Fluorine

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Fluorine

Fluorine
  • Author : Alain Tressaud
  • Publisher : Academic Press
  • Release Date : 2018-10-06
  • Total pages : 271
  • ISBN : 9780128129913
  • File Size : 25,8 Mb
  • Total Download : 715
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Fluorine: A Paradoxical Element, Volume Five, deals with the link between fluorine, humanity and the environment. It is divided into three main sections, including i) The history and developmental stages of fluorinated products, ii) Awareness of its importance in our environment, and iii) Recent contributions of fluoride products in medicine, pharmacy and our daily lives. Made engaging through interesting figures and accessible language, and written by a leading expert, Professor Tressaud, the book supports the work of scientists working in materials, toxicology and environmental science. It complements the author’s edited series, Progress in Fluorine Science, covering recent advances. Describes background and contextual information regarding the history, development of understanding, and applications of this important element Explores the impacts of fluorine, both positive and negative, in the environment and biological systems Includes applied, real-world information from agencies, such as CNRS, NASA, HWS and DOH

Graphite Fluorides & Carbon Fluoride Compounds

Graphite Fluorides & Carbon Fluoride Compounds
  • Author : Tsuyoshi Nakajima,Nobuatsu Watanabe
  • Publisher : CRC PressI Llc
  • Release Date : 1991
  • Total pages : 192
  • ISBN : UCAL:B4477581
  • File Size : 19,7 Mb
  • Total Download : 276
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PDF book entitled Graphite Fluorides & Carbon Fluoride Compounds written by Tsuyoshi Nakajima,Nobuatsu Watanabe and published by CRC PressI Llc which was released on 1991 with total hardcover pages 192, the book become popular and critical acclaim.

Guide to Fluorine NMR for Organic Chemists

Guide to Fluorine NMR for Organic Chemists
  • Author : W. R. Dolbier
  • Publisher : John Wiley & Sons
  • Release Date : 2009-05-20
  • Total pages : 272
  • ISBN : 9780470483398
  • File Size : 17,9 Mb
  • Total Download : 706
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Download Guide to Fluorine NMR for Organic Chemists in PDF, Epub, and Kindle

AN UNPARALLELED ONE-STOP GUIDE TO FLUORINE NMR Guide to Fluorine NMR for Organic Chemists provides a unique single source on both fluorine NMR and the impact of fluorine substituents on proton and carbon NMR spectra. Helping working chemists overcome the challenges associated with the synthetic methodologies of fluorinated compounds, this guide enables the effective use of these increasingly popular spectroscopic techniques to accurately characterize compounds that contain fluorine. Following a thorough introduction of fluorinated compounds, chapters in the text cover: An overview of fluorine NMR The single fluorine substituent The CF2 group The trifluoromethyl group More heavily fluorinated compounds Compounds and substituents with fluorine directly bound to heteroatoms With unparalleled depth and completeness, the coverage ranges from those compounds containing only a few fluorinated substituents, typically employed in pharmaceutical and agricultural applications, to more heavily fluorinated compounds. Featuring NMR data for more than 1,000 specific compunds and including more than 100 exemplary spectra, Guide to Fluorine NMR for Organic Chemists gives the working chemist and advanced student an essential tool for understanding cutting-edge NMR techniques and interpreting the resulting spectroscopic data.

Fluorine Chemistry

Fluorine Chemistry
  • Author : J.H. Simons
  • Publisher : Elsevier
  • Release Date : 2012-12-02
  • Total pages : 804
  • ISBN : 9780323142458
  • File Size : 48,9 Mb
  • Total Download : 669
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Fluorine Chemistry, Volume IV provides an extensive survey and discussion on the physiological properties of fluoride ion and substances capable of producing it in aqueous solution. This book elaborates the detrimental effects of excessive fluoride ingestion, through the beneficial effects of optimal amounts, to recognized detrimental effects, such as dental caries accompanied by suboptimal fluoride intake. Fluoride metabolism is discussed in detail, including the capacity for storage of fluoride by the bones and rates of excretion of fluoride from the body. This text also covers the relation of fluoride ion to the health of teeth and bones. This publication is a good source for chemists and clinicians intending to acquire knowledge of the biological effects of fluoride.

