Medical Innovation

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Medical Innovation

Medical Innovation
  • Author : Kevin E. Behrns,Bruce Gingles,Michael Gregory Sarr
  • Publisher : Academic Press
  • Release Date : 2018-05-24
  • Total pages : 286
  • ISBN : 9780128149270
  • File Size : 50,7 Mb
  • Total Download : 271
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Medical Innovation: Concept to Commercialization is a practical, step-by-step approach on how to move a novel concept through development to realize a commercially successful product. Real-world experience cases and knowledgeable contributors provide lessons that cover the practices of diverse organizations and multiple products. This important reference will help improve success and avoid innovation failure for translational researchers, entrepreneurs, medical school educators, biomedical engineering students and faculty, and aspiring physicians. Provides multiple considerations and comprehensive lessons from varied organizations, researchers and products Designed to help address topics that improve success and avoid the high cost of innovation failure Recommends the practical steps needed to move a novel, non-developed concept into a tangible, realistic and commercially successful product

Medical Innovation

Medical Innovation
  • Author : Davide Consoli,Andrea Mina,Richard R. Nelson,Ronnie Ramlogan
  • Publisher : Routledge
  • Release Date : 2015-10-05
  • Total pages : 186
  • ISBN : 9781317507215
  • File Size : 29,7 Mb
  • Total Download : 742
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This book brings together a collection of empirical case studies featuring a wide spectrum of medical innovation. While there is no unique pathway to successful medical innovation, recurring and distinctive features can be observed across different areas of clinical practice. This book examines why medical practice develops so unevenly across and within areas of disease, and how this relates to the underlying conditions of innovation across areas of practice. The contributions contained in this volume adopt a dynamic perspective on medical innovation based on the notion that scientific understanding, technology and clinical practice co-evolve along the co-ordinated search for solutions to medical problems. The chapters follow an historical approach to emphasise that the advancement of medical know-how is a contested, nuanced process, and that it involves a variety of knowledge bases whose evolutionary paths are rooted in the contexts in which they emerge. This book will be of interest to researchers and practitioners concerned with medical innovation, management studies and the economics of innovation. Chapter 5 of this book is freely available as a downloadable Open Access PDF at www.tandfebooks.com/openaccess. It has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 3.0 license.

You Bet Your Life

You Bet Your Life
  • Author : Paul A Offit, MD
  • Publisher : Unknown
  • Release Date : 2021-09-21
  • Total pages : 272
  • ISBN : 1541620399
  • File Size : 20,6 Mb
  • Total Download : 214
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"Four months into the coronavirus pandemic, as the death count surged, the FDA made a risky decision: it approved an anti-malarial drug as a treatment for coronavirus, despite limited data on its efficacy or side effects. A month later, the FDA withdrew its recommendation, but by then, the damage had been done. The drug was ineffective and sometimes even lethal. The mistake was hardly a one-off. As virologist Paul. A. Offit shows in You Bet Your Life, from antibiotics and vaccines to x-rays and genetic engineering, risk, and our understanding of it, have shaped the course of modern medicine, paving the way for its greatest triumphs and tragedies. By telling the stories of the events--and of the frequent hypocrisy and cravenness of the characters at their center--Offit shows how risk, and failure, have driven innovation, and importantly, how by examining our mistakes we can make better medical predictions and decisions going forward. From the outlandish origins of blood transfusions, which began with humans receiving blood for barnyard animals, to the the disastrous debut of the first polio vaccine, and the backstabbing and infighting that surrounded early gene therapies, he captures the drama that surrounds medical research, the way ego and laziness can collide with science, and ultimately how those factors should inform what we choose to do and have done to us in the clinic. The history is fascinating in its own right, but the worldwide rush to create a coronavirus vaccine only makes learning from the lessons of history essential. Weighing the uncertainties of a treatment against its potential benefits is one of medicine's greatest ethical dilemmas, and Offit examines it from every angle. He explores not just how patients and their families respond to risk but how everyone from physicians and researchers to universities and regulators do, too, and how that ultimately determines what treatments are put forward. Not everyone has the same goal. And too often the patient's health is secondary. But as Offit shows, we can all minimize risk and failure by learning how to recognize conflicts of interest, to draw inferences from animal models, and to evaluate risk, even when we have limited data. Along the way, Offit asks who should decide what risks are acceptable, and who should pay when the results are fatal. In the end, however, Offit argues that we are gambling whatever we do--and that we need to take that seriously, whether we pursue a treatment or decide to do nothing at all. The answers aren't simple, and the outcomes are life or death. Examining these questions with the compassion of a pediatrician and the rigor of a scientist, Offit reminds us that we all have a role to play in ensuring that medicine upholds its very first principle: to do no harm"--

