology (Argentina) Discusses clinical trials of AP from around the world, including the United States, the EU, Latin America, and Israel

• Author : Ali Cinar,Kamuran Turksoy
• Publisher : Springer
• Release Date : 2018-03-01
• Total pages : 119
• ISBN : 9783319722450
• File Size : 34,9 Mb
• Total Download : 597
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Download Advances in Artificial Pancreas Systems in PDF, Epub, and Kindle

This brief introduces recursive modeling techniques that take account of variations in blood glucose concentration within and between individuals. It describes their use in developing multivariable models in early-warning systems for hypo- and hyperglycemia; these models are more accurate than those solely reliant on glucose and insulin concentrations because they can accommodate other relevant influences like physical activity, stress and sleep. Such factors also contribute to the accuracy of the adaptive control systems present in the artificial pancreas which is the focus of the brief, as their presence is indicated before they have an apparent effect on the glucose concentration and so can be more easily compensated. The adaptive controller is based on generalized predictive control techniques and also includes rules for changing controller parameters or structure based on the values of physiological variables. Simulation studies and clinical studies are reported to illustrate the performance of the techniques presented.

• Author : Dana M Lewis
• Publisher : Independently Published
• Release Date : 2019-05-31
• Total pages : 164
• ISBN : 1797763695
• File Size : 29,9 Mb
• Total Download : 312
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Download Automated Insulin Delivery in PDF, Epub, and Kindle

Automated insulin delivery goes by many names: hybrid or full closed loop; artificial pancreas system (APS); "looping" and more. They are not all the same, though. You have choices, ranging from the type of pump body and CGM you want to use, to the algorithm and controller, to the interoperability and remote monitoring options, and more. Like switching from multiple daily injections to an insulin pump, switching from manual diabetes to automated insulin delivery has a learning curve. It's certainly one you can tackle. After all, you're already tackling type 1 diabetes! You already have the base knowledge and experience you need to succeed with a closed loop system, if it's right for you. But you might be wondering how to get ahead of your learning curve before you start or even choose an APS, or you've started and want to dig even deeper into optimizing how an automated insulin delivery system fits into your lifestyle. This book was written for you! It leverages the collective knowledge of the early adopters of do-it-yourself and commercial systems from the past five years and packages it into easy, understandable guides and lessons learned.In this book, you'll find new analogies to help you understand - and explain - this new method of diabetes management, and tips on how to communicate with your healthcare provider(s) about it. You'll see stories and examples from real families and individuals living with type 1 diabetes and how they benefit from artificial pancreas systems, and why they chose and continue to choose to use them. You'll be empowered to understand the basic components of artificial pancreas systems, how they work, and what questions to ask as you peruse your choices now and in the future. This book also includes a foreword by Aaron Kowalski, President and CEO of JDRF, and co-founder of the JDRF Artificial Pancreas Project. "I will immediately recommend this book not just to people looking to use a DIY closed loop system, but also to anybody looking to improve their grasp on the management of type 1 diabetes, whether patient, caregiver, or healthcare provider." - Aaron Neinstein, MD (Endocrinologist, UCSF)

• Author : United States. Congress. Senate. Committee on Homeland Security and Governmental Affairs
• Publisher : Unknown
• Release Date : 2007
• Total pages : 68
• ISBN : STANFORD:36105050461099
• File Size : 53,5 Mb
• Total Download : 807
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Download The Potential of an Artificial Pancreas in PDF, Epub, and Kindle

PDF book entitled The Potential of an Artificial Pancreas written by United States. Congress. Senate. Committee on Homeland Security and Governmental Affairs and published by Unknown which was released on 2007 with total hardcover pages 68, the book become popular and critical acclaim.

• Author : Chase
• Publisher : Unknown
• Release Date : 2016
• Total pages : 162
• ISBN : 0000490016
• File Size : 46,5 Mb
• Total Download : 297
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Download Understanding Insulin Pumps, Continuous Glucose Monitors and the Artificial Pancreas in PDF, Epub, and Kindle

PDF book entitled Understanding Insulin Pumps, Continuous Glucose Monitors and the Artificial Pancreas written by Chase and published by Unknown which was released on 2016 with total hardcover pages 162, the book become popular and critical acclaim.

