Neurobiology Physiology And The Endocannabinoid System

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• Author : Vinood B. Patel,Victor R Preedy,Colin R Martin
• Publisher : Elsevier
• Release Date : 2023-06-24
• Total pages : 602
• ISBN : 9780323908788
• File Size : 42,9 Mb
• Total Download : 375
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Download Neurobiology and Physiology of the Endocannabinoid System in PDF, Epub, and Kindle

Neurobiology and Physiology of the Endocannabinoid System offers readers a comprehensive reference on the neurobiology of this system and the use of cannabimimetic compounds to induce neurological changes and confer symptom relief. With sections on both natural and synthetic compounds, the book's broad coverage allows readers to learn about their use with multiple conditions, as well as the working biology of the endocannabinoid system, its receptors and its ligands. This volume provides a platform for research on the effects of this system and its modulation in brain function and neurological dysfunction. Summarizes research on the working neurobiology of the endocannabinoid system Contains chapter abstracts, key facts, a dictionary and a summary Covers both natural cannabinoids and synthetic or exogenous cannabimimetics Includes conditions like headache, anxiety, stress and neuroinflammation Discusses system modulation in the context of pain, traumatic brain injury and obesity

• Author : Attila Köfalvi
• Publisher : Springer Science & Business Media
• Release Date : 2007-12-22
• Total pages : 583
• ISBN : 9780387743493
• File Size : 21,5 Mb
• Total Download : 398
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Download Cannabinoids and the Brain in PDF, Epub, and Kindle

Endocannabinoids have tremendous therapeutic potential. This book introduces readers to our current understanding of the neurobiology of endocannabinoids and related systems, detailing their pathophysiological role and therapeutic potential. Authors, experienced clinical investigators, present and analyze results of recent clinical trials as well as the development of new therapeutic strategies and medicines.

• Author : Anonim
• Publisher : Academic Press
• Release Date : 2015-11-27
• Total pages : 352
• ISBN : 9780128013762
• File Size : 27,5 Mb
• Total Download : 836
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Download Endocannabinoids in PDF, Epub, and Kindle

Endocannabinoids, the latest volume in the International Review of Neurobiology series is a comprehensive overview of the state-of-the-art research into the neurobiology of migraines. It reviews the current knowledge and understanding in the field, and provides a starting point for researchers and practitioners entering the field. Contains the expertise of contributors in the field of the neurobiology of migraines The endocannabinoid system is the biological system in the body which mediates the effects of cannabis Provides an up to date, comprehensive overview of the biological functions of endocannabinoid signaling in the brain and how it regulates an array of processes, such as brain development, reward, emotion and pain

• Author : Emmanuel S Onaivi,Takayuki Sugiura,Vincenzo Di Marzo
• Publisher : CRC Press
• Release Date : 2005-11-01
• Total pages : 592
• ISBN : 1420023640
• File Size : 27,5 Mb
• Total Download : 724
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Download Endocannabinoids in PDF, Epub, and Kindle

Over the past decade, there have been major advances in understanding the mechanisms whereby marijuana interacts with the brain in producing psychoactive and potentially therapeutic effects. The discovery of specific gene coding for cannabinoid receptors activated by smoking marijuana, and the finding of endogenous cannabinoids, which also activate the receptors, have transformed cannabinoid research into mainstream science with significant implications in human health and disease Endocannabinoids: The Brain and Body’s Marijuana and Beyond documentsadvances in the discovery and functioning of naturally occurring marijuana-like substances in human biology. It explores recent findings that point to the existence of an endocannabinoid physiological control system (EPCS) that directly impacts human development, health, and disease. While cannabinoid effects on the brain have received the greatest attention throughout the literature, this work looks at research on the endogenous cannabinoid system’s association across all of human physiology, including the immune, endocrine, and reproductive systems. With thoroughly researched and exceptionally insightful contributions from more than three-dozen top-flight researchers representing a cross-section of disciplines from molecular biology, genetics, and neurology to gynecology, physiology, and pharmacology, this work explores a range of topics as wide as the human body is complex. These topics include the EPCS’s relation to cell development and regulation, CNS function, immune function modulation, reproduction, and digestion, as well as its function in mental illness, neurodegenerative diseases, and cancer. The final section in the book considers the significance of endogenous cannabinoids found in some of the simplest multicellular organisms in the animal kingdom, as well as in mammalian cells at the earliest stages of development, all of which suggests that they play a fundamental role in human biology. Enocannabinoids: The Brain and Body’s Marijuana and Beyond explores areas that few books have ventured into, providing cutting-edge information that will ultimately help us better understand human biology at the systemic and perhaps even cellular level, as well as lead to the development of a whole new range of medications.

