Multiple Sclerosis

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• Author : Institute of Medicine,Board on Neuroscience and Behavioral Health,Committee on Multiple Sclerosis: Current Status and Strategies for the Future
• Publisher : National Academies Press
• Release Date : 2001-08-10
• Total pages : 457
• ISBN : 9780309072854
• File Size : 16,6 Mb
• Total Download : 387
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Download Multiple Sclerosis in PDF, Epub, and Kindle

Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives. The panel reviews existing knowledge and identifies key research questions, focusing on: Research strategies that have the greatest potential to understand the biological mechanisms of recovery and to translate findings into specific strategies for therapy. How people adapt to MS and the research needed to improve the lives of people with MS. Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others). The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families.

• Author : Alireza Minagar
• Publisher : Academic Press
• Release Date : 2015-11-09
• Total pages : 538
• ISBN : 9780128010051
• File Size : 34,9 Mb
• Total Download : 372
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Download Multiple Sclerosis in PDF, Epub, and Kindle

Multiple Sclerosis: A Mechanistic View provides a unique view of the pathophysiology of multiple sclerosis (MS) and related disorders. As the only book on the market to focus on the mechanisms of MS rather than focusing on the clinical features and treatment of the disease, it describes the role of genetic and environmental factors in the pathogenesis of MS, the role of specific cells in the pathophysiology of the disease, and the pathophysiology of inflammatory and neurodegenerative disorders related to MS. The book provides discussion of neurodegeneration and neuroregeneration, two critical emerging areas of research, as well as detailed discussion of the mechanisms of action of the approved and investigational drugs for treatment of MS and the emerging role of magnetic resonance spectroscopy (MRI) in investigations into MS. It is the only book on the market to offer comprehensive coverage of the known mechanisms of MS and related diseases, and contains contributions from physicians and researchers who are worldwide experts in the field of study. Focuses on the pathophysiologic mechanisms of multiple sclerosis and the mechanisms of action in agents for the treatment of MS Discusses the roles of neurodegeneration and neuroregeneration in MS and related diseases Authored and edited by international leaders in the field of MS research

• Author : Stella E. Hughes,Gabrielle Macaron
• Publisher : Karger Medical and Scientific Publishers
• Release Date : 2021-05-19
• Total pages : 166
• ISBN : 9783318067972
• File Size : 31,5 Mb
• Total Download : 261
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Download Fast Facts: Multiple Sclerosis in PDF, Epub, and Kindle

Multiple sclerosis (MS) is a leading cause of disability in young adults, carrying a considerable individual and societal economic burden. The development of disease-modifying therapies and updates to diagnostic criteria are leading us into a new era for MS management, both in the earliest disease phases and progressive MS. In this completely revised/fully updated edition of Fast Facts: Multiple Sclerosis, we present the most recent evidence on disease pathogenesis and all clinical aspects of the condition, as well as the latest on disease-modifying therapies and other potential treatments. Given the need for multidisciplinary management of MS, we have written this resource for the benefit of all health professionals involved in MS care. Table of Contents: • Epidemiology and genetics • Pathology • The clinical picture • Treatment of relapses and symptoms • Disease-modifying treatment • Emerging therapies • Special MS populations • Lifestyle considerations and the multidisciplinary team • Advanced MS

• Author : Stephen Waxman
• Publisher : Elsevier
• Release Date : 2005-05-27
• Total pages : 496
• ISBN : 0080489419
• File Size : 14,9 Mb
• Total Download : 139
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Download Multiple Sclerosis As A Neuronal Disease in PDF, Epub, and Kindle

This book examines the role of neurons in multiple sclerosis (MS) and the changes that occur in neurons as a result of MS. It places MS in a new and important perspective that not only explains the basis for symptom production, remission, and progress in MS, but also promises to open up new therapeutic possibilities. * Brings together the latest information from clinical, pathological, imaging, molecular, and pharmacological realms to explore the neurobiology of Multiple Sclerosis * Places MS in a new and important perspective that promises to open up new therapeutic avenues * Superbly illustrated and referenced

