Principles Of Gliopathology

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• Author : Alexei Verkhratsky,Arthur Butt
• Publisher : Elsevier
• Release Date : 2023-05-12
• Total pages : 732
• ISBN : 9780128215661
• File Size : 20,9 Mb
• Total Download : 367
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Download Neuroglia: Function and Pathology in PDF, Epub, and Kindle

Diverse specialised neuroglial cells guarantee the development, preservation, and health of the central nervous system, the peripheral nervous system, the enteric nervous system, and the special senses. In the central nervous system, it is the astrocytes, oligodendrocytes, and microglia that safeguard nerve cell function and integrity that controls all behaviours and encompasses the cerebral cortex of the brain which is the root of humanity. In the peripheral nervous system, Schwann cells play the leading role, together with satellite glial cells of the sensory and autonomic ganglia, ensuring correct communication between the organs and tissues with the brain and the spinal cord. In the enteric nervous system, specialised enteric glial cells maintain all aspects of gastrointestinal function. Then there are distinctive glial cells of the special senses that ensure how the body perceives and reacts to its environment. In pathology, neuroglia strive to protect the diverse cellular components of the nervous system and are responsible for a proactive programme of posttraumatic restructuring that is aimed at recovery of life-sustaining function. Neuroglia: Function and Pathology provides a highly original and comprehensive account of the physiology and pathophysiology of glial cells in the central and peripheral nervous systems. The first part of the book provides a far-reaching description of glial cell form and function, from their evolution in invertebrates to their complexity in humans, encompassing the developmental origin of the varied glial cell types and their diversity of morphology, molecular biology and cellular physiology. The second part of the book is devoted to an all-embracing evaluation of glial cell pathophysiology, commencing with definitive explanations of the fundamental pathologies of the main glial cell types, and ending in a systematic examination of glial contributions to specific neurological diseases. This book emphasises the central roles played by the different classes of neuroglial cells in the progression and outcome of neurological disorders of the central and peripheral nervous systems and highlights potential of glial cells as therapeutic targets. The book contains more than 2500 key references from over 150 years of glial research and is superbly illustrated with over 350 original and explanatory full colour figures that describe the diverse characteristics and properties of glial cells in health and disease. Under the same cover, this book combines an authoritative reference book for research and clinical neuroscientists and at the same time serves as an instructive textbook for students of neuroscience, from undergraduates to postgraduates. Single volume covering key aspects of glial cell physiology and pathology In depth overview of the history of glial cell research Comprehensive review of glial cell physiology and pathology Authoritative special chapters on the major neurological diseases Full colour throughout, with 360 illustrations

• Author : Marc Lewis
• Publisher : Doubleday Canada
• Release Date : 2015-08-04
• Total pages : 320
• ISBN : 9780385682299
• File Size : 13,7 Mb
• Total Download : 642
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Download The Biology of Desire in PDF, Epub, and Kindle

Through the vivid, true stories of five people who journeyed into and out of addiction, a renowned neuroscientist explains why the “disease model” of addiction is wrong and illuminates the path to recovery. The psychiatric establishment and rehab industry in the Western world have branded addiction a brain disease, based on evidence that brains change with drug use. But in The Biology of Desire, cognitive neuroscientist and former addict Marc Lewis makes a convincing case that addiction is not a disease, and shows why the disease model has become an obstacle to healing. Lewis reveals addiction as an unintended consequence of the brain doing what it’s supposed to do—seek pleasure and relief—in a world that’s not cooperating. Brains are designed to restructure themselves with normal learning and development, but this process is accelerated in addiction when highly attractive rewards are pursued repeatedly. Lewis shows why treatment based on the disease model so often fails, and how treatment can be retooled to achieve lasting recovery, given the realities of brain plasticity. Combining intimate human stories with clearly rendered scientific explanation, The Biology of Desire is enlightening and optimistic reading for anyone who has wrestled with addiction either personally or professionally.

