Evolving Landscape Of Molecular Diagnostics Applications And Techniques

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Evolving Landscape of Molecular Diagnostics

Evolving Landscape of Molecular Diagnostics
  • Author : Mrutyunjay Suar,Prashanth Singh,Namrata Misra
  • Publisher : Elsevier
  • Release Date : 2022-09-15
  • Total pages : 300
  • ISBN : 0323993168
  • File Size : 24,5 Mb
  • Total Download : 424
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Evolving Landscape of Molecular Diagnostics: Applications and Techniques presents cutting-edge reviews on current and emerging technologies in the diagnosis of microbial infections. The book discusses the fundamentals of Molecular Diagnostics for bacteria, fungi, viruses and a variety of state-of-the-art diagnostics tools and techniques for obtaining qualitative and quantitative results. It includes topics such as Next generation sequencing and application of "OMICS" for early disease diagnosis. Sections cover the entire spectrum of emerging diagnostic tools and techniques, as well as the principles, pros and cons of each method and applications for diagnosis of infectious disease in plants, humans and veterinary. This is a resource for both researchers and students working in clinical microbiology, infectious biology, applied life sciences and scientists working in the clinical diagnostic industry. Provides a wide range of diagnostics tools and technologies in the field of infectious biology Presents discussions on emerging technologies for early disease diagnosis and novel diagnostics techniques for detection of COVID, Urea Breath Tests for Detection of Helicobacter pylori, Loop-Mediated Isothermal Amplification as Point-of-Care Diagnosis, Molecular imaging, Lab-on-a-chip Technologies, and several others Analyzes literature reviews, underpinning methodologies, and opportunities and limitations Includes case studies and examples that highlight applications using the underpinning techniques

Molecular Microbiology

Molecular Microbiology
  • Author : David H. Persing,Fred C. Tenover,Randall T. Hayden,Margareta Ieven,Melissa B. Miller,Frederick S. Nolte,Yi-Wei Tang,Alex van Belkum
  • Publisher : John Wiley & Sons
  • Release Date : 2020-07-24
  • Total pages : 835
  • ISBN : 9781555819071
  • File Size : 45,6 Mb
  • Total Download : 484
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Presenting the latest molecular diagnostic techniques in one comprehensive volume The molecular diagnostics landscape has changed dramatically since the last edition of Molecular Microbiology: Diagnostic Principles and Practice in 2011. With the spread of molecular testing and the development of new technologies and their opportunities, laboratory professionals and physicians more than ever need a resource to help them navigate this rapidly evolving field. Editors David Persing and Fred Tenover have brought together a team of experienced researchers and diagnosticians to update this third edition comprehensively, to present the latest developments in molecular diagnostics in the support of clinical care and of basic and clinical research, including next-generation sequencing and whole-genome analysis. These updates are provided in an easy-to-read format and supported by a broad range of practical advice, such as determining the appropriate type and quantity of a specimen, releasing and concentrating the targets, and eliminating inhibitors. Molecular Microbiology: Diagnostic Principles and Practice Presents the latest basic scientific theory underlying molecular diagnostics Offers tested and proven applications of molecular diagnostics for the diagnosis of infectious diseases, including point-of-care testing Illustrates and summarizes key concepts and techniques with detailed figures and tables Discusses emerging technologies, including the use of molecular typing methods for real-time tracking of infectious outbreaks and antibiotic resistance Advises on the latest quality control and quality assurance measures Explores the increasing opportunities and capabilities of information technology Molecular Microbiology: Diagnostic Principles and Practice is a textbook for molecular diagnostics courses that can also be used by anyone involved with diagnostic test selection and interpretation. It is also a useful reference for laboratories and as a continuing education resource for physicians.