Fluorine

Fluorine
  • Author : Victor R Preedy
  • Publisher : Royal Society of Chemistry
  • Release Date : 2015-04-17
  • Total pages : 360
  • ISBN : 9781782624929
  • File Size : 33,8 Mb
  • Total Download : 417
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Fluorine is best known for its role in the prevention of cavities and in improving oral and bone health however equally there are millions of people around the world suffering from dental fluorosis due to chronic exposure to high levels of fluoride in drinking water. This volume, written by leading researchers in this area, examines the positives and negatives of fluorine and its effects on humans for example fluoride-induced oxidative stress in the liver, effects of fluoride on insulin and preventing fluoride toxicity. Extremely useful for underpinning cross-disciplinary fluorine research, this book provides a fascinating insight for those with an interest in the health and nutritional sciences.

Fluorine Chemistry Research Advances

Fluorine Chemistry Research Advances
  • Author : Ira V. Gardiner
  • Publisher : Nova Publishers
  • Release Date : 2007
  • Total pages : 322
  • ISBN : 1600217303
  • File Size : 39,5 Mb
  • Total Download : 900
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Fluorine continues to intrigue chemists who overcome the challenge of handling this remarkable halogen and work to develop varied methods for synthesising fluorine compounds. The unique properties of these materials, ranging from inert perfluorocarbons and fluoropolymers to a multitude of other fascinating fluorinated compounds, firmly established their place amidst the technological achievements of the 20th Century. Fluorine substitution in biologically active compounds has become particularly significant in recent years. This book presents new and significant research in this field.

Modern Synthesis Processes and Reactivity of Fluorinated Compounds

Modern Synthesis Processes and Reactivity of Fluorinated Compounds
  • Author : Henri Groult,Frederic Leroux,Alain Tressaud
  • Publisher : Elsevier
  • Release Date : 2016-11-04
  • Total pages : 760
  • ISBN : 9780128037904
  • File Size : 20,5 Mb
  • Total Download : 412
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Modern Synthesis Processes and Reactivity of Fluorinated Compounds focuses on the exceptional character of fluorine and fluorinated compounds. This comprehensive work explores examples taken from all classes of fluorine chemistry and illustrates the extreme reactivity of fluorinating media and the peculiar synthesis routes to fluorinated materials. The book provides advanced and updated information on the latest synthesis routes to fluorocompounds and the involved reaction mechanisms. Special attention is given to the unique reactivity of fluorine and fluorinated media, along with the correlation of those properties to valuable applications of fluorinated compounds. Contains quality content edited, and contributed, by leading scholars in the field Presents applied guidance on the preparation of original fluorinated compounds, potentially transferable from the lab scale to industrial applications Provides practical synthesis information for a wide audience interested in fluorine compounds in many branches of chemistry, materials science, and physics