• Author : Adrian Winship
• Publisher : Unknown
• Release Date : 2019-06-14
• Total pages : 250
• ISBN : 1733092315
• File Size : 25,5 Mb
• Total Download : 727
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Download Neuroplasticity in PDF, Epub, and Kindle

If you've always wanted to learn about the amazing breakthroughs people are currently accomplishing after integrating neuroplasticity in their lives AND how you can apply this exciting phenomenon to your life, then keep reading... Are you sick and tired of bad habits dictating your life? Have you tried endless other solutions but NOTHING seems to work for more than a few weeks? Do you finally want to say goodbye to trauma/PTSD and discover something which works for you? If so, then you've come to the right place! You see, practical applications of neuroplasticity to your life doesn't have to be difficult! Even if you know absolutely nothing about neuroplasticity! In fact, it's easier than you think. Studies on neuroplasticity conducted by Dr. Merzenich at The University of California at San Francisco have collectively demonstrated that many aspects of your brain power, intelligence, or control can be improved by intense and appropriately targeted behavioral training. The Journal of Neuropsychiatry states, "The brain, once considered to be a fixed and stable organ, is now viewed as dynamic, flexible, and adaptive. Efforts are beginning to focus on ways to harness the plastic qualities of the brain for treatment and recovery." Which means you can utilize principles of neuroplasticity to improve cognitive flexibility, eliminate depression, and so much more without experiencing any negative side effects and without spending a lot of money! Here's just a tiny fraction of what you'll discover: A crash course on what exactly neuroplasticity is and why you need to be excited about this astounding discovery! Why the most popular brain games on the market are actually ineffective and what you should be playing instead 12 interpersonal exercises you can execute immediately in your daily life to improve your cognitive flexibility without taking up a lot of your time How to change bad habits using neuroplasticity with 5 easy steps How neuroplasticity can be used to defeat addictions, phobias, insomnia and so much more! The simple yet effective 6-step process used by Cognitive Behavioral Therapists to stimulate neuroplasticity in the brain Why positive thinking may actually be hindering your progress and what you should be doing instead A FREE gift that I have personally used for my own healing that you can now take advantage of too! ...and much, much more! Take a second now to imagine how you'll feel once you conquer whatever ails you using the principles in this book and how your family and friends will react when they see the new you! So even if you've tried every self help program on the market, you can improve your life and start living with neuroplasticity! So, if you have a burning desire to start living life to the max then claim your copy now and make the greatest investment in yourself!

• Author : Kate E. Reynolds
• Publisher : Jessica Kingsley Publishers
• Release Date : 2014-08-21
• Total pages : 36
• ISBN : 9780857009340
• File Size : 22,7 Mb
• Total Download : 989
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Download What's Happening to Tom? in PDF, Epub, and Kindle

Tom notices that his body is changing. Tom's voice is different and hair is growing in new places. There are other changes happening too. Tom learns that he has started growing into a man. Following Tom as he begins to notice changes to his body, this simple resource helps parents and carers teach boys with autism or other special needs about puberty. It covers all the changes that they will experience, both emotional such as new feelings and physical such as wet dreams. This fully illustrated positive and entertaining book provides the perfect opportunity to talk about puberty with boys and young men with autism or special needs.

• Author : Emma Young
• Publisher : John Murray
• Release Date : 2022-04-14
• Total pages : 384
• ISBN : 1473690757
• File Size : 34,8 Mb
• Total Download : 355
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Download Super Senses in PDF, Epub, and Kindle

From childhood we are told that humans have five senses: hearing, sight, smell, taste and touch. But your school teachers were wrong. All of us have at least thirty-two senses - and our survival depends on them. In Super Senses, award-winning science journalist Emma Young explores our surprisingly rich sensory lives. She discovers why the main function of our ears isn't for hearing; how we can find taste receptors in places other than our tongues; how improving your sense of smell might increase your enjoyment of sex; why the semi-nomadic Himba people can't distinguish between blue and green but Russians can see two shades of blue; and how touch can confuse the way your brain registers pain. She also delves into the 'new' senses - including balance and internal-sensing - without which you'd be dead within minutes. And by exploring the lives of people with sensory over-sensitivity to those who feel no emotion at all, Young shows that our senses don't simply inform us, they form us. Traversing cutting-edge research and drawing on the experiences at the extremes of the sensitivity spectrums, as well as stories from history and anthropology, Super Senses takes readers on a journey that will make them see themselves, and the world around them, through entirely fresh eyes.