• Author : Dave Kendall,Stephen Alexander
• Publisher : Springer Science & Business Media
• Release Date : 2009-08-14
• Total pages : 420
• ISBN : 3540889558
• File Size : 45,5 Mb
• Total Download : 103
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Download Behavioral Neurobiology of the Endocannabinoid System in PDF, Epub, and Kindle

The endocannabinoid signaling system is a key modulator of central nervous function. This volume, essential reading for interested neuroscientists, provides in-depth coverage of the roles of the endocannabinoid signaling system in the neurobiology of behavior.

• Author : Attila Köfalvi
• Publisher : Springer
• Release Date : 2008-11-01
• Total pages : 0
• ISBN : 0387520724
• File Size : 33,8 Mb
• Total Download : 724
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Download Cannabinoids and the Brain in PDF, Epub, and Kindle

Endocannabinoids have tremendous therapeutic potential. This book introduces readers to our current understanding of the neurobiology of endocannabinoids and related systems, detailing their pathophysiological role and therapeutic potential. Authors, experienced clinical investigators, present and analyze results of recent clinical trials as well as the development of new therapeutic strategies and medicines.

• Author : Raphael Mechoulam
• Publisher : Springer Science & Business Media
• Release Date : 2006-03-30
• Total pages : 268
• ISBN : 9783764373580
• File Size : 30,8 Mb
• Total Download : 327
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Download Cannabinoids as Therapeutics in PDF, Epub, and Kindle

Only a few years ago the endocannabinoid system was unknown. Today we are aware that endocannabinoids are involved in many of the functions of the mammalian body - in neuroprotection, appetite and suckling, pain, reproduction, anxiety, memory, bone formation etc. This volume presents an up-to-date picture of some of the major fields of endocannabinoid research. It summarizes the actions of the endocannabinoids on various physiological systems and opens new therapeutic windows to a large number of diseases. The first chapter, on the use of Cannabis in India, can be viewed as an expression of thanks to the herbal practitioners, who for centuries passed on the medical traditions associated with the drug. The chapter on chemistry is a short summary of active plant, synthetic and endogenous cannabinoids being investigated today, many of which are mentioned later in the book. Cannabidiol is an unusual cannabinoid - it does not bind to the known receptors and yet exerts a variety of effects. Hence a chapter is devoted to it. Further chapters deal with the endocannabinoid system and the endocannabinoids in a variety of conditions and physiological systems. The concluding chapter describes the research done on Sativex®, a standardized plant extract, shortly to be introduced in Canada as a drug for multiple sclerosis. The intended audience is drug researchers (medicinal chemists, pharmacologists, clinicians), neuroscientists, physiologists, and clinicians interested in the effect of the endocannabinoid system in various physiological systems.

• Author : Melanie E. M. Kelly,Christian Lehmann,Juan Zhou
• Publisher : Biota Publishing
• Release Date : 2017-03-29
• Total pages : 209
• ISBN : 9781615047499
• File Size : 20,9 Mb
• Total Download : 894
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Download The Endocannabinoid System in Local and Systemic Inflammation in PDF, Epub, and Kindle

This book focuses on the role of the endocannabinoid system in local and systemic inflammation, with individual chapters written by experts in the field of cannabinoid research and medicine. The topics explore the actions of the endocannabinoid system on the immune system, including neuroinflammation in autoimmune disorders such as multiple sclerosis, and in neurodegenerative disorders such as Huntington's and Alzheimer's, as well as local and systemic inflammatory conditions affecting organs including the eye (uveitis and corneal inflammation), the bladder (interstitial cystitis), pancreas (diabetes), cardiovascular system (stroke), joints (arthritis), and sepsis. The objective of this book is to provide knowledge transfer on the use of cannabinoids in inflammatory disease by critically examining preclinical and clinical research on the immunomodulatory actions of the endocannabinoid system, with specific emphasis on the actions of cannabinoids in diseases where inflammation is a prominent component. By drawing these results together, we seek to provide further understanding of the complexities of endocannabinoid system modulation of immune function and identify potential uses and limitations for cannabinoid-based therapeutics.

