Genetic Control Of Malaria And Dengue

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• Author : Zach N. Adelman
• Publisher : Academic Press
• Release Date : 2015-10-15
• Total pages : 486
• ISBN : 9780128004050
• File Size : 51,8 Mb
• Total Download : 909
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Download Genetic Control of Malaria and Dengue in PDF, Epub, and Kindle

Genetic Control of Malaria and Dengue focuses on the knowledge, technology, regulation and ethics of using genetically modified mosquitoes to interrupt the transmission of important vector-borne diseases including Malaria. It contains coverage of the current state of knowledge of vector-borne diseases and how they are currently controlled; vaccine, drug and insecticide development; various strategies for altering the genome of mosquitoes in beneficial ways; and the regulatory, ethical and social environment concerning these strategies. For more than five decades, the prospect of using genetically-modified mosquitoes to control vector-borne disease transmission has been a purely hypothetical scenario. We simply did not have the technology or basic knowledge to be able to do it. With the explosion of field trials and potential interventions in development, Genetic Control of Malaria and Dengue provides a comprehensive overview of research in genetics, microbiology, virology, and ecology involved in the development and implementation of genetic modification programs for virus and disease control. This book is meant to provide a practical guide to researchers, regulators and the general public about how this technology actually works, how it can be improved, and what is still unknown. Includes coverage of vectorial capacity, critical to understanding vector-borne disease transmission Provides a summary of the concepts of both population suppression and population replacement Contains pivotal coverage of ethical and ecological ramifications of genetics-based control strategies

• Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Global Health,Forum on Microbial Threats
• Publisher : National Academies Press
• Release Date : 2016-09-21
• Total pages : 396
• ISBN : 9780309377621
• File Size : 32,9 Mb
• Total Download : 609
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Download Global Health Impacts of Vector-Borne Diseases in PDF, Epub, and Kindle

Pathogens transmitted among humans, animals, or plants by insects and arthropod vectors have been responsible for significant morbidity and mortality throughout recorded history. Such vector-borne diseases â€" including malaria, dengue, yellow fever, and plague â€" together accounted for more human disease and death in the 17th through early 20th centuries than all other causes combined. Over the past three decades, previously controlled vector-borne diseases have resurged or reemerged in new geographic locations, and several newly identified pathogens and vectors have triggered disease outbreaks in plants and animals, including humans. Domestic and international capabilities to detect, identify, and effectively respond to vector-borne diseases are limited. Few vaccines have been developed against vector-borne pathogens. At the same time, drug resistance has developed in vector-borne pathogens while their vectors are increasingly resistant to insecticide controls. Furthermore, the ranks of scientists trained to conduct research in key fields including medical entomology, vector ecology, and tropical medicine have dwindled, threatening prospects for addressing vector-borne diseases now and in the future. In June 2007, as these circumstances became alarmingly apparent, the Forum on Microbial Threats hosted a workshop to explore the dynamic relationships among host, pathogen(s), vector(s), and ecosystems that characterize vector-borne diseases. Revisiting this topic in September 2014, the Forum organized a workshop to examine trends and patterns in the incidence and prevalence of vector-borne diseases in an increasingly interconnected and ecologically disturbed world, as well as recent developments to meet these dynamic threats. Participants examined the emergence and global movement of vector-borne diseases, research priorities for understanding their biology and ecology, and global preparedness for and progress toward their prevention, control, and mitigation. This report summarizes the presentations and discussions from the workshop.

• Author : Graciela R. Ostera,Lawrence O. Gostin
• Publisher : Unknown
• Release Date : 2014
• Total pages : 0
• ISBN : OCLC:1376472455
• File Size : 28,9 Mb
• Total Download : 371
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Download Biosafety Concerns Involving Genetically Modified Mosquitoes to Combat Malaria and Dengue in Developing Countries in PDF, Epub, and Kindle

Malaria and dengue are the most prevalent mosquito-borne infections worldwide. Because traditional vector control methods have proven to be insufficient to control mosquito populations in endemic areas, scientists are actively working in the design of new strategies, such as genetically modified (GM) mosquitoes, to reduce disease transmission. The replacement of natural populations with GM mosquitoes is becoming a tangible possibility, however, many fear that the release of these organisms into the environment could constitute a significant risk to biodiversity and may cause the unintended spread of GM organisms across national borders. The Cartagena Protocol on Biosafety, an international agreement originally intended to oversee the trade of GM crops, did not include specific provisions for the safe use of GM insects. Recently, the Ad Hoc Technical Expert Group (AHTEG) on Risk Assessment and Risk Management to the Conference of the Parties, provided guidelines on the use of GM arthropods for the control of human disease. However, these guidelines did not address some significant technical and safety issues associated with the use of genetically or biologically modified vectors. A new global treaty, specifically intended to address issues related to genetic or biological modifications of arthropod vectors seem to be necessary before we endorse the decision of releasing modified arthropod vectors into the natural environment.

