Neuroscience Of Alcohol

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Neuroscience of Alcohol

Neuroscience of Alcohol
  • Author : Victor R. Preedy
  • Publisher : Academic Press
  • Release Date : 2019-03-19
  • Total pages : 736
  • ISBN : 9780128131268
  • File Size : 40,6 Mb
  • Total Download : 542

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Neuroscience of Alcohol: Mechanisms and Treatment presents the fundamental information necessary for a thorough understanding of the neurobiological underpinnings of alcohol addiction and its effects on the brain. Offering thorough coverage of all aspects of alcohol research, treatment and prevention, and containing contributions from internationally recognized experts, the book provides students, early-career researchers, and investigators at all levels with a fundamental introduction to all aspects of alcohol misuse. Alcohol is one of the world’s most common addictive substances, with about two billion individuals worldwide consuming it in one form or another and three million annual deaths that are associated with alcohol misuse. Alcohol alters a variety of neurological processes, from molecular biology, to cognition. Moreover, addiction to alcohol can lead to numerous other health concerns and damage virtually every organ system in the body, making diagnosis and treatment of individuals addicted to alcohol of critical importance. Integrates cutting-edge research on the pharmacological, cellular and molecular aspects of alcohol use, along with its effects on neurobiological function Discusses alcohol use as a component of dual-use and poly addictions Outlines numerous screening and treatment strategies for alcohol misuse Covers both the physical and psychological effects of alcohol use and withdrawals to provide a fully-formed view of alcohol dependency and its effects

Neurobiology of Alcohol and the Brain

Neurobiology of Alcohol and the Brain
  • Author : Ashok K. Singh
  • Publisher : Academic Press
  • Release Date : 2020-10-01
  • Total pages : 364
  • ISBN : 9780128198919
  • File Size : 37,9 Mb
  • Total Download : 516

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Neurobiology of Alcohol and the Brain addresses addiction related problems, reviewing both mechanisms and withdrawal systems surrounding alcohol addiction. Chapters discuss mechanisms of rewarding, aversive effects, alcohol’s interaction with other drugs (and ensuing adverse consequences), and current and novel treatments. Lastly, the reader is provided with examples of an experimental study that describes the possible protective effects of gold nanoparticles against alcohol addiction in rats subjected to alcohol self-administration. Provides an exhaustive overview of neurobiology of alcohol addiction, including significant recent advances Discusses the mechanisms underlying the adverse effects of alcohol-drug mixtures Includes recent experimental studies on gold nanoparticles

Never Enough

Never Enough
  • Author : Judith Grisel
  • Publisher : Anchor
  • Release Date : 2020-01-14
  • Total pages : 258
  • ISBN : 9780525434900
  • File Size : 39,5 Mb
  • Total Download : 831

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A NEW YORK TIMES BESTSELLER From a renowned behavioral neuroscientist and recovering addict, a rare page-turning work of science that draws on personal insights to reveal how drugs work, the dangerous hold they can take on the brain, and the surprising way to combat today's epidemic of addiction. Judith Grisel was a daily drug user and college dropout when she began to consider that her addiction might have a cure, one that she herself could perhaps discover by studying the brain. Now, after twenty-five years as a neuroscientist, she shares what she and other scientists have learned about addiction, enriched by captivating glimpses of her personal journey. In Never Enough, Grisel reveals the unfortunate bottom line of all regular drug use: there is no such thing as a free lunch. All drugs act on the brain in a way that diminishes their enjoyable effects and creates unpleasant ones with repeated use. Yet they have their appeal, and Grisel draws on anecdotes both comic and tragic from her own days of using as she limns the science behind the love of various drugs, from marijuana to alcohol, opiates to psychedelics, speed to spice. With more than one in five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide, and Grisel delves with compassion into the science of this scourge. She points to what is different about the brains of addicts even before they first pick up a drink or drug, highlights the changes that take place in the brain and behavior as a result of chronic using, and shares the surprising hidden gifts of personality that addiction can expose. She describes what drove her to addiction, what helped her recover, and her belief that a “cure” for addiction will not be found in our individual brains but in the way we interact with our communities. Set apart by its color, candor, and bell-clear writing, Never Enough is a revelatory look at the roles drugs play in all of our lives and offers crucial new insight into how we can solve the epidemic of abuse.

