Receptors In The Evolution And Development Of The Brain

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Receptors in the Evolution and Development of the Brain

Receptors in the Evolution and Development of the Brain
  • Author : Richard E. Fine
  • Publisher : Academic Press
  • Release Date : 2019-06-15
  • Total pages : 282
  • ISBN : 9780128110133
  • File Size : 9,9 Mb
  • Total Download : 109
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Receptors in the Evolution and Development of the Brain: Matter into Mind presents the key role of receptors and their cognate ligands in wiring the mammalian brain from an evolutionary developmental biology perspective. It examines receptor function in the evolution and development of the nervous system in the large vertebrate brain, and discusses rapid eye movement sleep and apoptosis as mechanisms to destroy miswired neurons. Possible links between trophic deficits and connectional diseases including Alzheimer’s, Parkinson’s, and ALS are also discussed. This book is extremely useful to those with an interest in the molecular and cellular neurosciences, including those in cognitive and clinical branches of this subject, and anyone interested in how the incredibly complex human brain can build itself. Provides an understanding of the key role receptors play in brain development and the selection process necessary to construct a large brain Traces the evolution of receptors from the most primitive organisms to humans Emphasizes the roles that REM sleep and apoptosis play in this selection via trophic factors and receptors Describes the role that trophic factor-receptor interactions play throughout life and how trophic deficits can lead to connectional diseases, including Alzheimer's, Parkinson's and ALS Provides a potential mechanism whereby neuronal stem cells can cure these diseases

Human Brain Evolution

Human Brain Evolution
  • Author : Stephen Cunnane,Kathlyn Stewart
  • Publisher : John Wiley & Sons
  • Release Date : 2010-07-30
  • Total pages : 232
  • ISBN : 0470609877
  • File Size : 26,6 Mb
  • Total Download : 635
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The evolution of the human brain and cognitive ability is one of the central themes of physical/biological anthropology. This book discusses the emergence of human cognition at a conceptual level, describing it as a process of long adaptive stasis interrupted by short periods of cognitive advance. These advances were not linear and directed, but were acquired indirectly as part of changing human behaviors, in other words through the process of exaptation (acquisition of a function for which it was not originally selected). Based on studies of the modem human brain, certain prerequisites were needed for the development of the early brain and associated cognitive advances. This book documents the energy and nutrient constraints of the modern brain, highlighting the significant role of long-chain polyunsaturated fatty acids (LC-PUFA) in brain development and maintenance. Crawford provides further emphasis for the role of essential fatty acids, in particular DHA, in brain development, by discussing the evolution of the eye and neural systems. This is an ideal book for Graduate students, post docs, research scientists in Physical/Biological Anthropology, Human Biology, Archaeology, Nutrition, Cognitive Science, Neurosciences. It is also an excellent selection for a grad student discussion seminar.

Discovering the Brain

Discovering the Brain
  • Author : National Academy of Sciences,Institute of Medicine,Sandra Ackerman
  • Publisher : National Academies Press
  • Release Date : 1992-01-01
  • Total pages : 195
  • ISBN : 9780309045292
  • File Size : 47,6 Mb
  • Total Download : 652
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The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."

Evolution of Nervous Systems

Evolution of Nervous Systems
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2016-11-23
  • Total pages : 2007
  • ISBN : 9780128040966
  • File Size : 49,5 Mb
  • Total Download : 696
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Evolution of Nervous Systems, Second Edition is a unique, major reference which offers the gold standard for those interested both in evolution and nervous systems. All biology only makes sense when seen in the light of evolution, and this is especially true for the nervous system. All animals have nervous systems that mediate their behaviors, many of them species specific, yet these nervous systems all evolved from the simple nervous system of a common ancestor. To understand these nervous systems, we need to know how they vary and how this variation emerged in evolution. In the first edition of this important reference work, over 100 distinguished neuroscientists assembled the current state-of-the-art knowledge on how nervous systems have evolved throughout the animal kingdom. This second edition remains rich in detail and broad in scope, outlining the changes in brain and nervous system organization that occurred from the first invertebrates and vertebrates, to present day fishes, reptiles, birds, mammals, and especially primates, including humans. The book also includes wholly new content, fully updating the chapters in the previous edition and offering brand new content on current developments in the field. Each of the volumes has been carefully restructured to offer expanded coverage of non-mammalian taxa, mammals, primates, and the human nervous system. The basic principles of brain evolution are discussed, as are mechanisms of change. The reader can select from chapters on highly specific topics or those that provide an overview of current thinking and approaches, making this an indispensable work for students and researchers alike. Presents a broad range of topics, ranging from genetic control of development in invertebrates, to human cognition, offering a one-stop resource for the evolution of nervous systems throughout the animal kingdom Incorporates the expertise of over 100 outstanding investigators who provide their conclusions in the context of the latest experimental results Presents areas of disagreement and consensus views that provide a holistic view of the subjects under discussion