• Author : Judy Craft,Christopher Gordon,Adriana P. Tiziani,Sue E. Huether,Kathryn L. McCance,Valentina L. Brashers
• Publisher : Elsevier Health Sciences
• Release Date : 2013-04-26
• Total pages : 1200
• ISBN : 9780729579513
• File Size : 27,7 Mb
• Total Download : 560
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Download Understanding Pathophysiology - ANZ adaptation in PDF, Epub, and Kindle

A new pathophysiology textbook specifically for Australian and New Zealand nursing studentsUnderstanding Pathophysiology provides nursing students with the optimal balance between science, clinical case material and pharmacology. With entrenched bio-medical terminology that can be difficult to relate to nursing practice, pathophysiology is a complex, though essential, component of all undergraduate nursing courses. Understanding Pathophysiology: ANZ Edition overcomes this difficulty by presenting the topic in an accessible manner appropriate to undergraduate nursing students in Australia and New Zealand. The book prioritises diseases relevant to nursing students and presents them according to prevalence and rate of incidence in Australia and New Zealand. This focused approach prepares students for the presentations they will experience in a clinical setting. Understanding Pathophysiology: ANZ Edition explores each body system first by structure and function, then by alteration. This establishes the physiology prior to addressing the diseases relative to the system and allows students to analyse and compare the normal versus altered state. This local edition of Understanding Pathophysiology incorporates a lifespan approach and explores contemporary health with specific chapters on stress, genes and the environment, obesity and diabetes, cancer, mental illness and Indigenous health issues. Clinical case studies are included in each chapter, with each patient case study highlighting the relevant medical symptoms of a given disease within a clinical setting. This is then analysed with respect to the relevancy of each symptom, their respective affect on body systems and the best course of pharmacological treatment. Elsevier’s Evolve website provides extensive support materials for students and lecturers. Also available for purchase with this textbook is an e-book, Pathophysiology Online – a set of online modules, and a mobile study guide application. • pathophysiology presented at an appropriate level for undergraduate nursing students in Australia and New Zealand • an adaptation of a US edition – Understanding Pathophysiology, 4th Edition • diseases are addressed according to prevalence, incidence and relevance • a ‘systems’ approach is incorporated with a ‘lifespan’ approach within the alterations chapters • a new section on contemporary health issues examines the effects of an aging population and lifestyle choices on a society’s overall health • new chapters on topics including homeostasis; genes and the environment; obesity and diabetes; mental health and Indigenous health issues • chapter outlines and key terms appear at the beginning of each chapter • concept maps provide visual representation of the key concepts addressed in each chapter • clinical case studies feature in each chapter to bring pathophysiology into practice • helpful ‘focus on learning’ boxes in each chapter • key terms are bolded in the text and listed in the glossary • summaries of main points feature in each chapter • review questions at chapter end are accompanied by answers provided online

• Author : Sue E. Huether,Kathryn L. McCance
• Publisher : Mosby Incorporated
• Release Date : 2007-11-01
• Total pages : 1194
• ISBN : 0323055591
• File Size : 33,5 Mb
• Total Download : 613
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Download Understanding Pathophysiology in PDF, Epub, and Kindle

This convenient, money saving package is a must have for students! It includes Understanding Pathophysiology, 4th edition and Study Guide and Workbook for Understanding Pathophysiology, 4th edition.

