Green Synthetic Approaches For Biologically Relevant Heterocycles
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Green Synthetic Approaches for Biologically Relevant Heterocycles
- Author : Goutam Brahmachari
- Publisher : Elsevier
- Release Date : 2021-03-20
- Total pages : 646
- ISBN : 9780323851305
- File Size : 30,9 Mb
- Total Download : 316
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Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume One: Advanced Synthetic Techniques reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume One explores advanced synthetic techniques, with each chapter presenting in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles that are classified on the basis of ring-size and/or the presence of heteroatoms. Techniques covered range from high pressure cycloaddition reactions and microwave irradiation to sustainable one-pot domino reactions. This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry. Provides fully updated coverage of the field of greener heterocycle synthesis Includes new chapters on varied multicomponent reactions, alongside both traditional and novel approaches Presents information in an accessible style with an emphasis on sustainability
Green Synthetic Approaches for Biologically Relevant Heterocycles
- Author : Goutam Brahmachari
- Publisher : Elsevier
- Release Date : 2021-02-26
- Total pages : 822
- ISBN : 9780323851336
- File Size : 24,8 Mb
- Total Download : 402
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Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume Two: Green Catalytic Systems and Solvents reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume Two explores green catalytic systems and solvents and the techniques surrounding this approach, including metal and magnetic catalysis to organocatalysis and solid acid catalysis, cycloaddition reactions, and varied approaches using ionic liquids. This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry. Provides fully updated coverage of the field with an emphasis on sustainability Highlights a range of different eco-friendly solvents and environmentally-friendly catalysts Collates the experience of a global team of expert contributors
Green Synthetic Approaches for Biologically Relevant Heterocycles

- Author : Goutam Brahmachari
- Publisher : Unknown
- Release Date : 2021
- Total pages : 229
- ISBN : OCLC:1240807230
- File Size : 37,5 Mb
- Total Download : 604
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Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume Two: Green Catalytic Systems and Solvents reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume Two explores green catalytic systems and solvents and the techniques surrounding this approach, including metal and magnetic catalysis to organocatalysis and solid acid catalysis, cycloaddition reactions, and varied approaches using ionic liquids. This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry.
Green Synthetic Processes and Procedures
- Author : Roberto Ballini
- Publisher : Royal Society of Chemistry
- Release Date : 2019-06-27
- Total pages : 413
- ISBN : 9781788018395
- File Size : 54,5 Mb
- Total Download : 656
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The principles of Green Chemistry aim to improve the sustainability of chemical processes and reduce the generation of hazardous substances. There has been great growth in the field over the past few years and the number of research groups working in this area is still increasing. Now one of the biggest challenges is to embed the Green Chemistry ideals of safety and sustainability as standard, both in industry and academia. In order to do this, it is important to create resources that detail different applications and approaches. Green Synthetic Processes and Procedures brings together expert contributors from across a number of areas of green synthesis to cover a diverse array of subjects. Providing a thorough overview of the current green synthetic toolbox, from biocatalysis to sonochemistry, this book is a useful resource for any chemist wishing to design cleaner and safer processes.
Organophosphorus Chemistry
- Author : John C. Tebby,David Loakes,David W. Allen
- Publisher : Royal Society of Chemistry
- Release Date : 2018-04-13
- Total pages : 462
- ISBN : 9781788011679
- File Size : 21,6 Mb
- Total Download : 562
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Coverage in this annual review of the literature presents a comprehensive and critical survey of the vast field of study involving organophosphorus compounds. From phosphines and related P-C bonded compounds through tervalent phosphorus acid derivatives, phosphine chalcogenides, and recent developments in green synthetic approaches in organophosphorus chemistry, the volume reflects established and current interests in the area. With an emphasis on interdisciplinary content, this book is aimed at the worldwide organic chemistry and engineering research communities.
