Liver Regeneration

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Liver Regeneration

Liver Regeneration
  • Author : Udayan M. Apte
  • Publisher : Academic Press
  • Release Date : 2015-08-13
  • Total pages : 326
  • ISBN : 9780128004319
  • File Size : 28,9 Mb
  • Total Download : 276
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Liver Regeneration: Basic Mechanisms, Relevant Models and Clinical Applications presents cutting-edge information on liver regeneration research through an integrated, systems-wide perspective. The book addresses discoveries on hepatic progenitor cells, liver regeneration after chemical damage, and liver regeneration as a prime therapy for liver failure and disease. By addressing the urgent need for translating basic research findings into clinically relevant modalities and potential therapeutic applications, the book provides the data needed to improve liver patient management. Hundreds of full-color, graphic photographs and illustrations underline key elements and show researchers and students important aspects of liver transplantation, immunofluorescence, and other techniques used in liver regeneration. Summarizes current liver regeneration studies and discussions on expected discoveries Provides an overview of standard scientific and cutting-edge technologies to study liver regeneration Presents details on the molecular mechanisms that affect liver regeneration Highly illustrated, with hundreds of full-color, graphic photographs and illustrations to enhance the learning process

Regeneration of Liver and Kidney

Regeneration of Liver and Kidney
  • Author : Nancy L. R. Bucher,Ronald A. Malt
  • Publisher : Unknown
  • Release Date : 1971
  • Total pages : 312
  • ISBN : UOM:39015003252098
  • File Size : 12,5 Mb
  • Total Download : 570
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PDF book entitled Regeneration of Liver and Kidney written by Nancy L. R. Bucher,Ronald A. Malt and published by Unknown which was released on 1971 with total hardcover pages 312, the book become popular and critical acclaim.

The Liver

The Liver
  • Author : Irwin M. Arias,Harvey J. Alter,James L. Boyer,David E. Cohen,David A. Shafritz,Snorri S. Thorgeirsson,Allan W. Wolkoff
  • Publisher : John Wiley & Sons
  • Release Date : 2020-01-22
  • Total pages : 1144
  • ISBN : 9781119436836
  • File Size : 47,5 Mb
  • Total Download : 200
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Bridging the gap between basic scientific advances and the understanding of liver disease — the extensively revised new edition of the premier text in the field. The latest edition of The Liver: Biology and Pathobiology remains a definitive volume in the field of hepatology, relating advances in biomedical sciences and engineering to understanding of liver structure, function, and disease pathology and treatment. Contributions from leading researchers examine the cell biology of the liver, the pathobiology of liver disease, the liver’s growth, regeneration, metabolic functions, and more. Now in its sixth edition, this classic text has been exhaustively revised to reflect new discoveries in biology and their influence on diagnosing, managing, and preventing liver disease. Seventy new chapters — including substantial original sections on liver cancer and groundbreaking advances that will have significant impact on hepatology — provide comprehensive, fully up-to-date coverage of both the current state and future direction of hepatology. Topics include liver RNA structure and function, gene editing, single-cell and single-molecule genomic analyses, the molecular biology of hepatitis, drug interactions and engineered drug design, and liver disease mechanisms and therapies. Edited by globally-recognized experts in the field, this authoritative volume: Relates molecular physiology to understanding disease pathology and treatment Links the science and pathology of the liver to practical clinical applications Features 16 new “Horizons” chapters that explore new and emerging science and technology Includes plentiful full-color illustrations and figures The Liver: Biology and Pathobiology, Sixth Edition is an indispensable resource for practicing and trainee hepatologists, gastroenterologists, hepatobiliary and liver transplant surgeons, and researchers and scientists in areas including hepatology, cell and molecular biology, virology, and drug metabolism.

Innovative Medicine

Innovative Medicine
  • Author : Kazuwa Nakao,Nagahiro Minato,Shinji Uemoto
  • Publisher : Springer
  • Release Date : 2015-10-13
  • Total pages : 339
  • ISBN : 9784431556510
  • File Size : 22,9 Mb
  • Total Download : 157
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This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.

Liver Regeneration

Liver Regeneration
  • Author : Dieter Häussinger
  • Publisher : Walter de Gruyter
  • Release Date : 2011
  • Total pages : 233
  • ISBN : 9783110250787
  • File Size : 16,8 Mb
  • Total Download : 315
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understanding the mechanisms involved in liver regeneration is of crucial importance for clinical medicine, not only regarding carcinogenesis and diabetes treatment, but also for the use of stem cells for cell therapy and liver surgery. This graduate-level text provides an overview of the current state of knowledge of the molecular mechanisms of liver regeneration. Hepatic stem cells are introduced and the important players involved in regeneration such as oval cells, bone marrow and stellate cells are reviewed. The cell signaling pathways that initiate liver regeneration and regulate the switch between proliferation and apoptosis are presented and the role of liver stem cells in tumorigenesis is discussed. The book also treats the epigenetic regulation of liver stem cells and the roles of inflammation and angiogenesis in liver regeneration. This compact overview of the fascinating regenerative capacity of the liver will be of interest to graduate students and post-docs in molecular biology, biochemistry and medicine.