The Accidental Mind

The Accidental Mind
  • Author : David J. Linden
  • Publisher : Harvard University Press
  • Release Date : 2012-11-01
  • Total pages : 286
  • ISBN : 9780674076617
  • File Size : 22,7 Mb
  • Total Download : 655
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Linden sets the record straight about the construction of the human brain; rather than the “beautifully-engineered optimized device, the absolute pinnacle of design” portrayed in many dumbed-down text books, pop-science tomes, and education televisions programs, Linden’s organ is a complicated assembly of cobbled-together functionality that created the mind as a by-product of ad-hoc solutions to questions of survival. His guided tour of the glorious amalgam of “crummy parts” includes pit-stops in the histories and fundamentals of neurology, neural-psychology, physiology, molecular and cellular biology, and genetics.

Comparative Vertebrate Neuroanatomy

Comparative Vertebrate Neuroanatomy
  • Author : Ann B. Butler,William Hodos
  • Publisher : John Wiley & Sons
  • Release Date : 2005-09-02
  • Total pages : 600
  • ISBN : 9780471733836
  • File Size : 49,5 Mb
  • Total Download : 841
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Comparative Vertebrate Neuroanatomy Evolution and Adaptation Second Edition Ann B. Butler and William Hodos The Second Edition of this landmark text presents a broad survey ofcomparative vertebrate neuroanatomy at the introductory level,representing a unique contribution to the field of evolutionaryneurobiology. It has been extensively revised and updated, withsubstantially improved figures and diagrams that are usedgenerously throughout the text. Through analysis of the variationin brain structure and function between major groups ofvertebrates, readers can gain insight into the evolutionary historyof the nervous system. The text is divided into threesections: * Introduction to evolution and variation, including a survey ofcell structure, embryological development, and anatomicalorganization of the central nervous system; phylogeny and diversityof brain structures; and an overview of various theories of brainevolution * Systematic, comprehensive survey of comparative neuroanatomyacross all major groups of vertebrates * Overview of vertebrate brain evolution, which integrates thecomplete text, highlights diversity and common themes, broadensperspective by a comparison with brain structure and evolution ofinvertebrate brains, and considers recent data and theories of theevolutionary origin of the brain in the earliest vertebrates,including a recently proposed model of the origin of the brain inthe earliest vertebrates that has received strong support fromnewly discovered fossil evidence Ample material drawn from the latest research has been integratedinto the text and highlighted in special feature boxes, includingrecent views on homology, cranial nerve organization and evolution,the relatively large and elaborate brains of birds in correlationwith their complex cognitive abilities, and the current debate onforebrain evolution across reptiles, birds, and mammals. Comparative Vertebrate Neuroanatomy is geared to upper-levelundergraduate and graduate students in neuroanatomy, but anyoneinterested in the anatomy of the nervous system and how itcorresponds to the way that animals function in the world will findthis text fascinating.

The Brain

The Brain
  • Author : Rob DeSalle,Ian Tattersall
  • Publisher : Yale University Press
  • Release Date : 2012-04-30
  • Total pages : 369
  • ISBN : 9780300183566
  • File Size : 54,7 Mb
  • Total Download : 105
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“An engaging and complex examination of the development of the human brain throughout its evolutionary history” (Publishers Weekly). After several million years of jostling for ecological space, only one survivor from a host of hominid species remains standing: us. Human beings are extraordinary creatures, and it is the unprecedented human brain that makes them so. In this delightfully accessible book, the authors present the first full, step-by-step account of the evolution of the brain and nervous system. Tapping the very latest findings in evolutionary biology, neuroscience, and molecular biology, Rob DeSalle and Ian Tattersall explain how the cognitive gulf that separates us from all other living creatures could have occurred. They discuss • The development and uniqueness of human consciousness • How human and nonhuman brains work • The roles of different nerve cells • The importance of memory and language in brain functions, and much more Our brains, they conclude, are the product of a lengthy and supremely untidy history—an evolutionary process of many zigs and zags—that has accidentally resulted in a splendidly eccentric and creative product.

