Polysaccharide Carriers For Drug Delivery

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• Author : Sabyasachi Maiti,Sougata Jana
• Publisher : Woodhead Publishing
• Release Date : 2019-06-14
• Total pages : 802
• ISBN : 9780081025543
• File Size : 46,8 Mb
• Total Download : 993
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Download Polysaccharide Carriers for Drug Delivery in PDF, Epub, and Kindle

Polysaccharide Carriers for Drug Delivery presents the latest information on the selection of safe materials. Due to reported safety profiles on polysaccharides; they have been the natural choice for investigation. A wide variety of drug delivery and biomedical systems have been studied, however, the related information either concept-wise or application-oriented is scattered, therefore becoming difficult for readers and researchers to digest in a concise manner. This gathering of information will help readers easily comprehend the subject matter. Focuses on biopolysaccharide-based, distinct approaches for drug delivery applications Illustrates new concepts and highlights future scope for clinical development Provides comprehensive, up-to-date information on different aspects of drug delivery technology

• Author : Md Saquib Hasnain,Amit Kumar Nayak
• Publisher : Academic Press
• Release Date : 2019-07-23
• Total pages : 654
• ISBN : 9780128170564
• File Size : 17,6 Mb
• Total Download : 755
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Download Natural Polysaccharides in Drug Delivery and Biomedical Applications in PDF, Epub, and Kindle

Natural Polysaccharides in Drug Delivery and Biomedical Applications provides a fundamental overview of natural polysaccharides, their sources, extraction methodologies, and characterizations. It covers specific natural polysaccharides and their effective application in drug delivery and biomedical use. Additionally, chapters in the book discuss key topics including the sources and extraction methodologies of natural polysaccharides, their role in tissue engineering applications, polysaccharide-based nanoparticles in biomedical applications, and their role in the delivery of anticancer drugs. Written by industry leaders and edited by experts, this book emphasizes recent advances made in the field. Natural Polysaccharides in Drug Delivery and Biomedical Applications provides academics, researchers, and pharmaceutical health care professionals with a comprehensive book on polysaccharides in pharmaceutical delivery process. Provides fundamental concepts of natural polysaccharides as it applies to the pharmaceutical, biomedical, and biotechnology industries Includes contributions from global leaders and experts from academia, industry, and regulatory agencies in the application of natural polysaccharides in pharmaceutical products and biomedical utilization Offers practical examples, illustrations, chemical structures, and research case studies to help explain natural polysaccharides concepts in drug delivery and biomedical applications

• Author : Jayachandran Venkatesan,Se-Kwon Kim,Sukumaran Anil,Rekha P. D
• Publisher : Elsevier
• Release Date : 2022-01-11
• Total pages : 690
• ISBN : 9780128223567
• File Size : 26,9 Mb
• Total Download : 541
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Download Polysaccharide Nanoparticles in PDF, Epub, and Kindle

Polysaccharide Nanoparticles: Preparation and Biomedical Applications provides detailed information on polysaccharides nanoparticles in terms of their synthesis and applications. Naturally occurring polysaccharides are widely used as food materials, particularly in Asia. Different kinds of polysaccharide materials are available from nature with various resources such as crustaceans and algae. The exploration and exploitation of polysaccharides nanoparticles from natural resource is at the heart of this book, which also explores the synthesis, preparation and applications of polysaccharides nanoparticles for tissue engineering and food applications. This is an important reference for materials scientists and bioengineers who are looking to gain a greater understanding on how polysaccharides nanoparticles are being used for a variety of biomedical applications. Explains the major synthesis and preparation methods of polysaccharide-based nanoparticles Demonstrates how polysaccharides nanoparticles are being used for a range of biomedical applications, including tissue engineering, drug delivery and biosensors Assesses the major challenges and risks of using polysaccharides nanoparticles safely and effectively

• Author : R. H. Marchessault,François Ravenelle,American Chemical Society. Meeting
• Publisher : Unknown
• Release Date : 2006
• Total pages : 394
• ISBN : UOM:39015064134227
• File Size : 36,9 Mb
• Total Download : 177
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Download Polysaccharides for Drug Delivery and Pharmaceutical Applications in PDF, Epub, and Kindle