• Author : Howard L. Weiner,James M. Stankiewicz
• Publisher : John Wiley & Sons
• Release Date : 2012-04-23
• Total pages : 331
• ISBN : 9780470654637
• File Size : 28,6 Mb
• Total Download : 886
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Download Multiple Sclerosis in PDF, Epub, and Kindle

Designed for both neurologists and non-neurologists, Multiple Sclerosis: Diagnosis and Therapy takes a practical approach to the most current principles of diagnosis and management of this complex disease. Editors and authors from Harvard Medical School have contributed up-to-date therapeutic information for the various stages and types of MS and also provide the necessary background regarding the pathogenesis of the disease.

• Author : Sics Editore
• Publisher : SICS Editore
• Release Date : 2014-10-01
• Total pages : 229
• ISBN : 9788869308017
• File Size : 12,5 Mb
• Total Download : 529
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Download Multiple sclerosis (MS) in PDF, Epub, and Kindle

Multiple sclerosis (MS) is an autoimmune disease of unknown aetiology that affects the white matter of the central nervous system (CNS). The symptoms of multiple sclerosis are diverse, depending on the location and size of the CNS inflammatory lesions (plaques). MS is divided into subtypes: relapsing-remitting, secondary progressive and primary progressive. The relapsing-remitting form is the most common. MS is diagnosed on the basis of clinical presentation, cerebrospinal fluid (CSF) examination and magnetic resonance imaging (MRI). Pulse corticosteroid therapy is used to manage acute exacerbations. The first-line disease-modifying agents indicated for long-term therapy are interferon beta and glatiramer acetate. Natalizumab or fingolimod are used in particularly aggressive disease forms. No curative therapy exists as yet. Disease progress is individual. According to current estimations, MS decreases the patient's life expectancy by about 7 years.

• Author : Ian S. Zagon,Patricia J. McLaughlin
• Publisher : Unknown
• Release Date : 2017
• Total pages : 137
• ISBN : 0994438133
• File Size : 36,8 Mb
• Total Download : 912
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Download Multiple Sclerosis in PDF, Epub, and Kindle

PDF book entitled Multiple Sclerosis written by Ian S. Zagon,Patricia J. McLaughlin and published by Unknown which was released on 2017 with total hardcover pages 137, the book become popular and critical acclaim.

• Author : George Jelinek
• Publisher : Prof George Jelinek
• Release Date : 2010
• Total pages : 388
• ISBN : 9781742371795
• File Size : 43,9 Mb
• Total Download : 940
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Download Overcoming Multiple Sclerosis in PDF, Epub, and Kindle

Presents an overview about multiple sclerosis, proposes that lifestyle choices play a large role in its development, and offers recommendations for how to manage the disease.

• Author : Mary Rensel,Orla Gray
• Publisher : Karger Medical and Scientific Publishers
• Release Date : 2016-08-29
• Total pages : 146
• ISBN : 9781910797235
• File Size : 37,6 Mb
• Total Download : 435
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Download Fast Facts: Multiple Sclerosis in PDF, Epub, and Kindle

Since the last edition of this book, 'no evidence of disease activity' (NEDA) has been proposed as a new treatment target, early data on the first pharmacological treatments for progressive MS have emerged, and the first remyelination trial has shown positive effects on nerve repair. It is with this sense of optimism that the authors of 'Fast Facts: Multiple Sclerosis' have detailed the latest developments for use in clinical practice by all members of the multidisciplinary team, including: • a concise overview of investigations and modern diagnostic criteria • a holistic approach to all signs and symptoms, and proactive relapse management • the latest disease-modifying drugs, including when to treat, choice of drug and risk versus benefit. With case histories that will help to guide treatment decisions, discussion of the special considerations for MS during pregnancy, and in children and the elderly, and a detailed outline of emerging therapies, this book will benefit all healthcare professionals involved in the care of patients with this complex disease.