• Author : Marie-Francoise Chesselet
• Publisher : Springer Science & Business Media
• Release Date : 2000-10-19
• Total pages : 410
• ISBN : 9781592590063
• File Size : 50,8 Mb
• Total Download : 316
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Download Molecular Mechanisms of Neurodegenerative Diseases in PDF, Epub, and Kindle

With the unprecedented identification of new mutation mechanisms in neurodegenerative diseases and the emergence of common mechanisms among diseases that were once considered unrelated, neurobiologists are poised for the development of new therapies based on high throughput screenings and a better understanding of the molecular and cellular mechanisms leading to neurodegeneration. In Molecular Mechanisms of Neurodegenerative Diseases, Marie-Francoise Chesselet, MD, PhD, and a panel of leading researchers and neurologists from industry and academia critically review the most recent advances from different yet complementary points of view. Focusing on Alzheimer's, Parkinson's, and CAG triplet repeat diseases, the authors show how studies of cellular and genetically engineered animal models have enhanced our understanding of the molecular mechanisms of neurodegenerative diseases and may lead to the development of new therapeutics. Topics include the role of Ab toxicity, glial cells, and inflammation in Alzheimer's disease; the formation of abnormal protein fragments across several diseases, the impact of dopamine and mitochondrial dysfunction on neurodegeneration; and the potential of genetics to identify the molecular mechanisms of neurodegenerative diseases. Authoritative and insightful, Molecular Mechanisms of Neurodegenerative Diseases synthesizes the novel ideas and concepts now emerging to create a fresh understanding of neurodegenerative disorders, one that promises to lead to powerful new therapies that prevent, delay the onset, slow the progression, or even cure these cruel diseases.

• Author : Dr. Daniel Siegel, M.D.
• Publisher : Penguin
• Release Date : 2021-10-05
• Total pages : 176
• ISBN : 9781101993064
• File Size : 36,9 Mb
• Total Download : 366
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Download Becoming Aware in PDF, Epub, and Kindle

This hands-on user’s guide to the groundbreaking Wheel of Awareness meditation practice featured in the New York Times bestseller Aware takes readers step-by-step through a twenty-one-day journey to discover what it means to be truly present and aware in our daily lives. In today’s increasingly fast-paced world it can be difficult to find moments to catch your breath, regain inner balance, and just . . . be. This simple yet profound guide shows readers how to strengthen their minds by learning to focus attention, open awareness, and develop a positive state of mind—the three pillars of mindfulness practice that research shows lead to greater physical and mental well-being. Psychiatrist and cofounder of the Mindsight Institute, Daniel J. Siegel, M.D., created the science-grounded meditation practice called the Wheel of Awareness to unlock the power of the brain to integrate its many functions and develop internal resources that lead to an enduring sense of calm and quiet. Packed with guided meditation instructions, practical exercises, and everyday tools and techniques, Becoming Aware meets readers where they are and offers a simple program to enhance our inner sense of clarity and even our interpersonal well-being.

• Author : Dr Sarah McKay
• Publisher : Hachette Australia
• Release Date : 2018-03-27
• Total pages : 320
• ISBN : 9780733638534
• File Size : 42,6 Mb
• Total Download : 663
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Download The Women's Brain Book in PDF, Epub, and Kindle

For women, understanding how the brain works during the key stages of life - in utero, childhood, puberty and adolescence, pregnancy and motherhood, menopause and old age - is essential to their health. Dr Sarah McKay is a neuroscientist who knows everything worth knowing about women's brains, and shares it in this fascinating, essential book. This is not a book about the differences between male and female brains, nor a book using neuroscience to explain gender-specific behaviours, the 'battle of the sexes' or 'Mars-Venus' stereotypes. This is a book about what happens inside the brains and bodies of women as they move through the phases of life, and the unique - and often misunderstood - effects of female biology and hormones. Dr McKay give insights into brain development during infancy, childhood and the teenage years (including the onset of puberty) and also takes a look at mental health as well as the ageing brain. The book weaves together findings from the research lab, case studies and interviews with neuroscientists and other researchers working in the disciplines of neuroendocrinology, brain development, brain health and ageing. This comprehensive guide explores the brain during significant life stages, including: In utero Childhood Puberty The Menstrual Cycle The Teenage Brain Depression and Anxiety Pregnancy and Motherhood Menopause The Ageing Brain