Green Chemistry: Synthesis of Bioactive Heterocycles
- Author : K. L. Ameta,Anshu Dandia
- Publisher : Springer
- Release Date : 2014-06-17
- Total pages : 412
- ISBN : 9788132218500
- File Size : 16,8 Mb
- Total Download : 754
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The book presents a succinct summary of methods for the synthesis and biological activities of various different-sized bioactive heterocycles using different green chemistry synthetic methodologies, like microwave, ultrasonic, water mediated, ionic liquids, etc. The book also provides an insight of how green chemistry techniques are specific to the bioactive heterocyclic compounds.
N-Sulfonated-N-Heterocycles
- Author : Galal H. Elgemeie,Rasha A. Azzam,Wafaa A. Zaghary,Ashraf A. Aly,Nadia H Metwally,Mona O. Sarhan,Elshimaa M. Abdelhafez,Rasha E. Elsayed
- Publisher : Elsevier
- Release Date : 2022-08-26
- Total pages : 523
- ISBN : 9780128221822
- File Size : 12,8 Mb
- Total Download : 235
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N-Sulfonated-N-Heterocycles covers the synthesis, chemistry and biological applications of these compounds, focusing on pioneering synthetic approaches, mechanistic insights and their limitations, as well as recent advances in this field. The synthesis of some of N-sulfonated N-heterocycles and their transformation to other useful cyclic and acyclic compounds are discussed, as well as their uses as useful intermediates in the preparation of polymeric and medicinal materials. This book includes detailed methods and protocols, and the focus on applications makes this resource an essential guide for all researchers in the area of organic, medicinal and polymeric synthetic study. Reviews the use of N-sulfonated N-heterocycles as important precursors for the synthesis of biologically active compounds Includes information on synthetically useful transformations of N-sulfonated N-heterocycles Covers a wide synthetic methods used for an important branch of heterocycles and their biological evaluation in detail Features over 500 schemes to illustrate different synthetic pathways and reactions of N-sulfonated N-heterocycles
Organophosphorus Chemistry: Volume 50
- Author : John C. Tebby,David W. Allen,Lee J. Higham
- Publisher : Royal Society of Chemistry
- Release Date : 2021-07-30
- Total pages : 505
- ISBN : 9781839162053
- File Size : 27,8 Mb
- Total Download : 642
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This annual review of the literature presents a comprehensive and critical survey of the vast field of study involving organophosphorus compounds.
N-Heterocycles
- Author : Keshav Lalit Ameta,Ravi Kant,Andrea Penoni,Angelo Maspero,Luca Scapinello
- Publisher : Springer Nature
- Release Date : 2022-05-25
- Total pages : 459
- ISBN : 9789811908323
- File Size : 29,8 Mb
- Total Download : 901
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This book presents an overview of the recent advancements for the synthesis of small- and medium-sized azaheterocycles, including pyrroles, indoles, pyrimidines, pyridines, pyrrolidines, imidazoles, pyrazoles, pyrazolines, lactams, and 1,2,3-triazoles, which are significant scaffolds for compounds with pharmaceutical uses. The book also discusses various properties and performance attributes of azaheterocycles including their bioactivity and synthetic strategies. Given the contents, the book will be a valuable reference for students, researchers, and professionals interested in organic synthesis and medicinal chemistry.
Alternative Energy Sources for Green Chemistry
- Author : Georgios Stefanidis,Andrzej Stankiewicz
- Publisher : Royal Society of Chemistry
- Release Date : 2016-08-24
- Total pages : 428
- ISBN : 9781782623632
- File Size : 43,5 Mb
- Total Download : 329
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The use of alternative energy forms and transfer mechanisms is one of the key approaches of process intensification. In recent years, significant amounts of research have been carried out in developing chemical processing technologies enhanced by plasma, electric and magnetic fields, electromagnetic and ultra-sound waves and high gravity fields. Discussing the broad impact of alternative energy transfer technologies on reactions, separations and materials synthesis, this book reports on recent breakthrough results in various application areas. It provides a comprehensive overview of the current developments in the field. The book enables industrialists, academics and postgraduates in alternative-energy based processing to see the potential of alternative energies for green chemistry and sustainability of chemical manufacturing.
