Biomaterials And Medical Device Associated Infections

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• Author : L Barnes,Ian Cooper
• Publisher : Elsevier
• Release Date : 2014-11-21
• Total pages : 278
• ISBN : 9780857097224
• File Size : 38,8 Mb
• Total Download : 265
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Download Biomaterials and Medical Device - Associated Infections in PDF, Epub, and Kindle

Despite advances in materials and sterilisation, patients who receive biomaterials of medical device implants are still at risk of developing an infection around the implantation site. This book reviews the fundamentals of biomaterials and medical device related infections and methods and materials for the treatment and prevention of infection. The first part of the book provides readers with an introduction to the topic including analyses of biofilms, diagnosis and treatment of infection, pathology and topography. The second part of the book discusses a range of established and novel technologies and materials which have been designed to prevent infection. Provides analysis of biofilms and their relevance to implant associated infections. Assesses technologies for controlling biofilms. Considers advantages and disadvantages of in vivo infection studies.

• Author : Fintan Moriarty,Sebastian A.J. Zaat,Henk J. Busscher
• Publisher : Springer Science & Business Media
• Release Date : 2012-09-29
• Total pages : 566
• ISBN : 9781461410317
• File Size : 40,6 Mb
• Total Download : 195
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Download Biomaterials Associated Infection in PDF, Epub, and Kindle

Biomaterials associated infection (BAI) is one of the most common complications associated with implantation of any biomaterial regardless of form or function. These infections usually involve bacterial colonization and biofilm formation on the biomaterial itself, rendering the infection impervious to antimicrobials and host defenses. In addition, it is becoming increasingly clear that infection of the surrounding tissues also plays an important role in BAI, and that the infection may be influenced by the composition and design of the implanted biomaterial. In this book, worldwide leaders in the field address this critical problem in the translation of biomaterials research into clinical practice. The book begins with an emphasis on the latest research in the pathogenesis of BAI from microbiological, immunological, and materials science perspectives. The current state of the art in antimicrobial activation of biomaterials through surface modification and the incorporation of antimicrobial agents is then discussed. In the concluding chapters, successful translation of a selection of antimicrobial technologies from preclinical research into clinical use is described alongside a discussion of the utility of these devices and perspectives for future development. This book is essential reading for researchers and clinicians who are interested in understanding the fundamentals of BAI, the latest in antimicrobial materials research, and the state of the art in clinically available antimicrobial containing medical devices.

• Author : Ying Deng,Wei Lv
• Publisher : Woodhead Publishing
• Release Date : 2016-10-24
• Total pages : 238
• ISBN : 9780081003985
• File Size : 30,9 Mb
• Total Download : 327
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Download Biofilms and Implantable Medical Devices in PDF, Epub, and Kindle

Biofilms and Implantable Medical Devices: Infection and Control explores the increasing use of permanent and semi-permanent implants and indwelling medical devices. As an understanding of the growth and impact of biofilm formation on these medical devices and biomaterials is vital for protecting the health of the human host, this book provides readers with a comprehensive treatise on biofilms and their relationship with medical devices, also reporting on infections and associated strategies for prevention. Provides useful information on the fundamentals of biofilm problems in medical devices Discusses biofilm problems in a range of medical devices Focuses on strategies for prevention of biofilm formation

• Author : Sina Ebnesajjad
• Publisher : Elsevier Inc. Chapters
• Release Date : 2013-12-05
• Total pages : 368
• ISBN : 9780128076682
• File Size : 9,8 Mb
• Total Download : 132
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Download Handbook of Polymer Applications in Medicine and Medical Devices in PDF, Epub, and Kindle

This chapter focuses on adhesives used in direct physiological contact in dental and medical procedures. Activity in both areas has been quite extensive outside the United States for decades. In contrast, adhesive use in medical devices, patches, and plasters has been ongoing in the United States for a long time. In the case of medical devices, adhesion is concerned with the joining of materials such as plastics, elastomers, textiles, metals, and ceramics, which are examined in other chapters of the present volume and are covered in various references [1–6], The coverage of this chapter is devoted to applications where to adhesives are in direct contact with tissues and other live organs.