• Author : Alexei Verkhratsky,Vladimir Parpura
• Publisher : Biota Publishing
• Release Date : 2015-03-01
• Total pages : 174
• ISBN : 9781615046737
• File Size : 35,6 Mb
• Total Download : 827
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Download Physiology of Astroglia in PDF, Epub, and Kindle

Astrocytes can be defined as the glia inhabiting the nervous system with the main function in the maintenance of nervous tissue homeostasis. Classified into several types according to their morphological appearance, many of astrocytes form a reticular structure known as astroglial syncytium, owing to their coupling via intercellular channels organized into gap junctions. Not only do astrocytes establish such homocellular contacts, but they also engage in intimate heterocellular interactions with neurons, most notably at synaptic sites. As synaptic structures house the very core of information transfer and processing in the nervous system, astroglial perisynaptic positioning assures that these glial cells can nourish neurons and establish bidirectional communication with them, functions outlined in the concepts of the astrocytic cradle and multi-partite synapse, respectively. Astrocytes possess a rich assortment of ligand receptors, ion and water channels, and ion and ligand transporters, which collectively contribute to astrocytic control of homeostasis and excitability. Astroglia control glutamate and adenosine homeostasis to exert modulatory actions affecting the real-time operation of synapses. Fluctuations of intracellular calcium can lead to the release of various chemical transmitters from astrocytes through a process termed gliotransmission. Sodium fluctuations are closely associated to those of calcium with both dynamic events interfacing signaling and metabolism. Astrocytes appear fully integrated into the brain cellular circuitry, being an indispensable part of neural networks.

• Author : Alexei Verkhratsky,Arthur Butt
• Publisher : John Wiley & Sons
• Release Date : 2007-08-20
• Total pages : 230
• ISBN : 0470513071
• File Size : 16,5 Mb
• Total Download : 846
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Download Glial Neurobiology in PDF, Epub, and Kindle

"This volume is a very valuable and much needed contribution." –Quarterly Review of Biology AT LAST - A comprehensive, accessible textbook on glial neurobiology! Glial cells are the most numerous cells in the human brain but for many years have attracted little scientific attention. Neurophysiologists concentrated their research efforts instead, on neurones and neuronal networks because it was thought that they were the key elements responsible for higher brain function. Recent advances, however, indicate this isn’t exactly the case. Not only are astroglial cells the stem elements from which neurones are born, but they also control the development, functional activity and death of neuronal circuits. These ground-breaking developments have revolutionized our understanding of the human brain and the complex interrelationship of glial and neuronal networks in health and disease. Features of this book: an accessible introduction to glial neurobiology including an overview of glial cell function and its active role in neural processes, brain function and nervous system pathology an exploration of all the major types of glial cells including: the astrocytes, oligodendrocytes and microglia of the ACNS and Schwann cells of the peripheral nervous system; the book also presents a broad overview of glial receptors and ion channels an investigation into the role of glial cells in various types of brain diseases including stroke, neurodegenerative diseases such as Alzheimer's, Parkinson's and Alexander's disease, brain oedema, multiple sclerosis and many more a wealth of illustrations, including unique images from the authors' own libraries of images, describing the main features of glial cells Written by two leading experts in the field, Glial Neurobiology provides a concise, authoritative introduction to glial physiology and pathology for undergraduate/postgraduate neuroscience, biomedical, medical, pharmacy, pharmacology, and neurology, neurosurgery and physiology students. It is also an invaluable resource for researchers in neuroscience, physiology, pharmacology and pharmaceutics.