Principles and Applications of Molecular Diagnostics

Principles and Applications of Molecular Diagnostics
  • Author : Nader Rifai,A. Rita Horvath,Carl T. Wittwer,Jason Park
  • Publisher : Elsevier
  • Release Date : 2018-06-13
  • Total pages : 422
  • ISBN : 9780128160626
  • File Size : 55,6 Mb
  • Total Download : 982
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Principles and Applications of Molecular Diagnostics serves as a comprehensive guide for clinical laboratory professionals applying molecular technology to clinical diagnosis. The first half of the book covers principles and analytical concepts in molecular diagnostics such as genomes and variants, nucleic acids isolation and amplification methods, and measurement techniques, circulating tumor cells, and plasma DNA; the second half presents clinical applications of molecular diagnostics in genetic disease, infectious disease, hematopoietic malignancies, solid tumors, prenatal diagnosis, pharmacogenetics, and identity testing. A thorough yet succinct guide to using molecular testing technology, Principles and Applications of Molecular Diagnostics is an essential resource for laboratory professionals, biologists, chemists, pharmaceutical and biotech researchers, and manufacturers of molecular diagnostics kits and instruments. Explains the principles and tools of molecular biology Describes standard and state-of-the-art molecular techniques for obtaining qualitative and quantitative results Provides a detailed description of current molecular applications used to solve diagnostics tasks

Molecular Diagnostics in Cytopathology

Molecular Diagnostics in Cytopathology
  • Author : Sinchita Roy-Chowdhuri,Paul A. VanderLaan,John M. Stewart,Gilda da Cunha Santos
  • Publisher : Springer
  • Release Date : 2018-11-21
  • Total pages : 534
  • ISBN : 9783319973975
  • File Size : 50,5 Mb
  • Total Download : 797
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Molecular diagnostics are increasingly used to help guide targeted therapy in solid organ tumors and hematologic malignancies. A large proportion of molecular testing is performed on limited-volume samples obtained via minimally invasive techniques, such as fine needle aspiration. Increasingly, cytopathologists play an essential role in this process, both in the triage of specimens during rapid on-site evaluation and in the evaluation of archival samples to determine suitability for ancillary testing. Therefore, it is imperative that practicing cytopathologists stay abreast of up-to-date diagnostic, prognostic, and predictive ancillary tests that can be used on limited cytologic material. This is a challenge since the landscape of known genomic alterations is constantly evolving and the subsequent set of testing options is ever expanding. The proposed text will provide a user-friendly quick-reference handbook to serve as a useful resource for practicing pathologists and laboratory personnel dealing with, and interested in, this evolving field of molecular cytopathology. Essential components to be presented include: 1) pre-analytic factors that affect sample selection and evaluation; 2) specimen preparation to maximize confidence in results; 3) interpretation of results; 4) potential limitations; and 5) workflow algorithms. In addition, specific disease specific molecular testing details will be outlined to provide the reader with resources for quick reference. All chapters will be written by experts in their fields and will include the most up-to-date scientific and clinical information. Molecular Diagnostics in Cytopathology will be of value to Cytopathologists, Cytotechnologists, Cytotechnology students, Cytopathology fellows, Surgical pathologists, Pathology residents and fellows, Molecular Pathologists, Molecular pathology fellows, Molecular technologists, as well as Translational researchers with an interest in molecular cytopathology.

