Sex Differences In Cardiovascular Physiology And Pathophysiology

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Sex Differences in Cardiovascular Physiology and Pathophysiology

Sex Differences in Cardiovascular Physiology and Pathophysiology
  • Author : Babbette LaMarca,Barbara T. Alexander
  • Publisher : Academic Press
  • Release Date : 2019-04-09
  • Total pages : 392
  • ISBN : 9780128131985
  • File Size : 44,6 Mb
  • Total Download : 629
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Sex Differences in Cardiovascular Physiology and Pathophysiology is a comprehensive look into the often overlooked and underappreciated fundamental sex differences between men and women and how those differences affect the cardiovascular system. It covers cardiovascular function, anatomy, cell signaling and the development of pathology. With contributions from world-renowned research investigators, this up-to-date reference compiles critical knowledge on cardiovascular sex differences, providing researchers and clinicians with a better understanding of the diagnosis, prevention and treatment of cardiovascular diseases in both men and women. Identifies the fundamental sex differences in the physiology and pathophysiology of the cardiovascular system Describes cell signaling pathways involved in sex-associated cardiovascular function and diseases Puts the sex differences in cardiovascular diseases in the forefront to improve cardiovascular prognoses

Sex Differences in Physiology

Sex Differences in Physiology
  • Author : Gretchen Neigh,Megan Mitzelfelt
  • Publisher : Academic Press
  • Release Date : 2016-05-10
  • Total pages : 236
  • ISBN : 9780128026083
  • File Size : 16,8 Mb
  • Total Download : 762
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Sex Differences in Physiology is an all-encompassing reference that details basic science research into sex differences in all physiological fields. It includes scientific discoveries concerning sex differences in cardiovascular, respiratory, renal, gastrointestinal, and musculoskeletal physiology. In addition, coverage of the development, endocrinology, neurophysiology, immunity, and metabolism is included, making this important reference a resource that will meet the needs of investigators interested in incorporating sex differences into their research programs, while also providing clinicians with the basis for providing the best sex-based medical treatment options available. Provides a sweeping, organ-by-organ review of currently observed sex differences in animal models and human disease Explains how sex differences influence physiology and disease Provides the critical knowledge on sex differences for better understanding of prevention and treatment of diseases

Gender Differences in the Pathogenesis and Management of Heart Disease

Gender Differences in the Pathogenesis and Management of Heart Disease
  • Author : Jawahar L. Mehta,Jean McSweeney
  • Publisher : Springer
  • Release Date : 2018-03-02
  • Total pages : 361
  • ISBN : 9783319711355
  • File Size : 43,9 Mb
  • Total Download : 227
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This book reviews all aspects of the diagnosis and management of heart disease in women, covering areas such as gender differences in metabolic syndrome, hypertension and atherogenesis. Gender differences in cardiovascular diseases are widespread, but while gender medicine takes into account the effects of sex and gender on the health of women and men, traditionally, women have been underrepresented in cardiovascular clinical trials, in management of different cardiac diseases and drug use. Gender Differences in the Pathogenesis and Management of Heart Disease deals with the gender-specific differences in cardiac physiology and diseases and brings into perspective the critical significance of gender in management of cardiovascular disease presentations and management. As such it is of enormous use to all clinical staff who manage women with cardiovascular disease.