• Author : Brij Kishore Tyagi
• Publisher : Springer Nature
• Release Date : 2022-01-01
• Total pages : 455
• ISBN : 9789811629648
• File Size : 26,5 Mb
• Total Download : 575
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Download Genetically Modified and other Innovative Vector Control Technologies in PDF, Epub, and Kindle

This book comprehensively covers the latest development in developing and deploying the genetically modified vectors, particularly Anopheles and Aedes mosquitoes responsible for transmitting malaria parasites and dengue viruses, the most deadly and/or debilitating among all the vector-borne diseases. It is considered timely and commensurate to bring about a book dealing with the various ecological, biological and social as well as regulatory aspects for the deployment of genetically modified vectors in special context with the biosafety of humans, his associates, and the environment. Written by an array of specialists and experts in various subjects of genetically modified organisms, this book centrally addresses the (i) basic principles of the genetic manipulation of vectors and they are potential impact on human and the environment, (ii) ecological, biological, ethical, legal and social implications of the use of genetically modified vectors, (iii) identification of potential hazards; assessment and management of risks for human and environment; risk/benefit analysis, (iv) principles and practices for the assessment and management of biosecurity and biosafety in laboratories (and in the field), (v) guiding principles for creation and management of institutional or national biosafety review boards and ethics review committees, and (vi) development and application of a biosafety regulatory framework and its related legal principles at national levels for securing the development and use of vector control methods based on genetic modification strategies. This publication will be useful to researchers, scientists, and professionals engaged in academic and research institutions, government or non-government, as well as students in universities and medical colleges.

• Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences,Committee on Gene Drive Research in Non-Human Organisms: Recommendations for Responsible Conduct
• Publisher : National Academies Press
• Release Date : 2016-08-28
• Total pages : 231
• ISBN : 9780309437875
• File Size : 27,7 Mb
• Total Download : 397
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Download Gene Drives on the Horizon in PDF, Epub, and Kindle

Research on gene drive systems is rapidly advancing. Many proposed applications of gene drive research aim to solve environmental and public health challenges, including the reduction of poverty and the burden of vector-borne diseases, such as malaria and dengue, which disproportionately impact low and middle income countries. However, due to their intrinsic qualities of rapid spread and irreversibility, gene drive systems raise many questions with respect to their safety relative to public and environmental health. Because gene drive systems are designed to alter the environments we share in ways that will be hard to anticipate and impossible to completely roll back, questions about the ethics surrounding use of this research are complex and will require very careful exploration. Gene Drives on the Horizon outlines the state of knowledge relative to the science, ethics, public engagement, and risk assessment as they pertain to research directions of gene drive systems and governance of the research process. This report offers principles for responsible practices of gene drive research and related applications for use by investigators, their institutions, the research funders, and regulators.

• Author : W. Takken,T.W. Scott
• Publisher : Springer
• Release Date : 2003-08-31
• Total pages : 244
• ISBN : 9781402015847
• File Size : 9,5 Mb
• Total Download : 834
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Download Ecological Aspects for Application of Genetically Modified Mosquitoes in PDF, Epub, and Kindle

This book is the reflection of a workshop, held in June 2002. Experts on mosquito ecology met for the first time to discuss the current knowledge of mosquito ecology with respect to GM-insect technology. Emphasis of the workshop was on evaluating how human health and natural ecosystems, including target wild-mosquito populations, will respond to the invasion of GM vectors. This volume will stimulate discussion by clearly showing the importance of vector ecology for prevention of vector-borne diseases.