• Author : H. Peter Chase,Laurel Messer
• Publisher : Unknown
• Release Date : 2016
• Total pages : 178
• ISBN : 0983265070
• File Size : 46,9 Mb
• Total Download : 569
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Download Understanding Insulin Pumps, Continuous Glucose Monitors, and the Artificial Pancreas in PDF, Epub, and Kindle

PDF book entitled Understanding Insulin Pumps, Continuous Glucose Monitors, and the Artificial Pancreas written by H. Peter Chase,Laurel Messer and published by Unknown which was released on 2016 with total hardcover pages 178, the book become popular and critical acclaim.

• Author : D. Bruttomesso,G. Grassi
• Publisher : Karger Medical and Scientific Publishers
• Release Date : 2014-11-17
• Total pages : 272
• ISBN : 9783318023374
• File Size : 10,5 Mb
• Total Download : 332
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Download Technological Advances in the Treatment of Type 1 Diabetes in PDF, Epub, and Kindle

The current epidemic of diabetes, obesity and related disorders is a driving force in the development of new technologies. Technological advances offer great new opportunities for the treatment of these chronic diseases. This review presents an update of developments that promise to revolutionize the treatment of diabetes. It examines hospital and outpatient care, intensive insulin therapy, blood glucose monitoring and innovative steps towards the construction of an artificial pancreas. Providing a comprehensive overview on the latest advances, this volume of Frontiers in Diabetes will be of particular interest to all healthcare providers involved in the daily management of patients with diabetes or related diseases.

• Author : Yvonne Ho
• Publisher : Unknown
• Release Date : 2019
• Total pages : 229
• ISBN : 9811324034
• File Size : 55,5 Mb
• Total Download : 721
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Download Patient-specific Controller for an Implantable Artificial Pancreas in PDF, Epub, and Kindle

"The thesis focuses on the control of blood glucose devices and design of implantable devices, and offers valuable insights on diabetes mellitus and related physiology and treatments. Diabetes mellitus is a widespread chronic disease in the modern world that affects millions of people around the globe. In Singapore, one in ten of the population has diabetes, and the severity of the problem has prompted the country's prime minister to talk about the disease at the National Day Rally in 2017. Designing an artificial pancreas that can provide effective blood glucose control for individuals with diabetes is one of the most challenging engineering problems. The author reports on research into the development of an implantable artificial pancreas that can regulate blood glucose levels by delivering appropriate dosages of insulin when necessary. By sensing blood glucose and injecting insulin directly into the vein, the implantable device aims to remove delays that occur with subcutaneous blood glucose sensing and insulin delivery. Preliminary in-vitro and in-vivo experimental results suggest that the implantable device for blood glucose control could be a clinically viable alternative to pancreas transplant."--

• Author : Ernst F. Pfeiffer,Wolfgang Kerner
• Publisher : Unknown
• Release Date : 1981
• Total pages : 35
• ISBN : OCLC:551882811
• File Size : 13,6 Mb
• Total Download : 174
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Download The Artificial Pancreas in PDF, Epub, and Kindle

PDF book entitled The Artificial Pancreas written by Ernst F. Pfeiffer,Wolfgang Kerner and published by Unknown which was released on 1981 with total hardcover pages 35, the book become popular and critical acclaim.