• Author : John B. Arden
• Publisher : John Wiley & Sons
• Release Date : 2010-03-22
• Total pages : 256
• ISBN : 9780470487297
• File Size : 15,5 Mb
• Total Download : 669
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Download Rewire Your Brain in PDF, Epub, and Kindle

How to rewire your brain to improve virtually every aspect of your life-based on the latest research in neuroscience and psychology on neuroplasticity and evidence-based practices Not long ago, it was thought that the brain you were born with was the brain you would die with, and that the brain cells you had at birth were the most you would ever possess. Your brain was thought to be “hardwired” to function in predetermined ways. It turns out that's not true. Your brain is not hardwired, it's "softwired" by experience. This book shows you how you can rewire parts of the brain to feel more positive about your life, remain calm during stressful times, and improve your social relationships. Written by a leader in the field of Brain-Based Therapy, it teaches you how to activate the parts of your brain that have been underactivated and calm down those areas that have been hyperactivated so that you feel positive about your life and remain calm during stressful times. You will also learn to improve your memory, boost your mood, have better relationships, and get a good night sleep. Reveals how cutting-edge developments in neuroscience, and evidence-based practices can be used to improve your everyday life Other titles by Dr. Arden include: Brain-Based Therapy-Adult, Brain-Based Therapy-Child, Improving Your Memory For Dummies and Heal Your Anxiety Workbook Dr. Arden is a leader in integrating the new developments in neuroscience with psychotherapy and Director of Training in Mental Health for Kaiser Permanente for the Northern California Region Explaining exciting new developments in neuroscience and their applications to daily living, Rewire Your Brain will guide you through the process of changing your brain so you can change your life and be free of self-imposed limitations.

• Author : Peter S. Ungar
• Publisher : JHU Press
• Release Date : 2010-10-01
• Total pages : 320
• ISBN : 0801899516
• File Size : 14,9 Mb
• Total Download : 591
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Download Mammal Teeth in PDF, Epub, and Kindle

His book is a must-read for paleontologists, mammalogists, and anthropologists.

• Author : Dr. Daniel Siegel, M.D.
• Publisher : Penguin
• Release Date : 2018-08-21
• Total pages : 400
• ISBN : 9780143111788
• File Size : 17,8 Mb
• Total Download : 113
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Download Aware in PDF, Epub, and Kindle

New York Times bestseller · This groundbreaking new book from New York Times bestselling author Daniel J. Siegel, M.D., introduces readers to his pioneering, science-based meditation practice. Aware provides practical instruction for mastering the Wheel of Awareness, a life-changing tool for cultivating more focus, presence, and peace in one's day-to-day life. An in-depth look at the science that underlies meditation's effectiveness, this book teaches readers how to harness the power of the principle "Where attention goes, neural firing flows, and neural connection grows." Siegel reveals how developing a Wheel of Awareness practice to focus attention, open awareness, and cultivate kind intention can literally help you grow a healthier brain and reduce fear, anxiety, and stress in your life. Whether you have no experience with a reflective practice or are an experienced practitioner, Aware is a hands-on guide that will enable you to become more focused and present, as well as more energized and emotionally resilient in the face of stress and the everyday challenges life throws your way.

• Author : George Mather
• Publisher : Psychology Press
• Release Date : 2016-08-12
• Total pages : 830
• ISBN : 9781317372547
• File Size : 39,6 Mb
• Total Download : 227
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Download Foundations of Sensation and Perception in PDF, Epub, and Kindle