• Author : Norbert Becker,Dušan Petrić,Marija Zgomba,Clive Boase,Minoo B. Madon,Christine Dahl,Achim Kaiser
• Publisher : Springer Nature
• Release Date : 2020-09-30
• Total pages : 570
• ISBN : 9783030116231
• File Size : 14,9 Mb
• Total Download : 869
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Download Mosquitoes in PDF, Epub, and Kindle

“Mosquitoes – Identification, Ecology and Control” presents a wealth of information on the bionomics, systematics, ecology, research techniques and control of both nuisance and disease vector mosquitoes. It provides practical guidance and important information in an easily readable style, suitable for anyone involved with, or interested in mosquitoes and their management. In this new edition, 102 European species including the most important invasive species and more than 100 globally important vector and nuisance species are described. Most of them, including all European species, are presented in the fully illustrated identification keys, followed by a detailed description of the morphology, biology, distribution and medical importance of each species, including over 700 detailed drawings. “Mosquitoes – Identification, Ecology and Control” includes: · systematics and biology · medical significance · research techniques · morphological characteristics used for identification of larvae and adults · illustrated identification keys for larval and adult mosquito genera · morphology, ecology, and distribution of the species identified in the keys · biological, genetic, physical and chemical control of mosquitoes “Mosquitoes – Identification, Ecology and Control” is a valuable tool for vector ecologists, medical entomologists, students and all those involved with mosquito systematics, biology, ecology, and control world-wide. Society as a whole benefit from the implementation of carefully designed and sustainable programs for the management of mosquitoes, and the diseases they transmit. The third edition of this successful publication has been comprehensively updated and expanded, to provide the foundation of a more enlightened and informed approach to mosquito management.

• Author : Rebeca Carballar-Lejarazú
• Publisher : CRC Press
• Release Date : 2023-02-24
• Total pages : 277
• ISBN : 9781000626001
• File Size : 26,7 Mb
• Total Download : 892
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Download Mosquito Gene Drives and the Malaria Eradication Agenda in PDF, Epub, and Kindle

Malaria is one of most serious infectious diseases today and has afflicted humankind for thousands of years. A significant number of people still die from this mosquito-borne disease, despite the use of various malaria prevention and control methods over hundreds of years and more than a century of coordinated global control efforts using modern tools, together with research into and development of new strategies for prevention, diagnosis, and disease treatment. Genetic approaches that focus on the vector mosquitoes to prevent malaria parasite transmission have been considered for many decades. Genetic control strategies received a significant boost with the successful development of gene drive systems, genetic methods for rapidly spreading beneficial genes and phenotypes through mosquito populations. This book reviews some concepts of gene drive systems and describes pioneering applications to control mosquito populations and prevent parasite transmission.

• Author : Molly Sue Hartzog
• Publisher : Unknown
• Release Date : 2016
• Total pages : 140
• ISBN : OCLC:949015757
• File Size : 39,7 Mb
• Total Download : 811
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Download Inventing Mosquitoes in PDF, Epub, and Kindle

PDF book entitled Inventing Mosquitoes written by Molly Sue Hartzog and published by Unknown which was released on 2016 with total hardcover pages 140, the book become popular and critical acclaim.

• Author : Willem Takken,Constantianus J.M. Koenraadt
• Publisher : Wageningen Academic Publishers
• Release Date : 2012-12-11
• Total pages : 273
• ISBN : 9789086861880
• File Size : 16,7 Mb
• Total Download : 163
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Download Ecology of parasite-vector interactions in PDF, Epub, and Kindle

Vector-borne diseases continue to be one of the most important determinants affecting human and animal health. Large numbers of people suffer from diseases like malaria, dengue, filariasis and leishmaniasis, especially in the tropics. Whereas these diseases were eradicated from the temperate climate zones, in recent years the rising incidence of 'emerging' vector-borne diseases such as bluetongue, West Nile Virus, Lyme disease, tick-borne encephalitis and the recent outbreaks of chikungunya and dengue in southern Europe provide evidence that these diseases are resilient and can disperse to other regions and continents where before they were not present or relevant. Many tools for the management of vector-borne diseases are currently under pressure because of increasing drug and insecticide resistance, as well as the realization of biological variation of parasites and vectors and their ecosystems. At the same time, progress in our understanding of genetics, immunology, population biology and epidemiology allow for a better understanding of parasite-vector interactions. Here the state-of-the-art of these interactions is being reviewed, and means for using this information for advanced strategies of vector-borne disease control are proposed. 'Ecology of parasite-vector interactions' aims to provide a rapid overview of recent developments in the field of parasite-vector interactions and how this can be used for more effective and sustainable disease control.

