Comparative Mammalian Immunology

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• Author : Ian R. Tizard
• Publisher : Elsevier
• Release Date : 2023-02-17
• Total pages : 460
• ISBN : 9780323952200
• File Size : 21,9 Mb
• Total Download : 705
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Download Comparative Mammalian Immunology in PDF, Epub, and Kindle

Comparative Mammalian Immunology: The Evolution and Diversity of the Immune Systems of Mammals provides a review on the current knowledge of mammalian immune systems from a comparative viewpoint. This reference encompasses recent work on the immune systems of marine mammals, bats and marsupials in addition to other lesser-known species, with the immune systems of humans and laboratory mice as components of chapters on primates and rodents respectively. The book also makes use of the most recent studies on the genomic sequences of the mammals to identify both common and unique features of each mammal's immune system. The book elucidates the complex, but coordinated and controlled series of interactions involving cells and molecules that has evolved to protect the host against disease. Mammals consist of a highly diverse group of animals in which the immune system has been subjected to a variety of selective pressures. This is reflected in differences in the organization and function of their immune systems, and is especially seen in those gene families characterized by complexity and polymorphism. Demonstrates multiple diverse pathways and mechanisms to optimize resistance and survival in the face of infectious diseases Shows the clear patterns of emergence of different immunologic traits among the diverse orders of mammals Reflects issues with innate or adaptive immune systems Serves as a comprehensive review of the current state of knowledge of the immune system of each mammalian order

• Author : R. J. Turner
• Publisher : John Wiley & Sons Incorporated
• Release Date : 1994-08-08
• Total pages : 222
• ISBN : UOM:39015032549845
• File Size : 9,9 Mb
• Total Download : 437
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Download Immunology in PDF, Epub, and Kindle

This text is aimed at those students and research workers who have some knowledge of immunology, but are curious about the advances, opportunities and challenges in comparative work. It answers questions about the similarities between different orders, classes, phyla and kingdoms.

• Author : Edwin L. Cooper
• Publisher : Springer
• Release Date : 2018-08-07
• Total pages : 1048
• ISBN : 9783319767680
• File Size : 30,7 Mb
• Total Download : 294
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Download Advances in Comparative Immunology in PDF, Epub, and Kindle

Immunologists, perhaps understandably, most often concentrate on the human immune system, an anthropocentric focus that has resulted in a dearth of information about the immune function of all other species within the animal kingdom. However, knowledge of animal immune function could help not only to better understand human immunology, but perhaps more importantly, it could help to treat and avoid the blights that affect animals, which consequently affect humans. Take for example the mass death of honeybees in recent years – their demise, resulting in much less pollination, poses a serious threat to numerous crops, and thus the food supply. There is a similar disappearance of frogs internationally, signaling ecological problems, among them fungal infections. This book aims to fill this void by describing and discussing what is known about non-human immunology. It covers various major animal phyla, its chapters organized in a progression from the simplest unicellular organisms to the most complex vertebrates, mammals. Chapters are written by experts, covering the latest findings and new research being conducted about each phylum. Edwin L. Cooper is a Distinguished Professor in the Laboratory of Comparative Immunology, Department of Neurobiology at UCLA’s David Geffen School of Medicine.

• Author : L. Du Pasquier,G.W. Litman
• Publisher : Springer Science & Business Media
• Release Date : 2012-12-06
• Total pages : 326
• ISBN : 9783642596742
• File Size : 13,5 Mb
• Total Download : 970
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Download Origin and Evolution of the Vertebrate Immune System in PDF, Epub, and Kindle

The comparative approach to immunology can be traced to the era of Pasteur and Metchnikov in which observations regarding foreign recognition in invertebrates was a factor in the develop ment of the principal concepts that created the foundation of what now is the broad field of immunology. With each major experimental and conceptual breakthrough, the classical, albeit essential, question has been asked "are the immune systems of phylogenetically primitive vertebrates and invertebrates similar to that of mammals?" Somewhat surprisingly for the jawed verte brates, the general answer has been a qualified form of "yes", whereas for agnathans and invertebrate phyla it has been "no" so far. The apparent abruptness in the appearance of the immune system of vertebrates is linked to the introduction of the somatic generation of the diversity of its antigen specific receptors. Therefore the questions regarding the origin and evolution of the specific immune system revolve around this phenomenon. With respect to the origin of the system (aside from the or igin of the rearranging machinery itself, the study of which is still in its infancy) one can ask questions about the cellular and mo lecular contexts in which the mechanism was introduced.