• Author : Mary E. Abood,Roger G Sorensen,Nephi Stella
• Publisher : Springer Science & Business Media
• Release Date : 2012-10-04
• Total pages : 288
• ISBN : 9781461446699
• File Size : 44,7 Mb
• Total Download : 362
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Download endoCANNABINOIDS in PDF, Epub, and Kindle

This book is intended as a scientific resource for cannabinoid researchers carrying out animal and human experiments, and for those who are interested in learning about future directions in cannabinoid research. Additionally, this book may be of value to investigators currently working outside the field of cannabinoid research who have an interest in learning about these compounds and their atypical cannabinoid signalling. This book provides insight into the potential medical application of cannabinoids and their therapeutic development for the treatment of human disease.

• Author : Rajkumar Rajendram,Victor R. Preedy,Vinood B. Patel,Colin R. Martin
• Publisher : Academic Press
• Release Date : 2021-12-13
• Total pages : 458
• ISBN : 9780128206089
• File Size : 15,6 Mb
• Total Download : 420
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Download The Neurobiology, Physiology, and Psychology of Pain in PDF, Epub, and Kindle

The Neurobiology, Physiology and Psychology of Pain focuses on bettering readers’ understanding of acute and chronic pain. Featuring chapters on neurotransmitters, pharmacology, and brain imaging, this volume discusses, in detail, the mechanisms of pain and experimental studies undertaken to better understand the pathways involved. The translational work in this area has applicability for neurologists, anesthesiologists, pharmacologists, and anyone working in the intersection of these areas. This volume is integral for anyone interested in the molecular underpinnings of pain at every level. Provides comprehensive coverage on a broad range of topics related to the neuroscience of pain Contains an abstract, key facts, a mini dictionary of terms, and summary points to aid in understanding in each chapter Features chapters on molecular pathways, imaging and a deep look at behavior associated with the experience of pain Contains unique topics that will help readers navigate key areas for research and further clinical recommendations

• Author : Eric Murillo-Rodriguez
• Publisher : Academic Press
• Release Date : 2019-03-26
• Total pages : 220
• ISBN : 9780128167427
• File Size : 11,6 Mb
• Total Download : 228
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Download The Behavioral, Molecular, Pharmacological, and Clinical Basis of the Sleep-Wake Cycle in PDF, Epub, and Kindle

The Behavioral, Molecular, Pharmacological, and Clinical Basis of the Sleep-Wake Cycle provides the first comprehensive overview on the molecular methodologies used to evaluate sleep while also examining the cellular, biochemical, genetic, and therapeutic aspects of the sleep-wake cycle. There have been profound changes in the landscape of approaches to the study of sleep – mainly in the areas of molecular biology and molecular techniques. With this great focus on using multidisciplinary molecular methods, chapters address significant advances in the molecular mechanisms underlying sleep and the techniques researchers use to study this phenomenon. Written by world-leading experts in the area, this book is of great interest to researchers working in the sleep field and to anyone interested in one of the most mysterious phenomena in science – why we sleep and why we cannot survive without it. Reviews the neurobiological and cellular mechanisms of the sleep-wake cycle Provides the implications of sleep in health and disease Contrasts different techniques to study molecular mechanisms Contains case studies to better illustrate points Covers sleep disturbance and health problems involved in sleep Includes chapters on the ontogeny of sleep, along with multiple mechanisms for sleep generation

• Author : Stine Helene Falsig Pedersen
• Publisher : Springer Nature
• Release Date : 2023-01-13
• Total pages : 183
• ISBN : 9783031242045
• File Size : 44,6 Mb
• Total Download : 329
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Download Reviews of Physiology, Biochemistry and Pharmacology in PDF, Epub, and Kindle

Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.​

• Author : Mary Ellen Abood,Roger G. Pertwee
• Publisher : Springer Science & Business Media
• Release Date : 2005-03-21
• Total pages : 790
• ISBN : 354022565X
• File Size : 23,7 Mb
• Total Download : 535
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Download Cannabinoids in PDF, Epub, and Kindle

The present book is an outstanding summary of many aspects of cannabinoid research. It provides current knowledge about the pharmacology and therapeutic potential of cannabinoids as well as knowledge about the pharmacology, physiology, and pathology of the endogenous cannabinoid systems. The chapters are written by scientists who have made or are still making major contributions to the field. This book may well help generate novel ideas on how to approach the study of emotions.

• Author : Rosaria Meccariello,Rosanna Chianese
• Publisher : BoD – Books on Demand
• Release Date : 2016-06-15
• Total pages : 260
• ISBN : 9789535124290
• File Size : 25,6 Mb
• Total Download : 985
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Download Cannabinoids in Health and Disease in PDF, Epub, and Kindle

This book provides a comprehensive overview of current knowledge of cannabinoid activity in human physiology and points out the importance of endocannabinoid system for the maintenance of human health and treatment of diseases. Each chapter has been organized with the aim to cover basic concepts in the modulation of endocannabinoid system in both physiological and pathological conditions, thanks to the integration of data from experimental animal models and clinical observations. A special focus has been put on the medical use of cannabinoids and on the targeting of endocannabinoid system as new therapeutic strategy for the prevention and treatment of human diseases. Taken together, this book targets a wide audience of basic and clinical scientists, teachers and students interested in gaining a better understanding in the field of cannabinoids.