The Business of Healthcare Innovation

The Business of Healthcare Innovation
  • Author : Lawton Robert Burns
  • Publisher : Cambridge University Press
  • Release Date : 2005-08-25
  • Total pages : 408
  • ISBN : 113944588X
  • File Size : 16,6 Mb
  • Total Download : 858
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The Business of Healthcare Innovation is the first wide-ranging analysis of business trends in the manufacturing segment of the health care industry. In this leading edge volume, Professor Burns focuses on the key role of the 'producers' as the main source of innovation in health systems. Written by professors of the Wharton School and industry executives, this book provides a detailed overview of the pharmaceutical, biotechnology, genomics/proteomics, medical device and information technology sectors. It analyses the market structures of these sectors as well as the business models and corporate strategies of firms operating within them. Most importantly, the book describes the growing convergence between these sectors and the need for executives in one sector to increasingly draw upon trends in the others. It will be essential reading for students and researchers in the field of health management, and of great interest to strategy scholars, industry practitioners and management consultants.

Purchasing Medical Innovation

Purchasing Medical Innovation
  • Author : James C. Robinson
  • Publisher : Univ of California Press
  • Release Date : 2015-03-12
  • Total pages : 184
  • ISBN : 9780520960817
  • File Size : 9,9 Mb
  • Total Download : 599
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Innovation in medical technology generates a remarkable supply of new drugs, devices, and diagnostics that improve health, reduce risks, and extend life. But these technologies are too often used on the wrong patient, in the wrong setting, or at an unaffordable price. The only way to moderate the growth in health care costs without undermining the dynamic of medical innovation is to improve the process of assessing, pricing, prescribing, and using new technologies. Purchasing Medical Innovation analyzes the contemporary revolution in the purchasing of health care technology, with a focus on the roles of the Food and Drug Administration (FDA), Medicare and private health insurers, physicians and hospitals, and consumers themselves. The FDA is more thoroughly assessing product performance under real-world conditions as well as in laboratory settings, accelerating the path to market for breakthroughs while imposing use controls on risky products. Insurers are improving their criteria for coverage and designing payment methods that reward efficiency in the selection of new treatments. Hospitals are aligning adoption of complex supplies and equipment more closely with physicians’ preferences for the best treatment for their patients. Consumers are becoming more engaged and financially accountable for their health care choices. This book describes both the strengths and deficiencies of the current system of purchasing and highlights opportunities for buyers, sellers, and users to help improve the value of medical technology: better outcomes at lower cost.

The Risks of Medical Innovation

The Risks of Medical Innovation
  • Author : Thomas Schlich,Ulrich Trohler,Ulrich Tröhler
  • Publisher : Psychology Press
  • Release Date : 2006
  • Total pages : 328
  • ISBN : 0415334810
  • File Size : 39,8 Mb
  • Total Download : 339
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Presenting a new way of thinking about the risks of medical innovation, this volume considers the issues from a social historical perspective, and studies specific cases in their respective contexts.