Experimental Methods in Organic Fluorine Chemistry

Experimental Methods in Organic Fluorine Chemistry
  • Author : Tomoya Kitazume
  • Publisher : Routledge
  • Release Date : 2019-06-14
  • Total pages : 272
  • ISBN : 9781351449236
  • File Size : 31,6 Mb
  • Total Download : 995
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In the fields of biologically active materials and functional materials, fluorinated organic materials are becoming a focus of significant interest. Over the past decade synthetic methodologies and reagents in fluorine chemistry have been developed, especially stereocontrolled synthetic methods, enzymatic resolution to synthesize enantiomers, fluoromethylated reagents, and fluorination reagents. These methods have contributed to the opening of new pathways for fluorinated materials. However, few fluorinated materials have been put to commercial use. Furthermore, there remain problems to be solved, such as the handling of the materials, availability of reagents and selectivity (stereo-, regio-, and/or chemoselectivity). Research chemists, technical engineers, and graduate students in all branches of chemistry, pharmaceutics, and material science interested in fluorinated materials need to know detailed experimental procedures of how to synthesize the target fluorinated materials. This volume summarizes the chemical and microbial methods for obtaining functionalized fluorinated materials for use as building blocks; detailed experimental methods (reaction conditions, solvent, temperature, handling techniques, etc.); and the stereoview (possible absolute configuration) of the structures with spectral data. Mono-, di-, tri-, and polyfluorinated materials derived from fluorinating agents, fluoromethylated reagents and building blocks are summarized. A chemical name index, molecular formula index, and reagent index are also included. The publication of this monograph will provide access to the enormous possibilities in fluorine chemistry, biological material chemistry, and functionalized material chemistry.

Fluorine in Heterocyclic Chemistry Volume 2

Fluorine in Heterocyclic Chemistry Volume 2
  • Author : Valentine Nenajdenko
  • Publisher : Springer
  • Release Date : 2014-07-08
  • Total pages : 760
  • ISBN : 9783319044354
  • File Size : 22,7 Mb
  • Total Download : 553
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This two-volume work combines comprehensive information on the chemistry of the fluorinated heterocycles. The material has been divided such that the first volume is dedicated to 5-membered fluorinated heterocycles and macrocycles, while the second volume combines data connected with the chemistry of fluorine containing 6-membered heterocycles. Both volumes will be of interest to synthetic organic chemists in general, and particularly for those colleagues working in the fields of heterocyclic-compound chemistry, materials chemistry, medicinal chemistry, and fluorine chemistry. All information is presented and classified clearly to be effective source for broad auditory of chemists. It will be interesting for scientists working in the field of inorganic and coordination chemistry. Fluorinated heterocycles are becoming increasingly important in many areas including the pharmaceutical industry, materials science and agriculture. The presence of fluorine can result in substantial functional changes in the biological as well as physicochemical properties of organic compounds. Incorporation of fluorine into drug molecules can greatly affect their physicochemical properties, such as bond strength, lipophilicity, bioavailability, conformation, electrostatic potential, dipole moment, pKa etc. as well as pharmacokinetic properties, such as tissue distribution, rate of metabolism and pharmacological properties, such as pharmacodynamics and toxicology.

Fluorine in Stomatology and Hygiene

Fluorine in Stomatology and Hygiene
  • Author : Rafail Davidovich Gabovich,G. D. Ovrut{u0361}skiĭ
  • Publisher : Unknown
  • Release Date : 1977
  • Total pages : 1044
  • ISBN : UOM:39015000288426
  • File Size : 16,8 Mb
  • Total Download : 824
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PDF book entitled Fluorine in Stomatology and Hygiene written by Rafail Davidovich Gabovich,G. D. Ovrut{u0361}skiĭ and published by Unknown which was released on 1977 with total hardcover pages 1044, the book become popular and critical acclaim.

Fluorine, Its Compounds, and Air Pollution

Fluorine, Its Compounds, and Air Pollution
  • Author : Air Pollution Technical Information Center
  • Publisher : Unknown
  • Release Date : 1976
  • Total pages : 618
  • ISBN : UCAL:B4193541
  • File Size : 16,8 Mb
  • Total Download : 233
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PDF book entitled Fluorine, Its Compounds, and Air Pollution written by Air Pollution Technical Information Center and published by Unknown which was released on 1976 with total hardcover pages 618, the book become popular and critical acclaim.