• Author : Jaime M. Monti,S. R. Pandi-Perumal,Eric Murillo-Rodríguez
• Publisher : Springer Nature
• Release Date : 2021-02-03
• Total pages : 183
• ISBN : 9783030616632
• File Size : 36,7 Mb
• Total Download : 119
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Download Cannabinoids and Sleep in PDF, Epub, and Kindle

Research on cannabis and sleep is emerging with promising results. This book offers current and comprehensive knowledge on cannabinoid research results in connection with sleep. The volume covers aspects of the hemp plant Cannabis sativa, the pharmacology of cannabinoids, neurobiology and pharmacology of sleep and wakefulness, and the benefits and side effects of cannabis on the central nervous system. It further discusses the putative therapeutical properties of cannabinoids and endocannabinoids and their potential for the treatment of sleep disorders such as insomnia, obstructive sleep apnea, REM sleep behavior disorder, and restless legs syndrome. The book is written by medical and scientific experts in this field and intended for researchers from a range of disciplines such as biomedicine, biology, neurosciences, clinical medicine, neurology, and pharmacology.

• Author : Institute of Medicine
• Publisher : National Academies Press
• Release Date : 1999-07-10
• Total pages : 288
• ISBN : 9780309071550
• File Size : 45,8 Mb
• Total Download : 985
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Download Marijuana and Medicine in PDF, Epub, and Kindle

The medical use of marijuana is surrounded by a cloud of social, political, and religious controversy, which obscures the facts that should be considered in the debate. This book summarizes what we know about marijuana from evidence-based medicineâ€"the harm it may do and the relief it may bring to patients. The book helps the reader understand not only what science has to say about medical marijuana but also the logic behind the scientific conclusions. Marijuana and Medicine addresses the science base and the therapeutic effects of marijuana use for medical conditions such as glaucoma and multiple sclerosis. It covers marijuana's mechanism of action, acute and chronic effects on health and behavior, potential adverse effects, efficacy of different delivery systems, analysis of the data about marijuana as a gateway drug, and the prospects for developing cannabinoid drugs. The book evaluates how well marijuana meets accepted standards for medicine and considers the conclusions of other blue-ribbon panels. Full of useful facts, this volume will be important to anyone interested in informed debate about the medical use of marijuana: advocates and opponents as well as policymakers, regulators, and health care providers.

• Author : Colin R Martin,Vinood B. Patel,Victor R Preedy
• Publisher : Elsevier
• Release Date : 2023-06-24
• Total pages : 672
• ISBN : 9780323901406
• File Size : 44,9 Mb
• Total Download : 730
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Download Cannabis Use, Neurobiology, Psychology, and Treatment in PDF, Epub, and Kindle

Cannabis Use, Neurobiology, Psychology, and Treatment offers readers a comprehensive reference on neurological changes, both transient and long-term, and other factors surrounding the use of these compounds and extracts. With coverage of both natural and synthetic cannabinoids, this broad coverage allows readers to learn about both adverse and non-adverse effects, including reactivity to pain, changes in behavior, and neuroactivity. This volume provides a platform for research on the effects of these compounds in brain function and neurological dysfunction. Extracts from the Cannabis sativa plant contain scores of psychoactive compounds in addition to the principal agent tetrahydrocannabinol, many of which are neuroactive. Summarizes cannabis and cannabinoid research in relation to neurological function Contains chapter abstracts, key facts, a dictionary and a summary Covers the neuroactivity of multiple Cannabis compounds beyond tetrahydrocannabinol Includes conditions like depression, anxiety, Parkinson’s, psychosis, and epilepsy Discusses brain structure and brain development, including functional connectivity

• Author : Anonim
• Publisher : Elsevier
• Release Date : 2021-01-29
• Total pages : 332
• ISBN : 9780128245682
• File Size : 22,7 Mb
• Total Download : 141
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Download 5-HT Interaction with Other Neurotransmitters: Experimental Evidence and Therapeutic Relevance Part A in PDF, Epub, and Kindle