Green Synthesis of Heterocycles
- Author : Fabio Arico,Oliver Reiser
- Publisher : Frontiers Media SA
- Release Date : 2020-03-09
- Total pages : 95
- ISBN : 9782889635849
- File Size : 26,8 Mb
- Total Download : 461
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PDF book entitled Green Synthesis of Heterocycles written by Fabio Arico,Oliver Reiser and published by Frontiers Media SA which was released on 2020-03-09 with total hardcover pages 95, the book become popular and critical acclaim.
Green Approaches in Medicinal Chemistry for Sustainable Drug Design
- Author : Bimal K. Banik
- Publisher : Elsevier
- Release Date : 2020-03-27
- Total pages : 1044
- ISBN : 9780128175934
- File Size : 51,7 Mb
- Total Download : 896
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Extensive experimentation and high failure rates are a well-recognised downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry reveals how medicinal and green chemistry can work together to directly address this issue. After providing essential context to the growth of green chemistry in relation to drug discovery in Part 1, the book goes on to identify a broad range of practical methods and synthesis techniques in Part 2. Part 3 reveals how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process, whilst Parts 4 and 5 discuss natural products and microwave-induced chemistry. Finally, the role of computers in drug discovery is explored in Part 6. Identifies novel and cost effective green medicinal chemistry approaches for improved efficiency and sustainability Reflects on techniques for a broad range of compounds and materials Highlights sustainable and green chemistry pathways for molecular synthesis
Multicomponent Reactions towards Heterocycles
- Author : Erik Van der Eycken,Upendra K. Sharma
- Publisher : John Wiley & Sons
- Release Date : 2021-11-22
- Total pages : 624
- ISBN : 9783527832446
- File Size : 33,5 Mb
- Total Download : 488
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Presents a wide-ranging overview of essential topics and recent advances in MCR chemistry Heterocycles are a central component in natural product chemistry, pharmaceuticals, agrochemicals, and material science. New synthetic methodologies integrating the sequencing of multicomponent reactions (MCRs) are today being used for the rapid synthesis of diversified heterocycles in just one step. Multicomponent Reactions towards Heterocycles presents an up-to-date summary MCR chemistry with a focus on the conjugation between modern synthetic methodologies and MCRs. Featuring contributions by leaders in the field, this comprehensive resource highlights applications of MCRs in natural products and intermediate synthesis, discusses current trends and future prospects in MCR chemistry, outlines novel multicomponent procedures, and more. The authors provide the practical information required for designing new reaction strategies and mechanisms, covering topics including MCR-based green synthetic methods, cyclization and cycloaddition reactions, heterocycle multicomponent syntheses in a continuous flow, catalytic alkynoyl generation, MCR synthesis of saturated heterocycles, and C–H functionalization and multicomponent reactions. Provides a thorough overview of heterocycles as input in multicomponent reactions Discusses recent advances in the field of MCR chemistry and progress in the synthesis and functionalization of heterocycles Demonstrates the use of MCRs to simplify synthetic design and achieve complexity and diversity in novel bioactive molecules Highlights examples of multicomponent polymerizations, target-oriented synthesis, and applications of MCR in medicinal chemistry Explains the methodology of using on-resin MCRs to produce heterocycle compounds Illustrating the key role of MCRs towards heterocycles in natural product synthesis, drug discovery, organic synthesis, and other applications, Multicomponent Reactions towards Heterocycles is required reading for synthetic chemists in academia and industry alike.