Do you wonder how movies – sequences of static frames – appear to move, or why 3-D films look different from traditional movies? Why does ventriloquism work, and why can airliner flights make you feel disoriented? The answers to these and other questions about the human senses can be found within the pages of Foundations of Sensation and Perception. This third edition maintains the standard for clarity and accessibility combined with rigor which was set in previous editions, making it suitable for a wide range of students. As in the previous editions, the early chapters allow students to grasp fundamental principles in relation to the relatively simple sensory systems (smell, taste, touch and balance) before moving on to more complex material in hearing and vision. The text has been extensively updated, and this new edition includes: a new chapter devoted to attention and perception over 200 new references over 30 new figures and improved, more colorful, visual presentation a new companion website with a range of resources for students and lecturers The book contains a range of pedagogical features, including tutorial sections at the end of each chapter. This distinctive feature introduces areas of the subject which are rarely included in student texts, but are crucial for establishing a firm foundation of knowledge. Some tutorials are devoted to more advanced and technical topics (optics, light measurement, Bayesian inference), but treated in an accessible manner, while others cover topics a little outside of the mainstream (music perception, consciousness, visual art). Foundations of Sensation and Perception will enable the reader to achieve a firm grasp of current knowledge concerning the processes that underlie our perception of the world and will be an invaluable resource for those studying psychology, neuroscience, and related disciplines.

• Author : Mark Seidenberg
• Publisher : Basic Books
• Release Date : 2017-01-03
• Total pages : 384
• ISBN : 9780465080656
• File Size : 27,8 Mb
• Total Download : 888
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Download Language at the Speed of Sight in PDF, Epub, and Kindle

In this "important and alarming" book, see why so many American students are falling behind in their reading skills while others around the world excel (New York Times). In 2011, when an international survey reported that students in Shanghai dramatically outperformed American students in reading, math, and science, President Obama declared it a "Sputnik moment": a wake-up call about the dismal state of American education. Little has changed, however, since then: over half of our children still read at a basic level and few become highly proficient. Many American children and adults are not functionally literate, with serious consequences. Poor readers are more likely to drop out of the educational system and as adults are unable to fully participate in the workforce, adequately manage their own health care, or advance their children's education. In Language at the Speed of Sight, internationally renowned cognitive scientist Mark Seidenberg reveals the underexplored science of reading, which spans cognitive science, neurobiology, and linguistics. As Seidenberg shows, the disconnect between science and education is a major factor in America's chronic underachievement. How we teach reading places many children at risk of failure, discriminates against poorer kids, and discourages even those who could have become more successful readers. Children aren't taught basic print skills because educators cling to the disproved theory that good readers guess the words in texts, a strategy that encourages skimming instead of close reading. Interventions for children with reading disabilities are delayed because parents are mistakenly told their kids will catch up if they work harder. Learning to read is more difficult for children who speak a minority dialect in the home, but that is not reflected in classroom practices. By building on science's insights, we can improve how our children read, and take real steps toward solving the inequality that illiteracy breeds. Both an expert look at our relationship with the written word and a rousing call to action, Language at the Speed of Sight is essential for parents, educators, policy makers, and all others who want to understand why so many fail to read, and how to change that.

• Author : J. Andrew Armour,Jeffrey L. Ardell
• Publisher : Oxford University Press
• Release Date : 2004-05-06
• Total pages : 492
• ISBN : 0199775192
• File Size : 32,8 Mb
• Total Download : 298
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Download Basic and Clinical Neurocardiology in PDF, Epub, and Kindle

The progression of heart disease is associated with changes in the neurohumoral mechanisms that control cardiac function. The degree to which this neurohumoral remodeling occurs, even before overt signs of cardiac disease become manifest, is important for prognosis. To determine why some patients experience sudden death while others sustain life in the presence of severely compromised cardiac function, the neuronal control of cardiac electrical and mechanical events must be considered. Starting at the level of individual neurons and building upwards, this book describes the synergistic interactions that occur among intrathoracic and CNS feedback loops to permit precise control of regional cardiac behavior. On this basic science foundation, subsequent clinical chapters explore the remodeling that occurs in this system with aging, with the evolution of specific cardiac pathologies, and with the psychological concomitants of heart disease. Most importantly, these chapters provide unique insights into how specific therapies like beta-andrenergic receptor blockade not only affect cardiomyocytes directly but also mitigate the adverse neurohumoral changes that accompany disease processes, such as heart failure and essential hypertension. The paradigm advanced in this volume is that heart disease is a multifaceted phenomenon involving the interplay of neurohumoral, cardiomyocyte and structural elements, each of which depends on the other. With our cumulative understanding of these interdependent processes, new avenues for time-appropriate, targeted methods of treating heart diseases can be developed.