• Author : Edwin Lowell Cooper
• Publisher : Prentice Hall
• Release Date : 1976
• Total pages : 360
• ISBN : UOM:39015004398296
• File Size : 53,9 Mb
• Total Download : 107
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Download Comparative Immunology in PDF, Epub, and Kindle

PDF book entitled Comparative Immunology written by Edwin Lowell Cooper and published by Prentice Hall which was released on 1976 with total hardcover pages 360, the book become popular and critical acclaim.

• Author : Davide Malagoli
• Publisher : Academic Press
• Release Date : 2016-07-21
• Total pages : 384
• ISBN : 9780128020135
• File Size : 43,9 Mb
• Total Download : 860
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Download The Evolution of the Immune System in PDF, Epub, and Kindle

The Evolution of the Immune System: Conservation and Diversification is the first book of its kind that prompts a new perspective when describing and considering the evolution of the immune system. Its unique approach summarizes, updates, and provides new insights on the different immune receptors, soluble factors, and immune cell effectors. Helps the reader gain a modern idea of the evolution of the immune systems in pluricellular organisms Provides a complete overview of the most studied and hot topics in comparative and evolutionary immunology Reflects the organisation of the immune system (cell-based, humoral [innate], humoral [adaptive]) without introducing further and misleading levels of organization Brings concepts and ideas on the evolution of the immune system to a wide readership

• Author : Vaclav Vetvicka,P. Sima
• Publisher : Birkhäuser
• Release Date : 2012-12-06
• Total pages : 201
• ISBN : 9783034888356
• File Size : 43,7 Mb
• Total Download : 800
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Download Evolutionary Mechanisms of Defense Reactions in PDF, Epub, and Kindle

At present, we do not fully understand at what stage of the evolution of living matter the first traces of defense reactions occurred. We even do not fully understand how and why immune systems reached their contem porary state in advanced vertebrates and man. It may be expected that in the near future these questions will be answered by comparative and develop mental biology. Together with an extraordinary explosion of our knowledge about immunity of mammals including man, an increase in the interests concerning origin and development of immune mechanisms at lower stages of the phylogeny can be observed. The search for simple types of immune mechanisms in less complex but still evolutionary successful animals is promising and may contribute to better understanding of highly complex immune adaptive responses in mammals. It is important to note that comparative and evolutionary immunology differs greatly from other branches of biomedical science. Apart from immunology and molecular biology, a specialist in this discipline has to be familiar with every detail of taxonomy, comparative anatomy, physiology, embryology, and even with the phyletic relationships of animals. Probably no monography could deal with the entire animal kingdom, because, in many cases, the insights into questions about immune mecha nisms of many animal groupings or phyla, and their possible evolutionary implications, are unknown or just now beginning to take shape. For the moment, our knowledge on such matters relies upon reconstructions of ideas that we have deduced from studies on members of relative taxa.

• Author : Sylvia L. Smith,Robert B. Sim,Martin F. Flajnik
• Publisher : CRC Press
• Release Date : 2014-12-04
• Total pages : 328
• ISBN : 9781466595743
• File Size : 39,7 Mb
• Total Download : 848
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Download Immunobiology of the Shark in PDF, Epub, and Kindle

Immunity studies in sharks over the past three decades have produced some remarkable discoveries. If one message rings true, it is that alternative animal model systems, such as sharks and their relatives, have contributed very substantially to a better understanding of the development evolution of our own immune system. Immunobiology of the Shark describes the cellular, genetic, and molecular specifics of immune systems in sharks. Diverse approaches were employed to study the immunobiology of the shark from basic microscopic observations to detailed genome annotation. The book also raises a series of fascinating questions, which can be addressed experimentally using today’s technology. This book will be a valuable resource for mainstream immunologists, comparative immunologists, geneticists, ecologists, evolutionary biologists, and investigators engaged in shark research. The book also aims to illustrate the magnificence of these animals as model systems and underscores the importance of their study to further understand their complex, and often enigmatic, biology.