• Author : Ruth Arnon,Ariel Miller
• Publisher : Academic Press
• Release Date : 2016-05-10
• Total pages : 504
• ISBN : 9780128020074
• File Size : 15,5 Mb
• Total Download : 307
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Download Translational Neuroimmunology in Multiple Sclerosis in PDF, Epub, and Kindle

Multiple sclerosis (MS) is the most common disabling neurological disease of young adults. More than 2.3 million people are affected by MS worldwide. Symptoms can vary widely, depending on the localization and amount of the damage induced by combined inflammatory, demyelinating, and neurodegenerative processes. Although a cure for MS does not currently exist, therapies can help treat MS attacks, attenuate disease activity, reduce progress of the disease, and manage symptoms. Translational Neuroimmunology in Multiple Sclerosis provides an overview of recent findings and knowledge of the neuroimmunology of multiple sclerosis, from experimental models and the human disease to the translation of this research to immunotherapeutic strategies. Chapters describe genetic and environmental factors underlying the disease pathogenesis of MS as a basis for development of immunotherapies, immunological markers of disease activity, pharmacogenetics, and responses to therapy. Immunomodulatory therapies currently in practice and future therapeutic strategies on the horizon—such as neuroprotective strategies, stem cells, and repair promotion—are discussed. Contributed by renowned leaders in the field, this cross-disciplinary volume is a great resource for basic scientists and clinical practitioners in neuroscience, neurology, immunology, pharmacology, and in-drug development. Provides an overview of recent findings and knowledge of the neuroimmunology of multiple sclerosis and the translation of this research to immunotherapy treatment Edited by renowned leaders in the field of neuroimmunology and multiple sclerosis Contains the latest resource material for basic and clinical scientists and practitioners in neuroscience, neurology, immunology, and pharmacology

• Author : Alastair Compston,Douglas McAlpine
• Publisher : Unknown
• Release Date : 1998
• Total pages : 616
• ISBN : UOM:39015046891498
• File Size : 36,6 Mb
• Total Download : 412
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Download McAlpine's Multiple Sclerosis in PDF, Epub, and Kindle

This is the latest edition of the classic book on the subject of multiple sclerosis. An international group of authors has been involved in updating this edition which features more information on imaging and investigations, and a new chapter on neurobiology and glial development.

• Author : Ana Martinez
• Publisher : Royal Society of Chemistry
• Release Date : 2019-06-18
• Total pages : 333
• ISBN : 9781788018067
• File Size : 42,8 Mb
• Total Download : 647
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Download Emerging Drugs and Targets for Multiple Sclerosis in PDF, Epub, and Kindle

Multiple sclerosis (MS) is a complex disease with a presumed autoimmune aetiology and few current effective treatments. Disease modifying therapies focus on the altering the natural course of relapsing and remitting MS, targeting the inflammatory response. Other targets involve tacking the cause of the disease – demyelination of axons through remyelination therapies. Due to several recent breakthroughs in the understanding of the pathophysiology of MS new targets for remyelination and immunomodulation are rapidly emerging. This book provides a comprehensive overview of drug discovery and development for the molecular basis of the disease, from new targets to drugs currently in clinical development, cellular and animal disease models to biomarkers for diagnosis and assessment in clinical trials. Emerging Drugs and Targets for Multiple Sclerosis is an ideal reference for any student or researcher interested in drug development for neurodegenerative diseases, autoimmune diseases and MS in particular.