Alcohol and the Nervous System

Alcohol and the Nervous System
  • Author : Edith V. Sullivan,Adolf Pfefferbaum
  • Publisher : Elsevier
  • Release Date : 2014-10-08
  • Total pages : 704
  • ISBN : 9780444626226
  • File Size : 55,7 Mb
  • Total Download : 717

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Alcohol is the most widely used drug in the world, yet alcoholism remains a serious addiction affecting nearly 20 million Americans. Our current understanding of alcohol's effect on brain structure and related functional damage is being revolutionized by genetic research, basic neuroscience, brain imaging science, and systematic study of cognitive, sensory, and motor abilities. Volume 125 of the Handbook of Clinical Neurology is a comprehensive, in-depth treatise of studies on alcohol and the brain covering the basic understanding of alcohol's effect on the central nervous system, the diagnosis and treatment of alcoholism, and prospect for recovery. The chapters within will be of interest to clinical neurologists, neuropsychologists, and researchers in all facets and levels of the neuroscience of alcohol and alcoholism. The first focused reference specifically on alcohol and the brain Details our current understanding of how alcohol impacts the central nervous system Covers clinical and social impact of alcohol abuse disorders and the biomedical consequences of alcohol abuse Includes section on neuroimaging of neurochemical markers and brain function

Neurobiology of Alcohol Dependence

Neurobiology of Alcohol Dependence
  • Author : Antonio Noronha,Changhai Cui,Robert Adron Harris,John C. Crabbe
  • Publisher : Elsevier
  • Release Date : 2014-05-02
  • Total pages : 566
  • ISBN : 9780124071551
  • File Size : 37,7 Mb
  • Total Download : 695

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Recent scientific advances have provided substantial information on the brain circuits and pathways relevant to various aspects of dependence. Neurobiology of Alcohol Dependence highlights the most recent data at the molecular, cellular, neurocircuitry, and behavioral levels, fostering an understanding how neuroplasticity and neuroadaptation occur, and how different neural pathways and neurocircuits contribute to dependence. Highlights recent advances in understanding alcohol addiction from molecular, cellular, neurocircuitry, and behavioral levels Integrates several emerging areas of research and discusses the application of novel research techniques to the understanding of alcohol dependence Chapters authored by leaders in the field around the globe — the broadest, most expert coverage available


  • Author : Gene M. Heyman
  • Publisher : Harvard University Press
  • Release Date : 2009-10-15
  • Total pages : 216
  • ISBN : 9780674053991
  • File Size : 54,6 Mb
  • Total Download : 259

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In a book sure to inspire controversy, Gene Heyman argues that conventional wisdom about addiction - that it is a disease, a compulsion beyond conscious control - is wrong. At the heart of Heyman's analysis is a startling view of choice and motivation that applies to all choices, not just the choice to use drugs. Heyman’s analysis of well-established but frequently ignored research leads to unexpected insights into how we make choices - from obesity to McMansionization - all rooted in our deep-seated tendency to consume too much of whatever we like best.

Advances in the Neuroscience of Addiction

Advances in the Neuroscience of Addiction
  • Author : Cynthia M. Kuhn,George F. Koob
  • Publisher : CRC Press
  • Release Date : 2010-04-12
  • Total pages : 242
  • ISBN : 9781420007350
  • File Size : 45,9 Mb
  • Total Download : 222

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Understanding the phenomenon of long-lasting vulnerability to addiction is essential to developing successful treatments. Written by an international team of authorities in their respective fields, Advances in the Neuroscience of Addiction provides an excellent overview of the available and emerging approaches used to investigate the biol

Behavioral Neurobiology of Alcohol Addiction

Behavioral Neurobiology of Alcohol Addiction
  • Author : Wolfgang Sommer,Rainer Spanagel
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-07-28
  • Total pages : 727
  • ISBN : 9783642287206
  • File Size : 32,5 Mb
  • Total Download : 945

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The question how alcohol alters mood states and why this may end up becoming an addiction is puzzling alcohol researchers since decades. In this volume, an assembly of highly distinguished experts and leaders in alcohol addiction research provides lucid presentations of the current knowledge and research challenges as well as interesting viewpoints on future research directions aimed to stimulate communication and convergence between clinical and preclinical researchers, and to renew interest in the vibrant field of alcohol addiction research among a wide scientifically minded audience. Five Current Topics are discussed in this volume: Neurobiological mechanisms of alcoholism, Genetics, Clinical phenotypes and their preclinical models, Brain imaging, and Translational approaches for treatment development, both pharmacological and non-pharmacological. These areas have in our opinion brought alcohol research substantially forward and influenced our thinking about how to reach our common paramount goal, namely to offer effective treatment solutions for an extensive group of patients with largely unmet medical needs.

