Precision Medicine And Neurodegenerative Disorders

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Precision Medicine in Neurodegenerative Disorders

Precision Medicine in Neurodegenerative Disorders
  • Author : Anonim
  • Publisher : Elsevier
  • Release Date : 2023-05-01
  • Total pages : 0
  • ISBN : 9780323900645
  • File Size : 37,5 Mb
  • Total Download : 443
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Precision Medicine in Neurodegenerative Disorders, Part One, Volume 192 deals with the "Why" in the approach to slow the progression of those suffering from diseases of accelerated brain aging. Matching a biology-correcting therapy with those biologically suitable to benefit from such therapy represents the vision and mission of precision medicine, the highest level of personalized medicine. This first Handbook of Clinical Neurology volume is intended to provide a scholarly background on the framework, basic science, and conceptual pitfalls related to disease-modifying efforts in Parkinson, Alzheimer, and other neurodegenerative disorders. Among the topics covered are the different models of precision medicine, the lumping-versus-splitting tension in biomarker development and therapeutics, and the rationale for replacing the convergence of the prevailing autopsy-based nosology of neurodegenerative diseases with the divergence of a systems biology approach to human diseases. Specific chapters are dedicated to the promise of genetic subtypes and the lessons in disease modification offered by the fields of oncology and cystic fibrosis that can be adapted to the field of neurodegeneration. Summarizes theory and research on precision medicine in neurodegenerative disorders Covers basic biology, clinical trials and therapeutics Includes disease mechanisms, genetic subtypes, and more

Precision Medicine in Neurodegenerative Disorders

Precision Medicine in Neurodegenerative Disorders
  • Author : Anonim
  • Publisher : Elsevier
  • Release Date : 2023-05-01
  • Total pages : 0
  • ISBN : 9780323900652
  • File Size : 31,9 Mb
  • Total Download : 531
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Precision Medicine in Neurodegenerative Disorders, Part Two, Volume 193 deals with the "How" in the reconfiguration of our approach to slow the progression of those suffering from diseases of accelerated brain aging. This second Handbook of Clinical Neurology volume offers a rethinking of the animal models on which therapies are tested; outlines the progress and expected changes in biological subtyping efforts using lysosomal, endosomal, mitochondrial, immune dysregulation, and inflammatory mechanisms of disease pathophysiology; and the growing role of microbiome in shaping disease and as a future target of therapeutic efforts. The volume separates the potentially disease-modifying neurorescue and neurorestoration, (e.g., gene therapy and cell replacement therapy) from true precision medicine –matching the biology of those affected with the mechanism of the intervention of interest. Specific chapters are dedicated to the promise and challenges of extracellular vesicles for both diagnosis and treatment, the growing application of digital measures and other evaluations of clinical response, the nuts and bolts of novel adaptive clinical trial designs, and the regulatory changes needed to facilitate drug development for disease-modification purposes. Summarizes theory and research on precision medicine in neurodegenerative disorders Covers basic biology, clinical trials and therapeutics Includes disease mechanisms, genetic subtypes, and more

Epigenetics in Precision Medicine

Epigenetics in Precision Medicine
  • Author : Jose Luis Garcia-Gimenez
  • Publisher : Elsevier
  • Release Date : 2021-11-22
  • Total pages : 614
  • ISBN : 9780323858052
  • File Size : 23,5 Mb
  • Total Download : 150
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In recent years, knowledge of epigenetic mechanisms underlying disease onset and progression has proven crucial for the development of novel early diagnosis and prognosis biomarkers for patient stratification and precision medicine. Epigenetics in Precision Medicine, a new volume in the Translational Epigenetics series, provides a thorough discussion and overview of current developments in clinical epigenetics with special emphasis on epigenetic biomarkers that can be used for clinical diagnosis, prognosis, patient stratification, and treatment monitoring. Disease types discussed include cancer, metabolic disorders, neurodegenerative diseases, bone disease, and immune-related disorders. The book examines the challenges of advancing epigenetics research and translating findings to the clinic and drug discovery in each of these areas, as well as current solutions; chapter authors discuss how to leverage epigenomic technologies, applications, and tools, such as next-generation sequencing, to discover new epigenetic biomarkers in disease and drug studies. Epigenetics in Precision Medicine focuses on complex epigenetic mechanisms in several pathologies, and explores how epigenetics can power the advance of precision medicine, not only by improving in vitro diagnostic and prognostic tools, but by providing new therapeutic approaches to treat human disease. Provides a thorough grounding in epigenetics-driven precision medicine, with emphasis on developing and implementing early diagnosis and prognosis biomarkers, and supporting patient stratification Empowers researchers and clinicians to incorporate epigenetics in new disease research, drug discovery, and clinical practice Features chapter contributions from international leaders in the field