• Author : Ann Boroch
• Publisher : SCB Distributors
• Release Date : 2014-05-14
• Total pages : 222
• ISBN : 9780977344628
• File Size : 12,5 Mb
• Total Download : 136
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Download Healing Multiple Sclerosis in PDF, Epub, and Kindle

Multiple Sclerosis can now be healed and this book shows you how. Though MS is widely believed to be incurable, Boroch's breakthrough treatment protocol can dramatically restore patients to health. This landmark book describes her own tumultuous journey with MS: • Her quest for a cure • Case histories of those who have triumphed over MS • The real causes of MS • How to develop a personal treatment plan • Everything you need to bring about recovery, including a detailed and effective self-help treatment protocol • Delicious recipes and recommended foods, with two weeks of sample menus • A five-week nutritional makeover, recommended supplements and a daily sample supplement schedule • A list of recommended products • User-friendly charts and resources

• Author : Douglas S. Goodin
• Publisher : Elsevier
• Release Date : 2014-02-05
• Total pages : 736
• ISBN : 9780444633095
• File Size : 22,9 Mb
• Total Download : 534
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Download Multiple Sclerosis and Related Disorders in PDF, Epub, and Kindle

Multiple Sclerosis (MS) is generally understood to be an inflammatory autoimmune disease of the central nervous system. While we still are not certain of the root cause of MS, research results suggest that unknown environmental factors and the presence of specific genes seem the most probable targets. MS causes an inflammatory response in the central nervous system leading to neurodegeneration, oligodendrocyte death, axonal damage, and gliosis. Over the past five years ongoing research has greatly expanded our understanding of the pathogenesis of MS, detailed insight into the epidemiology and genetic factors related to MS, the introduction of new technologies and tests to better diagnose and predict the future course of the disease and the introduction of new treatments targeting MS. This collection of review chapters provides a comprehensive reference into the science and clinical applications of the latest Multiple Sclerosis research and will be a valuable resource for the neuroscience research community and the clinical neurology community of researchers and practitioners. A comprehensive tutorial reference detailing our current foundational understanding of Multiple Sclerosis Includes chapters on key topics including the genetics of MS, MRI imaging and MS, and the latest treatment options Each chapter is translational and focuses on current research and impact on diagnosis and treatment options

• Author : Jeffrey A. Cohen,Alexander Rae-Grant
• Publisher : Springer Science & Business Media
• Release Date : 2013-11-05
• Total pages : 88
• ISBN : 9781907673504
• File Size : 36,5 Mb
• Total Download : 212
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Download Handbook of Multiple Sclerosis in PDF, Epub, and Kindle

Over the past 30 years there have been significant advances in our understanding of multiple sclerosis (MS) due to the use of MRIs to better visualize the disease and because of the introduction of new ameliorating drugs. However, MS is still an incurable disease and diagnosis remains challenging for many physicians; for instance symptoms often mimic MS and there is not a specific test for the disease. To ensure optimal patient care there is a need for physicians to remain up to date with new drugs on the market, disease detection, diagnosis, and latest management options. The Handbook of Multiple Sclerosis (Second Edition) provides a concise, easily assessable guide for all healthcare professionals involved in the diagnosis and management of this condition, including standard therapies, as well as more novel treatments. The book includes comprehensive evaluations of the pharmacological treatments available, including novel investigational agents currently in development.

• Author : Lisa I. Iezzoni
• Publisher : ABC-CLIO
• Release Date : 2010
• Total pages : 214
• ISBN : 9780313365645
• File Size : 52,5 Mb
• Total Download : 616
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Download Multiple Sclerosis in PDF, Epub, and Kindle

Written for students interested in learning about multiple sclerosis, this book describes how this frequently disabling disease affects patients, exploring its effects on minds, bodies, and daily lives. Written by a professor of medicine who is also personally affected by the disease, Multiple Sclerosis offers an overview of every aspect of the condition. It begins by introducing the central nervous system and describing how multiple sclerosis affects the brain and spinal cord. The author then reviews early understanding of MS, how it was first recognized as a disease, and the discoveries that have helped explain its causes. Moving to contemporary understanding of multiple sclerosis, the book explores the epidemiology of MS in the United States and around the world, describes MS symptoms, and reviews today's treatments and research directions. Perhaps most important, it presents the experiences of persons living with multiple sclerosis, concluding with a discussion of factors affecting these individuals in their homes, families, and communities. A timeline of key discoveries and events relating to MS over the last 500 years Medical drawings and schematics showing causes and possible effects of MS A schematic map of the world showing the gradient of MS prevalence rates