• Author : Kim Vanessa Enders
• Publisher : GRIN Verlag
• Release Date : 2022-05-09
• Total pages : 68
• ISBN : 9783346640499
• File Size : 11,9 Mb
• Total Download : 428
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Download Cost-effectiveness of hybrid closed-loop artificial pancreas systems in patients with type 1 diabetes in PDF, Epub, and Kindle

Master's Thesis from the year 2022 in the subject Health - Digital Health Management, grade: 1.0, University College London, language: English, abstract: This paper is about the cost-effectiveness of hybrid closed-loop artificial pancreas systems in patients with type 1 diabetes. Advances in diabetes technology over the past decade have culminated in the commercialization of hybrid closed-loop (HCL) artificial pancreas systems, alleviating the onus of self-management in type 1 diabetes (T1D). Clinical effectiveness benefits over conventional systems are well-documented. However, no systematic review has been performed on the cost-effectiveness of HCL systems, even if health economic assessments are integral to guide policy decisions. To perform a systematic review, critical analysis, and narrative synthesis of available economic evaluations of HCL systems for T1D patients and upcoming cost-effectiveness studies within the research pipeline. A systematic search was conducted following the PRISMA 2020 guidelines in MEDLINE, Embase, and CENTRAL via Ovid in October 2021. A review of trial registries and grey literature, as well as reference list and forward citation search, complemented the search. Predefined eligibility criteria were used. Retrieved studies underwent CHEERS-based quality assessment. Data were subsequently extracted via a standardized data extraction form. Results were presented through narrative synthesis, dominance ranking framework, and display of standardized ICERs (in 2021 GBP) in a cost-effectiveness plane. Of the 213 records retrieved via systematic review and 331 identified through other search methods, 8 were included in the review and 11 in the research pipeline. Overall, included studies demonstrated good quality. Standardized ICERs ranged from 5,688 to 30,293 GBP per QALY gained. Limitations of included evidence were discussed in detail and contain lack of long-term effectiveness data and inter-system comparisons, as well as possible conflicts of interest. Overall results suggest cost-effectiveness for HCL systems compared to current treatment standards such as CSII, CGM, and SAP. Additional high-quality, large scale, and long-term economic research is required to assess health economic outcomes for HCL technology in clinical practice. This thesis provides fundamental starting points in the research pipeline as a basis of further research.

• Author : Jort Kropff
• Publisher : Unknown
• Release Date : 2017
• Total pages : 231
• ISBN : 9463321446
• File Size : 45,6 Mb
• Total Download : 147
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Download The Artificial Pancreas in PDF, Epub, and Kindle

"In this thesis we investigated the efficacy of real-life use of an artificial pancreas starting with use of these systems in a hotel setting and finally 24/7 long-term use at home. We investigated the accuracy of continuous glucose monitoring (CGM) systems that act as input for the artificial pancreas or for use in combination with an insulin pump or pen. Since CGM data are used for insulin-dosing, their accuracy and reliability are essential. Our research on two commonly used CGM systems indicates that measurement accuracy differs to an extent that is clinically relevant. We show that a novel category of implantable CGM can perform safely and accurately over a lifetime of up to 180 days whereas current CGM have a lifetime of 7 days. Innovations as these provide opportunities for use in artificial pancreas systems. Our results indicate that an artificial pancreas can be used safely and effectively not only during night-time in a hotel environment but also during long term day and night use. The artificial pancreas improves glycaemic control including a reduction of time spent in hypoglycaemia, hyperglycaemia and HbA1c compared to open-loop use of a sensor and pump. Use of an adaptive, self-learning, artificial pancreas further improves glycaemic control during night-time. Participants appreciate the positive effects on glucose regulation but technical errors limit their appreciation for the current system. We conclude that the artificial pancreas facilitates good glucose control and holds the promise to alleviate the disease burden improving the life of a person with diabetes substantially."--Samenvatting auteur.

• Author : P. Drouin,Gérard Debry,L. Méjean
• Publisher : Unknown
• Release Date : 1980
• Total pages : 253
• ISBN : 2704003548
• File Size : 52,8 Mb
• Total Download : 686
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Download Artificial Pancreas in PDF, Epub, and Kindle

PDF book entitled Artificial Pancreas written by P. Drouin,Gérard Debry,L. Méjean and published by Unknown which was released on 1980 with total hardcover pages 253, the book become popular and critical acclaim.

