Personalized Psychiatry
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Personalized Psychiatry
- Author : Bernhard Baune
- Publisher : Academic Press
- Release Date : 2019-10-16
- Total pages : 604
- ISBN : 9780128131770
- File Size : 39,8 Mb
- Total Download : 398
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Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders. Combines neurobiology with basic science methodologies in genomics, epigenomics and transcriptomics Demonstrates how the statistical modeling of interacting biological and clinical information could transform the future of psychiatry Addresses fundamental questions and requirements for personalized psychiatry from a basic research and translational perspective
Personalized Psychiatry
- Author : Ives Cavalcante Passos,Benson Mwangi,Flávio Kapczinski
- Publisher : Springer
- Release Date : 2019-02-12
- Total pages : 180
- ISBN : 9783030035532
- File Size : 16,8 Mb
- Total Download : 407
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This book integrates the concepts of big data analytics into mental health practice and research. Mental disorders represent a public health challenge of staggering proportions. According to the most recent Global Burden of Disease study, psychiatric disorders constitute the leading cause of years lost to disability. The high morbidity and mortality related to these conditions are proportional to the potential for overall health gains if mental disorders can be more effectively diagnosed and treated. In order to fill these gaps, analysis in science, industry, and government seeks to use big data for a variety of problems, including clinical outcomes and diagnosis in psychiatry. Multiple mental healthcare providers and research laboratories are increasingly using large data sets to fulfill their mission. Briefly, big data is characterized by high volume, high velocity, variety and veracity of information, and to be useful it must be analyzed, interpreted, and acted upon. As such, focus has to shift to new analytical tools from the field of machine learning that will be critical for anyone practicing medicine, psychiatry and behavioral sciences in the 21st century. Big data analytics is gaining traction in psychiatric research, being used to provide predictive models for both clinical practice and public health systems. As compared with traditional statistical methods that provide primarily average group-level results, big data analytics allows predictions and stratification of clinical outcomes at an individual subject level. Personalized Psychiatry – Big Data Analytics in Mental Health provides a unique opportunity to showcase innovative solutions tackling complex problems in mental health using big data and machine learning. It represents an interesting platform to work with key opinion leaders to document current achievements, introduce new concepts as well as project the future role of big data and machine learning in mental health.
Advancing Healthcare Through Personalized Medicine
- Author : Priya Hays
- Publisher : Springer Nature
- Release Date : 2021-09-27
- Total pages : 755
- ISBN : 9783030801007
- File Size : 36,7 Mb
- Total Download : 700
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This book provides a unique perspective on the biomedical and societal implications of personalized medicine and how it helps to mitigate the healthcare crisis and rein in ever-growing expenditure. It introduces the reader to the underlying concepts at the heart of personalized medicine. An innovative second edition, this book functions as an update to the successful first edition to include new, state-of-the-art information and advancements in the fast-paced field of personalized medicine. Chapters examine pharmacogenomics, targeted therapies, individualized diagnosis and treatment, and cancer immunotherapies. The book also features an essential discussion on how the advent of genomic technologies gives clinicians the capability to predict and diagnose disease more efficiently and offers a detailed up-to-date compilation of clinical trials in cancer leading to breakthrough therapies. The book also addresses the impact of Big Data on personalized medicine and the newfound applications of digital health and artificial intelligence. A work that advocates for a patient-centered approach, Advancing Healthcare Through Personalized Medicine, Second Edition is an invaluable text for clinicians, healthcare providers, and patients.