• Author : Jen Powley
• Publisher : Fernwood Publishing
• Release Date : 2017-05-04T00:00:00Z
• Total pages : 229
• ISBN : 9781552669242
• File Size : 26,7 Mb
• Total Download : 588
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Download Just Jen in PDF, Epub, and Kindle

Jen Powley was diagnosed with multiple sclerosis at fifteen. By thirty-five, she had lost the use of her arms and legs. Just Jen is a powerful memoir that tells the story of Powley’s life at the time of her diagnosis, and the infinite, irrevocable ways it has changed since. Powley’s writing pulls no punches. She is lively, bold and unapologetic, answering questions people are often afraid to ask about living with a progressive disease. And yet, these snapshots from Powley’s life are not tinged with anger or despair. Just Jen is a powerful, uplifting and unforgettable work by an author who has laid her life — and her body — bare in order to survive. Just Jen: Thriving Through Multiple Sclerosis - Book Trailer 1 from Fernwood Publishing on Vimeo.

• Author : Second Edition
• Publisher : ReadHowYouWant.com
• Release Date : 2009-12
• Total pages : 174
• ISBN : 9781458748690
• File Size : 46,8 Mb
• Total Download : 742
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Download Multiple Sclerosis in PDF, Epub, and Kindle

This completely revised second edition of Multiple Sclerosis: 300 Tips for Making Life Easier contains tips, techniques, and shortcuts to help MS patients organize and simplify their lives. With over 300 tips readers will learn to conserve valuable time and energy, develop techniques for making life easier, so they can enjoy life to the fullest. From basic principles to unique solutions for saving time and energy to specific ideas, this book is packed with helpful information for those coping with the special challenges of a chronic illness. Updated chapters cover Home Safety and Accessibility, Computers and Technology, Looking Good, Feeling Better - Grooming and Dressing, Managing Mealtime, and much more. NEW sections include:. Managing medical issues Travel tips for weekend getaways or extended travel Unique product suggestions for practical helpful items that make everyday tasks easier Resource section to easily locate products and services. Multiple Sclerosis: 300 Tips for Making Life Easier, 2nd Edition is a valuable resource for individuals living with MS, family members, caregivers, and medical professionals.

• Author : Ian Robinson
• Publisher : Routledge
• Release Date : 2005-09-23
• Total pages : 160
• ISBN : 9781134987030
• File Size : 26,9 Mb
• Total Download : 842
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Download Multiple Sclerosis in PDF, Epub, and Kindle

Multiple Sclerosis affects hopes and expectations, restructures relationships, modifies careers and changes lives. It is a disease of variable onset, problematic diagnosis, unpredicatable prognosis and no effective treatment. Using unique autobiographical accounts of people with the disease, Ian Robinson sensitively portrays the difficulties and frustrations of the struggle to make sense of the clinical diagnosis and management of an illness which is effectively a way of life.

• Author : Allison Shadday
• Publisher : Hunter House
• Release Date : 2007
• Total pages : 260
• ISBN : 089793489X
• File Size : 17,8 Mb
• Total Download : 811
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Download MS and Your Feelings in PDF, Epub, and Kindle

Multiple Sclerosis is a devastating, incurable disease that afflicts about one in a thousand North Americans. Striking in the prime of life, it is the most common debilitating neurological disorder of people between the ages of 20 and 40. Eighty percent of patients suffer from cognitive impairments, seventy percent from sexual dysfunction, and fifty percent from depression. Few people are prepared for the emotional impact of this unpredictable, disabling chronic condition.

• Author : Walter George Bradley
• Publisher : Unknown
• Release Date : 2004
• Total pages : 1672
• ISBN : 0750674695
• File Size : 38,9 Mb
• Total Download : 911
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Download Neurology in Clinical Practice in PDF, Epub, and Kindle

New edition, completely rewritten, with new chapters on endovascular surgery and mitochrondrial and ion channel disorders.