• Author : Jorge Hendrichs,Rui Pereira,Marc J.B. Vreysen
• Publisher : CRC Press
• Release Date : 2021-02-01
• Total pages : 1028
• ISBN : 9781000393460
• File Size : 49,8 Mb
• Total Download : 133
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Download Area-wide Integrated Pest Management in PDF, Epub, and Kindle

Over 98% of sprayed insecticides and 95% of herbicides reach a destination other than their target species, including non-target species, air, water and soil. The extensive reliance on insecticide use reduces biodiversity, contributes to pollinator decline, destroys habitat, and threatens endangered species. This book offers a more effective application of the Integrated Pest Management (IPM) approach, on an area-wide (AW) or population-wide (AW-IPM) basis, which aims at the management of the total population of a pest, involving a coordinated effort over often larger areas. For major livestock pests, vectors of human diseases and pests of high-value crops with low pest tolerance, there are compelling economic reasons for participating in AW-IPM. This new textbook attempts to address various fundamental components of AW-IPM, e.g. the importance of relevant problem-solving research, the need for planning and essential baseline data collection, the significance of integrating adequate tools for appropriate control strategies, and the value of pilot trials, etc. With chapters authored by 184 experts from more than 31 countries, the book includes many technical advances in the areas of genetics, molecular biology, microbiology, resistance management, and social sciences that facilitate the planning and implementing of area-wide strategies. The book is essential reading for the academic and applied research community as well as national and regional government plant and human/animal health authorities with responsibility for protecting plant and human/animal health.

• Author : Colin R. Martin,Caroline Hollins-Martin,Victor R. Preedy,Rajkumar Rajendram
• Publisher : Academic Press
• Release Date : 2021-07-04
• Total pages : 554
• ISBN : 9780323903097
• File Size : 51,7 Mb
• Total Download : 479
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Download Zika Virus Impact, Diagnosis, Control, and Models in PDF, Epub, and Kindle

Zika Virus Impact, Diagnosis, Control, and Models: Volume Two: The Neuroscience of Zika examines diagnosis, vaccines, and potential therapy methods for Zika virus syndrome. The book also details the neuroscience of Guillain-Barré syndrome, its effects and neuromuscular rehabilitation. It is designed to help readers better understand detection, therapies for Zika virus, preventative vaccines, diagnosis and associated microcephaly. Chapters on models enable further research and understanding. This book has applicability for neuroscientists, neurologists, virologists and anyone working to better understand the evolution and pathogenesis of Zika virus-related conditions. Provides a broad range of topics related to the neuroscience of Zika, including its diagnosis, vaccines and therapy Contains chapter abstracts, key facts, a dictionary of terms and summary points to aid in understanding Discusses novel and non-pharmacological therapies, Guillain-Barré Syndrome and vaccine development Features chapters on rat, mouse, and guinea pig models of Zika and case reports of Zika co-infection with chikungunya, dengue-2 and Guillain-Barré Includes coverage of microcephaly and developmental delays and examines Zika outbreaks in Brazil, Honduras, Uganda, Jamaica and Mozambique

• Author : Peter W. Atkinson
• Publisher : Springer Science & Business Media
• Release Date : 2009-12-12
• Total pages : 260
• ISBN : 9789048124589
• File Size : 25,7 Mb
• Total Download : 415
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Download Vector Biology, Ecology and Control in PDF, Epub, and Kindle

Mir S. Mulla joined the faculty of the Entomology Department at the University of California, Riverside in 1956, only two years after the Riverside campus was established as an independent campus within the University of California system. Prior to his appointment, Mir received his B.S. from Cornell University and then moved to the University of California, Berkeley to pursue his graduate studies. His Ph.D. from Berkeley, awarded in 1955, completed his formal American education which was the purpose of his immigration from his native Kandahar in Afghanistan. In his over 50 years at Riverside, Mir has made an incalculable impact on vector biology both within the United States and in developing countries throughout the world. Within Southern California, Mir’s basic and applied research led to the rapid and sustainable control of mosquitoes and eye gnats in the Coachella Valley and so directly enabled this region to grow to the thriving, large community it is today. In 2006 his efforts in facilitating the development of the low desert of southern California were recognized through the dedication of the Mir S. Mulla Biological Control Facility by the Coachella Valley Mosquito and Vector Control District. His success has been so profound that it remains somewhat cryptic to the many who now reside in, visit, and enjoy, this region of California, oblivious to the insect problems that severely restrained development until Mir and his students ?rst applied their expertise many decades ago.