Sex Differences in Heart Disease

Sex Differences in Heart Disease
  • Author : Bohuslav Ostadal,Naranjan S. Dhalla
  • Publisher : Springer Nature
  • Release Date : 2020-11-15
  • Total pages : 284
  • ISBN : 9783030586775
  • File Size : 36,8 Mb
  • Total Download : 850
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Cardiovascular diseases are the leading cause of mortality in men and women. Unfortunately, women have traditionally been excluded from clinical trials, and female animals have been used less or sex was not reported in basic research studies. Until recently, consideration of both sexes was not required in clinical and preclinical studies focusing on cardiovascular diseases. However, the number of clinical and experimental papers dealing with sex differences and heart disease significantly increases during the last years. This trend is obviously the result of at least two facts: the number of examples of different behavior of the male and female heart under physiological and pathological conditions is steadily increasing and there were controversial reports on the beneficial and adverse effect of hormonal replacement therapy. Detailed molecular and cellular mechanisms of these differences are still unknown but one is clear already today: sex differences are so important that they should be considered by the selection of optimum diagnostic and therapeutic procedures in clinical practice. The book presents 16 manuscripts on sex differences of heart disease, as developed by several investigators; the volume is organized in four parts. Part I, dealing with sex differences in cardiac ischemic injury, includes 5 chapters on experimental aspects of cardiac ischemia/reperfusion injury, the role of testosterone, and clinical aspects of ischemic heart disease. Part II is devoted to sex differences in heart failure and includes four chapters. Discussion in this part of the book is centered around the sex differences in heart failure due to volume overload. Part III of this volume includes four papers on risk factors of cardiovascular diseases, namely hypertension and obesity, and, finally, three chapters in part IV deal with sex differences of cardiac mitochondria under different pathological conditions. We believe this book will be very useful for cardiovascular scientists, graduate students, postdoctoral fellows and other health professionals.

Sex-Specific Analysis of Cardiovascular Function

Sex-Specific Analysis of Cardiovascular Function
  • Author : Peter L. M. Kerkhof,Virginia M. Miller
  • Publisher : Springer
  • Release Date : 2018-07-26
  • Total pages : 725
  • ISBN : 9783319779324
  • File Size : 53,6 Mb
  • Total Download : 885
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This book gathers together contributions from internationally renowned authors in the field of cardiovascular systems and provides crucial insight into the importance of sex- and gender-concepts during the analysis of patient data. This innovative title is the first to offer the elements necessary to consider sex-related properties in both clinical and basic studies regarding the heart and circulation on multiscale levels (i.e. molecular, cellular, electrophysiologically, neuroendocrine, immunoregulatory, organ, allometric, and modeling). Observed differences at (ultra)cellular and organ level are quantified, with focus on clinical relevance and implications for diagnosis and patient management. Since the cardiovascular system is of vital importance for all tissues, Sex-Specific Analysis of Cardiovascular Function is an essential source of information for clinicians, biologists, and biomedical investigators. The wide spectrum of differences described in this book will also act as an eye-opener and serve as a handbook for students, teachers, scientists and practitioners.

Sex and Gender Differences in Cardiovascular-Renal Diseases and Hypertension

Sex and Gender Differences in Cardiovascular-Renal Diseases and Hypertension
  • Author : Jane Reckelhoff
  • Publisher : Biota Publishing
  • Release Date : 2014-11-01
  • Total pages : 99
  • ISBN : 9781615045792
  • File Size : 51,6 Mb
  • Total Download : 684
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Many of the mechanisms responsible for cardiovascular disease and hypertension are well known, and gender is an independent risk factor in many cohorts. How gender contributes to cardiovascular disease has not been completely elucidated. Even in normotensive populations, blood pressure is higher in men than women, although why this occurs is unclear. While both men and women suffer from high incidences of cardiovascular disease, women are typically protected against cardiovascular disease until after menopause, so that on average they are about 10 years older than men when these diseases develop, making aging a confounding problem contributing to increased morbidity. Because hypertension is one of the leading causes of cardiovascular disease in both men and women, this review will focus on hypertension, and the mechanisms that have been found to play a role in mediating blood pressure control and how they differ in men and women.

Principles of Sex-based Differences in Physiology

Principles of Sex-based Differences in Physiology
  • Author : Virginia L. Miller,Virginia M. Miller,Meredith Hay
  • Publisher : Gulf Professional Publishing
  • Release Date : 2004
  • Total pages : 356
  • ISBN : 044451497X
  • File Size : 31,9 Mb
  • Total Download : 688
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Differences in physiology between men and women extend far beyond differences in reproductive functions. Medical literature abounds in descriptions of differences in prevalence, symptoms and severity of diseases between men and women including heart attack, rheumatic diseases, gastrointestinal disease and osteoporosis. Much of the information is descriptive rather than mechanistic and scattered throughout a variety of books, review articles and original papers. This book provides a single source that summarizes current basic mechanisms of gene/hormone interactions and their subsequent impact on physiological functions. It is an ideal source material to be used in training the next generation of physician/scientists who will develop a more individualized approach to prevention, diagnosis and therapeutic medical practice.