• Author : Natália Martins,Célia F. Rodrigues
• Publisher : MDPI
• Release Date : 2020-12-23
• Total pages : 204
• ISBN : 9783039434381
• File Size : 14,5 Mb
• Total Download : 333
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Download Biomaterial-Related Infections in PDF, Epub, and Kindle

The use of medical devices (e.g., catheters, implants, and probes) is a common and essential part of medical care for both diagnostic and therapeutic purposes. However, these devices quite frequently lead to the incidence of infections due to the colonization of their abiotic surfaces by biofilm-growing microorganisms, which are progressively resistant to antimicrobial therapies. Several methods based on anti-infective biomaterials that repel microbes have been developed to combat device-related infections. Among these strategies, surface coating with antibiotics (e.g., beta-lactams), natural compounds (e.g., polyphenols), or inorganic elements (e.g., silver and copper nanoparticles) has been widely recognized as exhibiting broad-spectrum bactericidal or bacteriostatic activity. So, in order to achieve a better therapeutic response, it is crucial to understand how these infections are different from others. This will allow us to find new biomaterials characterized by antifouling coatings with repellent properties or low adhesion towards microorganisms, or antimicrobial coatings that are capable of killing microbes approaching the surface, improving biomaterial functionalization strategies and supporting tissues’ bio-integration.

• Author : G. Rakhorst,Rutger Jan Ploeg
• Publisher : World Scientific
• Release Date : 2008
• Total pages : 279
• ISBN : 9789812709561
• File Size : 24,8 Mb
• Total Download : 739
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Download Biomaterials in Modern Medicine in PDF, Epub, and Kindle

Design of biomedical products / G.J. Verkerke & E.B. van der Houwen -- Animal models in biomaterials research / G. Rakhorst ... [et al.] -- Technology assessment / J.M. Hummel -- Hemocompatibility of medical devices / W. van Oeveren -- Tissue and cell interactions with (bio)materials / T.G. van Kooten & R. Kuijer -- Biomaterials-associated surgery and infection / P.G.M. Maathuis ... [et al.] -- Cardiopulmonary bypass and postoperative organ dysfunction / Y.J. Gu -- Mechanical circulatory support systems / G. Rakhorst & M.E. Erasmus -- Biomaterials-related infections in orthopedic implants / D. Neut & R.L. Diercks -- Biomaterials for voice reconstruction / G.J. Verkerke ... [et al.] -- Biomaterials in ophthalmology / V.W. Renardel de Lavalette & S.A. Koopmans -- Biomaterials in plastic surgery / M.F. Meek -- Surgical meshes : morphology-dependent bacterial colonization / A.F. Engelsman

• Author : Paul Stoodley,Luanne Hall-Stoodley,Bill Costerton,Patrick DeMeo,Mark Shirtliff,Ellen Gawalt,Sandeep Kathju
• Publisher : Elsevier Inc. Chapters
• Release Date : 2013-12-05
• Total pages : 368
• ISBN : 9780128076675
• File Size : 13,8 Mb
• Total Download : 307
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Download Handbook of Polymer Applications in Medicine and Medical Devices in PDF, Epub, and Kindle