• Author : Martin Tauschmann
• Publisher : Unknown
• Release Date : 2019
• Total pages : 229
• ISBN : OCLC:1091681003
• File Size : 54,7 Mb
• Total Download : 416
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Download The Artificial Pancreas in Children and Adolescents with Type 1 Diabetes in PDF, Epub, and Kindle

PDF book entitled The Artificial Pancreas in Children and Adolescents with Type 1 Diabetes written by Martin Tauschmann and published by Unknown which was released on 2019 with total hardcover pages 229, the book become popular and critical acclaim.

• Author : K. Federlin
• Publisher : Unknown
• Release Date : 1982
• Total pages : 332
• ISBN : UOM:39015006003639
• File Size : 44,6 Mb
• Total Download : 327
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Download Islet-pancreas-transplantation and Artificial Pancreas in PDF, Epub, and Kindle

PDF book entitled Islet-pancreas-transplantation and Artificial Pancreas written by K. Federlin and published by Unknown which was released on 1982 with total hardcover pages 332, the book become popular and critical acclaim.

• Author : Anirudh Nath,Rajeeb Dey,Valentina Emilia Balas
• Publisher : Academic Press
• Release Date : 2022-08-13
• Total pages : 164
• ISBN : 9780323907774
• File Size : 42,5 Mb
• Total Download : 303
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Download Nonlinear Control for Blood Glucose Regulation of Diabetic Patients: An LMI Approach in PDF, Epub, and Kindle

Nonlinear Control for Blood Glucose Regulation of Diabetic Patients: An LMI-Based Approach exposes readers to the various existing mathematical models that define the dynamics of glucose-insulin for Type 1 diabetes patients. After providing insights into the mathematical model of patients, the authors discuss the need and emergence of new control techniques that can lead to further development of an artificial pancreas. The book presents various nonlinear control techniques to address the challenges that Type 1 diabetic patients face in maintaining their blood glucose level in the safe range (70-180 mg/dl). The closed-loop solution provided by the artificial pancreas depends mainly on the effectiveness of the control algorithm, which acts as the brain of the system. APS control algorithms require a mathematical model of the gluco-regulatory system of the T1D patients for their design. Since the gluco-regulatory system is inherently nonlinear and largely affected by external disturbances and parametric uncertainty, developing an accurate model is very difficult. Presents control-oriented modeling of the gluco-regulatory system of Type 1 diabetic patients using input-output data Demonstrates the design of a robust insulin delivery mechanism utilizing state estimation information with parametric uncertainties and exogenous disturbance in the framework of Linear Matrix Inequality (LMI) Introduces readers to the relevance and effectiveness of powerful nonlinear controllers for the Artificial Pancreas Provides the first book on LMI-based nonlinear control techniques for the Artificial Pancreas

• Author : Arianne Cornelia van Bon
• Publisher : Unknown
• Release Date : 2013
• Total pages : 160
• ISBN : 9090279814
• File Size : 51,6 Mb
• Total Download : 261
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Download The Artificial Pancreas, a Challenge to Research in PDF, Epub, and Kindle

PDF book entitled The Artificial Pancreas, a Challenge to Research written by Arianne Cornelia van Bon and published by Unknown which was released on 2013 with total hardcover pages 160, the book become popular and critical acclaim.

• Author : Kenneth N. Matsumura,William L. Hamilton
• Publisher : Unknown
• Release Date : 1978
• Total pages : 100
• ISBN : UOM:39015000895899
• File Size : 41,9 Mb
• Total Download : 669
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Download After Fifteen Years in PDF, Epub, and Kindle

PDF book entitled After Fifteen Years written by Kenneth N. Matsumura,William L. Hamilton and published by Unknown which was released on 1978 with total hardcover pages 100, the book become popular and critical acclaim.

