Athymic Nude Rat Brain Atlas

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Athymic Nude Rat Brain Atlas

Athymic Nude Rat Brain Atlas
  • Author : Bengt Mattsson,Malin Parmar,Anders Björklund
  • Publisher : Elsevier
  • Release Date : 2023-04-18
  • Total pages : 147
  • ISBN : 9780323997416
  • File Size : 46,8 Mb
  • Total Download : 711
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Athymic Nude Rat Brain Atlas will provide the first stereotaxic brain atlas of the athymic nude rat (Crl:NIH-Foxn1rnu), a T-cell deficient rat model commonly used in experimental studies and pre-clinical safety and efficacy studies. This 2D vector-based atlas contains coronal, sagittal, and horizontal brain sections of an athymic rat brain rendered from a single cleared specimen, placed in a computerized 3D environment. The maps enable readers to better calculate co-ordinates to target specific structures for toxin, virus, or cell delivery using stereotaxic surgery. This atlas will be a valuable resource for any neuroscientist who wishes to work with nude rats in experimental and pre-clinical studies. Contains coronal, sagittal, and horizontal maps of young adult athymic nude rat brain, spaced with a distance of 0.2 or 0.25 mm Uses "flat skull" Bregma and Lambda as anatomical landmarks for correct placement in the 3D environment Anatomical structures and nomenclature follow the standard set by the Paxinos and Watson rat brain atlases Includes a map of the dopamine projection system as well as the distribution of the A8-A14 dopamine cell groups Allows for easy read-out of coordinates for precise injections using stereotactic surgery

Cumulated Index Medicus

Cumulated Index Medicus
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2000
  • Total pages : 1840
  • ISBN : OSU:32436010864682
  • File Size : 18,7 Mb
  • Total Download : 514
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PDF book entitled Cumulated Index Medicus written by Anonim and published by Unknown which was released on 2000 with total hardcover pages 1840, the book become popular and critical acclaim.

ILAR News

ILAR News
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1980
  • Total pages : 229
  • ISBN : UIUC:30112005809394
  • File Size : 47,9 Mb
  • Total Download : 157
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PDF book entitled ILAR News written by Anonim and published by Unknown which was released on 1980 with total hardcover pages 229, the book become popular and critical acclaim.

Companion Guide to Infectious Diseases of Mice and Rats

Companion Guide to Infectious Diseases of Mice and Rats
  • Author : National Research Council,Commission on Life Sciences,Institute for Laboratory Animal Research,Committee on Infectious Diseases of Mice and Rats
  • Publisher : National Academies Press
  • Release Date : 1991-02-01
  • Total pages : 106
  • ISBN : 9780309042833
  • File Size : 24,5 Mb
  • Total Download : 342
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This companion to Infectious Diseases of Mice and Rats makes practical information on rodent diseases readily accessible to researchers. This volume parallels the three parts of the main volume. Part I, Principles of Rodent Disease Prevention, briefly examines the requirements for maintaining pathogen-free rodents, factors in designing health surveillance programs, and other laboratory management issues. Part II, Disease Agents, is an easy-to-use reference section, listing diagnosis and control methods, the potential for interference with research, and other factors for disease agents ranging from adenoviruses to tapeworms. It covers bacteria, viruses, fungi and common ectoparasites, and endoparasites. Part III, Diagnostic Indexes, presents alphabetical listings of clinical signs, pathology, and research complications and lists infectious agents that might be responsible for each.