The initial design criteria in the choice of indwelling materials for medical and dental purposes may be pragmatic, and based on the necessary mechanical properties required to fashion a functional device. Orthopedic implants require strong materials for weight-bearing, and articulating surfaces such as joints require durability and resistance to wear. Stents and shunts require flexibility and patency, and sutures require a high tensile strength yet also must be flexible enough for intricate manipulation. As the devices became more sophisticated and developments in materials science provided more options for manufacture, implants are being used more frequently and with longer anticipated lifetimes. Concurrently, the design process increasingly incorporated biocompatibility and comfort into the design criteria. However, with longer lifetimes, the more frequent use of invasive surgical procedures involving indwelling devices and biologically-friendly materials, there has been a rise in the number of incidences of device-related infection. Urinary catheters have been estimated to account for 30% of all nosocomial infections [1]. Between 66 and 88% of these occur after urinary catheterization [2]. It is also reported that almost 100% of catheterized patients develop an infection in an openly draining indwelling catheter which has been in place for four days or more [2]. For some procedures, such as orthopedic joint arthroplasties, the diagnosed surgical site infection rates are relatively low (between 1% and 2%; [3]); however, the increasing number of patients undergoing joint-replacement surgery translates to large numbers of patients afflicted with the consequences of complicating infections per year. Furthermore, infection of artificial joints can be devastating, since oral or IV antibiotic therapy frequently fails to resolve the infection, with the only remaining course of action being surgical debridement or partial or total revision. These two examples, the first with very high numbers of patients but of lesser severity in terms of impact to the individual, and the second, low numbers but severe patient impact, reflect the incentive to pursue a third design criteria—that of infection resistance—into materials and devices [4]. In the following sections we will discuss the role of bacterial biofilms in infection, and the growing literature highlighting biofilms as an important cause of device-related infection.

• Author : Célia F. Rodrigues,Natália Martins
• Publisher : Unknown
• Release Date : 2020
• Total pages : 204
• ISBN : 303943439X
• File Size : 31,6 Mb
• Total Download : 568
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Download Biomaterial-Related Infections in PDF, Epub, and Kindle

The use of medical devices (e.g., catheters, implants, and probes) is a common and essential part of medical care for both diagnostic and therapeutic purposes. However, these devices quite frequently lead to the incidence of infections due to the colonization of their abiotic surfaces by biofilm-growing microorganisms, which are progressively resistant to antimicrobial therapies. Several methods based on anti-infective biomaterials that repel microbes have been developed to combat device-related infections. Among these strategies, surface coating with antibiotics (e.g., beta-lactams), natural compounds (e.g., polyphenols), or inorganic elements (e.g., silver and copper nanoparticles) has been widely recognized as exhibiting broad-spectrum bactericidal or bacteriostatic activity. So, in order to achieve a better therapeutic response, it is crucial to understand how these infections are different from others. This will allow us to find new biomaterials characterized by antifouling coatings with repellent properties or low adhesion towards microorganisms, or antimicrobial coatings that are capable of killing microbes approaching the surface, improving biomaterial functionalization strategies and supporting tissues' bio-integration.

• Author : Sophie Lerouge,Anne Simmons
• Publisher : Elsevier
• Release Date : 2012-09-27
• Total pages : 352
• ISBN : 9780857096265
• File Size : 55,7 Mb
• Total Download : 474
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Download Sterilisation of Biomaterials and Medical Devices in PDF, Epub, and Kindle

The effective sterilisation of any material or device to be implanted in or used in close contact with the human body is essential for the elimination of harmful agents such as bacteria. Sterilisation of biomaterials and medical devices reviews established and commonly used technologies alongside new and emerging processes. Following an introduction to the key concepts and challenges involved in sterilisation, the sterilisation of biomaterials and medical devices using steam and dry heat, ionising radiation and ethylene oxide is reviewed. A range of non-traditional sterilisation techniques, such as hydrogen peroxide gas plasma, ozone and steam formaldehyde, is then discussed together with research in sterilisation and decontamination of surfaces by plasma discharges. Sterilisation techniques for polymers, drug-device products and tissue allografts are then reviewed, together with antimicrobial coatings for ‘self-sterilisation’ and the challenge presented by prions and endotoxins in the sterilisation of reusable medical devices. The book concludes with a discussion of future trends in the sterilisation of biomaterials and medical devices. With its distinguished editors and expert team of international contributors, Sterilisation of biomaterials and medical devices is an essential reference for all materials scientists, engineers and researchers within the medical devices industry. It also provides a thorough overview for academics and clinicians working in this area. Reviews established and commonly used technologies alongside new and emerging processes Introduces and reviews the key concepts and challenges involved in sterilisation Discusses future trends in the sterilisation of biomaterials and medical devices