• Author : Bernd Kaspers,Karel A. Schat,Thomas Göbel,Lonneke Vervelde
• Publisher : Academic Press
• Release Date : 2021-12-05
• Total pages : 626
• ISBN : 9780128190715
• File Size : 12,5 Mb
• Total Download : 705
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Download Avian Immunology in PDF, Epub, and Kindle

Avian Immunology, Third Edition contains a detailed description of the avian innate immune system, encompassing the mucosal, enteric, respiratory and reproductive systems. The diseases and disorders it covers, include immunodepressive diseases and immune evasion, autoimmune diseases, and tumors of the immune system. Practical aspects of vaccination are examined as well. Extensive appendices summarize resources for scientists including cell lines, inbred chicken lines, cytokines, chemokines, and monoclonal antibodies. With contributions from the foremost international experts in the field, Avian Immunology 3rd, provides the most up-to-date crucial information not only for poultry health professionals and avian biologists, but also for comparative and veterinary immunologists, graduate students and veterinary students with an interest in avian immunology. Avian Immunology, Third Edition, is a fascinating and growing field and surely provides new and exciting insights for mainstream immunology in the future. Reflects significant advances in the field since the second edition, particularly the explosion of knowledge on genomics including work on the chicken, turkey and zebra finch genomes Provides a single source reference ranging from the basic science to cutting edge research Provides practical information for veterinarians particularly those specialised in poultry or companion bird medicine New chapters on the impact of the microbiome on the immune system, defence mechanisms in the egg and embryo and emerging transgene technologies

• Author : Margaret J. Manning,Rodney J. Turner
• Publisher : John Wiley & Sons
• Release Date : 1976
• Total pages : 206
• ISBN : UCAL:B4564354
• File Size : 48,9 Mb
• Total Download : 920
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Download Comparative Immunobiology in PDF, Epub, and Kindle

PDF book entitled Comparative Immunobiology written by Margaret J. Manning,Rodney J. Turner and published by John Wiley & Sons which was released on 1976 with total hardcover pages 206, the book become popular and critical acclaim.

• Author : Bonnie S. Dunbar,M.G. O'Rand
• Publisher : Springer
• Release Date : 2013-05-31
• Total pages : 458
• ISBN : 147578984X
• File Size : 47,9 Mb
• Total Download : 409
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Download A Comparative Overview of Mammalian Fertilization in PDF, Epub, and Kindle

In 1964, the Fertilization and Gamete Physiology Research Training Program (FERGAP) was established at the Marine Biological Laboratories, Woods Hole, Massachusetts. Over the course of the next 12 years, under the directorship of Dr. Charles B. Metz, FERGAP brought together, trained, and inspired a generation of students in reproductive biology from all over the world. As students of C. B. Metz and as FERGAP trainees, we would like to dedicate this collected work on comparative mammalian fertilization to our teacher and mentor, Dr. Charles B. Metz. Like a number of authors contributing to this volume, we have been struck by the significant impact that C. B. Metz and FERGAP had on the development of students of reproductive biology. Applying both the classical and molecular techniques of cell biology and immunology to problems of gamete biology, Dr. Metz emphasized a comparative and analytical approach that was reflected in his own research on fertilization in Paramecia, sea urchins, frogs, and mammals. It is hoped that this volume will serve to stimulate students to discover the myriad of fascinating research problems in gamete and reproductive biology. Bonnie S. Dunbar Michael G. O'Rand Houston, Texas Chapel Hill, North Carolina ix Contents Part I COMPARATIVE OVERVIEW OF MAMMALIAN GAMETES The Coevolution of Mammalian Gametes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 J. Michael Bedford I. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2. Gamete Design . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 2.1. Monotremes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 . . . . . . . . . . . . . . 2.2. Marsupials . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 . . . . . . . . . . . . . . . 2.3. Eutherians . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 3. Gamete Maturation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 . . . . . . . . . . . . . . . 3 .1. Oocyte Maturation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 . . . . . . . . . . . . . 3.2. Sperm Maturation in the Male . . . . . . . . . . . . . . . . . . . . . . . 15 . . . . . . . . . .

• Author : Huw C. Davies
• Publisher : Springer
• Release Date : 1997-01-01
• Total pages : 394
• ISBN : 0412372401
• File Size : 30,6 Mb
• Total Download : 112
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Download Introductory Immunobiology in PDF, Epub, and Kindle