The Risks of Medical Innovation

The Risks of Medical Innovation
  • Author : Thomas Schlich,Ulrich Tröhler
  • Publisher : Routledge
  • Release Date : 2004-08-02
  • Total pages : 320
  • ISBN : 9781134312375
  • File Size : 34,8 Mb
  • Total Download : 974
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The risks involved in introducing new drugs and devices are amongst the most discussed issues of modern medicine. Presenting a new way of thinking about these issues, this volume considers risk and medical innovation from a social historical perspective, and studies specific cases of medical innovation, including X-rays, the pill and Thalidomide, in their respective contexts. International cases are examined through the lens of a particular set of shared questions - highlighting differences, similarities, continuities and changes, and offering a historical sociology of risk. Particularly important is the re-conceptualization of dangers in terms of risk - a numerical and probabilistic approach allowing for seemingly objective and value-neutral decisions. Read together, these papers add to our understanding of the current debate about risk and safety by providing a comparative background to the discussion, as well as a set of generally applicable criteria for analyzing and evaluating the contemporary issues surrounding medical innovation.

Global Innovation Index 2019: Creating Healthy Lives — The Future of Medical Innovation

Global Innovation Index 2019: Creating Healthy Lives — The Future of Medical Innovation
  • Author : World Intellectual Property Organization,INSEAD,Cornell University
  • Publisher : WIPO
  • Release Date : 2019-07-24
  • Total pages : 451
  • ISBN : 9791095870142
  • File Size : 37,6 Mb
  • Total Download : 649
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The Global Innovation Index 2019 provides detailed metrics about the innovation performance of 129 countries and economies around the world. Its 80 indicators explore a broad vision of innovation, including political environment, education, infrastructure and business sophistication. The GII 2019 analyzes the medical innovation landscape of the next decade, looking at how technological and non-technological medical innovation will transform the delivery of healthcare worldwide. It also explores the role and dynamics of medical innovation as it shapes the future of healthcare, and the potential influence this may have on economic growth. Chapters of the report provide more details on this year’s theme from academic, business, and particular country perspectives from leading experts and decision makers.

Medical Innovation in the Changing Healthcare Marketplace

Medical Innovation in the Changing Healthcare Marketplace
  • Author : National Research Council,Institute of Medicine,Board on Health Care Services,Policy and Global Affairs,Board on Science, Technology, and Economic Policy
  • Publisher : National Academies Press
  • Release Date : 2002-06-06
  • Total pages : 92
  • ISBN : 9780309084161
  • File Size : 33,8 Mb
  • Total Download : 902
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A wave of new health care innovation and growing demand for health care, coupled with uncertain productivity improvements, could severely challenge efforts to control future health care costs. A committee of the National Research Council and the Institute of Medicine organized a conference to examine key health care trends and their impact on medical innovation. The conference addressed the following question: In an environment of renewed concern about rising health care costs, where can public policy stimulate or remove disincentives to the development, adoption and diffusion of high-value innovation in diagnostics, therapeutics, and devices?

Medical Innovation and Disease Burden

Medical Innovation and Disease Burden
  • Author : Sobin George
  • Publisher : Cambridge University Press
  • Release Date : 2021-06-10
  • Total pages : 227
  • ISBN : 9781108832304
  • File Size : 54,7 Mb
  • Total Download : 747
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Drawing from recent concepts and data, the book carefully examines responsiveness of drug, vaccine and medical device innovations to public health priorities in India. It also emphasises the need for a responsible and responsive health innovation framework in which interests of all stakeholders are taken care of.

Second World War and the direction of medical innovation

Second World War and the direction of medical innovation
  • Author : World Intellectual Property Organization,Bhaven Sampat
  • Publisher : WIPO
  • Release Date : 2022-04-05
  • Total pages : 24
  • ISBN : 1230987654XX
  • File Size : 26,5 Mb
  • Total Download : 923
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This paper provides an overview of the role of the United States of America (U.S.) Second World War research effort on the direction of innovation, with a particular focus on medical research. It provides an overview of the U.S. wartime research program, reviews quantitative evidence on the effects of the overall wartime research shock on postwar patenting, describes the wartime medical research effort, and summarizes case studies of five major wartime medical research programs (penicillin, antimalarials, vaccines, blood substitutes, and hormones) and their effects on postwar R&D. It concludes by drawing out implications for crisis innovation and the direction of innovation in general, discussing mechanisms through which crises may have long-run effects, and highlighting hypotheses warranting further investigation.