• Author : Webb
• Publisher : Oxford University Press
• Release Date : 2020-01-10
• Total pages : 1961
• ISBN : 9780198855439
• File Size : 15,5 Mb
• Total Download : 226
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Download Oxford Textbook of Critical Care in PDF, Epub, and Kindle

Now in paperback, the second edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely this text takes a problem-orientated approach providing a key resource for daily clinical issues in the intensive care unit. The text is organized into short topics allowing readers to rapidly access authoritative information on specific clinical problems. Each topic refers to basic physiological principles and provides up-to-date treatment advice supported by references to the most vital literature. Where international differences exist in clinical practice, authors cover alternative views. Key messages summarise each topic in order to aid quick review and decision making. Edited and written by an international group of recognized experts from many disciplines, the second edition of the Oxford Textbook of Critical Careprovides an up-to-date reference that is relevant for intensive care units and emergency departments globally. This volume is the definitive text for all health care providers, including physicians, nurses, respiratory therapists, and other allied health professionals who take care of critically ill patients.

• Author : Ferdyansyah Mahyudin,Hendra Hermawan
• Publisher : Springer
• Release Date : 2016-02-26
• Total pages : 242
• ISBN : 9783319148458
• File Size : 27,8 Mb
• Total Download : 315
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Download Biomaterials and Medical Devices in PDF, Epub, and Kindle

This book presents an introduction to biomaterials with the focus on the current development and future direction of biomaterials and medical devices research and development in Indonesia. It is the first biomaterials book written by selected academic and clinical experts experts on biomaterials and medical devices from various institutions and industries in Indonesia. It serves as a reference source for researchers starting new projects, for companies developing and marketing products and for governments setting new policies. Chapter one covers the fundamentals of biomaterials, types of biomaterials, their structures and properties and the relationship between them. Chapter two discusses unconventional processing of biomaterials including nano-hybrid organic-inorganic biomaterials. Chapter three addresses biocompatibility issues including in vitro cytotoxicity, genotoxicity, in vitro cell models, biocompatibility data and its related failure. Chapter four describes degradable biomaterial for medical implants, which include biodegradable polymers, biodegradable metals, degradation assessment techniques and future directions. Chapter five focuses on animal models for biomaterial research, ethics, care and use, implantation study and monitoring and studies on medical implants in animals in Indonesia. Chapter six covers biomimetic bioceramics, natural-based biocomposites and the latest research on natural-based biomaterials in Indonesia. Chapter seven describes recent advances in natural biomaterial from human and animal tissue, its processing and applications. Chapter eight discusses orthopedic applications of biomaterials focusing on most common problems in Indonesia, and surgical intervention and implants. Chapter nine describes biomaterials in dentistry and their development in Indonesia.

• Author : Gianfranco Donelli
• Publisher : Springer
• Release Date : 2014-11-10
• Total pages : 195
• ISBN : 9783319097824
• File Size : 21,6 Mb
• Total Download : 411
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Download Biofilm-based Healthcare-associated Infections in PDF, Epub, and Kindle

The aim of this book is to provide readers with a wide overview of the main healthcare-associated infections caused by bacteria and fungi able to grow as biofilm. The recently acquired knowledge on the pivotal role played by biofilm-growing microorganisms in healthcare-related infections has given a new dynamic to detection, prevention and treatment of these infections in patients admitted to both acute care hospitals and long-term care facilities. Clinicians, hygienists and microbiologists will be updated by leading scientists on the state-of-art of biofilm-based infections and on the most innovative strategies for prevention and treatment of these infections, often caused by emerging multidrug-resistant biofilm-growing microorganisms.