Alcohol Research & Health

Alcohol Research & Health
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1999
  • Total pages : 344
  • ISBN : UCSC:32106015846345
  • File Size : 48,6 Mb
  • Total Download : 205

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PDF book entitled Alcohol Research & Health written by Anonim and published by Unknown which was released on 1999 with total hardcover pages 344, the book become popular and critical acclaim.

The Genetics of Alcoholism

The Genetics of Alcoholism
  • Author : Henri Begleiter,Benjamin Kissin
  • Publisher : Alcohol and Alcoholism
  • Release Date : 1995
  • Total pages : 420
  • ISBN : 0195088778
  • File Size : 40,5 Mb
  • Total Download : 661

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This volume provides an in-depth look at the genetic influences that contribute to the development of alcoholism. Part I: Epidemiologic Studies contains five chapters that examine the various approaches employed in the study of the genetics of alcoholism. It provides a historical perspectiveand details all the essentials of this subject. Part II: Selective Breeding Studies highlights the results of research involving the selective breeding of rodents. This type of research has produced homogenous strains exhibiting specific behavioral responses considered significant in thedevelopment and maintenance of alcohol dependence. The studies presented in Part III: Phenotypic Studies investigate and analyze phenotypic markers that serve as correlates to the genotypic determinants of alcoholism. Through its broad scope, this volume provides for the first time a panoramic viewof the knowledge available on the hereditary influences of alcoholism.

The Wiley Handbook on the Cognitive Neuroscience of Addiction

The Wiley Handbook on the Cognitive Neuroscience of Addiction
  • Author : Stephen J. Wilson
  • Publisher : John Wiley & Sons
  • Release Date : 2015-07-07
  • Total pages : 552
  • ISBN : 9781118472248
  • File Size : 34,9 Mb
  • Total Download : 927

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This volume provides a thorough and up-to-date synthesis of the expansive and highly influential literature from the last 30 years by bringing together contributions from leading authorities in the field, with emphasis placed on the most commonly investigated drugs of abuse. Emphasises the most commonly investigated drugs of abuse, including alcohol, cocaine, nicotine, and opiates Brings together the work of the leading authorities in all major areas of the field Provides novel coverage of cutting-edge methods for using cognitive neuroscience to advance the treatment of addiction, including real-time neurofeedback and brain stimulation methods Includes new material on emerging themes and future directions in the use of cognitive neuroscience to advance addiction science


  • Author : George F. Koob,Michael A. Arends,Mandy McCracken,Michel Le Moal
  • Publisher : Academic Press
  • Release Date : 2021-07-07
  • Total pages : 402
  • ISBN : 9780128167946
  • File Size : 30,6 Mb
  • Total Download : 103

Download Alcohol in PDF, Epub, and Kindle

A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. ALCOHOL, Volume 3 in the series, explores the molecular, cellular, and neurocircuitry systems in the brain responsible for alcohol addiction using the heuristic three-stage cycle framework of binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation. Outlines the history and behavioral mechanism of action of alcohol relevant to the neurobiology of alcohol addiction Includes neurocircuitry, cellular, and molecular neurobiological mechanisms of alcohol addiction in each stage of the addiction cycle Explores evolving areas of research associated with all three stages of the alcohol addiction cycle, including neurobiological studies of neurodevelopmental effects of early exposure to alcohol, sleep disturbances caused by alcohol, pain interactions with alcohol, sex differences in the response to alcohol, and epigenetic/genetic interactions with alcohol.