Modern Green Chemistry and Heterocyclic Compounds
- Author : Ravindra S. Shinde,A. K. Haghi
- Publisher : CRC Press
- Release Date : 2020-07-01
- Total pages : 302
- ISBN : 9781000029192
- File Size : 24,5 Mb
- Total Download : 476
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This book covers the general properties of heterocyclic compounds and methods for their preparation to use in applications of green chemistry. Heterocyclic compounds are an important class of molecules in organic chemistry due to their presence in natural products and their use in pharmaceuticals and new materials. They also play a vital role in the metabolism of living cells. Heterocyclic compounds have a wide range of applications in agrochemicals, pharmaceuticals, veterinary products, etc. This research-oriented volume is ideal for readers who want to fully realize the almost limitless potential of heterocyclic compounds and to discover new and effective pharmaceuticals among heterocyclic compounds, the largest and most varied family of organic compounds. The book features several case studies and step-by-step descriptions of synthetic methods and practical techniques. It also serves as a guide for chemists, offering them new insights and new paths to explore for effective drug discovery.
Organochalcogen Compounds
- Author : Eder João Lenardão,Claudio Santi,Gelson Perin,Diego Alves
- Publisher : Elsevier
- Release Date : 2022-05-27
- Total pages : 340
- ISBN : 9780128194508
- File Size : 25,9 Mb
- Total Download : 539
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Organochalcogen Compounds: Synthesis, Catalysis and New Protocols with Greener Perspectives, in the Advances in Green and Sustainable Chemistry series, reviews the state-of-the-art in new green protocols involving organochalcogen compounds (Se, S and Te), including the use of non-conventional reaction media, alternative solvents and solvent-free protocols to prepare these important compounds. The book provides an authoritative overview of the current state of the field and compiles recent advances in methodologies for the application of green chemistry principles in compound development, including the use of organochalcogen compounds as intermediates, catalysts or target products across a range of applications. The recent developments outlined in the book reflect the efforts of researchers in this area to move towards a more sustainable chemistry, giving the book the dual benefit of highlighting the latest developments in the field. Highlights green synthetic methods with potential application in the synthesis of natural compounds or other biologically active scaffolds Explores the chemical modification of natural compounds by insertion of organochalcogen groups for the preparation of boosted bioactive semisynthetic molecules Discusses how redox catalysis and catalysis in flow conditions using eco-friendly oxidant can provide new opportunities for the synthesis of linear ad cyclic derivatives
Bio-Based Solvents
- Author : François Jérôme,Rafael Luque
- Publisher : John Wiley & Sons
- Release Date : 2017-06-29
- Total pages : 200
- ISBN : 9781119065449
- File Size : 27,6 Mb
- Total Download : 127
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A multidisciplinary overview of bio-derived solvent applications, life cycle analysis, and strategies required for industrial commercialization This book provides the first and only comprehensive review of the state-of-the-science in bio-derived solvents. Drawing on their own pioneering work in the field, as well as an exhaustive survey of the world literature on the subject, the authors cover all the bases—from bio-derived solvent applications to life cycle analysis to strategies for industrial commercialization—for researchers and professional chemists working across a range of industries. In the increasingly critical area of sustainable chemistry, the search for new and better green solvents has become a top priority. Thanks to their renewability, biodegradability and low toxicity, as well as their potential to promote advantageous organic reactions, green solvents offer the promise of significantly reducing the pernicious effects of chemical processes on human health and the environment. Following an overview of the current solvents markets and the challenges and opportunities presented by bio-derived solvents, a series of dedicated chapters cover all significant classes of solvent arranged by origin and/or chemical structure. Throughout, real-world examples are used to help demonstrate the various advantages, drawbacks, and limitations of each class of solvent. Topics covered include: The commercial potential of various renewably sourced solvents, such as glycerol The various advantages and disadvantages of bio-derived versus petroleum-based solvents Renewably-sourced and waste-derived solvents in the design of eco-efficient processes Life cycle assessment and predictive methods for bio-based solvents Industrial and commercial viability of bio-based solvents now and in the years ahead Potential and limitations of methodologies involving bio-derived solvents New developments and emerging trends in the field and the shape of things to come Considering the vast potential for new and better products suggested by recent developments in this exciting field, Bio-Based Solvents will be a welcome resource among students and researchers in catalysis, organic synthesis, electrochemistry, and pharmaceuticals, as well as industrial chemists involved in manufacturing processes and formulation, and policy makers.