• Author : Samuel P. Sawan,Gurusamy Manivannan
• Publisher : CRC Press
• Release Date : 1999-12-10
• Total pages : 346
• ISBN : 9781482293944
• File Size : 37,6 Mb
• Total Download : 830
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Download Antimicrobial/Anti-Infective Materials in PDF, Epub, and Kindle

As our consciousness of microbes increases, it appears that our desire to control our interactions with germs also increases in proportion. This is clearly demonstrated by examining the incredible growth in the number and sales volume of consumer products with antimicrobial claims. In the medical field as well, there is much interest in the use of

• Author : Andrew William Batchelor,Margam Chandrasekaran,J R Batchelor
• Publisher : World Scientific
• Release Date : 2004-10-21
• Total pages : 260
• ISBN : 9781783260607
• File Size : 18,6 Mb
• Total Download : 117
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Download Service Characteristics Of Biomedical Materials And Implants in PDF, Epub, and Kindle

A wide variety of materials is being used in biomedical engineering for various functions. This includes a range of ceramics, polymers and metallic materials for implants and medical devices. A major question is how these materials will perform inside the body, which is very sensitive to alien materials. The material must not only survive to perform its intended function but also not initiate any damage to the surrounding tissue or induce a wider health problem. The service characteristics of implanted materials are of vital concern to health treatments that alleviate ageing.This book collates information and provides a concise text on the performance of different materials used in devices and implants. The knowledge presented is critical for a biomedical engineer, especially for the purpose of selecting the right materials. In addition, topics such as allergies and infection, tissue scaffolds, and drug delivery are reviewed.

• Author : Dustin L. Williams
• Publisher : Springer Nature
• Release Date : 2019-11-06
• Total pages : 162
• ISBN : 9783030306670
• File Size : 49,5 Mb
• Total Download : 669
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Download Targeting Biofilms in Translational Research, Device Development, and Industrial Sectors in PDF, Epub, and Kindle

This book offers a much-needed discussion on the targeting of biofilm-related infections. Chapters include discussions on the impact of biofilm on medical implants, industrial applications, as well as wound and tissue infections. It also offers discussions on regulatory management for industrial sectors and medical environments. Given that there continues to be a paucity of effective antimicrobial products, devices, and coatings in clinical and industrial use that effectively reduce rates of infection or biofilm-related problems, Targeting Biofilms in Translational Research, Device Development, and Industrial Sectors, offers a fresh and much-needed perspective aimed at helping create healthier controlled environments and safer devices. This comprehensive book is indispensable for industrial and academic translational researchers, device developers, and regulatory experts looking to create more effective antimicrobial products.

• Author : Bingyun Li,Thomas Fintan Moriarty,Thomas Webster,Malcolm Xing
• Publisher : Springer Nature
• Release Date : 2020-03-02
• Total pages : 650
• ISBN : 9783030344757
• File Size : 49,6 Mb
• Total Download : 181
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Download Racing for the Surface in PDF, Epub, and Kindle

This book covers the latest research in biofilm, infection, and antimicrobial strategies in reducing and treating musculoskeletal, skin, transfusion, implant-related infections, etc. Topics covered include biofilms, small colony variants, antimicrobial biomaterials (antibiotics, antimicrobial peptides, hydrogels, bioinspired interfaces, immunotherapeutic approaches, and more), antimicrobial coatings, engineering and 3D printing, antimicrobial delivery vehicles, and perspectives on clinical impacts. Antibiotic resistance, which shifts the race toward bacteria, and strategies to reduce antibiotic resistance, are also briefly touched on. Combined with its companion volume, Racing for the Surface: Pathogenesis of Implant Infection and Advanced Antimicrobial Strategies, this book bridges the gaps between infection and tissue engineering, and is an ideal book for academic researchers, clinicians, industrial engineers and scientists, governmental representatives in national laboratories, and advanced undergraduate students and post-doctoral fellows who are interested in infection, microbiology, and biomaterials and devices.