Evolution of the Brain: Creation of the Self

Evolution of the Brain: Creation of the Self
  • Author : John C. Eccles
  • Publisher : Routledge
  • Release Date : 2005-07-05
  • Total pages : 310
  • ISBN : 9781134968350
  • File Size : 29,8 Mb
  • Total Download : 892
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In this book, Nobel Prize-winner, Sir John Eccles, tells the story of how man came to be as he is, not only as an animal at the end of the hominid evolutionary line, but also as a human being possessed of reflective consciousness.

From Neurons to Neighborhoods

From Neurons to Neighborhoods
  • Author : National Research Council,Institute of Medicine,Board on Children, Youth, and Families,Committee on Integrating the Science of Early Childhood Development
  • Publisher : National Academies Press
  • Release Date : 2000-11-13
  • Total pages : 610
  • ISBN : 9780309069885
  • File Size : 29,8 Mb
  • Total Download : 204
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How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.

The Long Evolution of Brains and Minds

The Long Evolution of Brains and Minds
  • Author : Gerhard Roth
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-06-03
  • Total pages : 320
  • ISBN : 9789400762596
  • File Size : 28,8 Mb
  • Total Download : 325
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The main topic of the book is a reconstruction of the evolution of nervous systems and brains as well as of mental-cognitive abilities, in short “intelligence” from simplest organisms to humans. It investigates to which extent the two are correlated. One central topic is the alleged uniqueness of the human brain and human intelligence and mind. It is discussed which neural features make certain animals and humans intelligent and creative: Is it absolute or relative brain size or the size of “intelligence centers” inside the brains, the number of nerve cells inside the brain in total or in such “intelligence centers” decisive for the degree of intelligence, of mind and eventually consciousness? And which are the driving forces behind these processes? Finally, it is asked what all this means for the classical problem of mind-brain relationship and for a naturalistic theory of mind.

Survival of the Fattest

Survival of the Fattest
  • Author : Stephen C Cunnane
  • Publisher : World Scientific
  • Release Date : 2005-05-06
  • Total pages : 368
  • ISBN : 9789814480826
  • File Size : 13,6 Mb
  • Total Download : 184
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' How did humans evolve larger and more sophisticated brains? In general, evolution depends on a special combination of circumstances: part genetics, part time, and part environment. In the case of human brain evolution, the main environmental influence was adaptation to a 'shore-based' diet, which provided the world's richest source of nutrition, as well as a sedentary lifestyle that promoted fat deposition. Such a diet included shellfish, fish, marsh plants, frogs, bird's eggs, etc. Humans and, and more importantly, hominid babies started to get fat, a crucial distinction that led to the development of larger brains and to the evolution of modern humans. A larger brain is expensive to maintain and this increasing demand for energy results in, succinctly, survival of the fattest. Contents:The Human Brain: Unique Yet Vulnerable:Human Evolution: A Brief OverviewThe Human Brain: Evolution of Larger Size and PlasticityDefining Characteristics: Vulnerability and High Energy RequirementFatness in Human Babies: Insurance for the Developing BrainNutrition: The Key to Normal Human Brain DevelopmentIodine: The Primary Brain Selective NutrientIron, Copper, Zinc and Selenium: The Other Brain Selective MineralsDocosahexaenoic Acid: The Brain Selective Fatty AcidThe Shore-Based Scenario:Genes, Brain Function and Human Brain EvolutionBringing the Environment and Diet into PlayThe Shore-Based Scenario: Why Survival Misses the PointEarlier VersionsThe EvidenceHow Would It Work?Survival of the Fattest Readership: General, and those with an interest in origins of humans especially human intelligence (the big brain). Keywords:Human Brain;Brain Evolution;Dietary Fat;Body Fat;Human Infant;Fat Babies;HominidsKey Features:A new theory of human brain evolutionThe novel concept that shorelines provided a unique food resourceThe novel concept that fat babies were the key to human brain evolutionReviews:“The nutritionist's perspective that brings energy, fatty acid metabolism, and nutrition to the fore makes this account a provocative and fast-paced one. Readers will be challenged and intrigued by this well thought-out volume.”Joyce A Nettleton, DSc, RD ScienceVoice Consulting Denver, Colorado “Anyone interested in how humans evolved will find much of interest in this book … the main thread of the argument seems so plausible that many readers will want to delve further by way of a number of the items listed in the bibliography.”Henry H Bauer Professor Emeritus of Chemistry & Science Studies, Dean Emeritus of Arts & Sciences Virginia Polytechnic Institute & State University “This book is full of interesting facts about our brains and about nutrition and brain and body biochemistry. Cunnane weaves a very complex and multi-faceted hypothesis systematically and relatively clearly … I found the book thought-provoking. It shares data and ideas that are relatively novel and interesting …”European Neurology '