Personalised Medicine

Personalised Medicine
  • Author : Sherif El-Khamisy
  • Publisher : Springer
  • Release Date : 2017-08-24
  • Total pages : 260
  • ISBN : 9783319607337
  • File Size : 35,8 Mb
  • Total Download : 151
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The mammalian genome is constantly challenged by exogenous and endogenous threats. Although much is known about the mechanisms that maintain genome integrity, little is known about the applications of this knowledge to combat human disease. The past 20 years has witnessed extensive research and progress in this area and scientists started to design new therapies harnessing individual genetic differences among patients to combat degenerative disorders and cancer. We summarize these advancements and discuss perspectives for the future of personalized medicine.

Molecular Imaging and Precision Medicine, Part 1, An Issue of PET Clinics, E-Book

Molecular Imaging and Precision Medicine, Part 1, An Issue of PET Clinics, E-Book
  • Author : Rathan M. Subramaniam
  • Publisher : Elsevier Health Sciences
  • Release Date : 2016-11-21
  • Total pages : 229
  • ISBN : 9780323482868
  • File Size : 21,7 Mb
  • Total Download : 528
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This issue of PET Clinics focuses on Molecular Imaging and Precision Medicine, Part 1, and is edited by Dr. Rathan Subramaniam. Articles will include: What is Precision Medicine?; Molecular Imaging and Precision Medicine in Head and Neck Cancer; Therapy Response Assessment using Molecular Imaging and Precision Medicine; Molecular Imaging and Precision Medicine in Breast Cancer; Molecular Imaging and Precision Medicine in Dementia and Movement Disorders; Molecular Imaging and Precision Medicine in Prostate Cancer; Molecular Imaging and Precision Medicine in Lymphoma; Radionucleide Therapies in Molecular Imaging and Precision Medicine, PET based Precision Medicine in Thyroid Carcinoma; Molecular Imaging and Precision Medicine in Lung Cancer, and more!

Precision Medicine in Cancers and Non-Communicable Diseases

Precision Medicine in Cancers and Non-Communicable Diseases
  • Author : Debmalya Barh
  • Publisher : CRC Press
  • Release Date : 2018-09-03
  • Total pages : 326
  • ISBN : 9781498775625
  • File Size : 35,5 Mb
  • Total Download : 361
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The availability of human genome, large amount of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the era of clinical practice of "Precision Medicine". This book aims to provide a readily available resource on all the important developments achieved so far in the field of oncology. All recent developments have been explained along with epidemiology, technologies and approaches to manage the included diseases. Therefore, readers will get the up to date information on the next-generation approach in tackling all kinds of cancer. Key Features • Presents the latest trend of cancer management based on precision/predictive medicine approach • Reviews the latest and up to date literature in the field of Precision Medicine • Highlights the next generation approach in tackling malignant diseases • Discusses how a life-threatening disease like cancer can be managed with the help of Precision Medicine • Encapsulates a global prospective

Reviews on Biomarker Studies in Psychiatric and Neurodegenerative Disorders

Reviews on Biomarker Studies in Psychiatric and Neurodegenerative Disorders
  • Author : Paul C. Guest
  • Publisher : Springer
  • Release Date : 2019-02-12
  • Total pages : 328
  • ISBN : 9783030055424
  • File Size : 31,6 Mb
  • Total Download : 222
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This book includes a series of reviews on general aspects of biomarker use in the study of psychiatric and neurodegenerative diseases and the development of medications involved in their treatment. It describes the pros and cons of the various approaches and covers the successes and failures in this research field. It is only by a thorough understanding of the shortcomings that progress can be made. The overall goal is to facilitate the understanding and treatment of these disorders, by providing a viable mechanism of catching up with other areas of modern medicine, such as diabetes and heart disease. Finally, it is anticipated that the development and application of valid biomarker tests and the leveraging of novel drug targets will help the fields of psychiatry on neurodegenerative disorders move into the area of personalized medicine where the right patients can receive the right medication at the right time for the best possible outcome.