Molecular Pathology of Breast Cancer

Molecular Pathology of Breast Cancer
  • Author : Sunil Badve,Yesim Gökmen-Polar
  • Publisher : Springer
  • Release Date : 2016-11-26
  • Total pages : 428
  • ISBN : 9783319417615
  • File Size : 55,6 Mb
  • Total Download : 522
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The complex landscape of breast cancer requires distinct strategies for the management of various molecular subtypes of this disease. Rapid advances in the field of molecular biology have been bewildering for those involved in its study and management. “Molecular Pathology of Breast Cancer” aims to close this knowledge gap by discussing comprehensively the evolution, biological basis and clinical applications with a focus on the “what, when, and how” of the most significant molecular markers known to date. These markers are evaluated in the context of genomic, transcriptomic and proteomic profiles, which is integral to the practice of precision medicine. The application of next generation sequencing (NGS) has provided new insights in the regulation of genomic and transcriptomic structure and function. Alterations in DNA such as mutations and single nucleotide polymorphisms (SNPs) have been correlated with outcomes and provide for novel therapeutic approaches. These NGS analyses have also revealed the extensive contributions of epigenetic mechanisms such as histone modifications, non-coding RNA and alternative splicing. All of these changes together contribute to alterations in proteome. Newer assays that allow greater stability and analytical consistency are emerging. These alterations in tumor profiles can be also now detected by imaging techniques. The heterogeneity of both tumor and tumor microenvironment, an inevitable reality, is discussed in detail with particular focus on cancer stem cells and immune signaling. A chapter is dedicated to the emerging technology of “liquid biopsy”, which opens a novel approach for “continuous” monitoring of cancer that might be superior to conventional diagnostics, “Molecular Pathology of Breast Cancer” provides a quick and easy, not to mention essential, tour for clinicians, pathologists and scientists who are seeking to understand the integration of molecular biology into the diagnosis, prognosis and management of breast cancer.

Foundations of Genetic Programming

Foundations of Genetic Programming
  • Author : William B. Langdon,Riccardo Poli
  • Publisher : Springer Science & Business Media
  • Release Date : 2002-02-14
  • Total pages : 68
  • ISBN : 3540424512
  • File Size : 54,5 Mb
  • Total Download : 923
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Genetic programming (GP), one of the most advanced forms of evolutionary computation, has been highly successful as a technique for getting computers to automatically solve problems without having to tell them explicitly how. Since its inceptions more than ten years ago, GP has been used to solve practical problems in a variety of application fields. Along with this ad-hoc engineering approaches interest increased in how and why GP works. This book provides a coherent consolidation of recent work on the theoretical foundations of GP. A concise introduction to GP and genetic algorithms (GA) is followed by a discussion of fitness landscapes and other theoretical approaches to natural and artificial evolution. Having surveyed early approaches to GP theory it presents new exact schema analysis, showing that it applies to GP as well as to the simpler GAs. New results on the potentially infinite number of possible programs are followed by two chapters applying these new techniques.

The Evolving Landscape

The Evolving Landscape
  • Author : Homer Aschmann
  • Publisher : Unknown
  • Release Date : 1997
  • Total pages : 464
  • ISBN : UCSC:32106014522541
  • File Size : 12,5 Mb
  • Total Download : 505
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"Aschmann was a keen and impassioned observer of the impacts of modern societies on the natural world." -- Karl Butzer, Dickson Centennial Professor of Liberal Arts, University of Kansas, Austin In The Evolving Landscape Martin J. Pasqualetti brings together for the first time the collected writings of one of twentieth-century America's master geographers, Homer Aschmann. Combining encyclopedic knowledge with unquenchable curiosity, Aschmann radiates an obvious affection for being outdoors as he guides us across landscapes to discern the interplay of climate, history, topography, soils, and vegetation. In settings as diverse as Los Angeles, Baja California, Arizona, Paraguay, Chile, Colombia, and the Canary Islands, Aschmann demonstrates the contribution a geographer can make in explaining environmental change. "Aschmann was a master of the geographical art." -- William M. Denevan, Carl O. Sauer Professor Emeritus, University of Wisconsin, Madison "Serious students of the landscape will be startled by how relevant and contemporary these seminal essays remain." -- Richard Francaviglia, Director, Center for Greater Southwestern Studies and the History of Cartography, University of Texas at Arlington "Aschmann's broad perspectives are a fast disappearing form of Geography which we lose at our science's peril." -- Carl L. Johannessen, Professor of Geography, University of Oregon