Fluorine-Carbon and Fluoride-Carbon Materials

Fluorine-Carbon and Fluoride-Carbon Materials
  • Author : Tsuyoshi Nakajima
  • Publisher : CRC Press
  • Release Date : 1994-12-20
  • Total pages : 416
  • ISBN : 9781482293562
  • File Size : 29,6 Mb
  • Total Download : 179
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"This outstanding reference presents the latest scientific findings concerning the synthesis, structure, thermodynamics, and physical and chemical properties of fluorine- and fluoride-carbon compounds elucidating their practical applications in lithium batteries, superhydrophobic composites, and the electrolytic production of elemental fluorine."

Guide to Fluorine NMR for Organic Chemists

Guide to Fluorine NMR for Organic Chemists
  • Author : William R. Dolbier, Jr.
  • Publisher : John Wiley & Sons
  • Release Date : 2016-08-22
  • Total pages : 368
  • ISBN : 9781118831113
  • File Size : 42,5 Mb
  • Total Download : 601
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Following its well-received predecessor, this book offers an essential guide to chemists for understanding fluorine in spectroscopy. With over 1000 compounds and 100 spectra, the second edition adds new data – featuring fluorine effects on nitrogen NMR, chemical shifts, and coupling constants. • Explains how to successfully incorporate fluorine into target molecules and utilize fluorine substituents to structurally characterize organic compounds • Includes new data on nitrogen NMR, focusing on N-15, to portray the influence of fluorine upon nitrogen NMR chemical shifts and coupling constants • Expands on each chapter from the first edition with additional data and updated discussion from recent findings • "The flawless ordering of material covered in this stand-alone volume is such that information can be found very easily." – Angewandte Chemie review of the first edition, 2010

Fluorine in Pharmaceutical and Medicinal Chemistry

Fluorine in Pharmaceutical and Medicinal Chemistry
  • Author : Véronique Gouverneur,Klaus Müller
  • Publisher : World Scientific
  • Release Date : 2012
  • Total pages : 571
  • ISBN : 9781848166349
  • File Size : 38,8 Mb
  • Total Download : 660
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Fluorine chemistry is an expanding area of research that is attracting international interest, due to the impact of fluorine in drug discovery and in clinical and molecular imaging (e.g. PET, MRI). Many researchers and academics are entering this area of research, while scientists in industrial and clinical environments are also indirectly exposed to fluorine chemistry through the use of fluorinated compounds for imaging. This book provides an overview of the impact that fluorine has made in the life sciences. In the first section, the emphasis is on how fluorine substitution of amino acids, peptides, nucleobases and carbohydrates can provide invaluable information at a molecular level. The following chapters provide answers to the key questions posed on the importance of fluorine in drug discovery and clinical applications. For examples, the reader will discover how fluorine has found its place as a key element improving drug efficacy, with reference to some of the best-selling drugs on the market. Finally, a thorough review on the design, synthesis and use of 18F-radiotracers for positron emission tomography is provided, and this is complemented with a discussion on how 19F NMR has advanced molecular and clinical imaging.

Fluorine in Life Sciences: Pharmaceuticals, Medicinal Diagnostics, and Agrochemicals

Fluorine in Life Sciences: Pharmaceuticals, Medicinal Diagnostics, and Agrochemicals
  • Author : Gunter Haufe,Frederic Leroux
  • Publisher : Academic Press
  • Release Date : 2018-09-19
  • Total pages : 686
  • ISBN : 9780128127346
  • File Size : 53,8 Mb
  • Total Download : 151
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Fluorine in Life Sciences: Pharmaceuticals, Medicinal Diagnostics and Agrochemicals, volume four in Alain Tressaud’s Progress in Fluorine Science series, presents a critical, multidisciplinary overview of the contributions of fluorinated products to solve important global issues in various life science fields, particularly in medicinal chemistry, molecular imaging techniques and agriculture. Edited by recognized experts, this book provides unique coverage of the wide-ranging uses and implications of fluorine and fluorinated compounds. Topics include medicinal monitoring and diagnosis, 19F MRI in medicine and in vivo cell tracking, 18F-labeled radiopharmaceuticals, brain imaging and neurology, risk assessment of reactive metabolites in drug discovery, and more. Edited by Alain Tressaud, past Chair and founder of the CNRS French Fluorine Network, each book in the collection also includes the work of highly-respected volume editors and contributors from both academia and industry who bring valuable and varied content to this active field. Covers a wide range of topics - from organic and physical chemistry, to pharmaceuticals, agrochemicals and medical diagnostics Describes major modern syntheses and unique reaction mechanisms yielding fluorine compounds in these diverse life science settings Features contributions from a wealth of global experts Acts as the fourth volume in Alain Tressaud’s Progress in Fluorine Science