Neurobiology and the Development of Human Morality: Evolution, Culture, and Wisdom (Norton Series on Interpersonal Neurobiology)

Neurobiology and the Development of Human Morality: Evolution, Culture, and Wisdom (Norton Series on Interpersonal Neurobiology)
  • Author : Darcia Narvaez
  • Publisher : W. W. Norton & Company
  • Release Date : 2014-10-20
  • Total pages : 456
  • ISBN : 9780393709674
  • File Size : 15,7 Mb
  • Total Download : 237
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Winner of the Inaugural Expanded Reason Award: A wide-ranging exploration of the role of childhood experiences in adult morality. Moral development has traditionally been considered a matter of reasoning—of learning and acting in accordance with abstract rules. On this model, largely taken for granted in modern societies, acts of selfishness, aggression, and ecological mindlessness are failures of will, moral problems that can be solved by acting in accordance with a higher rationality. But both ancient philosophy and recent scientific scholarship emphasize implicit systems, such as action schemas and perceptual filters that guide behavior and shape human development. In this integrative book, Darcia Narvaez argues that morality goes “all the way down” into our neurobiological and emotional development, and that a person’s moral architecture is largely established early on in life. Moral rationality and virtue emerge “bottom up” from lived experience, so it matters what that experience is. Bringing together deep anthropological history, ethical philosophy, and contemporary neurobiological science, she demonstrates where modern industrialized societies have fallen away from the cultural practices that made us human in the first place. Neurobiology and the Development of Human Morality advances the field of developmental moral psychology in three key ways. First, it provides an evolutionary framework for early childhood experience grounded in developmental systems theory, encompassing not only genes but a wide array of environmental and epigenetic factors. Second, it proposes a neurobiological basis for the development of moral sensibilities and cognition, describing ethical functioning at multiple levels of complexity and context before turning to a theory of the emergence of wisdom. Finally, it embraces the sociocultural orientations of our ancestors and cousins in small-band hunter-gatherer societies—the norm for 99% of human history—for a re-envisioning of moral life, from the way we value and organize child raising to how we might frame a response to human-made global ecological collapse. Integrating the latest scholarship in clinical sciences and positive psychology, Narvaez proposes a developmentally informed ecological and ethical sensibility as a way to self-author and revise the ways we think about parenting and sociality. The techniques she describes point towards an alternative vision of moral development and flourishing, one that synthesizes traditional models of executive, top-down wisdom with “primal” wisdom built by multiple systems of biological and cultural influence from the ground up.

Neurobiology of Monotremes

Neurobiology of Monotremes
  • Author : Ken Ashwell
  • Publisher : CSIRO PUBLISHING
  • Release Date : 2013-12
  • Total pages : 536
  • ISBN : 9780643103153
  • File Size : 50,9 Mb
  • Total Download : 187
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Details the development, structure, function and behavioural ecology of the monotremes.