Liver Regeneration

Liver Regeneration
  • Author : Pedro Baptista
  • Publisher : BoD – Books on Demand
  • Release Date : 2012-05-16
  • Total pages : 266
  • ISBN : 9789535106227
  • File Size : 10,6 Mb
  • Total Download : 847
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Doctors and scientists have been aware of the "phenomenom" of liver regeneration since the time of the ancient Greeks, illustrated by the mythic tale of Prometheus' punishment. Nevertheless, true insight into its intricate mechanisms have only become available in the 20th century. Since then, the pathways and mechanisms involved in restoring the liver to its normal function after injury have been resolutely described and characterized, from the hepatic stem/progenitor cell activation and expansion to the more systemic mechanisms involving other tissues and organs like bone-marrow progenitor cell mobilization. This book describes some of the complex mechanisms involved in liver regeneration and provides examples of the most up-to-date strategies used to induce liver regeneration, both in the clinic and in the laboratory. The information presented will hopefully benefit not only professionals in the liver field, but also people in other areas of science (pharmacology, toxicology, etc) that wish to expand their knowledge of the fundamental biology that orchestrates liver injury and regeneration.

Liver Regeneration

Liver Regeneration
  • Author : D. Bernuau
  • Publisher : John Libbey Eurotext
  • Release Date : 1992
  • Total pages : 180
  • ISBN : 0861963474
  • File Size : 51,7 Mb
  • Total Download : 419
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Presents an approach to the hepatic physiology and multiple developments about cellular biology such as cell cycle regulation, growth factors and oncogenes.

Liver Regeneration and Carcinogenesis

Liver Regeneration and Carcinogenesis
  • Author : Gerard Meurant
  • Publisher : Elsevier
  • Release Date : 1995-09-27
  • Total pages : 402
  • ISBN : 0080535542
  • File Size : 43,8 Mb
  • Total Download : 424
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Because of its marked capacity to regenerate and the ability of chemical carcinogens and viruses to ready transform hepatocytes, the liver has been used extensively as a model for investigating the molecular mechanisms of cellular proliferation and carcinogenesis. Recently, striking advances have occured in the understanding of hepatocyte growth regulation and the manner in which chemical agents and viruses alter these normal growth regulatory pathways in liver carcinogenesis. This explosion of information has occured in a multitude of researh disciplines. This book brings together current findings in a coherent manner, from a molecular point of view. Three sections cover in detail the areas of liver regeneration, liver carcinogenesis, and liver tumor therapy. The contributors are pioneers and leaders in this field. * Logical organization of material in three detailed and comprehensive sections: liver regeneration, liver carcinogenesis, and liver tumor treatment * Contributors are pioneers and leaders in the field * There are currently no books on this subject on the market * Research focus is at the molecular level

Stem Cell and Liver Regeneration

Stem Cell and Liver Regeneration
  • Author : K. Okita
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Total pages : 87
  • ISBN : 9784431539711
  • File Size : 38,8 Mb
  • Total Download : 715
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Cellular therapy with liver stem cells and their progeny, including bone marrow cells, is a promising new approach that will contribute significantly to the treatment of liver diseases. The existence of the liver stem cell had long been debated, but it is now generally accepted that the liver contains cells with stem-like properties and that these cells can be activated to proliferate and differentiate into mature hepatocytes under certain conditions. There is also a substantial body of evidence to suggest that oval cells are involved in liver regeneration as they differentiate into hepatocytes and biliary cells. This book is a collection of work on stem cell and liver regeneration, initially delivered at the 14th Yamaguchi (Japan) Symposium on Liver Disease. Its nine chapters present the most recent data about basic and clinical research in hepatology in Japan and other countries, providing a valuable resource for researchers and practitioners alike.

Cardiac Regeneration

Cardiac Regeneration
  • Author : Masaki Ieda,Wolfram-Hubertus Zimmermann
  • Publisher : Springer
  • Release Date : 2017-10-27
  • Total pages : 274
  • ISBN : 9783319561066
  • File Size : 31,9 Mb
  • Total Download : 208
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This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair. Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when, why, and how heart muscle can be salvaged. The book represents a valuable resource for stem cell researchers, cardiologists, bioengineers, and biomedical scientists studying cardiac function and regeneration.