Medical Research and Innovation

Medical Research and Innovation
  • Author : Mieczyslaw Pokorski
  • Publisher : Springer Nature
  • Release Date : 2021-03-22
  • Total pages : 101
  • ISBN : 9783030702069
  • File Size : 27,5 Mb
  • Total Download : 225
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This volume is dedicated to multidisciplinary research at the interface between basic biomedicine and clinical practice. This book guides best practice in the diagnosis and therapy while dealing with difficult-to-treat disorders of yet unclear etiology. Chapters address such disorders as granulomatosis with polyangiitis causing autoimmune-related multiorgan inflammation of blood vessels, increasingly widespread allergy to peanuts, occupational exposure to zinc oxide, and immunogenic responses to pneumococcal and influenza vaccination underlying their preventive effectiveness. Other hot issues deal with the proper use of fluid therapy in the perioperative period and a cognitive decline in lung transplant patients. A new physiotherapeutic approach of treating key myofascial trigger points in low-back pain appears highly beneficial in reducing patients’ disability, advancing physiotherapy of this overwhelming condition. Finally, other chapters consider ways to streamline medical management to increase the number of physicians and their availability for patients, a particularly sensitive issue in the current COVID-19 pandemic. The dissemination of clinical knowledge about high-risk and hardly controllable conditions is an inalienable part of progress in medical practice. The book is a resource for clinical specialists, general practitioners, and allied healthcare professionals.

The Changing Economics of Medical Technology

The Changing Economics of Medical Technology
  • Author : Institute of Medicine,Committee on Technological Innovation in Medicine
  • Publisher : National Academies Press
  • Release Date : 1991-02-01
  • Total pages : 225
  • ISBN : 9780309044912
  • File Size : 52,9 Mb
  • Total Download : 616
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Americans praise medical technology for saving lives and improving health. Yet, new technology is often cited as a key factor in skyrocketing medical costs. This volume, second in the Medical Innovation at the Crossroads series, examines how economic incentives for innovation are changing and what that means for the future of health care. Up-to-date with a wide variety of examples and case studies, this book explores how payment, patent, and regulatory policiesâ€"as well as the involvement of numerous government agenciesâ€"affect the introduction and use of new pharmaceuticals, medical devices, and surgical procedures. The volume also includes detailed comparisons of policies and patterns of technological innovation in Western Europe and Japan. This fact-filled and practical book will be of interest to economists, policymakers, health administrators, health care practitioners, and the concerned public.

Ethics of Medical Innovation, Experimentation, and Enhancement in Military and Humanitarian Contexts

Ethics of Medical Innovation, Experimentation, and Enhancement in Military and Humanitarian Contexts
  • Author : Daniel Messelken,David Winkler
  • Publisher : Springer Nature
  • Release Date : 2020-03-17
  • Total pages : 268
  • ISBN : 9783030363192
  • File Size : 51,5 Mb
  • Total Download : 465
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This book discusses ethical questions surrounding research and innovation in military and humanitarian contexts. It focuses on human enhancement in the military. Recently, the availability of medical enhancement designed to make soldiers more capable of surviving during conflict, as well as enabling them to defeat their enemies, has emerged. Innovation and medical research in military and humanitarian contexts may thus yield positive effects, but simultaneously leads to a number of highly problematic ethical issues. The work contains contributions on medical ethics that take into account the specific roles and obligations of military and humanitarian health care providers and the ethical problems they encounter. They cover different aspects of research and innovation such as vaccine development, medical enhancement, compassionate and experimental drug use, research and application of new technologies such as wearables, “Humanitarian innovation” to cope with scarce resources, Biometrics, big data, etc.The book is of interest and importance to researchers and policy makers involved with human enhancement, medical research, and innovation in military and humanitarian missions.