• Author : Chiara Fabris,Boris Kovatchev
• Publisher : Academic Press
• Release Date : 2020-06-02
• Total pages : 384
• ISBN : 9780128168844
• File Size : 46,5 Mb
• Total Download : 876
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Download Glucose Monitoring Devices in PDF, Epub, and Kindle

Glucose Monitoring Devices: Measuring Blood Glucose to Manage and Control Diabetes presents the state-of-the-art regarding glucose monitoring devices and the clinical use of monitoring data for the improvement of diabetes management and control. Chapters cover the two most common approaches to glucose monitoring–self-monitoring blood glucose and continuous glucose monitoring–discussing their components, accuracy, the impact of use on quality of glycemic control as documented by landmark clinical trials, and mathematical approaches. Other sections cover how data obtained from these monitoring devices is deployed within diabetes management systems and new approaches to glucose monitoring. This book provides a comprehensive treatment on glucose monitoring devices not otherwise found in a single manuscript. Its comprehensive variety of topics makes it an excellent reference book for doctoral and postdoctoral students working in the field of diabetes technology, both in academia and industry. Presents a comprehensive approach that spans self-monitoring blood glucose devices, the use of continuous monitoring in the artificial pancreas, and intraperitoneal glucose sensing Provides a high-level descriptions of devices, as well as detailed mathematical descriptions of methods and techniques Written by experts in the field with vast experience in the field of diabetes and diabetes technology

• Author : Yves Reznik
• Publisher : Springer
• Release Date : 2019-01-31
• Total pages : 117
• ISBN : 9783319981192
• File Size : 39,6 Mb
• Total Download : 655
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Download Handbook of Diabetes Technology in PDF, Epub, and Kindle

This book covers the main fields of diabetes management through applied technologies. The different chapters include insulin therapy through basic insulin injection therapy, external and implantable insulin pumps and the more recent approaches such as sensor augmented pumps and close-loop systems. Islet transplantation is also described through its technical aspects and clinical evaluation. Glucose measurement through blood glucose meters and continuous glucose monitoring systems are comprehensively explained. Educational tools including videogames and software dedicated to diabetes management are depicted. Lastly, Telemedicine systems devoted to data transmission, telemonitoring and decision support systems are described and their use for supporting health systems are summarized. This book will help professionals involved in diabetes management understanding the contribution of diabetes technologies for promoting the optimization of glucose control and monitoring. This volume will be helpful in current clinical practice for diabetes management and also beneficial to students.

• Author : Eleni I. Georga,Dimitrios I Fotiadis,Stelios K. Tigas
• Publisher : Academic Press
• Release Date : 2017-12-11
• Total pages : 252
• ISBN : 9780128051467
• File Size : 36,9 Mb
• Total Download : 781
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Download Personalized Predictive Modeling in Type 1 Diabetes in PDF, Epub, and Kindle

Personalized Predictive Modeling in Diabetes features state-of-the-art methodologies and algorithmic approaches which have been applied to predictive modeling of glucose concentration, ranging from simple autoregressive models of the CGM time series to multivariate nonlinear regression techniques of machine learning. Developments in the field have been analyzed with respect to: (i) feature set (univariate or multivariate), (ii) regression technique (linear or non-linear), (iii) learning mechanism (batch or sequential), (iv) development and testing procedure and (v) scaling properties. In addition, simulation models of meal-derived glucose absorption and insulin dynamics and kinetics are covered, as an integral part of glucose predictive models. This book will help engineers and clinicians to: select a regression technique which can capture both linear and non-linear dynamics in glucose metabolism in diabetes, and which exhibits good generalization performance under stationary and non-stationary conditions; ensure the scalability of the optimization algorithm (learning mechanism) with respect to the size of the dataset, provided that multiple days of patient monitoring are needed to obtain a reliable predictive model; select a features set which efficiently represents both spatial and temporal dependencies between the input variables and the glucose concentration; select simulation models of subcutaneous insulin absorption and meal absorption; identify an appropriate validation procedure, and identify realistic performance measures. Describes fundamentals of modeling techniques as applied to glucose control Covers model selection process and model validation Offers computer code on a companion website to show implementation of models and algorithms Features the latest developments in the field of diabetes predictive modeling