Liver Regeneration in Man

Liver Regeneration in Man
  • Author : Carroll Moton Leevy
  • Publisher : Charles C. Thomas Publisher
  • Release Date : 1973
  • Total pages : 136
  • ISBN : UOM:39015037517334
  • File Size : 48,9 Mb
  • Total Download : 141
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PDF book entitled Liver Regeneration in Man written by Carroll Moton Leevy and published by Charles C. Thomas Publisher which was released on 1973 with total hardcover pages 136, the book become popular and critical acclaim.

Drug-Induced Liver Injury

Drug-Induced Liver Injury
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2019-07-13
  • Total pages : 288
  • ISBN : 9780128173176
  • File Size : 12,5 Mb
  • Total Download : 324
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Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series

Liver Regeneration

Liver Regeneration
  • Author : Leonard I. Malkin
  • Publisher : Mss Information Corporation
  • Release Date : 1973
  • Total pages : 234
  • ISBN : UOM:39015006019734
  • File Size : 40,5 Mb
  • Total Download : 805
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PDF book entitled Liver Regeneration written by Leonard I. Malkin and published by Mss Information Corporation which was released on 1973 with total hardcover pages 234, the book become popular and critical acclaim.

Stem Cells and Cancer in Hepatology

Stem Cells and Cancer in Hepatology
  • Author : Yun-Wen Zheng
  • Publisher : Academic Press
  • Release Date : 2018-05-18
  • Total pages : 382
  • ISBN : 9780128123027
  • File Size : 33,7 Mb
  • Total Download : 545
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Stem Cells and Cancer in Hepatology: From the Essentials to Application offers basic scientists and clinicians in the fields of stem cells, hepatology and oncology an overview of the interaction between liver biology, stem cells and cancer. It discusses how the liver performs regeneration and repair, the role stem cells play in these processes, and the mechanisms by which liver cancers are initiated and developed. As the field of stem cells and cancer stem cells in hepatology is new and dynamic, thus making it difficult for researchers and clinicians to understand the most relevant historic and novel studies, this volume addresses that challenge. Addresses both the basic and clinical perspectives of the topic, including sections on normal and cancer stem cells of the liver Provides coverage of the molecular mechanisms of liver development, the proliferation of hepatic progenitor cells during development, epithelial cell plasticity, generation of hepatocytes by transdifferentiation, liver tissue engineering, and more Presents a study of hepatic stem cells that will help readers understand critical events during development, stem cell differentiation towards functional liver cell fate, and tumor initiation

Acute Liver Failure, An Issue of Clinics in Liver Disease, E-Book

Acute Liver Failure, An Issue of Clinics in Liver Disease, E-Book
  • Author : Nikolaos T. Pyrsopoulos
  • Publisher : Elsevier Health Sciences
  • Release Date : 2018-04-13
  • Total pages : 253
  • ISBN : 9780323583619
  • File Size : 14,7 Mb
  • Total Download : 824
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Dr. Pyrsopoulos has assembled the top authors in the field to provide current reviews on acute liver failure, to be the first time this topic is addressed in one volume. Topics are devoted to Classification and Epidemiologic Aspects of Acute Liver Failure; Acute Liver Failure: Mechanisms of disease and multi-systemic involvement; The Pathology of Acute Liver Failure; Liver Regeneration in the Acute Liver Failure Patient; Viral Hepatitis and Acute Liver Failure: Still a Problem; Drug- induced Liver Injury and Acute Liver Failure; Acetaminophen and Acute Liver Failure; Non-Viral Or Drug-Induced Etiologies of Acute Liver Failure; The Clinical Spectrum and Manifestations of Acute Liver Failure; Non ICU Management of Acute Liver Failure; Management of Acute Liver Failure in the ICU Setting; Prognostic Models of Acute Liver Failure; The Role of Liver Transplantation in Acute Liver Failure; and Future Approaches and Therapeutic Modalities for Acute Liver Failure. Readers will come away with a current point of view about how to approach and manage the patient with acute liver failure.

Artificial Liver Support

Artificial Liver Support
  • Author : G. Brunner,F. W. Schmidt
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Total pages : 332
  • ISBN : 9783642966293
  • File Size : 24,7 Mb
  • Total Download : 755
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The regenerative capacity of the liver cell is almost unlimited. Therefore after acute liver damage, be it viral, toxic, hypoxic, or surgical in origin, restitutio ad integrum is the usual outcome. In two forms of liver disease, however, this is not the case: in fulmi nant hepatic failure, liver regeneration often is not fast enough to keep the organism alive; in end-stage cirrhosis, regeneration is dis turbed by a hypertrophic architecture of fibrotic tissue. For these extreme forms of liver disease and for critical situations before and after liver surgery, artificial liver support is needed. This book contains the latest results in this area of research pre sented by scientists from allover the world at an international symposium held in Celle, Germany, June 2-4, 1980. Exciting new methods like continuous membrane plasma sepa ration and liver cell transplantation into the spleen have been de veloped. The older methods of hemoperfusion and dialysis have been improved. Enzymological methods and liver transplantation have made good progress. We hope that this volume will help the clinician in his decision-making and stimulate ingenious new re search for the benefit of our liver patients.