Extraordinary Science and Psychiatry
- Author : Jeffrey Poland,Serife Tekin
- Publisher : MIT Press
- Release Date : 2017-01-13
- Total pages : 339
- ISBN : 9780262035484
- File Size : 28,8 Mb
- Total Download : 462
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Leading scholars offer perspectives from the philosophy of science on the crisis in psychiatric research that exploded after the publication of DSM-5. Psychiatry and mental health research is in crisis, with tensions between psychiatry's clinical and research aims and controversies over diagnosis, treatment, and scientific constructs for studying mental disorders. At the center of these controversies is the Diagnostic and Statistical Manual of Mental Disorders (DSM), which—especially after the publication of DSM-5—many have found seriously flawed as a guide for research. This book addresses the crisis and the associated “extraordinary science” (Thomas Kuhn's term for scientific research during a state of crisis) from the perspective of philosophy of science. The goal is to help reconcile the competing claims of science and phenomenology within psychiatry and to offer new insights for the philosophy of science. The contributors discuss the epistemological origins of the current crisis, the nature of evidence in psychiatric research, and the National Institute for Mental Health's Research Domain Criteria project. They consider particular research practices in psychiatry—computational, personalized, mechanistic, and user-led—and the specific categories of schizophrenia, depressive disorder, and bipolar disorder. Finally, they examine the DSM's dubious practice of pathologizing normality. Contributors Richard P. Bentall, John Bickle, Robyn Bluhm, Rachel Cooper, Kelso Cratsley, Owen Flanagan, Michael Frank, George Graham, Ginger A. Hoffman, Harold Kincaid, Aaron Kostko, Edouard Machery, Jeffrey Poland, Claire Pouncey, Şerife Tekin, Peter Zachar
Pharmacogenomics in Psychiatry
- Author : Matthias Schwab,Wolfgang P. Kaschka,Edoardo Spina
- Publisher : Karger Medical and Scientific Publishers
- Release Date : 2010-01-01
- Total pages : 148
- ISBN : 9783805594981
- File Size : 42,7 Mb
- Total Download : 727
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In recent years, there have been major developments in the fields of pharmacogenetics and pharmacogenomics, with the potential to make drug treatments in psychiatric medicine more effective. However, improvements in drug efficacy and tolerability, as well as finding the optimal dosage, can only be realized if in vivo mechanisms of drug action and ADME (absorption, distribution, metabolism, excretion) processes (pharmacokinetics) of psychopharmacological agents are better understood. In this volume, current progress and perspectives in pharmacogenetic testing of drug-metabolizing enzymes, drug transporters and other drug targets involved in the response to psychotropic agents are described extensively. This provides a timely overview of what has been achieved in the area of psychiatric pharmacogenomics alongside some promising directions and perspectives for future research. Psychiatrists, general medical doctors as well as pharmacologists and clinical pharmacologists will find new insights into the development and applications of pharmacogenomics in psychiatry.
Advances in Psychiatry
- Author : Afzal Javed,Kostas N. Fountoulakis
- Publisher : Springer
- Release Date : 2018-07-06
- Total pages : 740
- ISBN : 9783319705545
- File Size : 20,8 Mb
- Total Download : 790
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This book is the newest edition on the series ‘advances in psychiatry’. The previous 3 volumes can be found online at http://www.wpanet.org/detail.php?section_id=10&content_id=660 . They were highly successful in covering a broad area of psychiatry from different perspectives and angles and by reflecting both specialized but also international and global approaches. This series have guaranteed quality therefore can be used by different scientific groups for teaching and learning and also as a means for fast dissemination of advanced research and transformation of research findings into the everyday clinical practice.
Precision Psychiatry
- Author : Leanne M. Williams, Ph.D.,Laura M. Hack, M.D., Ph.D.
- Publisher : American Psychiatric Pub
- Release Date : 2021-10-15
- Total pages : 302
- ISBN : 9781615371587
- File Size : 51,6 Mb
- Total Download : 289
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Precision psychiatry, as outlined in this groundbreaking book, presents a new path forward. By integrating findings from basic and clinical neuroscience, clinical practice, and population-level data, the field seeks to develop therapeutic approaches tailored for specific individuals with a specific constellation of health issues, characteristics, strengths, and symptoms.
Convergence Mental Health
- Author : Harris A. Eyre,Michael Berk,Helen Lavretsky,III Charles Reynolds
- Publisher : Oxford University Press
- Release Date : 2021-01-05
- Total pages : 448
- ISBN : 9780197506295
- File Size : 18,5 Mb
- Total Download : 139
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Modern mental health issues are characterized by their complex, multi-systemic nature and broad societal impact, making them poorly suited to siloed approaches of thinking and innovation. Convergence science integrates knowledge, tools, and thought strategies from various fields and is the focal point where novel insights arise. Convergence Mental Health presents a blueprint for leveraging convergence science within the context of mental health in order to improve patient outcomes and health care systems.