Sex and Cardiac Electrophysiology

Sex and Cardiac Electrophysiology
  • Author : Marek Malik
  • Publisher : Academic Press
  • Release Date : 2020-07-11
  • Total pages : 1032
  • ISBN : 9780128177297
  • File Size : 38,7 Mb
  • Total Download : 492
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Sex and Cardiac Electrophysiology: Differences in Cardiac Electrical Disorders Between Men and Women is a comprehensive investigation into all aspects of sex differences in cardiac electrophysiology. As there are substantial differences between female and male patients in physiology, pathology triggering factors, disease progression, clinical approaches and treatment outcome, this book provides a comprehensive examination. In cardiology, the differences between women and men are more recognized, hence this title summarizes these important differences, providing the essential information needed for clinical specialists and researchers involved in the design and implementation of clinical studies. Explores topics ranging from the physiologic differences between women and men to the differences in clinical handling of arrhythmic disorders between female and male patients Provides sex differences in cardiac electrophysiology in separate chapters Covers the sex differences of cardiac electrical disorders, providing insights beyond cardiac metabolic syndrome, hypertension, atherogenesis and heart failure

Principles of Gender-Specific Medicine

Principles of Gender-Specific Medicine
  • Author : Marianne J. Legato
  • Publisher : Elsevier
  • Release Date : 2004-07-02
  • Total pages : 1396
  • ISBN : 9780080492148
  • File Size : 30,9 Mb
  • Total Download : 174
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Principles of Gender-Specific Medicine examines how normal human biology differs between men and women and how the diagnosis and treatment of disease differs as a function of gender. This revealing research covers various conditions that predominantly occur in men, and as well conditions that predominantly occur in women. Among the subjects covered are cardiovascular disease, mood disorders, the immune system, lung cancer as a consequence of smoking, osteoporosis, diabetes, obesity, and infectious diseases. * Gathers important information in the field of gender-based biology and clinical medicine, proving that a patient's sex is increasingly important in preventing illness, making an accurate diagnosis, and choosing safe and effective treatment of disease * Addresses gender-specific areas ranging from organ transplantation, gall bladder and biliary diseases, to the epidemiology of osteoporosis and fractures in men and women * Many chapters present questions about future directions of investigations

Exploring the Biological Contributions to Human Health

Exploring the Biological Contributions to Human Health
  • Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Understanding the Biology of Sex and Gender Differences
  • Publisher : National Academies Press
  • Release Date : 2001-07-02
  • Total pages : 288
  • ISBN : 0309132975
  • File Size : 27,7 Mb
  • Total Download : 417
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It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.

Principles of Gender-Specific Medicine

Principles of Gender-Specific Medicine
  • Author : Marianne J. Legato
  • Publisher : Academic Press
  • Release Date : 2017-05-15
  • Total pages : 792
  • ISBN : 9780128035429
  • File Size : 47,5 Mb
  • Total Download : 264
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The announcement that we had decoded the human genome in 2000 ushered in a new and unique era in biomedical research and clinical medicine. This Third Edition of Principles of Gender-Specific Medicine focuses, as in the past two editions, on the essentials of sexual dimorphism in human physiology and pathophysiology, but emphasizes the latest information about molecular biology and genomic science in a variety of disciplines. Thus, this edition is a departure from the previous two; the editor solicited individual manuscripts from innovative scientists in a variety of fields rather than the traditional arrangement of sections devoted to the various subspecialties of medicine edited by section chiefs. Wherever it was available, these authors incorporated the latest information about the impact of the genome and the elements that modify its expression on human physiology and illness. All chapters progress translationally from basic science to the clinical applications of gender-specific therapy and suggest the most important topics for future investigation. This book is essential reading for all biomedical investigators and medical educators involved in gender-specific medicine. It will also be useful for primary care practitioners who need information about the importance of sex and gender in the prevention, diagnosis and treatment of illness. Outlines sex-specific differences in normal human function and explains the impact of age, hormones, and environment on the incidence and outcome of illness Reflects the latest information about the molecular basis of the sexual dimorphism in human physiology and the experience of disease Reviews the implications of our ever-improving ability to describe the genetic basis of vulnerability to disease and our capacity to alter the genome itself Illustrates the importance of new NIH guidelines that urge the inclusion of sex as a variable in research protocols