Pathology, Prevention and Therapeutics of Neurodegenerative Disease

Pathology, Prevention and Therapeutics of Neurodegenerative Disease
  • Author : Sarika Singh,Neeraj Joshi
  • Publisher : Springer
  • Release Date : 2018-09-24
  • Total pages : 301
  • ISBN : 9789811309441
  • File Size : 43,5 Mb
  • Total Download : 336
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This book, written by a leading panel of experts in the field of neurosciences, provides a comprehensive overview of the pathology of neurodegenerative diseases as well as the preventive measures. Prevention is important due to the lack of early diagnostic markers and the limitations/ problems of treating neurodegenerative diseases

TDP-43 and Neurodegeneration

TDP-43 and Neurodegeneration
  • Author : Vijay Kumar,Manoj Kumar Jaiswal
  • Publisher : Academic Press
  • Release Date : 2021-10-23
  • Total pages : 270
  • ISBN : 9780128204405
  • File Size : 46,5 Mb
  • Total Download : 535
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Aggregates of the TAR DNA binding protein 43 (TDP-43), are hallmark features of the neurodegenerative diseases Amyotrophic Lateral Sclerosis (ALS) and frontotemporal dementia (FTD), with overlapping clinical, genetic and pathological features. TDP-43 and Neurodegeneration: From Bench to Bedside summarizes new findings in TDP-43 pathobiology and proteinopathies. The book summarizes TDP-43’s structure, function, biology, misfolding, aggregation, pathogenesis and therapeutics. It includes autophagy-mediated therapy, role of stress granule, novel genetic, cell culture-based models, systems biology for precision medicine, development of stem cells and mechanism-based therapies that can target ALS and other related neurodegenerative diseases. This book is written for neuroscientists, neurologists, clinicians, advanced graduate students, drug discovery researchers, as well as cellular and molecular biologists involved in ALS, motor neuron disease (MND) and other neurodegenerative disorders. Reviews TDP-43 structure, folding, function, and pathology Identifies TDP-43 role in ALS, FTP, and other neurodegenerative diseases Presents a systems and precision biology perspective of TDP-43 Discusses therapeutics of TDP-43 proteinopathies Translates bench research to application bedside

Parkin...ss..oo..nn

Parkin...ss..oo..nn
  • Author : Alain L Fymat
  • Publisher : Unknown
  • Release Date : 2020-04-06
  • Total pages : 258
  • ISBN : 0228828740
  • File Size : 53,5 Mb
  • Total Download : 188
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Despite decades of research, billions of dollars spent worldwide, the development of many drugs, many failed clinical trials, and the extensive publication of research and other articles on the subject, it is clear that our approach to solving Parkinson's disease is not really working. Indeed, presently, no drug can cure or stop this disease from progressing! What is happening? Like in the case of Alzheimer's and other neurodegenerative diseases, Dr. Fymat believes we got the cause all wrong and, instead, of remaining focused on the primary end-point of a cure, the emphasis had shifted to surrogate often uncorrelated, end-points. In this book, he elucidates the disease and attempts to reorient our approach along a path he is convinced will be more successful in leading us to a cure. He breaks down barriers to make research accessible and focuses on the important aspects of the underlying research. He distills this information and conveys to Parkinson's patients and their caregivers the results of research, including his own, on this devastating disease. He also reports on his breakthrough as to the underlying root cause of the disease, provides the outlines of his new approach, and even suggests the methodology to be followed.