Molecular Diagnostics

Molecular Diagnostics
  • Author : George P. Patrinos,Wilhelm Ansorge,Phillip B. Danielson
  • Publisher : Academic Press
  • Release Date : 2016-10-27
  • Total pages : 520
  • ISBN : 9780128029886
  • File Size : 18,9 Mb
  • Total Download : 372
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Molecular Diagnostics, Third Edition, focuses on the technologies and applications that professionals need to work in, develop, and manage a clinical diagnostic laboratory. Each chapter contains an expert introduction to each subject that is next to technical details and many applications for molecular genetic testing that can be found in comprehensive reference lists at the end of each chapter. Contents are divided into three parts, technologies, application of those technologies, and related issues. The first part is dedicated to the battery of the most widely used molecular pathology techniques. New chapters have been added, including the various new technologies involved in next-generation sequencing (mutation detection, gene expression, etc.), mass spectrometry, and protein-specific methodologies. All revised chapters have been completely updated, to include not only technology innovations, but also novel diagnostic applications. As with previous editions, each of the chapters in this section includes a brief description of the technique followed by examples from the area of expertise from the selected contributor. The second part of the book attempts to integrate previously analyzed technologies into the different aspects of molecular diagnostics, such as identification of genetically modified organisms, stem cells, pharmacogenomics, modern forensic science, molecular microbiology, and genetic diagnosis. Part three focuses on various everyday issues in a diagnostic laboratory, from genetic counseling and related ethical and psychological issues, to safety and quality management. Presents a comprehensive account of all new technologies and applications used in clinical diagnostic laboratories Explores a wide range of molecular-based tests that are available to assess DNA variation and changes in gene expression Offers clear translational presentations by the top molecular pathologists, clinical chemists, and molecular geneticists in the field

Advances in Evolutionary Computing

Advances in Evolutionary Computing
  • Author : Ashish Ghosh,Shigeyoshi Tsutsui
  • Publisher : Springer Science & Business Media
  • Release Date : 2002-11-26
  • Total pages : 1042
  • ISBN : 3540433309
  • File Size : 52,5 Mb
  • Total Download : 880
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This book provides a collection of fourty articles containing new material on both theoretical aspects of Evolutionary Computing (EC), and demonstrating the usefulness/success of it for various kinds of large-scale real world problems. Around 23 articles deal with various theoretical aspects of EC and 17 articles demonstrate the success of EC methodologies. These articles are written by leading experts of the field from different countries all over the world.

Henry's Clinical Diagnosis and Management by Laboratory Methods E-Book

Henry's Clinical Diagnosis and Management by Laboratory Methods E-Book
  • Author : Richard A. McPherson,Matthew R. Pincus
  • Publisher : Elsevier Health Sciences
  • Release Date : 2017-04-05
  • Total pages : 1700
  • ISBN : 9780323413152
  • File Size : 42,7 Mb
  • Total Download : 572
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Recognized as the definitive reference in laboratory medicine since 1908, Henry's Clinical Diagnosis continues to offer state-of-the-art guidance on the scientific foundation and clinical application of today's complete range of laboratory tests. Employing a multidisciplinary approach, it presents the newest information available in the field, including new developments in technologies and the automation platforms on which measurements are performed. Provides guidance on error detection, correction, and prevention, as well as cost-effective test selection. Features a full-color layout, illustrations and visual aids, and an organization based on organ system. Features the latest knowledge on cutting-edge technologies of molecular diagnostics and proteomics. Includes a wealth of information on the exciting subject of omics; these extraordinarily complex measurements reflect important changes in the body and have the potential to predict the onset of diseases such as diabetes mellitus. Coverage of today's hottest topics includes advances in transfusion medicine and organ transplantation; molecular diagnostics in microbiology and infectious diseases; point-of-care testing; pharmacogenomics; and the microbiome. Toxicology and Therapeutic Drug Monitoring chapter discusses the necessity of testing for therapeutic drugs that are more frequently being abused by users.