Over the last decades we have seen the pharmaceutical industry grow at a tremendous rate. Along with the discoveries of drugs with novel and peculiar properties, the need for novel materials and methods to deliver them energized the field of drug delivery creating new opportunities for material scientists. Among those materials, the pharmaceutical industry has since the beginning relied on cellulose, the most abundant natural polymer on earth. Nowadays, many polysaccharides are used, modified and transformed to serve the pharmaceutical needs either as solubilizers, adhesives, carriers or active substances themselves. This book covers many of the polysaccharides used in the field, their sources, properties, preparation and mechanism of action

• Author : Amit Kumar Nayak,Md Saquib Hasnain
• Publisher : Academic Press
• Release Date : 2020-07-23
• Total pages : 434
• ISBN : 9780128176412
• File Size : 29,9 Mb
• Total Download : 495
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Download Alginates in Drug Delivery in PDF, Epub, and Kindle

Alginates in Drug Delivery explores the vital precepts, basic and fundamental aspects of alginates in pharmaceutical sciences, biopharmacology, and in the biotechnology industry. The use of natural polymers in healthcare applications over synthetic polymers is becoming more prevalent due to natural polymers’ biocompatibility, biodegradability, economic extraction and ready availability. To fully utilize and harness the potential of alginates, this book presents a thorough understanding of the synthesis, purification, and characterization of alginates and their derivative. This book collects, in a single volume, all relevant information on alginates in health care, including recent advances in the field. This is a highly useful resource for pharmaceutical scientists, health care professionals and regulatory scientists actively involved in the pharmaceutical product and process development of natural polymer containing drug delivery, as well as postgraduate students and postdoctoral research fellows in pharmaceutical sciences. Provides a single source on the complete alginate chemistry, collection, chemical modifications, characterization and applications in healthcare fields Includes high quality illustrations, along with practical examples and research case studies Contains contributions by global leaders and experts from academia, industry and regulatory agencies who are pioneers in the application of natural polysaccharides in diverse pharmaceutical fields

• Author : Jayachandran Venkatesan,Sukumaran Anil,Se-Kwon Kim
• Publisher : Elsevier
• Release Date : 2017-05-30
• Total pages : 408
• ISBN : 9780128098172
• File Size : 45,8 Mb
• Total Download : 534
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Download Seaweed Polysaccharides in PDF, Epub, and Kindle

Seaweed Polysaccharides: Isolation, Biological, and Biomedical Applications examines the isolation and characterization of algal biopolymers, including a range of new biological and biomedical applications. In recent years, significant developments have been made in algae-based polymers (commonly called polysaccharides), and in biomedical applications such as drug delivery, wound dressings, and tissue engineering. Demand for algae-based polymers is increasing and represent a potential—very inexpensive—resource for these applications. The structure and chemical modification of algal polymers are covered, as well as the biological properties of these materials – including antithrombic, anti-inflammatory, anticoagulant, and antiviral aspects. Toxicity of algal biopolymers is also covered. Finally, the book introduces and explains real world applications of algal-based biopolymers in biomedical applications, including tissue engineering, drug delivery, and biosensors. This is the first book to cover the extraction techniques, biomedical applications, and the economic perspective of seaweed polysaccharides. It is an essential text for researchers and industry professionals looking to work with this renewable resource. Provides comprehensive coverage of the research currently taking place in biomedical applications of algae biopolymers Includes practical guidance on the isolation, extraction, and characterization of polysaccharides from sustainable marine sources Covers the extraction techniques, biomedical applications, and economic outlook of seaweed polysaccharides

• Author : Raphael M. Ottenbrite,Sung Wan Kim
• Publisher : CRC Press
• Release Date : 2019-04-30
• Total pages : 281
• ISBN : 9780429524578
• File Size : 23,8 Mb
• Total Download : 642
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Download Polymeric Drugs and Drug Delivery Systems in PDF, Epub, and Kindle

Polymeric materials are now playing an increasingly important role in pharmaceuticals, as well as in sensing devices, in situ prostheses and probes, and microparticle diagnostic agents. This new volume consists of twenty-two recent research-based reports on the developments in these areas of pharmaceutical and biomaterials technology. The reports w

• Author : Sabyasachi Maiti,Sougata Jana
• Publisher : Woodhead Publishing
• Release Date : 2019-06-11
• Total pages : 526
• ISBN : 9780081025567
• File Size : 39,9 Mb
• Total Download : 276
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Download Functional Polysaccharides for Biomedical Applications in PDF, Epub, and Kindle