The Right Therapy for Neurological Disorders

The Right Therapy for Neurological Disorders
  • Author : E. Beghi,G. Logroscino
  • Publisher : Karger Medical and Scientific Publishers
  • Release Date : 2016-07-26
  • Total pages : 168
  • ISBN : 9783318058659
  • File Size : 19,8 Mb
  • Total Download : 916
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Most neurological disorders are chronic and aging-related. With the increase of life expectancy their incidence and prevalence will grow in the decades to come, which in turn will increase the load on medical and social systems worldwide. There is thus a desperate need for successful preventive and therapeutic measures based on randomized clinical trials (RTCs) conducted by independent organizations. This book provides a compendium relating most of the principles of reliable RTCs to specific neurological diseases. Contributed by specialized neurologists, the articles touch on important aspects of RCTs with a clear critical approach, highlighting their limitations as well as giving recommendations for their planning and conducting to address the variable genotypic and phenotypic aspects of neurological conditions. Consideration is also given to combining the clinical impact of the study results with patients’ values and the interests of pharmaceutical companies. Neurologists involved in clinical trials will certainly benefit from this book, which should become a basic text for all neurological courses dealing with evidence-based neurology.

Diseases of the Nervous System

Diseases of the Nervous System
  • Author : Harald Sontheimer
  • Publisher : Elsevier
  • Release Date : 2021-05-20
  • Total pages : 500
  • ISBN : 9780128213964
  • File Size : 18,7 Mb
  • Total Download : 836
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The study of the brain continues to expand at a rapid pace providing fascinating insights into the basic mechanisms underlying nervous system illnesses. New tools, ranging from genome sequencing to non-invasive imaging, and research fueled by public and private investment in biomedical research has been transformative in our understanding of nervous system diseases and has led to an explosion of published primary research articles. Diseases of the Nervous System, Second Edition, summarizes the current state of basic and clinical knowledge for the most common neurological and neuropsychiatric conditions. In a systematic progression, each chapter covers either a single disease or a group of related disorders ranging from static insults to primary and secondary progressive neurodegenerative diseases, neurodevelopmental illnesses, illnesses resulting from nervous system infection and neuropsychiatric conditions. Chapters follow a common format and are stand-alone units, each covering disease history, clinical presentation, disease mechanisms and treatment protocols. Dr. Sontheimer also includes two chapters which discuss common concepts shared among the disorders and how new findings are being translated from the bench to the bedside. In a final chapter, he explains the most commonly used neuroscience jargon. The chapters address controversial issues in current day neuroscience research including translational research, drug discovery, ethical issues, and the promises of personalized medicine. This new edition features new chapters on Pain and Addiction to highlight the growing opioid crisis and the ethical issue of prescriptions drug abuse. This book provides an introduction for course adoption and an introductory tutorial for students, scholars, researchers and medical professionals interested in learning the state of the art concerning our understanding and treatment of diseases of the nervous system. Each chapter includes suggested further readings and/or journal club recommendations. 2016 PROSE Award winner of the Best Textbook Award in Biological and Life Sciences Provides a focused tutorial introduction to the core diseases of the nervous system Includes comprehensive introductions to Stroke, Epilepsy, Alzheimer's Disease, Parkinson's Disease, Huntington's Disease, ALS, Head and Spinal Cord Trauma, Multiple Sclerosis, Brain Tumors, Depression, Schizophrenia and many other diseases of the nervous system Covers more than 40 diseases from the foundational science to the best treatment protocols Includes discussions of translational research, drug discovery, personalized medicine, ethics, and neuroscience New Edition features two new chapters on Pain and Addiction

Precision Medicine in Cancers and Non-Communicable Diseases

Precision Medicine in Cancers and Non-Communicable Diseases
  • Author : Debmalya Barh
  • Publisher : CRC Press
  • Release Date : 2018-09-03
  • Total pages : 326
  • ISBN : 9781351650786
  • File Size : 26,9 Mb
  • Total Download : 439
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The availability of human genome, large amount of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the era of clinical practice of "Precision Medicine". This book aims to provide a readily available resource on all the important developments achieved so far in the field of oncology. All recent developments have been explained along with epidemiology, technologies and approaches to manage the included diseases. Therefore, readers will get the up to date information on the next-generation approach in tackling all kinds of cancer. Key Features • Presents the latest trend of cancer management based on precision/predictive medicine approach • Reviews the latest and up to date literature in the field of Precision Medicine • Highlights the next generation approach in tackling malignant diseases • Discusses how a life-threatening disease like cancer can be managed with the help of Precision Medicine • Encapsulates a global prospective