The Science of Addiction: From Neurobiology to Treatment

The Science of Addiction: From Neurobiology to Treatment
  • Author : Carlton K. Erickson
  • Publisher : W. W. Norton & Company
  • Release Date : 2007-02-17
  • Total pages : 303
  • ISBN : 9780393704631
  • File Size : 40,8 Mb
  • Total Download : 645

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A leading addictions specialist presents information about the neurobiology of drug and alcohol addictions and how individuals with addictions respond to various therapies. The strong focus on the most commonly addictive drugs--alcohol, nicotine, cocaine, heroin--as well as others, ensures wide coverage of this issue.

Neuroscience of Psychoactive Substance Use and Dependence

Neuroscience of Psychoactive Substance Use and Dependence
  • Author : World Health Organization,WHO
  • Publisher : World Health Organization
  • Release Date : 2004
  • Total pages : 284
  • ISBN : 9789241562355
  • File Size : 46,9 Mb
  • Total Download : 505

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Provides an authoritative summary of current knowledge of the biological basis of substance use behaviours, including their relationship with environmental factors.

Drugs, Addiction, and the Brain

Drugs, Addiction, and the Brain
  • Author : George F. Koob,Michael A. Arends,Michel Le Moal
  • Publisher : Academic Press
  • Release Date : 2014-07-12
  • Total pages : 350
  • ISBN : 9780123869593
  • File Size : 22,7 Mb
  • Total Download : 806

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Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems in the brain that are responsible for drug addiction. Common neurobiological elements are emphasized that provide novel insights into how the brain mediates the acute rewarding effects of drugs of abuse and how it changes during the transition from initial drug use to compulsive drug use and addiction. The book provides a detailed overview of the pathophysiology of the disease. The information provided will be useful for neuroscientists in the field of addiction, drug abuse treatment providers, and undergraduate and postgraduate students who are interested in learning the diverse effects of drugs of abuse on the brain. Full-color circuitry diagrams of brain regions implicated in each stage of the addiction cycle Actual data figures from original sources illustrating key concepts and findings Introduction to basic neuropharmacology terms and concepts Introduction to numerous animal models used to study diverse aspects of drug use. Thorough review of extant work on the neurobiology of addiction

Neurobiology of Addiction

Neurobiology of Addiction
  • Author : George F. Koob,Michel Le Moal
  • Publisher : Elsevier
  • Release Date : 2005-11-11
  • Total pages : 504
  • ISBN : 9780080497372
  • File Size : 29,9 Mb
  • Total Download : 825

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Neurobiology of Addiction is conceived as a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction over the past 50 years. The book includes a scholarly introduction, thorough descriptions of animal models of addiction, and separate chapters on the neurobiological mechanisms of addiction for psychostimulants, opioids, alcohol, nicotine and cannabinoids. Key information is provided about the history, sources, and pharmacokinetics and psychopathology of addiction of each drug class, as well as the behavioral and neurobiological mechanism of action for each drug class at the molecular, cellular and neurocircuitry level of analysis. A chapter on neuroimaging and drug addiction provides a synthesis of exciting new data from neuroimaging in human addicts — a unique perspective unavailable from animal studies. The final chapters explore theories of addiction at the neurobiological and neuroadaptational level both from a historical and integrative perspective. The book incorporates diverse finding with an emphasis on integration and synthesis rather than discrepancies or differences in the literature. · Presents a unique perspective on addiction that emphasizes molecular, cellular and neurocircuitry changes in the transition to addiction · Synthesizes diverse findings on the neurobiology of addiction to provide a heuristic framework for future work · Features extensive documentation through numerous original figures and tables that that will be useful for understanding and teaching

Neural-Immune Interactions in Brain Function and Alcohol Related Disorders

Neural-Immune Interactions in Brain Function and Alcohol Related Disorders
  • Author : Changhai Cui,Lindsey Grandison,Antonio Noronha
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-11-14
  • Total pages : 588
  • ISBN : 9781461447290
  • File Size : 29,6 Mb
  • Total Download : 176