Functional Polysaccharides for Biomedical Applications examines the fundamentals and properties of these natural materials and their potential biomedical applications. With an emphasis on therapeutic and sensing applications, the book also reviews how polysaccharides can be modified for tissue engineering applications. Sections discuss the basics of polysaccharides, give an overview of the potential applications, look at novel materials and technologies for use in tissue regeneration and therapeutics, and detail current biomedical applications. With a strong focus on materials, engineering and applications, this book is a valuable resource for those with an interest in harnessing the biomedical potential of natural polymers. Describes strategies for developing polysaccharides-based biomedical devices Illustrates concepts and encompasses scope for clinical development Provides advanced and comprehensive information on biomedical constructs

• Author : Dr Helena S Azevedo,Dr João F Mano,Dr João Borges
• Publisher : Royal Society of Chemistry
• Release Date : 2021-06-11
• Total pages : 788
• ISBN : 9781788017572
• File Size : 54,6 Mb
• Total Download : 700
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Download Soft Matter for Biomedical Applications in PDF, Epub, and Kindle

Dynamic soft materials that have the ability to expand and contract, change stiffness, self-heal or dissolve in response to environmental changes, are of great interest in applications ranging from biosensing and drug delivery to soft robotics and tissue engineering. This book covers the state-of-the-art and current trends in the very active and exciting field of bioinspired soft matter, its fundamentals and comprehension from the structural-property point of view, as well as materials and cutting-edge technologies that enable their design, fabrication, advanced characterization and underpin their biomedical applications. The book contents are supported by illustrated examples, schemes, and figures, offering a comprehensive and thorough overview of key aspects of soft matter. The book will provide a trusted resource for undergraduate and graduate students and will extensively benefit researchers and professionals working across the fields of chemistry, biochemistry, polymer chemistry, materials science and engineering, nanosciences, nanotechnologies, nanomedicine, biomedical engineering and medical sciences.

• Author : K. L. Mittal,Inderbir Singh Bakshi,Jasjit Kaur Narang
• Publisher : John Wiley & Sons
• Release Date : 2020-06-16
• Total pages : 432
• ISBN : 9781119640196
• File Size : 22,5 Mb
• Total Download : 445
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Download Bioadhesives in Drug Delivery in PDF, Epub, and Kindle

This important and unique book comprises 12 chapters divided into three parts examining the fundamental aspects, bioadhesive formulations, and drug delivery applications. Understanding the phenomenon of bioadhesion i.e. its theories or mechanism(s) are of critical importance in developing optimum bioadhesive polymers (used in bioadhesives). Such bioadhesive polymers are the key for exhibiting the process of bioadhesion, controlled/sustained release of drugs, and drug targeting. The use of bioadhesives restricts the delivery system to the site of interest and thus offers a useful and efficient technique for targeting a drug to the desired location for a prolonged duration. This book addresses the various relevant aspects of bioadhesives in drug delivery in an easily accessible and unified manner. The book containing 12 chapters written by eminent researchers from many parts of the globe is divided into three parts: Part 1: Fundamental Aspects; Part 2: Bioadhesive Formulations; Part 3: Drug Delivery Applications. The topics covered include: Theories and mechanisms of bioadhesion; bioadhesive polymers for drug delivery applications; methods for characterization of bioadhesiveness of drug delivery systems; bioadhesive films and drug delivery applications; bioadhesive nanoparticles; bioadhesive hydrogels and applications; ocular biodhesive drug delivery systems; buccal bioadhesive drug delivery systems; gastrointestinal bioadhesive drug delivery systems; nasal bioadhesive drug delivery systems; vaginal drug delivery systems; pulmonary bioadhesive drug delivery systems.

• Author : Abbass A. Hashim
• Publisher : BoD – Books on Demand
• Release Date : 2012-05-16
• Total pages : 556
• ISBN : 9789535106159
• File Size : 47,7 Mb
• Total Download : 585
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Download The Delivery of Nanoparticles in PDF, Epub, and Kindle

Nanoparticle is a general challenge for today's technology and the near future observations of science. Nanoparticles cover mostly all types of sciences and manufacturing technologies. The properties of this particle are flying over today scientific barriers and have passed the limitations of conventional sciences. This is the reason why nanoparticles have been evaluated for the use in many fields. InTech publisher and the contributing authors of this book in nanoparticles are all overconfident to invite all scientists to read this new book. The book's potential was held until it was approached by the art of exploring the most advanced research in the field of nano-scale particles, preparation techniques and the way of reaching their destination. 25 reputable chapters were framed in this book and there were alienated into four altered sections; Toxic Nanoparticles, Drug Nanoparticles, Biological Activities and Nano-Technology.