Adaptive Function and Brain Evolution

Adaptive Function and Brain Evolution
  • Author : Agustín González,Fernando Martinez-Garcia,Luis Puelles,Hans J Ten Donkelaar
  • Publisher : Frontiers E-books
  • Release Date : 2014-10-27
  • Total pages : 267
  • ISBN : 9782889193066
  • File Size : 29,5 Mb
  • Total Download : 649
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The brain of each animal shows specific traits that reflect its phylogenetic history and its particular lifestyle. Therefore, comparing brains is not just a mere intellectual exercise, but it helps understanding how the brain allows adaptive behavioural strategies to face an ever-changing world and how this complex organ has evolved during phylogeny, giving rise to complex mental processes in humans and other animals. These questions attracted scientists since the times of Santiago Ramon y Cajal one of the founders of comparative neurobiology. In the last decade, this discipline has undergone a true revolution due to the analysis of expression patterns of morphogenetic genes in embryos of different animals. The papers of this e-book are good examples of modern comparative neurobiology, which mainly focuses on the following four Grand Questions: a) How are different brains built during ontogeny? b) What is the anatomical organization of mature brains and how can they be compared? c) How do brains work to accomplish their function of ensuring survival and, ultimately, reproductive success? d) How have brains evolved during phylogeny? The title of this e-book, Adaptive Function and Brain Evolution, stresses the importance of comparative studies to understand brain function and, the reverse, of considering brain function to properly understand brain evolution. These issues should be taken into account when using animals in the research of mental function and dysfunction, and are fundamental to understand the origins of the human mind.

Micro-, Meso- and Macro-Dynamics of the Brain

Micro-, Meso- and Macro-Dynamics of the Brain
  • Author : György Buzsáki,Yves Christen
  • Publisher : Springer
  • Release Date : 2016-05-02
  • Total pages : 172
  • ISBN : 9783319288024
  • File Size : 45,6 Mb
  • Total Download : 914
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This book brings together leading investigators who represent various aspects of brain dynamics with the goal of presenting state-of-the-art current progress and address future developments. The individual chapters cover several fascinating facets of contemporary neuroscience from elementary computation of neurons, mesoscopic network oscillations, internally generated assembly sequences in the service of cognition, large-scale neuronal interactions within and across systems, the impact of sleep on cognition, memory, motor-sensory integration, spatial navigation, large-scale computation and consciousness. Each of these topics require appropriate levels of analyses with sufficiently high temporal and spatial resolution of neuronal activity in both local and global networks, supplemented by models and theories to explain how different levels of brain dynamics interact with each other and how the failure of such interactions results in neurologic and mental disease. While such complex questions cannot be answered exhaustively by a dozen or so chapters, this volume offers a nice synthesis of current thinking and work-in-progress on micro-, meso- and macro- dynamics of the brain.

Arthropod Brain

Arthropod Brain
  • Author : A. P. Gupta
  • Publisher : Wiley-Interscience
  • Release Date : 1987-09-29
  • Total pages : 616
  • ISBN : UCAL:B4457131
  • File Size : 40,8 Mb
  • Total Download : 730
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The definitive textbook and reference guide to the arthropod brain. The material is arranged logically in three sections. Section I, on evolution, includes a discussion on the presence of a fourth component, tetrocerebrum in the insect brain in addition to the three commonly recognized parts, and the evolutionary trends in the central and mushroom bodies in major arthropod groups. A section on structure and function includes detailed ultrastructural studies of the brain as well as studies of the mechanoreceptory centers, peripheral sensory coding and sensilla function, and antennal information processing. Also examines biochemical topics such as bioamines and mucosubstances, their respective roles in brain function, and various techniques of brain research.

Phylogeny and Development of Catecholamine Systems in the CNS of Vertebrates

Phylogeny and Development of Catecholamine Systems in the CNS of Vertebrates
  • Author : Wilhelmus J. A. Smeets,Anton Reiner
  • Publisher : Cambridge University Press
  • Release Date : 1994-10-13
  • Total pages : 510
  • ISBN : 0521442516
  • File Size : 26,5 Mb
  • Total Download : 402
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A thorough analysis of catecholamine systems in a wide range of vertebrates by experts. The book will be of interest to researchers and postgraduates of neuroscience, neurobiology, zoology, medicine and physiology.