• Author : Kayvon Modjarrad,Sina Ebnesajjad
• Publisher : Elsevier
• Release Date : 2013-12-05
• Total pages : 368
• ISBN : 9780323221696
• File Size : 44,6 Mb
• Total Download : 680
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Download Handbook of Polymer Applications in Medicine and Medical Devices in PDF, Epub, and Kindle

While the prevalence of plastics and elastomers in medical devices is now quite well known, there is less information available covering the use of medical devices and the applications of polymers beyond medical devices, such as in hydrogels, biopolymers and silicones beyond enhancement applications, and few books in which these are combined into a single reference. This book is a comprehensive reference source, bringing together a number of key medical polymer topics in one place for a broad audience of engineers and scientists, especially those currently developing new medical devices or seeking more information about current and future applications. In addition to a broad range of applications, the book also covers clinical outcomes and complications arising from the use of the polymers in the body, giving engineers a vital insight into the real world implications of the devices they’re creating. Regulatory issues are also covered in detail. The book also presents the latest developments on the use of polymers in medicine and development of nano-scale devices. Gathers discussions of a large number of applications of polymers in medicine in one place Provides an insight into both the legal and clinical implications of device design Relevant to industry, academic and medical professionals Presents the latest developments in the field, including medical devices on a nano-scale

• Author : Tamilvanan Shunmugaperumal
• Publisher : John Wiley & Sons
• Release Date : 2010-12-28
• Total pages : 440
• ISBN : 1118043553
• File Size : 11,6 Mb
• Total Download : 836
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Download Biofilm Eradication and Prevention in PDF, Epub, and Kindle

Biofilm Eradication and Preventions presents the basics of biofilm formation on medical devices, diseases related to this formation, and approaches pharmaceutical researchers need to take to limit this problem. Split into three parts, the first deals with the development and characterization of biofilm on the surfaces of implanted or inserted medical devices. Questions as to why biofilms form over medical device surfaces and what triggers biofilm formation are addressed. In the second section, the author discusses biofilm-mediated chronic infections occurred in various organs (eyes, mouth, wounds) and pharmaceutical and drug delivery knowledge gained from research in these area. The third part explores pharmaceutical approaches like lipid-and polymer-based drug delivery carriers for eradicating biofilm on device-related infections. In addition, this section also explores the topic of novel small molecule (like iron and its complexes/metal chelators) and a quorum-sensing inhibitors to control medical biofilm formation.

• Author : Zohra Khatoon
• Publisher : Unknown
• Release Date : 2018
• Total pages : 229
• ISBN : OCLC:1107411197
• File Size : 22,8 Mb
• Total Download : 411
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Download Silver Nanocomposite Material as Antibacterial Coating on Indwelling Medical Devices-Based Biomaterials in PDF, Epub, and Kindle

The most common type of adverse events in healthcare in Canada reported by the Canadian Institute for Health Information (CIHI) are nosocomial infections. Amongst nosocomial infections, implant associated infections have been reported to be most common. Despite having the implantation surgeries carefully performed, a small, but still considerable number of devices gets colonized by bacteria resulting in implant associated infections and/or surgical site infections. The patients are then started on high dose antibiotics, which if ineffective, is followed by reimplantation surgeries that leads to long hospital stays and detrimental effects in their lives. Due to this, an alternative to antibiotics is required which could prevent and/or treat bacterial colonization on implants. The main objective of this thesis was to demonstrate the effectiveness of an antimicrobial based CLKRS peptide capped silver nanoparticle coating on a metallic and polymeric based biomaterial used in various implantable medical devices. The CLKRS peptide capped silver nanoparticle formulation was specifically engineered and tested for its antibacterial and antibiofilm properties. Silver nanoparticles were synthesised by photochemical reduction of silver ions upon photocleavage of the photoinitiator I-2959. The metal nanostructure surfaces were protected with the CLKRS peptide and tested on planktonic and biofilms of P. aeruginosa, S. aureus and S. epidermidis. The bacterial quantification was done by survival colony counting. The cytotoxicity of the silver nanoparticle formulation was also tested on human dermal fibroblast, mouse bone marrow derived macrophages, and human epithelial cells by cell proliferation assay. Results show the formation of a nanometric layer of nanosilver on the surface of the material inhibiting the growth of bacteria and eradicating pre-existing biofilms with no significant cell toxicity suggesting the prepared formulation could be a useful tool in preventing and controlling infections on implants during surgery and post implantation. This technology thus could serve as an alternative therapy for surgical site infections and/or implant associated infections.