MicroRNA in Regenerative Medicine

MicroRNA in Regenerative Medicine
  • Author : Chandan K. Sen
  • Publisher : Academic Press
  • Release Date : 2023-05-26
  • Total pages : 1134
  • ISBN : 9780128207222
  • File Size : 52,5 Mb
  • Total Download : 489
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Regulating virtually all biological processes, the genome’s 2,654 newly discovered variants of mature microRNAs – short ribonucleic acid molecules found in eukaryotic cells – hold a key role in the body’s toolkit of regenerative and reparative capacities. Identifying how to activate and deliver these specialist molecules may aid in the repair and regeneration of major tissue and organ damage in future therapies. In MicroRNA and Regenerative Medicine, Second Edition, over 50 leading experts address foundational and emerging topics in the field. Concisely summarizing and evaluating key findings from new research and their translational application, contributors examine current and future significance of clinical research in the miRNA area. Coverage encompasses all major aspects of fundamental stem cell and developmental biology, including the uses of miRNA in cell and tissue plasticity, developmental biology, tissue repair, and regeneration. In particular, contributors provide focused coverage of methodologies for regenerative intervention and tissue engineering. Topics new to this edition include proteomic changes during tissue repair and regeneration, horizontal transfer of miRNAs in tissue regeneration, tissue stemness, peripheral nerve regeneration, miRNA as biomarkers, microRNA in pregnancy and embryo development, exogenous and diet derived microRNA in tissue development, ocular microRNA, mitochondrial microRNA, sensory hair cell death and regeneration, and microRNA in senescence. Features chapter contributions from international leaders in the field, covering the spectrum from bench to bedside Includes short, applied chapters offering focused discussion and practical examples Incorporates multi-color text layout with more than 150 color figures to illustrate important findings

Growth, Proliferation, and Apoptosis in Hepatocytes

Growth, Proliferation, and Apoptosis in Hepatocytes
  • Author : Kiwamu Okita
  • Publisher : Springer Science & Business Media
  • Release Date : 2002
  • Total pages : 120
  • ISBN : 4431703233
  • File Size : 47,7 Mb
  • Total Download : 246
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To gain a better understanding of the pathology of liver disease, the signaling system controlling hepatocyte differentiation, proliferation, and apoptosis was selected as the theme of the 12th Yamaguchi Symposium on Liver Diseases. Ten leading researchers presented their latest experimental results. Focusing on apoptosis, guest speaker Professor D.A. Brenner, USA, spoke on the regulation of tumor necrosis factor alpha and Fas ligand-induced hepatic apoptosis by nerve factor-kappa B. Other researchers covered the molecular basis for clonal deletion therapy in hepatocellular carcinoma, hepatitis C virus induction of proliferation signals, helix-loop-helix protein in liver-specific gene expression, and reconstitution of hepatic tissues using liver stem cells, among other topics of current interest. These proceedings thus serve as a useful resource for all involved in hepatology research.

Split liver transplantation

Split liver transplantation
  • Author : X. Rogiers,H. Bismuth,R.W. Busuttil,D.C. Broering,D. Azoulay
  • Publisher : Springer Science & Business Media
  • Release Date : 2002-08
  • Total pages : 182
  • ISBN : 3798512566
  • File Size : 47,8 Mb
  • Total Download : 707
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Aimed at the trainee surgeon and experienced transplant surgeon, this compendium on split-liver grafting contains articles written by faculty members of the first International Course on Split-Liver Transplantation. It covers the main aspects of the field and is geared towards helping surgeons select the best surgical techniques as well as identifying the pitfalls. The text features detailed instructions on the various procedures as well as an overview of the area.

AMB

AMB
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1995
  • Total pages : 274
  • ISBN : UCLA:L0076004977
  • File Size : 35,8 Mb
  • Total Download : 642
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PDF book entitled AMB written by Anonim and published by Unknown which was released on 1995 with total hardcover pages 274, the book become popular and critical acclaim.

Principles of Regenerative Medicine

Principles of Regenerative Medicine
  • Author : Anthony Atala,Robert Lanza,James A. Thomson,Robert Nerem
  • Publisher : Academic Press
  • Release Date : 2010-12-16
  • Total pages : 1202
  • ISBN : 0123814235
  • File Size : 45,9 Mb
  • Total Download : 785
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Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine New discoveries from leading researchers on restoration of diseased tissues and organs