Handbook on Optimizing Patient Care in Psychiatry
- Author : Amresh Shrivastava,Avinash De Sousa,Nilesh Shah
- Publisher : Taylor & Francis
- Release Date : 2022-11-15
- Total pages : 843
- ISBN : 9780429638572
- File Size : 38,5 Mb
- Total Download : 144
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This handbook examines current mental health research, challenges in patient care, and advances in clinical psychiatry with the aim of improving approaches toward the screening of at-risk individuals, facilitating access to care, and supervising rehabilitation. Combining evidence-based research with clinical case studies, international experts provide detailed, holistic insights into our understanding of mental disorders through biological, social, interpersonal, and economical lenses. Models of intervention, prevention, and treatment are provided, along with methods for continued care and patient advocacy. Finally, experts analyze the future of psychiatric research and mental health care. Readers will gain greater understanding of the finer nuances of handling psychiatric cases and a holistic perspective of optimizing patient care within this field. This innovative book contributes to the development of community management of various psychiatric disorders and will be of interest to case managers, mental health workers, doctors, nurses, and many more.
Psychiatric Genomics
- Author : Evangelia Eirini Tsermpini,Martin Alda,George P. Patrinos
- Publisher : Academic Press
- Release Date : 2022-03-18
- Total pages : 418
- ISBN : 9780128214008
- File Size : 39,5 Mb
- Total Download : 211
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Psychiatric Genomics presents and synthesizes available knowledge in the field of psychiatric genomics, offering methodologies to advance new research and aid clinical translation. After providing an introduction to genomics and psychiatry, international experts discuss the genomic basis of schizophrenia, bipolar disorder, depression, personality disorders, anxiety disorders, addictions, eating disorders, and sleep disorders, among other disorders. In addition, recommendations for next steps in clinical implementation and drug discovery are discussed in-depth, with chapters dedicated to pharmacogenomics and antipsychotics, antidepressants and mood stabilizers, adverse drug reactions, implementation of pharmacogenomics in psychiatric clinics, and ethical issues. Finally, methods sections provide a solid grounding in research approaches and computational analytics, from using animal models in psychiatric genomics and accessing biobanks, to employing computational analysis, genome-wide association studies (GWAS), brain pathophysiology, and endophenotypes in psychiatric research. Thoroughly examines the genetic mechanisms underlying a broad range of psychiatric disorders Offers genomic methodologies and analytical approaches supporting new research and clinical translation, including personalized diagnosis and treatment models Features chapter contributions from international leaders in the field
The American Psychiatric Association Publishing Textbook of Personality Disorders
- Author : Andrew E. Skodol,John M. Oldham
- Publisher : American Psychiatric Pub
- Release Date : 2021-03-31
- Total pages : 760
- ISBN : 9781615373741
- File Size : 50,5 Mb
- Total Download : 608
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The subject of personality -- what makes each of us unique and different from one another -- has long been a topic of universal fascination. From a medical perspective, research on personality disorders has expanded with the advent of standardized diagnostic systems. This continuing and increased activity and progress in the field spurred the development of this third edition of The American Psychiatric Association Publishing Textbook of Personality Disorders. With an emphasis on updating the information most relevant to clinicians, this new edition features contributions from established experts in the field as well as a new generation of scientists. Dozens of tables, illustrative figures, and real-life case examples summarize the vast data that continue to accumulate in five key areas: Clinical concepts, including theories of personality disorders, as well as their manifestations, assessment, and diagnosis. This opening section also describes the Alternative DSM-5 Model for Personality Disorders in detail. Risk factors for, and the etiology and impact of, personality disorders. This section of the book examines data on prevalence, sociodemographics, and levels of functional impairment associated with personality disorders. It offers both a developmental and a genetic/neurobiological perspective and describes the symptomatic and functional outcomes of personality disorders. Treatment options across therapeutic modalities. A new, cutting-edge chapter argues for the early identification of borderline psychopathology in children and young adolescents, in an effort to prevent full-blown disorder later in life. Additional chapters delve into an array of individual psychotherapies, pharmacotherapeutic options, and group, family, and couples therapies. Guidance on forming and maintaining a therapeutic alliance and on avoiding boundary violations in treating patients with personality disorders is provided. Special problems, populations, and settings, including suicide, substance use disorders, antisocial behavior, personality pathology in general medical settings, and personality disorders among active-duty military. The usefulness of translational research to deepen understanding of the biopsychosocial nature of the personality disorders, particularly borderline personality disorder. This comprehensive textbook is an essential resource for clinicians looking to stay on the vanguard of a rapidly growing field.