• Author : Amit Kumar Nayak,Md Saquib Hasnain
• Publisher : Academic Press
• Release Date : 2022-09-23
• Total pages : 416
• ISBN : 9780128212875
• File Size : 27,9 Mb
• Total Download : 579
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Download Tailor-Made Polysaccharides in Drug Delivery in PDF, Epub, and Kindle

Tailor-Made Polysaccharides in Drug Delivery provides extensive details on all the vital precepts, basics and fundamental aspects of tailored polysaccharides in the pharmaceutical and biotechnological industry for understanding and developing high quality products. The book offers a comprehensive resource to understand the potential of the materials in forming new drug delivery methods. It will be useful to pharmaceutical scientists, chemical engineers, and regulatory scientists and students actively involved in pharmaceutical product and process development of tailored-made polysaccharides in drug delivery applications. The utilization of natural polymeric excipients in numerous healthcare applications demand the replacement of the synthetic polymers with the natural ones due to their biocompatibility, biodegradability, economic extraction and readily availability. The reality behind the rise in importance of these natural materials is that these sources are renewable if grown in a sustainable means and they can tender incessant supply of raw materials. Amongst these natural polymers, polysaccharides are considered as excellent excipients because of its non-toxic, stable, biodegradable properties. Several research innovations have been made on applications of polysaccharides in drug delivery. Provides methodologies for the design, development and selection of tailor-made, natural polysaccharides in drug delivery for particular therapeutic applications Includes illustrations that demonstrate the mechanism of biological interaction of tailor-made polysaccharides Discusses the regulatory aspects and demonstrates the clinical efficacy of tailor-made polysaccharides

• Author : Elia Bari,Sara Perteghella,Maria Luisa Torre
• Publisher : Royal Society of Chemistry
• Release Date : 2020-10-05
• Total pages : 225
• ISBN : 9781839162671
• File Size : 20,6 Mb
• Total Download : 390
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Download Silk-based Drug Delivery Systems in PDF, Epub, and Kindle

Silk proteins show excellent biocompatibility, controllable biodegradability and non-immunogenicity, and as such are studied extensively worldwide for biomedical applications. In particular, there is increasing interest in their use for drug delivery systems. This focussed book on silk proteins for drug delivery systems, delves into a key emerging area to outline the concepts and define the field. Covering spider silk and silk worm cocoons, the editors elucidate the extraction, structure and properties of silk sericin and silk fibroin. Showing how these proteins are employed in micro and nano drug delivery systems, their use in pre-clinical and clinical trials, and closing with chapter on sustainability- driven innovation in the pharma industry, this book is ideal for graduates and researchers in biomaterials science and pharmaceutical science.

• Author : Prof. (Dr.) Nirmal K. Patel,Savan H. Patel
• Publisher : GRIN Verlag
• Release Date : 2023-01-09
• Total pages : 255
• ISBN : 9783346788252
• File Size : 34,9 Mb
• Total Download : 817
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Download Synthesis and characterization of drug carrier based on polysaccharides in PDF, Epub, and Kindle