Voices of Innovation

Voices of Innovation
  • Author : Edward W. Marx
  • Publisher : CRC Press
  • Release Date : 2019-01-14
  • Total pages : 270
  • ISBN : 9781351650250
  • File Size : 53,6 Mb
  • Total Download : 670
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We can all point to random examples of innovation inside of healthcare information technology, but few repeatable processes exist that make innovation more routine than happenstance. How do you create and sustain a culture of innovation? What are the best practices you can refine and embed as part of your organization's DNA? What are the potential outcomes for robust healthcare transformation when we get this innovation mystery solved? Loaded with numerous case studies and stories of successful innovation projects, this book helps the reader understand how to leverage innovation to help fulfill the promise of healthcare information technology in enabling superior business and clinical outcomes.

The Diffusion of Medical Innovations

The Diffusion of Medical Innovations
  • Author : Mary L. Fennell,Richard B. Warnecke
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-03-08
  • Total pages : 300
  • ISBN : 9781468454369
  • File Size : 28,9 Mb
  • Total Download : 634
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This book has several objectives. Most basically it presents an approach to assessing interorganizational innovation diffusion. To do this we have tried to link contempo rary organizational theory with more person-centered diffusion theory. We have also combined contingency theory with the resource dependence perspective to explain why organizations might choose to initially consider an innovation, re define it to suit their particular environmental context, and then implement it. Another objective has been to examine how environmental constraints can limit the ways in which diffusion channels form, and can determine when diffusion can be truly organizational and when it will depend upon individuals. In doing so, we have tried to indicate how organizational structures emerge to manage re sources in ways that are consistent with those environmental constraints. We have borrowed the notion of boundary management from resource dependence, and we have used it to examine how organizations use various boundary management strategies to preserve their autonomy in exchange relationships with other organi zations. We have done this both at the network level and at the level of individual organizations.

Innovation in Medical Technology

Innovation in Medical Technology
  • Author : Margaret L. Eaton,Donald Kennedy
  • Publisher : JHU Press
  • Release Date : 2007-02-28
  • Total pages : 176
  • ISBN : 9780801891946
  • File Size : 22,9 Mb
  • Total Download : 267
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This work's insights into the nature and consequences of medical innovation contribute to the national debate on how best to protect patients while fostering innovation and securing benefits.

Innovative Medicine

Innovative Medicine
  • Author : Kazuwa Nakao,Nagahiro Minato,Shinji Uemoto
  • Publisher : Springer
  • Release Date : 2015-10-13
  • Total pages : 339
  • ISBN : 9784431556510
  • File Size : 47,7 Mb
  • Total Download : 334
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This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.

A Canadian Healthcare Innovation Agenda

A Canadian Healthcare Innovation Agenda
  • Author : A. Scott Carson,Kim Richard Nossal
  • Publisher : Queen's Policy Studies
  • Release Date : 2018-04-30
  • Total pages : 277
  • ISBN : 9781553395294
  • File Size : 20,7 Mb
  • Total Download : 482
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"This collection features original chapters from academics and healthcare leaders that address a range of policy issues: the meaning of healthcare innovation; how a national healthcare agency and investment fund could be governed; the nature of implications of big data and evidence; how to add value through Canadian supply-chain management; how to overcome regulatory barriers to innovation; policy innovation for indigenous, military and elderly populations; the role of the medical professions in promoting innovation, education and the development of healthcare innovators. While the Canadian healthcare system is so fragmented that many analysts argue that a system-wide strategy for healthcare innovation is a distant ideal, this book presents a contrary view by showing that Canadians do indeed have the building blocks for innovation."--Publisher's description..