• Author : Anonim
• Publisher : World Health Organization
• Release Date : 2021-05-18
• Total pages : 196
• ISBN : 9789240025233
• File Size : 52,5 Mb
• Total Download : 930
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Download Guidance framework for testing genetically modified mosquitoes in PDF, Epub, and Kindle

PDF book entitled Guidance framework for testing genetically modified mosquitoes written by Anonim and published by World Health Organization which was released on 2021-05-18 with total hardcover pages 196, the book become popular and critical acclaim.

• Author : Henry Puerta-Guardo,Pablo Manrique-Saide
• Publisher : BoD – Books on Demand
• Release Date : 2023-01-04
• Total pages : 284
• ISBN : 9781803558523
• File Size : 51,6 Mb
• Total Download : 435
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Download Mosquito Research in PDF, Epub, and Kindle

With around 3,500 species identified so far, mosquitoes can be found in virtually every environment and continent around the globe. Blood-feeding biters (e.g., Anopheles, Culex, Aedes, Ochlerotatus, and Mansonia) are among the most influential vectors for harboring and transmitting mosquito-borne diseases (MBDs) such as Zika, Japanese encephalitis, West Nile fever, dengue fever, yellow fever, and malaria, among other diseases. More than 700 million human infections and 725,000 deaths occur every year. Mosquitoes are increasing in number worldwide, yet there are still no effective vaccines or prevention strategies. Thus, traditional vector control strategies remain the most common ways to combat these diseases. Despite this, MBDs linger as one of the major challenges for public health and vector control programs at both global and local levels. This book provides a comprehensive overview of MBDs and vector control strategies.

• Author : Irina Häcker,Antonios Alekos Augustinos,František Marec,Amanda Choo,Detlef Bartsch,Jaroslaw Krzywinski
• Publisher : Frontiers Media SA
• Release Date : 2023-06-01
• Total pages : 228
• ISBN : 9782832524817
• File Size : 53,6 Mb
• Total Download : 742
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Download Genetic Control of Insect Pest Species – Achievements, Challenges, and Perspectives in PDF, Epub, and Kindle

PDF book entitled Genetic Control of Insect Pest Species – Achievements, Challenges, and Perspectives written by Irina Häcker,Antonios Alekos Augustinos,František Marec,Amanda Choo,Detlef Bartsch,Jaroslaw Krzywinski and published by Frontiers Media SA which was released on 2023-06-01 with total hardcover pages 228, the book become popular and critical acclaim.

• Author : Jacques Derek Charlwood
• Publisher : CRC Press
• Release Date : 2019-07-31
• Total pages : 346
• ISBN : 9781000012187
• File Size : 40,9 Mb
• Total Download : 906
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Download The Ecology of Malaria Vectors in PDF, Epub, and Kindle

This practical book covers all aspects of the biology of malaria vectors, with notes on the vectors of dengue. It is the first work in this field to concentrate on mosquitoes, rather than covering all disease vectors. Authored by renowned field entomologist Jacques Derek Charlwood, it disseminates his vast experience working on mosquito biology, ecology and the evaluation of new vector control tools across five continents over the past 40 years. Covering all aspects from classification and systematics, population dynamics, vector control, to surveillance and sampling, epidemics, and a selection of case histories, the book also considers genetics and resistance, Aedes biology, and malaria and dengue models. It is designed to fill the gap between very specialized texts and undergraduate books on general disease vectors, and is ideal as a textbook for postgraduate courses in entomology and mosquito vectors of disease.

• Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Global Health,Forum on Microbial Threats
• Publisher : National Academies Press
• Release Date : 2016-10-21
• Total pages : 397
• ISBN : 9780309377591
• File Size : 51,8 Mb
• Total Download : 533
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Download Global Health Impacts of Vector-Borne Diseases in PDF, Epub, and Kindle

Pathogens transmitted among humans, animals, or plants by insects and arthropod vectors have been responsible for significant morbidity and mortality throughout recorded history. Such vector-borne diseases â€" including malaria, dengue, yellow fever, and plague â€" together accounted for more human disease and death in the 17th through early 20th centuries than all other causes combined. Over the past three decades, previously controlled vector-borne diseases have resurged or reemerged in new geographic locations, and several newly identified pathogens and vectors have triggered disease outbreaks in plants and animals, including humans. Domestic and international capabilities to detect, identify, and effectively respond to vector-borne diseases are limited. Few vaccines have been developed against vector-borne pathogens. At the same time, drug resistance has developed in vector-borne pathogens while their vectors are increasingly resistant to insecticide controls. Furthermore, the ranks of scientists trained to conduct research in key fields including medical entomology, vector ecology, and tropical medicine have dwindled, threatening prospects for addressing vector-borne diseases now and in the future. In June 2007, as these circumstances became alarmingly apparent, the Forum on Microbial Threats hosted a workshop to explore the dynamic relationships among host, pathogen(s), vector(s), and ecosystems that characterize vector-borne diseases. Revisiting this topic in September 2014, the Forum organized a workshop to examine trends and patterns in the incidence and prevalence of vector-borne diseases in an increasingly interconnected and ecologically disturbed world, as well as recent developments to meet these dynamic threats. Participants examined the emergence and global movement of vector-borne diseases, research priorities for understanding their biology and ecology, and global preparedness for and progress toward their prevention, control, and mitigation. This report summarizes the presentations and discussions from the workshop.

• Author : W. Takken,T.W. Scott
• Publisher : Springer Science & Business Media
• Release Date : 2003-07-31
• Total pages : 248
• ISBN : 1402015852
• File Size : 22,5 Mb
• Total Download : 562
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Download Ecological Aspects for Application of Genetically Modified Mosquitoes in PDF, Epub, and Kindle

This book is the reflection of a workshop, held in June 2002. Experts on mosquito ecology met for the first time to discuss the current knowledge of mosquito ecology with respect to GM-insect technology. Emphasis of the workshop was on evaluating how human health and natural ecosystems, including target wild-mosquito populations, will respond to the invasion of GM vectors. This volume will stimulate discussion by clearly showing the importance of vector ecology for prevention of vector-borne diseases.

• Author : Institute of Medicine,Board on Global Health,Forum on Microbial Threats
• Publisher : National Academies Press
• Release Date : 2008-03-18
• Total pages : 350
• ISBN : 9780309177702
• File Size : 53,9 Mb
• Total Download : 622
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Download Vector-Borne Diseases in PDF, Epub, and Kindle

Vector-borne infectious diseases, such as malaria, dengue fever, yellow fever, and plague, cause a significant fraction of the global infectious disease burden; indeed, nearly half of the world's population is infected with at least one type of vector-borne pathogen (CIESIN, 2007; WHO, 2004a). Vector-borne plant and animal diseases, including several newly recognized pathogens, reduce agricultural productivity and disrupt ecosystems throughout the world. These diseases profoundly restrict socioeconomic status and development in countries with the highest rates of infection, many of which are located in the tropics and subtropics. Although this workshop summary provides an account of the individual presentations, it also reflects an important aspect of the Forum philosophy. The workshop functions as a dialogue among representatives from different sectors and allows them to present their beliefs about which areas may merit further attention. These proceedings summarize only the statements of participants in the workshop and are not intended to be an exhaustive exploration of the subject matter or a representation of consensus evaluation. Vector-Borne Diseases : Understanding the Environmental, Human Health, and Ecological Connections, Workshop Summary (Forum on Microbial Threats) summarizes this workshop.

• Author : Arnim von Gleich,Winfried Schröder
• Publisher : Springer Nature
• Release Date : 2020-01-01
• Total pages : 256
• ISBN : 9783030389345
• File Size : 21,7 Mb
• Total Download : 693
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Download Gene Drives at Tipping Points in PDF, Epub, and Kindle

This open access book reports on a pilot project aiming at collecting information on the socio-ecological risks that could arise in the event of an uncontrolled spread of genetically engineered organisms into the environment. The researchers will, for instance, be taking a closer look at genetically engineered oilseed rape, genetically engineered olive flies as well as plants and animals with so-called gene drives. The book mainly adresses researchers.