• Author : Subhash C. Anand,J F Kennedy,M Miraftab,Subbiyan Rajendran
• Publisher : Elsevier
• Release Date : 2005-11-30
• Total pages : 520
• ISBN : 9781845694104
• File Size : 15,6 Mb
• Total Download : 322
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Download Medical Textiles and Biomaterials for Healthcare in PDF, Epub, and Kindle

Medical textiles are a major growth area within the technical textiles industry and the range of applications continues to grow and increase in diversity with every new development. Recent innovations include novel chitosan-alginate fibres for advanced wound dressings, ultrasonic energy for bleaching cotton medical textiles, durable and rechargeable biocidal textiles, spider silk supportive matrix for cartilage regeneration, barbed bi-directional surgical sutures and intelligent textiles for medical applications. Medical textiles and biomaterials for healthcare is a culmination of the worldwide research into medical textiles and biomaterials. It is divided into eight parts covering the main areas of basic biomaterials, healthcare and hygiene products, infection control and barrier materials, bandaging and pressure garments, woundcare materials, implantable and medical devices and smart technologies. Each part contains a comprehensive overview written by leading experts in the area. The overviews are then followed by a selection of the best papers from the 2003 MEDTEX Conference, hosted by the University of Bolton. It has been extensively edited to produce what is expected to be the leading reference on this subject. Discusses worldwide research into medical textiles and biomaterials Invaluable reference for this developing area of technical textiles A selection of the best papers from the 2003 MEDTEX Conference, hosted by University of Bolton are included

• Author : Steven M. Kurtz
• Publisher : Academic Press
• Release Date : 2009-04-27
• Total pages : 568
• ISBN : 008088444X
• File Size : 42,6 Mb
• Total Download : 535
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Download UHMWPE Biomaterials Handbook in PDF, Epub, and Kindle

UHMWPE Biomaterials Handbook describes the science, development, properties and application of of ultra-high molecular weight polyethylene (UHMWPE) used in artificial joints. This material is currently used in 1.4 million patients around the world every year for use in the hip, knee, upper extremities, and spine. Since the publication of the 1st edition there have been major advances in the development and clinical adoption of highly crosslinked UHMWPE for hip and knee replacement. There has also been a major international effort to introduce Vitamin E stabilized UHMWPE for patients. The accumulated knowledge on these two classes of materials are a key feature of the 2nd edition, along with an additional 19 additional chapters providing coverage of the key engineering aspects (biomechanical and materials science) and clinical/biological performance of UHMWPE, providing a more complete reference for industrial and academic materials specialists, and for surgeons and clinicians who require an understanding of the biomaterials properties of UHMWPE to work successfully on patient applications. The UHMWPE Handbook is the comprehensive reference for professionals, researchers, and clinicians working with biomaterials technologies for joint replacement New to this edition: 19 new chapters keep readers up to date with this fast moving topic, including a new section on UHMWPE biomaterials; highly crosslinked UHMWPE for hip and knee replacement; Vitamin E stabilized UHMWPE for patients; clinical performance, tribology an biologic interaction of UHMWPE State-of-the-art coverage of UHMWPE technology, orthopedic applications, biomaterial characterisation and engineering aspects from recognised leaders in the field