Sex Differences in Sports Medicine

Sex Differences in Sports Medicine
  • Author : Ellen Casey, MD,Monica Rho, MD,Joel Press, MD
  • Publisher : Springer Publishing Company
  • Release Date : 2016-05-28
  • Total pages : 320
  • ISBN : 9781617052491
  • File Size : 28,8 Mb
  • Total Download : 279
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This is the first book dedicated to the musculoskeletal, physiological, hormonal, and other differences between the sexes as they manifest in sports medicine. Organized anatomically from head to toe, this unique reference focuses on the sex-specific differences of men and women to inform clinical care and the management of common sports injuries. Other chapters cover nutrition, hormones, concussion, pain, sports cardiology and pulmonology, and the particular care of adolescent and geriatric patients. The editors have assembled a world-class team of specialists to collaborate on each chapter, and specially commissioned illustrations and tables help visualize the data and findings. While some books focus on “the female athlete” as a discrete category, this book discusses how the many physical stresses of athletics affect both sexes based on the inherent biological differences. The goal is to foster a more comprehensive understanding of the latest research and practice in sports medicine as it applies to all patients. As the field of sports medicine has grown exponentially over the last few decades, this book will serve as an essential resource for physicians, trainers, coaches, and anyone involved in athletics and medicine. Key Features: Provides an evidence-based review of how sex differences affect the risk of injury, presentation, and clinical course of sports-related injuries Anatomically based chapters highlight differences in static structures, dynamic movement, and pathology between the sexes Authors summarize key differences at the end of each chapter Includes special chapters on running and throwing, sports cardiology, sports pulmonology, nutrition, and unique athlete populations

Sex Differences in Depression

Sex Differences in Depression
  • Author : Susan Nolen-Hoeksema
  • Publisher : Stanford University Press
  • Release Date : 1990
  • Total pages : 280
  • ISBN : 0804716404
  • File Size : 13,6 Mb
  • Total Download : 519
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Women are twice as likely as men to experience protracted sadness, apathy, low self-esteem, and other symptoms of depression. How can we account for this sex difference? Several explanations have been proposed, some dating back many years. This book critically examines the evidence for each explanation in an attempt to discover what we do and do not know about sex differences in depression. It is a landmark review of the historical, theoretical and empirical approaches to sex differences in depression. Nolen-Hoeksema presents a fresh historical review, makes theoretical criticisms and offers clear and challenging avenues for future research and practical applications.

Sex and Gender Aspects in Clinical Medicine

Sex and Gender Aspects in Clinical Medicine
  • Author : Sabine Oertelt-Prigione,Vera Regitz-Zagrosek
  • Publisher : Springer Science & Business Media
  • Release Date : 2011-11-15
  • Total pages : 204
  • ISBN : 0857298321
  • File Size : 48,8 Mb
  • Total Download : 442
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This book is a concise, easy to read professional text with a focus on practical aspects. All chapters include tables on sex/gender differences in symptoms and management and a series of suggestions to the novice in the field. Chapters are specialty-specific. The focus is not on women’s health, but the presentation of differences in clinical symptoms, management and outcomes in women and men. Gender Medicine strives to employ the knowledge about these differences to improve diagnosis, better understand pathogenesis and advance patient-oriented therapy.