Molecular diagnostics for infectious diseases: Novel approaches, clinical applications and future challenges

Molecular diagnostics for infectious diseases: Novel approaches, clinical applications and future challenges
  • Author : Xiaogang Xu,Chao Zhuo,Bing Gu,Kamal El Bissati
  • Publisher : Frontiers Media SA
  • Release Date : 2023-03-31
  • Total pages : 193
  • ISBN : 9782832519493
  • File Size : 23,6 Mb
  • Total Download : 153
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PDF book entitled Molecular diagnostics for infectious diseases: Novel approaches, clinical applications and future challenges written by Xiaogang Xu,Chao Zhuo,Bing Gu,Kamal El Bissati and published by Frontiers Media SA which was released on 2023-03-31 with total hardcover pages 193, the book become popular and critical acclaim.

Neurodegenerative Diseases: Multifactorial Degenerative Processes, Biomarkers and Therapeutic Approaches (First Edition)

Neurodegenerative Diseases: Multifactorial Degenerative Processes, Biomarkers and Therapeutic Approaches (First Edition)
  • Author : Tabish Qidwai
  • Publisher : Bentham Science Publishers
  • Release Date : 2022-08-10
  • Total pages : 306
  • ISBN : 9789815040920
  • File Size : 52,9 Mb
  • Total Download : 703
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This reference is the definitive guide to common neurodegenerative diseases that affect humans. The book covers mechanisms of some of the most well-known neurodegenerative diseases, their biomarkers, neuropharmacology, and emerging treatment strategies. The book introduces the subject of neurodegeneration by outlining the biochemistry, pathophysiology and multifactorial neurological mechanisms (the role of genetics, environmental factors and mitochondrial damage, for example). Next, it explains some of the most studied diseases, namely, Parkinson’s Disease, Alzheimer’s Disease, Huntington’s Disease, and Multiple Sclerosis. Subsequent chapters delve into current knowledge about diagnostic and immunological biomarkers, followed by a summary of novel therapeutic strategies. Special attention has been given to the role of medicinal plants in attempting to treat neurodegenerative diseases, as well as the public health burden posed by these conditions. Key Features - give readers an overview of multifactorial disease mechanisms in neurodegeneration - covers some major neurodegenerative diseases in detail - covers diagnostic and immunological biomarkers - explores current therapeutic strategies and drug targets in common neurodegenerative diseases - offers a simple presentation with references for advanced readers The book is a suitable reference for all readers, including students, research scholars, and physicians who are interested in the mechanisms and treatment of neurodegenerative diseases.

Henry's Clinical Diagnosis and Management by Laboratory Methods: First South Asia Edition_e-Book

Henry's Clinical Diagnosis and Management by Laboratory Methods: First South Asia Edition_e-Book
  • Author : Richard A. McPherson
  • Publisher : Elsevier India
  • Release Date : 2016-08-31
  • Total pages : 1820
  • ISBN : 9788131246771
  • File Size : 10,9 Mb
  • Total Download : 887
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The book attempts to train a laboratory medicine student to achieve sound knowledge of analytical methods and quality control practices, to interpret the laboratory results, to distinguish the normal from the abnormal and to understand the merits and demerits of the assays under study.

Essential Concepts in Molecular Pathology

Essential Concepts in Molecular Pathology
  • Author : William B. Coleman,Gregory J. Tsongalis
  • Publisher : Academic Press
  • Release Date : 2019-11-23
  • Total pages : 634
  • ISBN : 9780128132586
  • File Size : 36,9 Mb
  • Total Download : 269
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Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today’s advances in pathology and medicine. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology

Fluorescence in situ Hybridization (FISH)