The Wiley Handbook of Evolutionary Neuroscience

The Wiley Handbook of Evolutionary Neuroscience
  • Author : Stephen V. Shepherd
  • Publisher : John Wiley & Sons
  • Release Date : 2017-01-30
  • Total pages : 602
  • ISBN : 9781119994695
  • File Size : 51,9 Mb
  • Total Download : 217
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Comprehensive and authoritative, The Wiley Handbook of Evolutionary Neuroscience unifies the diverse strands of an interdisciplinary field exploring the evolution of brains and cognition. A comprehensive reference that unifies the diverse interests and approaches associated with the neuroscientific study of brain evolution and the emergence of cognition Tackles some of the biggest questions in neuroscience including what brains are for, what factors constrain their biological development, and how they evolve and interact Provides a broad and balanced view of the subject, reviewing both vertebrate and invertebrate anatomy and emphasizing their shared origins and mechanisms Features contributions from highly respected scholars in their fields

The Evolution of Intelligent Systems

The Evolution of Intelligent Systems
  • Author : K. Richardson
  • Publisher : Springer
  • Release Date : 2010-10-20
  • Total pages : 234
  • ISBN : 9780230299245
  • File Size : 30,5 Mb
  • Total Download : 454
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How could something as seemingly transcendental as the human mind have arisen from far simpler material beginnings? This book provides a comprehensive overview of evolution from pre-life and early life forms through increasing complexity to advanced cognitive systems using a new framework based on dynamic systems theory.

Serotonin

Serotonin
  • Author : Paul M. Pilowsky
  • Publisher : Academic Press
  • Release Date : 2018-09-21
  • Total pages : 420
  • ISBN : 9780128005842
  • File Size : 17,8 Mb
  • Total Download : 953
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Serotonin: The Mediator That Spans Evolution provides a comprehensive review of the widespread roles for serotonin in respiratory, cardiovascular and thermoregulatory control, and for growth and development in early life. This important resource highlights serotonin’s role in normal (unstressed) conditions, and in response to a variety of physiological stressors. It focuses on new animal models, comparing and contrasting data from mice and rats. In addition, the book compares and contrasts the physiological effects of brain and blood serotonin systems and includes new data suggesting that the influence of serotonin is in part through the regulation of gene expression. Finally, it discusses the role of serotonin system dysfunction in a variety of pathophysiological conditions, including sleep apnea, obesity and hypertension, and presents compelling evidence that this dysfunction is involved in Sudden Infant Death Syndrome (SIDS). Includes the latest information on new animal models of serotonin system dysfunction Explores the wide scope of serotonin’s influence on multiple organ and physiological systems Highlights the autonomous functioning of the brain and body serotonin systems Provides compelling evidence of serotonin dysfunction in SIDS, a leading cause of death in infancy

Zero to Birth

Zero to Birth
  • Author : William A. Harris
  • Publisher : Princeton University Press
  • Release Date : 2022-05-03
  • Total pages : 272
  • ISBN : 9780691237077
  • File Size : 16,8 Mb
  • Total Download : 227
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A revelatory tale of how the human brain develops, from conception to birth and beyond By the time a baby is born, its brain is equipped with billions of intricately crafted neurons wired together through trillions of interconnections to form a compact and breathtakingly efficient supercomputer. Zero to Birth takes you on an extraordinary journey to the very edge of creation, from the moment of an egg’s fertilization through each step of a human brain’s development in the womb—and even a little beyond. As pioneering experimental neurobiologist W. A. Harris guides you through the process of how the brain is built, he takes up the biggest questions that scientists have asked about the developing brain, describing many of the thrilling discoveries that were foundational to our current understanding. He weaves in a remarkable evolutionary story that begins billions of years ago in the Proterozoic eon, when multicellular animals first emerged from single-cell organisms, and reveals how the growth of a fetal brain over nine months reflects the brain’s evolution through the ages. Our brains have much in common with those of other animals, and Harris offers an illuminating look at how comparative animal studies have been crucial to understanding what makes a human brain human. An unforgettable chronicle of one of nature’s greatest achievements, Zero to Birth describes how the brain’s incredible feat of orchestrated growth ensures that every brain is unique, and how breakthroughs at the frontiers of science are helping us to decode many traits that only reveal themselves later in life.