Sex Differences

Sex Differences
  • Author : Linda Mealey
  • Publisher : Unknown
  • Release Date : 2000
  • Total pages : 480
  • ISBN : 0124874606
  • File Size : 11,5 Mb
  • Total Download : 701
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Sex Differences serves as an advanced text for courses in evolutionary and human biology, psychology, and sexuality and gender studies. It also serves as a reference source for academic professionals in these disciplines. The book covers the evolution of sex and sex differences, and sex differences and sexual strategies in non-human and human animals. The final chapter addresses issues of sex and gender in interpersonal relationships, organizations and politics. Diagrams, graphs, charts, and tables illustrate key concepts; cartoons and photos provide visual breaks and an element of humor. Key Features * Examines sexual differences from a multi-level comparative approach * Contains a thorough coverage of literature through 1998 and into 1999 * Illustrates pages with a generous use of cartoons, photos, figures, and diagrams * Invites bonus learning with special interest boxes interspersed throughout text * Presents a critical analysis * Includes a combination of feminist and evolutionary thinking

Management of Cardiovascular Disease in Women

Management of Cardiovascular Disease in Women
  • Author : Hanna Z. Mieszczanska,Gladys P. Velarde
  • Publisher : Springer Science & Business Media
  • Release Date : 2014-03-24
  • Total pages : 462
  • ISBN : 9781447155171
  • File Size : 50,8 Mb
  • Total Download : 936
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Cardiovascular disease is the leading cause of death in women in the US, with more women dying from heart disease than men. Women may have different presentation from men and often need a different approach to diagnosis and treatment. There are also unique topics of management of heart disease in women, including issues during pregnancy, lactation, and menopause. Many different health care providers, as well as cardiologists are involved in treating these patients. A manual reviewing diagnosis and treatment of cardiac disease in women would help providers without specific cardiology training to deliver care with greater efficiency. A practical and comprehensive guide geared towards these providers would be a highly practical and valuable resource that would be utilized in everyday practice in offices that include urban clinics, general medicine offices, obstetrics and gynecology offices, as well as in the surgical subspecialties. This book will be a highly practical resource that can be directly applied to the issues that arise in everyday practice. There is no available book on the market that focuses on a broader approach to cardiac disease in women or focuses on non-cardiology providers (and their trainees) who have the need to know more about treatment of cardiovascular disease in women.​

Invisible Women

Invisible Women
  • Author : Caroline Criado Perez
  • Publisher : Abrams
  • Release Date : 2019-03-12
  • Total pages : 422
  • ISBN : 9781683353140
  • File Size : 43,5 Mb
  • Total Download : 944
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#1 International Bestseller Winner of the 2019 Financial Times and McKinsey Business Book of the Year Award Winner of the 2019 Royal Society Science Book Prize A landmark, prize-winning, international bestselling examination of how a gender gap in data perpetuates bias and disadvantages women, now in paperback Data is fundamental to the modern world. From economic development to health care to education and public policy, we rely on numbers to allocate resources and make crucial decisions. But because so much data fails to take into account gender, because it treats men as the default and women as atypical, bias and discrimination are baked into our systems. And women pay tremendous costs for this insidious bias, in time, in money, and often with their lives. Celebrated feminist advocate Caroline Criado Perez investigates this shocking root cause of gender inequality in the award-winning, #1 international bestseller Invisible Women. Examining the home, the workplace, the public square, the doctor’s office, and more, Criado Perez unearths a dangerous pattern in data and its consequences on women’s lives. Product designers use a “one-size-fits-all” approach to everything from pianos to cell phones to voice recognition software, when in fact this approach is designed to fit men. Cities prioritize men’s needs when designing public transportation, roads, and even snow removal, neglecting to consider women’s safety or unique responsibilities and travel patterns. And in medical research, women have largely been excluded from studies and textbooks, leaving them chronically misunderstood, mistreated, and misdiagnosed. Built on hundreds of studies in the United States, in the United Kingdom, and around the world, and written with energy, wit, and sparkling intelligence, this is a groundbreaking, highly readable exposé that will change the way you look at the world.

Geigy Scientific Tables

Geigy Scientific Tables
  • Author : Cornelius Lentner
  • Publisher : Unknown
  • Release Date : 1981
  • Total pages : 288
  • ISBN : MINN:31951D00430287Z
  • File Size : 36,7 Mb
  • Total Download : 725
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PDF book entitled Geigy Scientific Tables written by Cornelius Lentner and published by Unknown which was released on 1981 with total hardcover pages 288, the book become popular and critical acclaim.