Why immunobiology? Immunology is the study of the immune system - the internal defence reactions that protect the body from invading microorganisms and the diseases they cause. Spectacular advances have been made over the last few decades in understanding how the immune system works. There is no doubt that these advances have been made possible by concentrating research on a few species of animals, most notably mouse and man. The main motiva tion for studying the human system, for example, has been to further the cause of medicine. Indeed, the roots of modern immunology can be traced back to pioneering studies of vaccines against viruses and bacteria. The vaccine n. a mouse has become the favoured non-human animal in which to study preparation, usually derived from an immunity, both in relation to protection from microorganisms, but also at infectious pathogen, a more fundamental level. The term 'immunology' has become virtually administered to provide synonymous with the study of the immune systems of humans and mice. protective immunity without causing disease. 'Immunobiology' in contrast is a broader field, encompassing the immune systems of all animals. Ids the study of the origins and evolution ofimmune systems in general, and the underlying role that microorganisms play in the microorganism n. an process. organism too small to be seen clearly with the The penalty for this focussed effort has been a disproportionately naked eye; often used mammalocentric database.

• Author : Jordi Agustí,Mauricio Antón
• Publisher : Columbia University Press
• Release Date : 2002
• Total pages : 356
• ISBN : 0231116403
• File Size : 18,5 Mb
• Total Download : 567
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Download Mammoths, Sabertooths, and Hominids in PDF, Epub, and Kindle

This book covers mammalian evolution from the aftermath of the dinosaur extinction to the glacial climax of the Pleistocene epoch, from early lemur-like primates to giant cold-climate adapted mega-mammals, such as the woolly mammoth or mastodon.

• Author : Galina A. Klevezal,M.V. Mina
• Publisher : CRC Press
• Release Date : 1995-06-01
• Total pages : 290
• ISBN : 9054106212
• File Size : 28,9 Mb
• Total Download : 466
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Download Recording Structures of Mammals in PDF, Epub, and Kindle

This text focuses on the principles and methods of using growth layers formed in teeth and bones of mammals to make a judgement on essential traits of the animal's life history. In nearly all mammalian species, including man, the age of individuals can be determined from the number of growth layers and, at least in some of them, it is possible to estimate the season of an animal's birth and death, age of sexual maturation, periodicity of reproduction, certain feeding habits and other aspects of the individual's biology. It is also possible, from tooth-enamel analysis, to assess doses of radiation accumulated by animals and human beings during their lifetime.;This book is intended for zoologists, wild-game biologists and zoo archaeologists, but some of the sections could also be of interest for anthropologists, radioecologists and conservation biologists.

• Author : John K-J Li
• Publisher : CRC Press
• Release Date : 1995-12-05
• Total pages : 176
• ISBN : 0849301696
• File Size : 26,8 Mb
• Total Download : 105
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Download Comparative Cardiovascular Dynamics of Mammals in PDF, Epub, and Kindle

Comparative Cardiovascular Dynamics of Mammals offers never-before-published data on the structure and function of the circulatory systems of the different mammalian species. This text explores classic allometry, dimensional analysis, and modern hemodynamics to establish similarity principles that provide a necessary and important step in understanding the natural common design and functional features of the cardiovascular systems of different mammals. Fluid and blood vessel mechanics, pulse transmission characteristics, cardiac energetics and mechanics, as well as heart-arterial system interaction are included in this essential reference. The sensitivity of parameters and similarity of principles in the diagnosis of cardiovascular diseases are also addressed. This book also describes the natural processes involved in the functional development of the mammalian cardiovascular system. By using modern methods to present recent findings on the similarities and differences of the mammalian cardiovascular system, the author provides an easily understood approach to this dynamic field of study.

• Author : James R. Miller
• Publisher : Cambridge University Press
• Release Date : 1990
• Total pages : 230
• ISBN : 0521373891
• File Size : 15,8 Mb
• Total Download : 755
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Download X-Linked Traits in PDF, Epub, and Kindle

This book provides a source of information on comparative aspects of mammalian genomes.

• Author : Jessica H. Lewis,James H. Lewis
• Publisher : Springer Science & Business Media
• Release Date : 1996-05-31
• Total pages : 456
• ISBN : UOM:39015035741167
• File Size : 45,8 Mb
• Total Download : 486
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Download Comparative Hemostasis in Vertebrates in PDF, Epub, and Kindle

The author examines hemostasis in animals from all seven major vertebrate classes. Her research provides unique insights into the phylogenetic development of the various phases and components of hemostasis. This monograph is a valuable reference for students, researchers, and teachers of biology, zoology, veterinary science, and human medicine.