Reverse Innovation in Health Care

Reverse Innovation in Health Care
  • Author : Vijay Govindarajan,Ravi Ramamurti
  • Publisher : Harvard Business Press
  • Release Date : 2018-06-19
  • Total pages : 288
  • ISBN : 9781633693678
  • File Size : 10,8 Mb
  • Total Download : 671
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Health-Care Solutions from a Distant Shore Health care in the United States and other nations is on a collision course with patient needs and economic reality. For more than a decade, leading thinkers, including Michael Porter and Clayton Christensen, have argued passionately for value-based health-care reform: replacing delivery based on volume and fee-for-service with competition based on value, as measured by patient outcomes per dollar spent. Though still a pipe dream here in the United States, this kind of value-based competition is already a reality--in India. Facing a giant population of poor, underserved people and a severe shortage of skills and capacity, some resourceful private enterprises have found a way to deliver high-quality health care, at ultra-low prices, to all patients who need it. This book shows how the innovations developed by these Indian exemplars are already being practiced by some far-sighted US providers--reversing the typical flow of innovation in the world. Govindarajan and Ramamurti, experts in the phenomenon of reverse innovation, reveal four pathways being used by health-care organizations in the United States to apply Indian-style principles to attack the exorbitant costs, uneven quality, and incomplete access to health care. With rich stories and detailed accounts of medical professionals who are putting these ideas into practice, this book shows how value-based delivery can be made to work in the United States. This "bottom-up" change doesn't require a grand plan out of Washington, DC, agreement between entrenched political parties, or coordination among all players in the health-care system. It needs entrepreneurs with innovative ideas about delivering value to patients. Reverse innovation has worked in other industries. We need it now in health care.

Innovation in Public Sector Services

Innovation in Public Sector Services
  • Author : Paul Windrum,Per M. Koch
  • Publisher : Edward Elgar Publishing
  • Release Date : 2008-01-01
  • Total pages : 264
  • ISBN : 9781848441545
  • File Size : 37,6 Mb
  • Total Download : 481
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This is a timely and important contribution on innovation processes within the public sector. Departing from the myth of private equal to entrepreneurial, public equal to bureaucratic paralysis , it offers precious insights into public sector learning, entrepreneurship, of course inertias, and also the trade-offs involved in different management philosophies and performance evaluation methods. It is a rare example of political economy done right . Giovanni Dosi, Sant Anna School of Advanced Studies, Pisa Innovation and entrepreneurship have become the cornerstones for economic growth, jobs and competitiveness in the global economy. However, the burden for generating an innovative economy has fallen on the private sector. Scholars have been remarkably taciturn concerning the role for innovation and entrepreneurship in the public sector has remained strikingly invisible. No more. In Innovation in Public Sector Services, the authors assemble a team of leading international scholars in a path breaking study to identify the potential for the public sector in contributing to innovation and entrepreneurship. In particular, the volume introduces an insightful new analytical framework that lays the foundations for transforming a sleepy public sector into a dynamic, innovative and highly effective partner for leadership and change in the global era. Scholars, policy makers and business leaders who think that the public sector is condemned to being a hindrance to innovation and entrepreneurship rather than a leader championing change and competitiveness in a global economy would be well advised to read this important new book. David B. Audretsch, Indiana University, Bloomington, US and WHU, Germany This groundbreaking book provides new key insights and opens up an important research agenda. The book develops a new taxonomy of the different types of innovation found in public sector services, and investigates the key features and drivers of public sector entrepreneurship. The book contains new statistical studies and a set of six international case studies in health and social services. The research shows that public sector organisations are important innovators in their own right. Economic growth and social development depend on efficient public sector organisations that deliver high quality services, are effectively organised, and have excellent interactions with the private sector, NGOs and citizens. Public sector innovation is complex, invariably involving changes in services, organisational structures, and managerial practices. Essential to successful innovation are the policy entrepreneurs and service entrepreneurs who develop, organise and manage new innovations. This book provides key lessons for these public sector entrepreneurs. Innovation in Public Sector Services fills a fundamental gap; explaining the dynamics of innovation and entrepreneurship in public sector services and is of great importance for researchers, academics and students interested in innovation, entrepreneurship and strategy management. It provides a stimulating read for anyone working or interested in health and social services.