Multicomponent Reactions
- Author : K.L. Ameta, Ph.D.,Anshu Dandia
- Publisher : CRC Press
- Release Date : 2017-09-20
- Total pages : 598
- ISBN : 9781315352732
- File Size : 40,6 Mb
- Total Download : 493
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This timely book provides a succinct summary of methods for the synthesis of bioactive heterocycles using a multicomponent reaction (MCR) approach. The majority of pharmaceuticals and biologically active agrochemicals are heterocycles while countless additives and modifiers used in industrial applications are heterocyclic in nature. With the recent introduction of high-throughput biological evaluation, the importance of MCRs for drug discovery has been recognized and considerable efforts have been focused especially on the design and development of multi-component procedures for the generation of various bioactive heterocycles due to their significant therapeutic potential.
Room Temperature Organic Synthesis
- Author : Goutam Brahmachari
- Publisher : Elsevier
- Release Date : 2015-03-19
- Total pages : 386
- ISBN : 9780128011386
- File Size : 39,5 Mb
- Total Download : 218
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Filling a gap in the scientific literature, Room Temperature Organic Synthesis is unique in its authoritative, thorough, and applied coverage of a wide variety of "green" organic synthetic methodologies. The book describes practical, feasible protocols for room temperature reactions to produce carbon-carbon and carbon-heteroatom bond formations including aliphatic, aromatic, alicyclic, heterocycles, and more. Consistently organized for easy access, each selected reaction is discussed in a very compact and structured manner including: reaction type, reaction condition, reaction strategy, catalyst, keywords, general reaction scheme, mechanism (in selected cases), representative entries, experimental procedure, characterization data of representative entries, and references. This book will be a valuable resource for synthetic organic, natural products, medicinal, and biochemists as well as those working in the pharmaceutical and agrochemical industry. Includes more than 300 protocols for a green approach to organic synthesis Provides specific detail about experimental conditions Increases efficiency in the laboratory by eliminating time-consuming literature searches
Dendrimer Chemistry
- Author : Michael Malkoch,Sandra García Gallego
- Publisher : Royal Society of Chemistry
- Release Date : 2020
- Total pages : 327
- ISBN : 9781788011327
- File Size : 29,7 Mb
- Total Download : 929
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An overview of the latest advances in the synthesis, characterization and applications of dendrimers and other complex dendritic architectures.
Bioactive Heterocyclic Compound Classes
- Author : Clemens Lamberth,Jürgen Dinges
- Publisher : John Wiley & Sons
- Release Date : 2012-08-16
- Total pages : 372
- ISBN : 9783527664474
- File Size : 28,8 Mb
- Total Download : 878
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The chemistry of heterocycles is an important branch of organic chemistry. This is due to the fact that a large number of natural products, e. g. hormones, antibiotics, vitamins, etc. are composed of heterocyclic structures. Often, these compounds show beneficial properties and are therefore applied as pharmaceuticals to treat diseases or as insecticides, herbicides or fungicides in crop protection. This volume presents important pharmaceuticals. Each of the 20 chapters covers in a concise manner one class of heterocycles, clearly structuredas follows: * Structural formulas of most important examples (market products) * Short background of history or discovery * Typical syntheses of important examples * Mode of action * Characteristic biological activity * Structure-activity relationship * Additional chemistry information (e.g. further transformations, alternative syntheses, metabolic pathways, etc.) * References. A valuable one-stop reference source for researchers in academia and industry as well as for graduate students with career aspirations in the pharmaceutical chemistry.
Bioactive Heterocycles II
- Author : Shoji Eguchi
- Publisher : Springer
- Release Date : 2007-10-08
- Total pages : 309
- ISBN : 9783540725923
- File Size : 50,6 Mb
- Total Download : 574
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With contributions by numerous experts