Precision Medicine in Clinical Practice
- Author : Mandana Hasanzad
- Publisher : Springer Nature
- Release Date : 2022-09-30
- Total pages : 259
- ISBN : 9789811950827
- File Size : 47,5 Mb
- Total Download : 852
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The book provides complete information on the cornerstones of precision medicine through the omics approach. Clinical applications of genomics and precision medicine have progressed from a theoretical wish list to an impactful force in medical practice.Step-by-step descriptions are provided from basics to the future application and its benefit in clinical practice. Precision medicine aims to personalize health care by tailoring decisions and treatments to each individual in every possible way. Precision medicine includes pharmacogenomics. Essential information is provided on the role of precision medicine and pharmacogenomics in the clinical practice of cancer, cardiovascular disease, diabetes, psychiatric disease, and also the importance for healthcare professionals. This book will assist the practitioners how to integrate precision medicine and pharmacogenomics data into their clinical practice. It is hoped that physicians, pharmacists, and scientists with basic scientific knowledge of precision medicine will findthis book useful.
Functional Neuromarkers for Psychiatry
- Author : Juri D. Kropotov
- Publisher : Academic Press
- Release Date : 2016-05-03
- Total pages : 498
- ISBN : 9780124105201
- File Size : 42,9 Mb
- Total Download : 905
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Functional Neuromarkers for Psychiatry explores recent advances in neuroscience that have allowed scientists to discover functional neuromarkers of psychiatric disorders. These neuromarkers include brain activation patterns seen via fMRI, PET, qEEG, and ERPs. The book examines these neuromarkers in detail—what to look for, how to use them in clinical practice, and the promise they provide toward early detection, prevention, and personalized treatment of mental disorders. The neuromarkers identified in this book have a diagnostic sensitivity and specificity higher than 80%. They are reliable, reproducible, inexpensive to measure, noninvasive, and have been confirmed by at least two independent studies. The book focuses primarily on the analysis of EEG and ERPs. It elucidates the neuronal mechanisms that generate EEG spontaneous rhythms and explores the functional meaning of ERP components in cognitive tasks. The functional neuromarkers for ADHD, schizophrenia, and obsessive-compulsive disorder are reviewed in detail. The book highlights how to use these functional neuromarkers for diagnosis, personalized neurotherapy, and monitoring treatment results. Identifies specific brain activation patterns that are neuromarkers for psychiatric disorders Includes neuromarkers as seen via fMRI, PET, qEEG, and ERPs Addresses neuromarkers for ADHD, schizophrenia, and OCD in detail Provides information on using neuromarkers for diagnosis and/or personalized treatment
Big Data in Psychiatry and Neurology
- Author : Ahmed A. Moustafa
- Publisher : Academic Press
- Release Date : 2021-06-24
- Total pages : 384
- ISBN : 9780128230022
- File Size : 54,6 Mb
- Total Download : 844
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Big Data in Psychiatry and Neurology provides an up-to-date overview of achievements in the field of big data in Psychiatry and Medicine, including applications of big data methods to aging disorders (e.g., Alzheimer’s disease and Parkinson’s disease), mood disorders (e.g., major depressive disorder), and drug addiction. This book will help researchers, students and clinicians implement new methods for collecting big datasets from various patient populations. Further, it will demonstrate how to use several algorithms and machine learning methods to analyze big datasets, thus providing individualized treatment for psychiatric and neurological patients. As big data analytics is gaining traction in psychiatric research, it is an essential component in providing predictive models for both clinical practice and public health systems. As compared with traditional statistical methods that provide primarily average group-level results, big data analytics allows predictions and stratification of clinical outcomes at an individual subject level. Discusses longitudinal big data and risk factors surrounding the development of psychiatric disorders Analyzes methods in using big data to treat psychiatric and neurological disorders Describes the role machine learning can play in the analysis of big data Demonstrates the various methods of gathering big data in medicine Reviews how to apply big data to genetics
New Directions in Psychiatry
- Author : Maurizio Pompili,Roger McIntyre,Andrea Fiorillo,Norman Sartorius
- Publisher : Springer Nature
- Release Date : 2020-06-08
- Total pages : 230