Fluorine in Organic Chemistry

Fluorine in Organic Chemistry
  • Author : Richard D. Chambers
  • Publisher : CRC Press
  • Release Date : 2004
  • Total pages : 426
  • ISBN : 0849317908
  • File Size : 42,6 Mb
  • Total Download : 750
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The introduction of carbon-fluorine bonds into organic compounds can profoundly influence their chemical and physical properties when compared to their non-fluorine-containing analogues, leading to a range of man-made materials with highly desirable properties. These molecules are of interest across the wide spectrum of industrial and academic organic chemistry, from pharmaceuticals, through fine and specialty chemicals to polymers. From Prozac to Teflon, many of the most important products of the chemical and life-science industries rely on organic fluorine chemistry for their useful properties. This book covers both the preparative methodologies and chemical properties of partially and highly fluorinated organic systems.

Fluorine and Health

Fluorine and Health
  • Author : Alain Tressaud,Gunter Haufe
  • Publisher : Elsevier
  • Release Date : 2008-06-06
  • Total pages : 816
  • ISBN : 0080558119
  • File Size : 22,5 Mb
  • Total Download : 656
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Fluorine and Health presents a critical multidisciplinary overview on the contribution of fluorinated compounds to resolve the important global issue of medicinal monitoring and health care. The involved subjects are organized in three thematic parts devoted to Molecular Imaging, Biomedical Materials and Pharmaceuticals. Initially the key-position of partially fluorinated low molecular weight compounds labelled either with the natural 19F-isotope for Magnetic Resonance Imaging (MRI) or labelled with the radioactive [18F]-isotope for Positron Emission Tomography (PET) is highlighted. Both non-invasive methods belong to the most challenging in vivo imaging techniques in oncology, neurology and in cardiology for the diagnosis of diseases having the highest mortality in the industrialized countries. The manifold facets of fluorinated biomaterials range from inorganic ceramics to perfluorinated organic molecules. Liquid perfluorocarbons are suitable for oxygen transport and as potential respiratory gas carriers, while fluorinated polymers are connected to the pathology of blood vessels. Another important issue concerns the application of highly fluorinated liquids in ophthalmology. Moreover, fluorine is an essential trace element in bone mineral, dentine and tooth enamel and is applied for the prophylaxis and treatment of dental caries. The various origins of human exposure to fluoride species is detailed to promote a better understanding of the effect of fluoride species on living organisms. Medicinally relevant fluorinated molecules and their interactions with native proteins are the main focus of the third part. New molecules fluorinated in strategic position are crucial for the development of pharmaceuticals with desired action and optimal pharmacological profile. Among the hundreds of marketed active drug components there are more than 150 fluorinated compounds. The chapters will illustrate how the presence of fluorine atoms alters properties of bioactive compounds at various biochemical steps, and possibly facilitate its emergence as pharmaceuticals. Finally the synthetic potential of a fluorinase, the first C-F bond forming enzyme, is summarized. - New approach of topics involving chemistry, biology and medicinal techniques - Transdisciplinar papers on fluoride products - Importance of fluoride products in health - Updated data on specific topics