Fluorescence in situ Hybridization (FISH)
  • Author : Joanna M. Bridger,Keith Morris
  • Publisher : Humana
  • Release Date : 2016-08-23
  • Total pages : 451
  • ISBN : 1493957244
  • File Size : 9,8 Mb
  • Total Download : 376
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Fluorescence in situ Hybridization (FISH) belongs to that special category of well-established molecular biology techniques that, since their inception a few decades ago, have succeeded in keeping a prominent position within the constantly expanding list of laboratory pro- dures for biomedical research and clinical diagnostics. The design simplicity and cost-effectiveness of the early FISH protocols, combined with the signifcant acceleration of discoveries in related technical areas such as fuor- cence microscopy, digital imaging, and nucleic acid technology have prompted the div- sifcation of the original technique into an outstanding number of imaginative and useful applications, and thus have not only held back its outmoding but have also promoted its expansion into different areas of basic and applied research in the post-genomic era. The 34 chapters included in this book aim at portraying the vibrant complexity and diversity of the current FISH protocol landscape, providing cutting-edge examples of va- ous applications for genetic and developmental research, cancer research, reproductive medicine, diagnostic and prognostic purposes, microbial ecology, and evolutionary st- ies. The book is divided in four parts: (I) Core Techniques, (II) Technical Advancements and Novel Adaptations, (III) Translational FISH: Applications for Human Genetics and Medicine, and (IV) Protocols for Model Organisms.

Molecular Pathology, An Issue of Surgical Pathology Clinics, EBook

Molecular Pathology, An Issue of Surgical Pathology Clinics, EBook
  • Author : Lauren L. Ritterhouse
  • Publisher : Elsevier Health Sciences
  • Release Date : 2021-08-11
  • Total pages : 240
  • ISBN : 9780323794671
  • File Size : 19,6 Mb
  • Total Download : 846
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In this issue of Surgical Pathology Clinics, guest editor Lauren L. Ritterhouse brings her considerable expertise to the topic of molecular pathology. Provides in-depth, clinical reviews on molecular pathology, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

Great Warm Deserts of the World

Great Warm Deserts of the World
  • Author : Andrew Goudie
  • Publisher : Geomorphological Landscapes of
  • Release Date : 2002
  • Total pages : 490
  • ISBN : 0199245150
  • File Size : 20,8 Mb
  • Total Download : 509
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This is the first-ever regional study of the geomorphology of the world's deserts, demonstrating why different deserts have special landscape features and land-forming processes. It explains the climatic and tectonic history of deserts, showing how the histories of the deserts have been longand complex, and how they have responded to global changes in climate, particularly over the course of the last few millions of years. Each of the major warm deserts of the world is treated in detail, and the book is extensively illustrated with numerous plates and figures. A large andcomprehensive bibliography provides a guide to the international literature.

Diagnostic Molecular Pathology

Diagnostic Molecular Pathology
  • Author : William B. Coleman,Gregory J. Tsongalis
  • Publisher : Academic Press
  • Release Date : 2016-10-05
  • Total pages : 582
  • ISBN : 9780128011577
  • File Size : 46,6 Mb
  • Total Download : 941
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Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing is organized around disease types (genetic disease, infectious disease, neoplastic disease, among others). In each section, the authors provide background on disease mechanisms and describe how laboratory testing is built on knowledge of these mechanisms. Sections are dedicated to general methodologies employed in testing (to convey the concepts reflected in the methods), and specific description of how these methods can be applied and are applied to specific diseases are described. The book does not present molecular methods in isolation, but considers how other evidence (symptoms, radiology or other imaging, or other clinical tests) is used to guide the selection of molecular tests or how these other data are used in conjunction with molecular tests to make diagnoses (or otherwise contribute to clinical workup). In addition, final chapters look to the future (new technologies, new approaches) of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests. Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing contains exercises to test readers on their understanding of how molecular diagnostic tests are utilized and the value of the information that can be obtained in the context of the patient workup. Readers are directed to an ancillary website that contains supplementary materials in the form of exercises where decision trees can be employed to simulate actual clinical decisions. Focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis, and classification in the clinical workup of a patient Explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for prognostication of disease Features an ancillary website with self-testing exercises where decision trees can be employed to simulate actual clinical decisions Highlights new technologies and approaches of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests

A Fractal Analysis of Chemical Kinetics with Applications to Biological and Biosensor Interfaces