- ISBN : 9783030426378
- File Size : 33,6 Mb
- Total Download : 215
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This book focuses on hot issues faced by clinicians in everyday clinical practice, and provides in-depth analyses of both met and unmet needs in the management of psychiatric disorders. It has been repeatedly shown that the needs of patients, relatives, the community at large and those of the governmental bodies only partially overlap. For instance, patients in their families are more concerned about quality of life, treatment, autonomy, and independent living; whereas governmental stakeholders are typically more concerned about relapse prevention and reduction of hospitalizations. As such, a volume bridging the gap between theoretical notions and practical understanding of patients’ untreated aspects of their psychiatric disorders is much needed. Instead of focusing on traditional descriptions of psychopathology and diagnostic criteria, the volume guides readers to core problems for each topic, taking into account new approaches in the classification of mental disorders as proposed by DSM-5. It elaborates on much-debated controversial problems such as the assessment and treatment of psychomotor agitation, and non-adherence to treatment that impacts on the psychiatric context. With its unique approach, this volume appeals to anyone with an interest in the field, including researchers, clinicians, and trainees.
Can Artificial Intelligence and Big Data Analytics Save the Future of Psychiatry?
- Author : A. George Awad
- Publisher : iUniverse
- Release Date : 2023-04-26
- Total pages : 193
- ISBN : 9781663252685
- File Size : 15,9 Mb
- Total Download : 593
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This book is the second of the series about the imperatives for the search for new psychiatry. As stated in my recent 2021 book about: The Search for New Psychiatry, current psychiatric practices have failed many: patients and their families, their doctors and the society at large. That was the end of the 2021 book and the beginning of this book as a follow up in search for pathways to a new and more effective science-based practice Based on its major contributions to the recent successful and expedient development of the Covid 19 vaccines, I am proposing the same pathway of using the new revolution in informatics as the way to save and secure the future of psychiatry and that is what I am recommending in this book reaping the benefit of AI and Big Data Analytics but with a wide open eye on its limits, reliability, risks, unforeseen or unintentional harms. Part Two of the book deals with a number of perineal and also new challenges that continue to require better understanding and resolution. Among the phenomenological and nosological challenges, the recent development by Neurology of its subspeciality of Behavioral Neurology in competition to Neuropsychiatry, is reviewed in terms of an opportunity for integration of the tow subspecialities towards the creation of a new third field of “Clinical Neurosciences”. Other challenges included are: The Subjective /Objective Dichotomy, Lunacy and the Moon- reflections on the interactions of the brain and environment and Woke Psychiatry, what is it? Several other clinical challenges include: The Past is Coming Back as The Future -The Rise, Fall and Rise Again of Psychedelics, Loneliness as the silent disorder and several other challenges. At the end, a postscript has been hastily added in memory of a close friend, a pioneering psychopharmacologist but above all an empathic humanist, Professor Thomas Arthur Ban or as he always preferred, Tom.
Fads and Fallacies in Psychiatry
- Author : Joel Paris
- Publisher : Cambridge University Press
- Release Date : 2023-03-31
- Total pages : 153
- ISBN : 9781009245753
- File Size : 20,7 Mb
- Total Download : 201
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This text examines the fads and fallacies, both past and present, that have plagued psychiatric diagnosis, treatments and research. It argues that such practices have led to an over-diagnosis of conditions such as depression, bipolar disorder, ADHD, PTSD and autism. It examines the over-treatment of psychiatric disorders with pharmaceuticals, and asks if neuroscience will actually hold the answers to the biggest questions in the field. Thoroughly updated in light of new research, this new edition addresses some of the more recent developments in psychiatry, including behavioural genetics, genome-wide association studies, and brain imaging. It looks at new advances in psychotherapies and argues for a broad biopsychosocial model. The book will inform psychiatrists, clinical psychologists, other mental health professionals, and medical students of the limits of mental health practice and the importance of adopting cautious conservatism and the principles of evidence-based practice.