Doctoral Thesis / Dissertation from the year 2022 in the subject Chemistry - Other, , language: English, abstract: The title of this thesis “Synthesis and Characterization of Drug Carrier Based on Polysaccharides” clearly reflects the objective, which is an approach towards preparation of excipients, defined as ‘the substance used as a medium for giving a medicament’, that is to say with simply the functions of an inert support of the active principle or principles. Okra gum, obtained from the fruits of Hibiscus esculents, is a polysaccharide consisting of D-galactose, L-rhamnose and L-galacturonic acid. It is used as a binder. In studies okra gum has been evaluated as a binder in paracetamol tablet formulations. These formulations containing okra gum as a binder showed a faster onset and higher amount of plastic deformation than those containing gelatin. The crushing strength and disintegration times of the tablets increased with higher binder concentration, while their friability decreased. Although gelatin produced four tablets with higher crushing strength, okra gum produced tablets with longer disintegration times than those containing gelatin. It was finally concluded from the results that okra gum may be a useful hydrophilic matrixing agent in sustained drug delivery system. Various strategies were developed in order to overcome these issues, offering the opportunity to tailor the physical and chemical properties of okra gum thus yielding materials that may find a wide range of applications. Extraction and purification of okra gum was carried out from okra pods. Followed by carboxymethylated and phosphorylation of extracted okra gum, which was carried out along with optimization of reaction parameter of the primary derivatives that is carboxymethylated okra gum and hydroxyl propyl okra phosphate, followed by drug carriers preparation. By the second modification carboxymethylated okra gum and hydroxyl propyl okra phosphate were carried out by cross linking acrylic acid, N, N-methylene acryl amide, hydroxyethyl methacrylate (HEMA) respectively synthesized cross-linked polymer were further investigated as drug carriers by formulating as tablet for sustained drug release. The drug release of different formulations were measured in relation to time and also compared with the standard drugs. Further mathematical modeling was implemented to know the order of release behavior of formulated tables.

• Author : Vladimir Torchilin
• Publisher : Springer Science & Business Media
• Release Date : 2008-03-21
• Total pages : 474
• ISBN : 9780387765549
• File Size : 25,8 Mb
• Total Download : 880
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Download Multifunctional Pharmaceutical Nanocarriers in PDF, Epub, and Kindle

The editors have brought together leading experts in multifunctional nanopharmaceuticals to provide cutting edge information; a critical overview of the field; and analysis of current and potential future developments to speed the subject’s rapid development.

• Author : Ecaterina Andronescu,Alexandru Mihai Grumezescu
• Publisher : Elsevier
• Release Date : 2017-04-11
• Total pages : 1034
• ISBN : 9780323477215
• File Size : 14,5 Mb
• Total Download : 878
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Download Nanostructures for Oral Medicine in PDF, Epub, and Kindle

Nanostructures for Oral Medicine presents an up-to-date examination of the applications and effects of nanostructured materials in oral medicine, with each chapter addressing recent developments, specific applications, and uses of nanostructures in the oral administration of therapeutic agents in dentistry. The book also includes coverage of the biocompatibility of nanobiomaterials and their remarkable potential in improving human health and in reducing environmental pollution. Emerging advances, such as Dr. Franklin Tay's concept of a new nanotechnology process of growing extremely small, mineral-rich crystals and guiding them into the demineralized gaps between collagen fibers to prevent the aging and degradation of resin-dentin bonding is also discussed. This work will be of great value to those who work in oral medicine, providing them with a resource to gain a greater understanding of how nanotechnology can help them create more efficient, cost-effective products. In addition, it will be of great interest to those who work in materials science who wish to gain a greater appreciation of how nanostructured materials are applied in this field. Outlines the major uses of nanostructured materials for oral medicine, including the properties of each material discussed and how it should best be applied Explores how nanostructured materials enable the creation of more effective drug delivery systems in oral medicine Discusses how novel uses of nanostructured materials may be applied in oral medicine to create more effective devices

• Author : Amit Kumar Nayak,Md Saquib Hasnain,Dilipkumar Pal
• Publisher : Springer Nature
• Release Date : 2021-07-05
• Total pages : 185
• ISBN : 9789811622717
• File Size : 33,6 Mb
• Total Download : 310
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Download Ionically Gelled Biopolysaccharide Based Systems in Drug Delivery in PDF, Epub, and Kindle

This volume provides a thorough insight into the chemistry and mechanism of ionic gelations of various ionic biopolysaccharides, like alginate, gellan gum, pectin, chitosan, carboxymethyl cellulose, etc., and the applications of various ionically gelled biopolysaccharides in drug delivery fields, with chapters emphasizing the recent advances in the field by the experts. This book will be of interest to graduate students and academic and industry researchers from pharmacy, biotechnology, bioengineering, biomedical and material sciences fields.