Handbook of Research on Critical Examinations of Neurodegenerative Disorders

Handbook of Research on Critical Examinations of Neurodegenerative Disorders
  • Author : Uddin, Md. Sahab,Amran, Md. Shah
  • Publisher : IGI Global
  • Release Date : 2018-07-31
  • Total pages : 597
  • ISBN : 9781522552833
  • File Size : 49,6 Mb
  • Total Download : 930
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Neurodegeneration is a key feature of several diseases that are referred to as neurodegenerative diseases. The process of neurodegeneration is not well-understood so the diseases that stem from it have, as yet, no cures. As such, studying the effects of these disorders can provide insight into the treatment, prevention, and future opportunities and challenges in this growing field. The Handbook of Research on Critical Examinations of Neurodegenerative Disorders is a critical scholarly resource that provides an extensive explanation of various neurodegenerative disorders based on existing studies to clarify etiology, pathological mechanisms, diagnosis, therapeutic interventions, as well as current status and future opportunities and challenges. Featuring coverage on a broad range of topics such as dementia, mitochondrial dysfunction, and risk factors, this book is geared towards neurobiologists, neuropsychologists, neurophysiologists, neuropathologists, medical professionals, academicians, and researchers seeking research on the complexity of neurodegenerative disorders.

Role of Inflammation in Neurodegenerative Diseases

Role of Inflammation in Neurodegenerative Diseases
  • Author : Maya Koronyo-Hamaoui,Sally Ann Frautschy,Jorge Ivan Alvarez
  • Publisher : Frontiers Media SA
  • Release Date : 2022-07-13
  • Total pages : 461
  • ISBN : 9782889765621
  • File Size : 39,7 Mb
  • Total Download : 591
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PDF book entitled Role of Inflammation in Neurodegenerative Diseases written by Maya Koronyo-Hamaoui,Sally Ann Frautschy,Jorge Ivan Alvarez and published by Frontiers Media SA which was released on 2022-07-13 with total hardcover pages 461, the book become popular and critical acclaim.

Sex and Gender Differences in Neurological Disease

Sex and Gender Differences in Neurological Disease
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2022-08-27
  • Total pages : 394
  • ISBN : 9780323915908
  • File Size : 21,9 Mb
  • Total Download : 425
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International Review on Neurobiology serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in International Review on Neurobiology serials Updated release includes the latest information on Sex and Gender Differences in Neurological Disease

Integrative Neuroscience and Personalized Medicine

Integrative Neuroscience and Personalized Medicine
  • Author : Evian Gordon,Stephen Koslow, PhD
  • Publisher : Oxford University Press
  • Release Date : 2011
  • Total pages : 346
  • ISBN : 9780195393804
  • File Size : 40,9 Mb
  • Total Download : 853
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This book takes an in depth and hard look at the current status and future direction of treatment predictive markers in Personalized Medicine for the brain from the perspectives of the researchers on the cutting edge and those involved in healthcare implementation. The contents provide a comprehensive text suitable as both a pithy introduction to and a clear summary of the "science to solutions" continuum in this developing field of Personalized Medicine and Integrative Neuroscience. The science includes both measures of genes using whole genome approaches and SNIPS as well as BRAINmarkers of direct brain function such as brain imaging, biophysical changes and objective cognitive and behavioral measurements. Personalized Medicine for Brain Disorders will soon be a reality using the comprehensive quantitative and standardized approaches to genomics, BRAINmarkers and cognitive function. Each chapter provides a review of recent relevant literature; show the solutions achieved through integrative neuroscience and applications in patient care thus providing a practical guide to the reader. The timeliness of this book's content is propitious providing bottom line information to educate practicing clinicians, health care workers and researchers, and also a pathway for undergraduate and graduates interested in further their understanding of and involvement in tailored personal solutions.

Textbook of Personalized Medicine

Textbook of Personalized Medicine
  • Author : Kewal K. Jain
  • Publisher : Humana Press
  • Release Date : 2015-03-17
  • Total pages : 732
  • ISBN : 9781493925537
  • File Size : 23,5 Mb
  • Total Download : 717
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Advances in the technology used in personalized medicine and increased applications for clinical use have created a need for this expansion and revision of Kewal K. Jain’s Textbook of Personalized Medicine. As the first definitive work on this topic, this book reviews the fundamentals and development of personalized medicine and subsequent adoptions of the concepts by the biopharmaceutical industry and the medical profession. It also discusses examples of applications in key therapeutic areas, as well as ethical and regulatory issues, providing a concise and comprehensive source of reference for those involved in healthcare management, planning and politics. Algorithms are included as a guide to those involved in the management of important diseases where decision-making is involved due to the multiple choices available. Textbook of Personalized Medicine, Second Edition will serve as a convenient source of information for physicians, scientists, decision makers in the biopharmaceutical and healthcare industries and interested members of the public.