A Fractal Analysis of Chemical Kinetics with Applications to Biological and Biosensor Interfaces
  • Author : Ajit Sadana,Neeti Sadana,Richa Sadana
  • Publisher : Elsevier
  • Release Date : 2018-07-31
  • Total pages : 337
  • ISBN : 9780444638823
  • File Size : 15,6 Mb
  • Total Download : 361
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A Fractal Analysis of Chemical Kinetics with Applications to Biological and Biosensor Interfaces analyzes the kinetics of binding and dissociation of different analytes by different biosensor techniques, demonstrating and then comparing each. Emphasis is placed on newer instrumentation techniques, such as SPRi (surface plasmon resonance imaging), and classical techniques, such as SPR (surface plasmon resonance), and finally, DNA biosensors and nanobiosensors. In addition, a final capstone chapter includes biosensor economics. These topics are all covered in one comprehensive book in a way that cannot be found elsewhere. Analyzes the kinetics of binding on biosensor surfaces Presents and compares different biosensor techniques Provides insights into the binding and dissociation mechanisms of analytes on biosensor surfaces Links the heterogeneity of biosensor surfaces to dissociation rate coefficients

Landscape Ecology

Landscape Ecology
  • Author : Zev Naveh,Arthur S. Lieberman
  • Publisher : Springer
  • Release Date : 1984
  • Total pages : 386
  • ISBN : UOM:39015038856327
  • File Size : 25,8 Mb
  • Total Download : 133
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This series is dedicated to serving the growing community of scholars and practitioners concemed with the principles and applications of environ mental management. Each volume is a thorough treatment of a specific topic of importance for proper management practices. A fundamental objective of these books is to help the reader discem and implement man's stewardship of our environment and the world's renewable re sources. For we must strive to understand the relationship between man and nature, act to bring harmony to it, and nurture an environment that is both stable and productive. These objectives have often eluded us because the pursuit of other individual and societal goals has diverted us from a course of living in balance with the environment. At times, therefore, the environmental manager may have to exert restrictive control, which is usually best applied to man, not nature. Attempts to alter or hamess nature have often failed or backfired, as exemplified by the results of imprudent use of herbicides, fertilizers, water, and other agents. Each book in this series will shed light on the fundamental and applied aspects of environmental management. It is hoped that each will help solve a practical and serious environmental problem.

Practical Oncologic Molecular Pathology

Practical Oncologic Molecular Pathology
  • Author : Yi Ding,Linsheng Zhang
  • Publisher : Springer Nature
  • Release Date : 2021-07-10
  • Total pages : 449
  • ISBN : 9783030732271
  • File Size : 21,6 Mb
  • Total Download : 108
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This book is a review and high-yield reference on the clinical molecular diagnostics of malignant neoplasms. It aims to address the practical questions frequently encountered in the molecular oncology practice, as well as key points and pitfalls in the clinical interpretation of molecular tests in guiding precision cancer management. The text uses a Q&A format and case presentations, with emphasis on understanding the molecular test methods, diagnosis, classification, risk assessment and clinical correlation. Starting with an update on the molecular biology of cancer, the book focuses on the topics related to molecular diagnostics and genetics-based precision oncology. Separate chapters are dedicated to discussion of the bioinformatics for the analysis of genetic/genomic data generated from molecular assays, and quality control (QC)/quality assurance (QA) programs in the clinical laboratories; both are critical in producing high quality results for clinical care of cancer patients. These are followed by organ system-based reviews and discussions on the molecular genetic abnormalities and related tests covering diverse types of common to rare malignant neoplasms. This book also provides up-to-date knowledge related to malignant neoplasms, discusses the established as well as evolving requirements for pathologic diagnosis of these malignancies. It also discusses the cost effective utilization of molecular tests in clinical oncology. Written by experts in the field, Practical Oncologic Molecular Pathology serves as a valuable reference for practicing pathologists, fellows, residents and other health care professionals.