• Author : Leonard Mlodinow
• Publisher : Penguin UK
• Release Date : 2022-01-04
• Total pages : 265
• ISBN : 9780241391556
• File Size : 34,5 Mb
• Total Download : 621
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Download Emotional in PDF, Epub, and Kindle

'Both a brilliant scholar and a great writer, Leonard Mlodinow guides us through the fascinating science of what we feel, and why - and what we can do about it. I learned a lot from this wonderful book' Rick Hanson We've been told we need to master our emotions and think rationally to succeed. But cutting-edge science shows that feelings are every bit as important to our success as thinking. You make hundreds of decisions every day, from what to eat for breakfast to how to influence people, and not one of them could be made without the essential component of emotion. It has long been held that thinking and feeling are separate and opposing forces in our behaviour. But as best-selling author Leonard Mlodinow tells us, extraordinary advances in psychology and neuroscience have proven that emotions are as critical to our well-being as thinking. How can you connect better with others? How can you improve your relationship to frustration, fear, and anxiety? What can you do to live a happier life? The answers lie in understanding emotions. Taking us on a journey from the labs of pioneering scientists to real-world scenarios that have flirted with disaster, Mlodinow shows us how our emotions help, why they sometimes hurt, and what we can make of the difference. Cutting-edge research and deep insights into our evolution, biology, and neuroscience promise to help us understand our emotions better and maximize their benefits. Told with characteristic clarity and fascinating stories, Mlodinow's exploration of the new science of feelings is an essential guide to making the most of one of nature's greatest gifts to us.

• Author : Stuart Brown M.D.,Christopher Vaughan
• Publisher : Penguin
• Release Date : 2009-03-05
• Total pages : 240
• ISBN : 9781101016237
• File Size : 16,9 Mb
• Total Download : 974
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Download Play in PDF, Epub, and Kindle

From a leading expert, a groundbreaking book on the science of play, and its essential role in fueling our happiness and intelligence throughout our lives We've all seen the happiness on the face of a child while playing in the school yard. Or the blissful abandon of a golden retriever racing across a lawn. This is the joy of play. By definition, play is purposeless, all-consuming, and fun. But as Dr. Stuart Brown illustrates, play is anything but trivial. It is a biological drive as integral to our health as sleep or nutrition. We are designed by nature to flourish through play. Dr. Brown has spent his career studying animal behavior and conducting more than six-thousand "play histories" of humans from all walks of life-from serial murderers to Nobel Prize winners. Backed by the latest research, Play explains why play is essential to our social skills, adaptability, intelligence, creativity, ability to problem solve and more. Particularly in tough times, we need to play more than ever, as it's the very means by which we prepare for the unexpected, search out new solutions, and remain optimistic. A fascinating blend of cutting-edge neuroscience, biology, psychology, social science, and inspiring human stories of the transformative power of play, this book proves why play just might be the most important work we can ever do.

• Author : Kate E. Reynolds
• Publisher : Jessica Kingsley Publishers
• Release Date : 2015-01-21
• Total pages : 32
• ISBN : 9780857009371
• File Size : 19,9 Mb
• Total Download : 695
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Download What's Happening to Ellie? in PDF, Epub, and Kindle

Ellie notices that her body is changing. Hair is growing in new places and there are other changes happening too. Ellie's mum helps her understand that she has started growing into a woman. Following Ellie as she begins to notice changes to her body, this simple resource helps parents and carers teach girls with autism and related conditions about puberty. It covers all the changes that they will experience, both emotional such as new feelings and physical such as periods. This fully illustrated positive and entertaining book provides the perfect opportunity to talk about puberty with girls and young women with autism or related conditions.