• Author : Azad K. Kaushik,Yfke Pasman
• Publisher : CRC Press
• Release Date : 2014-05-01
• Total pages : 264
• ISBN : 9781482243550
• File Size : 51,9 Mb
• Total Download : 776
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Download Comparative Immunoglobulin Genetics in PDF, Epub, and Kindle

This contemporary book covers significant new knowledge that has emerged during the last two decades and, thus, provides novel antibody phylogenetic perspectives relevant to development of new antibody-based therapeutics and vaccines. It fills a much-needed niche in the area of immunoglobulin genetics across species from a comparative perspective. New insights and perspectives from immunoglobulin genetics from species such as sea lamprey, cattle, marsupial, bat, rat, rabbit, and swine—other species than the traditional subjects of mice and humans—are relevant to antibody design and engineering. These new perspectives find direct application in the cutting-edge areas of antibody design, engineering and therapeutics, antibody-drug conjugates, and novel antibody-based vaccines. This book fills the need to provide updated knowledge of this newly exploded area that is finding applications in new drug development. No other competing books on the topic are available in the market. The book will be of great interest to immunologists, immunology researchers, immunogeneticists, researchers in pharmaceutical science, those involved in the infectious disease and antibody therapeutics areas, and many others.

• Author : Terry A. Vaughan,James Michael Ryan,Nicholas J. Czaplewski
• Publisher : Cengage Learning
• Release Date : 2000
• Total pages : 680
• ISBN : UOM:39015073620745
• File Size : 46,9 Mb
• Total Download : 215
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Download Mammalogy in PDF, Epub, and Kindle

This is the long-awaited revision of the best-selling classic mammalogy text. The biology of mammals is viewed from a broad range of perspectives, making it useful to instructors with contrasting approaches to the subject. Based on the extensive studies of researchers, MAMMALOGY holds the interest of students, while maintaining the respect of the members of the scholarly community of mammalogists. The topics covered were chosen as the most important, interesting, and essential to the understanding of mammals.

• Author : Ivan Lefkovits,Herman Waldmann
• Publisher : Oxford University Press, USA
• Release Date : 1999
• Total pages : 312
• ISBN : UOM:39015047480572
• File Size : 20,8 Mb
• Total Download : 102
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Download Limiting Dilution Analysis of Cells of the Immune System in PDF, Epub, and Kindle

This new edition is an extensive treatise on the rationale of limiting dilution analysis (LDA). LDA has evolved from its previous role as a basic research laboratory tool in virology and immunology to one pertaining to many different research disciplines and to clinical applications. Newmethodologies (such as PCR, confocal microscopy, in situ hybridisation) have emerged, with the result that single-cell assays can now be performed on a more defined basis, and the quantitation of cells and their precursors is now more accessible to the limiting dilution approach. This book includesboth detailed mathematical derivations and methodological descriptions so that the uninitiated scientist can set up and evaluate limiting dilution experiments without further instruction. It also describes particular examples of how LDA is being used to determine clinical practice. The secondedition of this highly successful book, which has been on the shelf of every modern immunology laboratory for the last two decades, retains the same overall structure of the first edition, with one important addition - an extensive LDA software package. The LDA program and the simulation softwarewill be linked to a web site to ensure updates at regular intervals. The first edition was written primarily for immunologists, but this volume has been expanded so that it will be useful to a broader audience in microbiology, pathology, virology and cellular biology. Furthermore, this volume isintended to be used as additional reading for students of biology and medicine whose knowledge of the applications of Poisson distribution need refreshing.

• Author : Loriano Ballarin,Matteo Cammarata
• Publisher : Academic Press
• Release Date : 2016-04-08
• Total pages : 324
• ISBN : 9780128032534
• File Size : 28,8 Mb
• Total Download : 502
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Download Lessons in Immunity in PDF, Epub, and Kindle

Lessons in Immunity: From Single-cell Organisms to Mammals stems from the activity of the Italian Association of Developmental and Comparative Immunobiology (IADCI), represented by the editors. This book is presented as a series of short overviews that report on the current state of various relevant fields of immunobiology from an evolutionary perspective. The overviews are written by authors directly involved in the research, and most are members of the IADCI or have otherwise been involved in the related research for their respective overview. This publication offers scientists and teachers an easy and updated reference tool. Provides simple and updated reviews on the immunobiology of a wide spectrum of organisms, considered in an evolutionary context Focuses on both cells and humoral components of a variety of non-classical model organisms Offers in a single volume many contributions which can help with understanding the evolution of immune responses and the main adaptations in animal phyla Presents a valuable holistic cross-sectional approach for teaching immunology and its applications