5-HT Interaction with Other Neurotransmitters: Experimental Evidence and Therapeutic Relevance, Part B, Volume 260 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Serotonin-noradrenalin interactions, Electrophysiological and neurochemical evidence for an interaction of serotonin on noradrenergic neurons, Serotonin and cannabinoid system, 5-HT/CB interaction in the CNS in health and disease, Serotonin2A receptors and Cannabinoids, CB1/5-HT/GABA in food intake, A close interaction between serotonergic system and BDNF in the mechanism of action of antidepressant, 5-HT/ Ach, Interaction of 5-HT2A/2C ligands and nicotine, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Progress in Brain Research series Includes the latest information on the 5-HT Interaction with Other Neurotransmitters: Experimental Evidence and Therapeutic Relevance, Part B

• Author : Eric Murillo-Rodriguez
• Publisher : Academic Press
• Release Date : 2021-10-29
• Total pages : 306
• ISBN : 9780323903349
• File Size : 27,8 Mb
• Total Download : 103
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Download Methodological Approaches for Sleep and Vigilance Research in PDF, Epub, and Kindle

Methodological Approaches for Sleep and Vigilance Research examines experimental procedures used to study the sleep-wake cycle, with topics covered by world leaders in the field. The book focuses on techniques commonly used in the sleep field, including polysomnography, electrophysiology, single- and multi-unit spiking activity recording, brain stimulation, EEG power spectra, optogenetics, telemetry, and wearable and non-wearable tracking devices. Further chapters on imaging techniques, questionnaires for sleep assessment, genome-wide association studies, artificial intelligence and big data are also featured. This discussion of significant conceptual advances into experimental procedures is suitable for anyone interested in the neurobiology of sleep. Discusses current sleep research methodologies for experienced scientists Focuses on techniques that allow measurement or assessment for the sleep-wake cycle Outlines mainstream research techniques and experimental characteristics of their uses Includes polysomnography, deep brain stimulation, and more Reviews sleep-tracking devices, EEG and telemetry Covers artificial intelligence and big data in analysis

• Author : Colin R. Martin,Vinood B. Patel,Victor R Preedy
• Publisher : Elsevier
• Release Date : 2023-06-01
• Total pages : 0
• ISBN : 9780443188145
• File Size : 32,6 Mb
• Total Download : 258
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Download Cannabis, Cannabinoids, and Endocannabinoids in PDF, Epub, and Kindle

Cannabis, Cannabinoids, and Endocannabinoids offers a comprehensive reference on natural and synthetic cannabinoids, providing coverage on both adverse and non-adverse effects, including reactivity to pain, changes in behavior and neuroactivity. This volume updates on research on the effects of these compounds in brain function and neurological dysfunction, offering readers a comprehensive reference on medical usage and the symptom relief provided by these compounds. With coverage of neurological diseases like Alzheimer’s and Parkinson’s, and a wide range of other afflictions, including depression, anxiety, nausea and cancer, this broad coverage expounds on the physiological, psychological and pharmacological effects of these compounds. Unique case reports are also provided, creating a platform for research on the use of these compounds in improving patient care, brain function and neurological dysfunction. As the endocannabinoid system has been implicated in various neurological conditions, this book is a welcomed resource on the topics presented. Summarizes cannabis and cannabinoid research in relation to neurological function Covers the neuroactivity of multiple cannabis compounds beyond tetrahydrocannabinol Includes conditions like depression, anxiety, Parkinson’s, psychosis and epilepsy Discusses concepts in the context of brain structure and brain development, including functional connectivity Summarizes the medicinal usage of cannabis and cannabinoids in a variety of conditions Examines symptom control of conditions, including depression, anxiety and sleep Discusses cannabis usage in Alzheimer’s, Parkinson’s, Multiple Sclerosis, and cancer

• Author : Anonim
• Publisher : Academic Press
• Release Date : 2017-01-11
• Total pages : 378
• ISBN : 9780128119150
• File Size : 30,9 Mb
• Total Download : 120
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Download Anxiety in PDF, Epub, and Kindle

Anxiety, the latest volume in the Vitamins and Hormones series first published in 1943, and the longest-running serial published by Academic Press, provides up-to-date information on the roles that hormones and other factors play in anxiety and stress. Each volume focuses on a single molecule or disease that is related to vitamins or hormones, with the topic broadly interpreted to include related substances, such as transmitters, cytokines, growth factors, and others thoroughly reviewed. Provides cutting-edge reviews concerning the molecular and cellular biology of vitamins and hormones Contains expertise from world-renowned contributors Includes coverage of a vast array of subjects Presents in-depth, current information from the molecular to clinical level