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Recent studies have provided clear evidence on the role of neural-immune interactions in normal brain function and neuropathological conditions. Neuroimmune factors, which play an essential role in neuroinflammatory response, have been implicated in the regulation of neuronal function and plasticity. Thus, neural-immune interactions provide a new frame work for understanding the role of the neuroimmune system in normal brain function, neurodevelopment, and a variety of neurological disorders. These advances have a far reaching impact on many areas of neuroscience, including alcohol research. Studies using human alcoholic brains, gene knockout mice, and gene expression profiling have established a clear link between alcoholism and an altered neuroimmune profile. This book integrates emerging knowledge on neural-immune interactions with key discoveries in alcohol research and provides a comprehensive overview of neural-immune interactions in brain function and behavior associated with alcohol use disorders. While Neural–Immune Interaction in Brain Function and Alcohol Related Disorders focuses on neural-immune interactions in areas directly related to alcohol use disorders, it is not intended to be all inclusive. Several areas, including sleep disorders, pain, and cholinergic anti-inflammatory pathways, are not covered as independent chapters but briefly mentioned in the text. The close relevance of these topics to neural-immune interactions and alcohol use disorders warrants future discussion and more research efforts.

Population Neuroscience

Population Neuroscience
  • Author : Tomas Paus
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-03-23
  • Total pages : 184
  • ISBN : 9783642364501
  • File Size : 35,6 Mb
  • Total Download : 545

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Is Newton’s brain different from Rembrandt’s? Does a mother’s diet during pregnancy impact brain growth? Do adolescent peers leave a signature in the social brain? Does the way we live in our middle years affect how our brains age? To answer these and many other questions, we can now turn to population neuroscience. Population neuroscience endeavors to identify environmental and genetic factors that shape the function and structure of the human brain; it uses the tools and knowledge of genetics (and the “omics” sciences), epidemiology and neuroscience. This text attempts to provide a bridge spanning these three disciplines so that their practitioners can communicate easily with each other when working together on large-scale imaging studies of the developing, mature and aging brain. By understanding the processes driving variations in brain function and structure across individuals, we will also be able to predict an individual’s risk of (or resilience against) developing a brain disorder. In the long term, the hope is that population neuroscience will lay the foundation for personalized preventive medicine and, in turn, reduce the burden associated with complex, chronic disorders of brain and body.

The Neuropharmacology of Alcohol

The Neuropharmacology of Alcohol
  • Author : Kathleen A. Grant,David M. Lovinger
  • Publisher : Springer
  • Release Date : 2019-04-08
  • Total pages : 625
  • ISBN : 3319965220
  • File Size : 27,7 Mb
  • Total Download : 324

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This volume gives an overview of new insights to alcohol pharmacology using DREADDs (Designer Receptors and Unraveling the Neuropharmacology of Alcohol). It examines which pharmacological principles should be applied to understanding DREADDs taking into account some very current research. Additionally, this book covers important topics under the heading of “experimental pharmacology” and alcohol.

Textbook of Addiction Treatment

Textbook of Addiction Treatment
  • Author : Nady el-Guebaly,Giuseppe Carrà,Marc Galanter,Alexander M. Baldacchino
  • Publisher : Springer Nature
  • Release Date : 2020-11-03
  • Total pages : 1547
  • ISBN : 9783030363918
  • File Size : 35,8 Mb
  • Total Download : 367

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Addiction is increasingly being recognized as a major global public health issue, and an ever-growing number of medical specialties, psychological and social science training programs, and professional associations are including addiction as part of their training and continuing education curricula. The first edition of this book presented an overview of the spectrum of addiction-related problems across different cultures around the globe. Sharing the experience and wisdom of more than 260 leading experts in the field, and promoted by the International Society of Addiction Medicine, it compared and contrasted clinical practices in the field of addiction medicine on the basis of neurobiological similarities as well as epidemiological and socio-cultural differences. Building on the success of this inaugural edition, and taking into account the formal and informal comments received as well as an assessment of current need, this textbook presents general updated information while retaining the most requested sections of the first edition as demonstrated by the number of chapter downloads. It also provides a basic text for those preparing for the ISAM annual certification exam. Written by some 220 international experts, it is a valuable reference resource for anyone interested in medicine, psychology, nursing, and social science.

The Prefrontal Cortex

The Prefrontal Cortex
  • Author : Joaquin M. Fuster
  • Publisher : Lippincott Williams & Wilkins
  • Release Date : 1997
  • Total pages : 364
  • ISBN : UOM:39015041356919
  • File Size : 46,6 Mb
  • Total Download : 986

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PDF book entitled The Prefrontal Cortex written by Joaquin M. Fuster and published by Lippincott Williams & Wilkins which was released on 1997 with total hardcover pages 364, the book become popular and critical acclaim.