Efficient Preparations of Fluorine Compounds

Efficient Preparations of Fluorine Compounds
  • Author : Herbert W. Roesky
  • Publisher : John Wiley & Sons
  • Release Date : 2012-10-11
  • Total pages : 482
  • ISBN : 9781118409442
  • File Size : 34,6 Mb
  • Total Download : 437
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The definitive guide to creating fluorine-based compounds—and the materials of tomorrow Discovered as an element by the French chemist Henri Moissan in 1886, through electrolysis of potassium fluoride in anhydrous hydrogen fluoride—"le fluor," or fluorine, began its chemical history as a substance both elusive and dangerous. With a slight pale yellow hue, fluorine is at room temperature a poisonous diatomic gas. Resembling a spirit from a chemical netherworld, fluorine is highly reactive, difficult to handle, yet very versatile as a reagent—with the power to form compounds with almost any other element. Comprising 20% of pharmaceutical products and 30% of agrochemical compounds, as well as playing a key role in electric cars, electronic devices, and space technology, compounds containing fluorine have grown in importance across the globe. Learning how to safely handle fluorine in the preparation of innovative new materials—with valuable new properties—is of critical importance to chemists today. Bringing together the research and methods of leading scientists in the fluorine field, Efficient Preparations of Fluorine Compounds is the definitive manual to creating, and understanding the reaction mechanisms integral to a wide variety of fluorine compounds. With sixty-eight contributed chapters, the book's extensive coverage includes: Preparation of Elemental Fluorine Synthesis Methods for Exotic Inorganic Fluorides with Varied Applications Introduction of Fluorine into Compounds via Electrophilic and Nucleophilic Reactions Direct Fluorination of Organic Compounds with Elemental Fluorine Efficient Preparations of Bioorganic Fluorine Compounds Asymmetric Fluorocyclization Reactions Preparations of Rare Earth Fluorosulfides and Oxyfluorosulfides The book offers methods and results that can be reproduced by students involved in advanced studies, as well as practicing chemists, pharmaceutical scientists, biologists, and environmental researchers. The only chemical resource of its kind, Efficient Preparations of Fluorine Compounds—from its first experiment to its last—is a unique window into the centuries old science of fluorine and the limitless universe of fluorine-based compounds.

Publications

Publications
  • Author : University of Chicago Clinics. Walter G. Zoller Memorial Dental Clinic
  • Publisher : Unknown
  • Release Date : 1944
  • Total pages : 229
  • ISBN : CHI:79871944
  • File Size : 44,8 Mb
  • Total Download : 581
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PDF book entitled Publications written by University of Chicago Clinics. Walter G. Zoller Memorial Dental Clinic and published by Unknown which was released on 1944 with total hardcover pages 229, the book become popular and critical acclaim.

Organic and Inorganic Fluorine Chemistry

Organic and Inorganic Fluorine Chemistry
  • Author : Axel Haupt
  • Publisher : Walter de Gruyter GmbH & Co KG
  • Release Date : 2021-03-22
  • Total pages : 642
  • ISBN : 9783110659504
  • File Size : 42,5 Mb
  • Total Download : 996
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This textbook provides a comprehensive overview of synthesis protocols for organic and inorganic fluorinated compounds. Electrochemical fluorination, nucleophilic, radical and electrophilic addition is discussed. Applications of organofluorine compounds, main group fluorides and metal fluorides in pharmaceuticals, electronic devices and medical diagnostics is covered. Each chapter will be followed by exercises covering the topics.

Fluorinated Hydrocarbons—Advances in Research and Application: 2013 Edition

Fluorinated Hydrocarbons—Advances in Research and Application: 2013 Edition
  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release Date : 2013-06-21
  • Total pages : 357
  • ISBN : 9781481675703
  • File Size : 9,9 Mb
  • Total Download : 614
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Fluorinated Hydrocarbons—Advances in Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Chlorofluorocarbons. The editors have built Fluorinated Hydrocarbons—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Chlorofluorocarbons in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Fluorinated Hydrocarbons—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.