Biological Variation in Health and Illness

Biological Variation in Health and Illness
  • Author : Theresa Overfield
  • Publisher : CRC Press
  • Release Date : 1995-04-28
  • Total pages : 224
  • ISBN : 0849345774
  • File Size : 18,7 Mb
  • Total Download : 982
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Specifically for the health professional, this book contains an extensive compilation of research findings on biologic variation by race, age, and gender relating to health and illness. Completely rewritten, revised, and updated, the Second Edition includes an increased discussion of biologic variation and expanded coverage of each chapter topic. This book provides a theoretical framework for understanding the mechanisms that influence biologic variation. It presents a well-documented discussion of research data and indicates areas where knowledge is lacking. A theoretical explanation is followed by examination of surface and anatomical variations, developmental variation, biochemical and enzymatic variations, disease susceptibility differences, and influence of the external variation. Consideration of sexual variation reveals more differences between the sexes than among races. Misconceptions about racial uniformity and diversity are exposed throughout the book. Tables of specific biologic variations allow easy reference and access to the literature.

Women, Work, and Health

Women, Work, and Health
  • Author : Marianne Frankenhaeuser,Ulf Lundberg,Margaret Chesney
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Total pages : 271
  • ISBN : 9781461537120
  • File Size : 27,7 Mb
  • Total Download : 991
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Until recently, studies of women's health received scant research attention in the context of the overall magnitude of research conducted on health. Even for health issues that affect both men and women, most research has been limited to male subjects, leaving a large gap in our knowledge base concerning women's health. Finally, the decade of the 1990s is ushering in a shift in this inequity. In 1990 the U.S. National Institutes of Health issued a compelling report citing the lack of sufficient research on women's health as a major gap in our knowledge, and a mandate has been issued to add women as study subjects in research or to document why they have not been included. Such directives will undoubtedly lead to a much-needed burgeoning of research activities in the area of women's health as we approach the twenty-first century. Despite limited research resources, however, there have been steady, scientifically rigorous voices in the wilderness for the last several years, and many of the best investigators are represented in this volume. These workers have led the vanguard in exploring psychosocial factors that are likely to differentially affect women's and men's health. For example, women and men engage in social roles that often differ, if not in quantity, then certainly in quality. Sex differences in role expectations, environmen tal qualities, role burdens related to the domains of work and family, and abilities to adapt to and cope with stressful situations may have a distinctive impact on health.

Promoting Cardiovascular Health in the Developing World

Promoting Cardiovascular Health in the Developing World
  • Author : Institute of Medicine,Board on Global Health,Committee on Preventing the Global Epidemic of Cardiovascular Disease: Meeting the Challenges in Developing Countries
  • Publisher : National Academies Press
  • Release Date : 2010-06-29
  • Total pages : 482
  • ISBN : 0309157617
  • File Size : 9,5 Mb
  • Total Download : 526
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Cardiovascular disease (CVD), once thought to be confined primarily to industrialized nations, has emerged as a major health threat in developing countries. Cardiovascular disease now accounts for nearly 30 percent of deaths in low and middle income countries each year, and is accompanied by significant economic repercussions. Yet most governments, global health institutions, and development agencies have largely overlooked CVD as they have invested in health in developing countries. Recognizing the gap between the compelling evidence of the global CVD burden and the investment needed to prevent and control CVD, the National Heart, Lung, and Blood Institute (NHLBI) turned to the IOM for advice on how to catalyze change. In this report, the IOM recommends that the NHLBI, development agencies, nongovernmental organizations, and governments work toward two essential goals: creating environments that promote heart healthy lifestyle choices and help reduce the risk of chronic diseases, and building public health infrastructure and health systems with the capacity to implement programs that will effectively detect and reduce risk and manage CVD. To meet these goals, the IOM recommends several steps, including improving cooperation and collaboration; implementing effective and feasible strategies; and informing efforts through research and health surveillance. Without better efforts to promote cardiovascular health, global health as a whole will be undermined.