How to Succeed in Psychiatry
- Author : Andrea Fiorillo,Iris Calliess,Henning Sass
- Publisher : John Wiley & Sons
- Release Date : 2012-01-30
- Total pages : 352
- ISBN : 9781119961949
- File Size : 19,7 Mb
- Total Download : 400
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Aimed at recently qualified psychiatrists or those looking to qualify soon, How to Succeed in Psychiatry is not a source of clinical information but a survival guide to help you through the first years practising psychiatry. This book covers the topics you won’t find in standard textbooks. It deals with daily problems and practical solutions for young psychiatrists. Psychiatric training is less team based than other specialties, so there is less opportunity for learning from colleagues than one would expect: this book helps to fill that gap. The book opens with an overview of psychiatry training, describing the similarities and differences among various countries. Subsequent chapters address the opportunities for research and how to publish the results. Psychotherapy and community psychiatry each merit their own chapter on training. Next, the book guides you through the transition phase into a job, discussing opportunities in both the public and private sectors and considering how to choose the best career for you. It reviews important general considerations, such as ethics, professionalism, leadership and management, how to avoid stress and burn out, and how to liaise with other specialties. The book closes with an account of the role of psychiatry associations and continuing professional development. Written by early career psychiatrists from around the world, this book provides invaluable first-hand experience to all those wishing to embark on a career in this exciting discipline. Practical tips for young psychiatrists starting their careers on the wards or in private practice Advice on the transition phase at the end of training, career choice and job opportunities
Cognition in Mood Disorders
- Author : Allan H. Young,Catherine Harmer
- Publisher : Frontiers Media SA
- Release Date : 2020-04-17
- Total pages : 178
- ISBN : 9782889636662
- File Size : 12,7 Mb
- Total Download : 374
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International Society for Affective Disorders (ISAD) exists to promote research into the mood (affective) disorders through all relevant scientific disciplines, including genetics, neuroscience and the social and behavioural sciences. Inter-disciplinary research approaches are particularly highly valued by the society. www.isad.org.uk
Social Interaction in Neuropsychiatry
- Author : Leonhard Schilbach,Danilo Bzdok,Victoria Leong,Elizabeth Redcay,Frieder Michel Paulus,Kevin A. Pelphrey
- Publisher : Frontiers Media SA
- Release Date : 2021-06-30
- Total pages : 223
- ISBN : 9782889669295
- File Size : 40,6 Mb
- Total Download : 914
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PDF book entitled Social Interaction in Neuropsychiatry written by Leonhard Schilbach,Danilo Bzdok,Victoria Leong,Elizabeth Redcay,Frieder Michel Paulus,Kevin A. Pelphrey and published by Frontiers Media SA which was released on 2021-06-30 with total hardcover pages 223, the book become popular and critical acclaim.
Psychiatric Neuroethics
- Author : Walter Glannon
- Publisher : Oxford University Press, USA
- Release Date : 2019-01-10
- Total pages : 409
- ISBN : 9780198758853
- File Size : 27,5 Mb
- Total Download : 717
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Advances in psychiatric research and clinical psychiatry in the last 30 years have given rise to a host of new questions that lie at the intersection of psychiatry, neuroscience, philosophy and law. Such questions include: -Are psychiatric disorders diseases of the brain, caused by dysfunctional neural circuits and neurotransmitters? -What role do genes, neuro-endocrine, neuro-immune interactions and the environment play in the development of these disorders? -How do different explanations of the etiology and pathophysiology of mental illness influence diagnosis, prognosis and decisions about treatment? -Would it be rational for a person with a chronic treatment-resistant disorder to request euthanasia or assisted suicide to end their suffering? -Could psychiatric disorders be predicted and prevented? Psychiatric Neuroethics explores these questions in a comprehensive and systematic way, discussing the medical and philosophical implications of neuroscience and the Research Domain Criteria (RDoc) in the fields of psychiatry and mental health. It examines the extent to which circuit-based criteria can offer a satisfactory explanation of psychiatric disorders and how they compare with the symptom-based criteria of the Diagnostic and Statistical Manual of Mental Disorders (DSMV). This book will be of interest to a multidisciplinary audience, including psychiatrists, neurologists, neurosurgeons, philosophers, psychologists and legal theorists.