• Author : Amit Kumar Nayak,Md Saquib Hasnain
• Publisher : Springer Nature
• Release Date : 2020-07-11
• Total pages : 386
• ISBN : 9783030469238
• File Size : 47,6 Mb
• Total Download : 834
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Download Advanced Biopolymeric Systems for Drug Delivery in PDF, Epub, and Kindle

This book discusses the recent innovations in the development of various advanced biopolymeric systems, including gels, in situ gels, hydrogels, interpenetrating polymer networks (IPNs), polyelectrolyte complexes (PECs), graft co-polymers, stimuli-responsive polymers, polymeric nanoparticles, nanocomposites, polymeric micelles, dendrimers, liposomes and scaffolds. It also examines their applications in drug delivery.

• Author : Felix Kratz,Peter Senter,Henning Steinhagen
• Publisher : John Wiley & Sons
• Release Date : 2013-09-30
• Total pages : 1828
• ISBN : 9783527647750
• File Size : 55,5 Mb
• Total Download : 110
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Download Drug Delivery in Oncology in PDF, Epub, and Kindle

In this first authoritative overview on modern cancer chemotherapy 121 international specialists have contributed their experience and recent data for what is likely to become the gold standard in the field. The authors summarize knowledge gained over the past decade, from basic concepts to successful applications in the clinic, covering active and passive targeting strategies as well as tissue-specific approaches. All current and future targeted delivery systems are discussed, from ligand-based to antibody-based polymer-based systems, right up to micro- and nanoparticulate systems. A special section covers the delivery of nucleic acid therapeutics, such as siRNA, miRNA and antisense nucleotides. In each case, a description of the basic technique is followed by a discussion of the latest preclinical and clinical developments in the field. By virtue of its clear and didactic structure, rich illustrative material and summary chapters, this handbook and ready reference enables the efficient transfer of knowledge between different disciplines, from basic research to the clinician and vice versa. It is equally well suited for professionals, researchers and students in medical oncology and cancer biology, and is also excellent for teaching medical students the foundations of 21st century cancer chemotherapy.

• Author : Amit Kumar Nayak,Md Saquib Hasnain,Tejraj M. Aminabhavi
• Publisher : Academic Press
• Release Date : 2021-02-15
• Total pages : 358
• ISBN : 9780128213568
• File Size : 10,6 Mb
• Total Download : 581
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Download Tailor-Made Polysaccharides in Biomedical Applications in PDF, Epub, and Kindle

Tailor-Made Polysaccharides in Biomedical Applications provides extensive details on all the vital precepts, basics, and fundamental aspects of tailored polysaccharides in the pharmaceutical and biotechnological industries. This information provides readers with the foundation for understanding and developing high-quality products. The utilization of natural polymeric excipients in numerous healthcare applications demands the replacement of the synthetic polymers with natural polymers. Natural polymers are superior in terms of biocompatibility, biodegradability, economic extraction, and ready availability. Natural polymers are especially useful in that they are a renewable source of raw materials, as long as they are grown sustainably. Among these natural polymers, polysaccharides are considered as excellent excipients because they are nontoxic, stable, and biodegradable. Several research innovations have been carried out using polysaccharides in drug delivery applications. This book offers a comprehensive resource to understand the potential of these materials in forming new drug delivery methods. It will be useful to biomedical researchers, chemical engineers, regulatory scientists, and students who are actively involved in developing pharmaceutical products for biomedical applications by using tailor-made polysaccharides. Provides methodology for the design, development, and selection of tailor-made polysaccharides in biomedical applications, including for particular therapeutic applications Includes illustrations demonstrating the mechanism of biological interaction of tailor-made polysaccharides Discusses the regulatory aspects and demonstrates the clinical efficacy of tailor-made polysaccharides

• Author : Desiree Nedra Karunaratne
• Publisher : BoD – Books on Demand
• Release Date : 2012-10-31
• Total pages : 652
• ISBN : 9789535108191
• File Size : 37,5 Mb
• Total Download : 692
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Download The Complex World of Polysaccharides in PDF, Epub, and Kindle

The complex world of polysaccharides is a compilation of the characteristics of a variety of polysaccharides from plants, animals and microorganisms. The diversity of these polysaccharides arises from the structural variations and the monosaccharide content which is under genetic control. The chemical and physical properties have made them useful in many pharmaceutical, food and industrial applications. These properties of the polysaccharides determine their biological activity and their function in various applications. The role played by polysaccharides in preservation and protection of food, as carriers of nutrients and drugs, their ability to interact with molecules both for efficient delivery as well as improving textures of food colloids and their use as therapeutics are some of the functions discussed.