Omics for Personalized Medicine

Omics for Personalized Medicine
  • Author : Debmalya Barh,Dipali Dhawan,Nirmal Kumar Ganguly
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-10-14
  • Total pages : 832
  • ISBN : 9788132211846
  • File Size : 52,8 Mb
  • Total Download : 876
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“Omics for Personalized Medicine” will give to its prospective readers the insight of both the current developments and the future potential of personalized medicine. The book brings into light how the pharmacogenomics and omics technologies are bringing a revolution in transforming the medicine and the health care sector for the better. Students of biomedical research and medicine along with medical professionals will benefit tremendously from the book by gaining from the diverse fields of knowledge of new age personalized medicine presented in the highly detailed chapters of the book. The book chapters are divided into two sections for convenient reading with the first section covering the general aspects of pharmaocogenomic technology that includes latest research and development in omics technologies. The first section also highlights the role of omics in modern clinical trials and even discusses the ethical consideration in pharmocogenomics. The second section is focusing on the development of personalized medicine in several areas of human health. The topics covered range from metabolic and neurological disorders to non-communicable as well as infectious diseases, and even explores the role of pharmacogenomics in cell therapy and transplantation technology. Thirty-four chapters of the book cover several aspects of pharmacogenomics and personalized medicine and have taken into consideration the varied interest of the readers from different fields of biomedical research and medicine. Advent of pharmacogenomics is the future of modern medicine, which has resulted from culmination of decades of research and now is showing the way forward. The book is an honest endeavour of researchers from all over the world to disseminate the latest knowledge and knowhow in personalized medicine to the community health researchers in particular and the educated public in general.

Neurogenetics

Neurogenetics
  • Author : Anonim
  • Publisher : Elsevier
  • Release Date : 2018-01-08
  • Total pages : 436
  • ISBN : 9780444632357
  • File Size : 30,8 Mb
  • Total Download : 667
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Genetic methodologies are having a significant impact on the study of neurological and psychiatric disorders. Using genetic science, researchers have identified over 200 genes that cause or contribute to neurological disorders. Still an evolving field of study, defining the relationship between genes and neurological and psychiatric disorders is evolving rapidly and expected to grow in scope as more disorders are linked to specific genetic markers. Part I covers basic genetic concepts and recurring biological themes, and begins the discussion of movement disorders and neurodevelopmental disorders, leading the way for Part II to cover a combination of neurological, neuromuscular, cerebrovascular, and psychiatric disorders. This volume in the Handbook of Clinical Neurology will provide a comprehensive introduction and reference on neurogenetics for the clinical practitioner and the research neurologist. Presents a comprehensive coverage of neurogenetics Details the latest science and impact on our understanding of neurological psychiatric disorders Provides a focused reference for clinical practitioners and the neuroscience/neurogenetics research community

P5 eHealth: An Agenda for the Health Technologies of the Future

P5 eHealth: An Agenda for the Health Technologies of the Future
  • Author : Gabriella Pravettoni,Stefano Triberti
  • Publisher : Springer Nature
  • Release Date : 2019-11-29
  • Total pages : 191
  • ISBN : 9783030279943
  • File Size : 53,5 Mb
  • Total Download : 781
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This open access volume focuses on the development of a P5 eHealth, or better, a methodological resource for developing the health technologies of the future, based on patients’ personal characteristics and needs as the fundamental guidelines for design. It provides practical guidelines and evidence based examples on how to design, implement, use and elevate new technologies for healthcare to support the management of incurable, chronic conditions. The volume further discusses the criticalities of eHealth, why it is difficult to employ eHealth from an organizational point of view or why patients do not always accept the technology, and how eHealth interventions can be improved in the future. By dealing with the state-of-the-art in eHealth technologies, this volume is of great interest to researchers in the field of physical and mental healthcare, psychologists, stakeholders and policymakers as well as technology developers working in the healthcare sector.