Advanced Imaging in Biology and Medicine

Advanced Imaging in Biology and Medicine
  • Author : Ch.W. Sensen,Benedikt Hallgrimsson
  • Publisher : Springer Science & Business Media
  • Release Date : 2008-12-03
  • Total pages : 445
  • ISBN : 9783540689935
  • File Size : 10,8 Mb
  • Total Download : 442
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A picture says more than a thousand words. This is something that we all know to be true. Imaging has been important since the early days of medicine and bi- ogy, as seen in the anatomical studies of Leonardo Da Vinci or Andreas Vesalius. More than 100 years ago, the ?rst noninvasive imaging technologies, such as K- rad Roentgen’s X-ray technology,were applied to the medical ?eld—and while still crude—revolutionized medical diagnosis. Today, every patient will be exposed to some kind of advanced imaging technology such as medical resonance imaging, computed tomography or four-dimensional ultrasound during their lifetime. Many diseases, such as brain tumors, are initially diagnosed solely by imaging, and most of the surgical planning relies on the patient imagery. 4D ultrasound is available to expecting parents who wish to create unique early memories of the new baby, and it may soon be used for the morphometric diagnosis of malformations that may one day be treatable—inutero! Light and electron microscopy are unequal brethren, which have contributed to most of our knowledge about the existence and organization of cells, tissues and microorganisms. Every student of biology or medicine is introduced to the fascinating images of the microcosm. New advances have converted these im- ing technologies, which were considered by many to be antiquated, into powerful tools for research in systems biology and related ?elds.

The Laboratory Rat

The Laboratory Rat
  • Author : Mark A. Suckow,F. Claire Hankenson,Ronald P. Wilson,Patricia L. Foley
  • Publisher : Academic Press
  • Release Date : 2019-11-10
  • Total pages : 1180
  • ISBN : 9780128143391
  • File Size : 21,6 Mb
  • Total Download : 732
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The third edition of The Laboratory Rat features updated information on a variety of topics, including rats as research models for basic and translational research in areas such as genomics, alcoholism, diabetes, metabolic syndrome, obesity, neuroscience, spinal cord injury, traumatic brain injury, regenerative medicine, and infectious disease. New information related to the husbandry and veterinary care of rats is provided including topics related to nutrition, reproduction, anesthesia and surgery, infectious and noninfectious disease, and the care of surgical and other fragile models. It is a premier source of information on the laboratory rat, this book will be of interest to veterinary and medical students, senior graduate students, postdocs and researchers who utilize animals in biomedical research. New chapters on the care of surgical and fragile models and on the use of rats in research areas such as alcoholism, regenerative medicine, spinal cord injury, traumatic brain injury, and others are included. All chapters were written by scientific and veterinary experts. This book condenses information from many sources on topics related to the care and use of rats in research. It is the premier source of information on the laboratory rat.

Advances in Stereotactic and Functional Neurosurgery 12

Advances in Stereotactic and Functional Neurosurgery 12
  • Author : Christoph B. Ostertag,David G..T. Thomas,Andries Bosch,Bengt Linderoth,Giovanni Broggi
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Total pages : 144
  • ISBN : 9783709165133
  • File Size : 52,8 Mb
  • Total Download : 756
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Neurosurgery o/the Future: Computers and Robots in Clinical Neurosurgical Practice and in Training - a Philosophical Journey into the Future Many present day neurosurgeons believe that they already obtain good results in operative surgery with the benefit of the operating microscope and other aids which have become available in the last three decades and that the introduction of computers and robots to the operating theatre is superfluous. However, it is clear from analogy with the function of the airline pilot, another profession where there are great demands on manual skill and on spatial awareness, that these devices do have much to offer neurosurgery. Classical neurosurgery, in the time of Cushing, Dandy and Scarff, was based on a three dimensional picture of the patient's brain formed in the surgeon's mind and often illustrated in elegant drawings. Such pictures were based on neuroradiological studies by pneumoencephalography, ventriculography or by angiography. Generally these stud ies showed the presence and position of a lesion by displacement of normal brain structures and the picture was built up by interference. This was then converted by the experienced neurosurgeon into a plan for the craniotomy site and the trajectory of the surgical approach. Once the brain was exposed further pre-operative information was obtained by visual inspection and by palpation with the brain needle. These classical forms ofneuroradiology have largely been superseded by computerised tomography and by magnetic resonance imaging.

Irreversible Electroporation

Irreversible Electroporation
  • Author : Boris Rubinsky
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-11-25
  • Total pages : 313
  • ISBN : 9783642054204
  • File Size : 13,8 Mb
  • Total Download : 974
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Non-thermal irreversible electroporation is a new minimally invasive surgical p- cedure with unique molecular selectivity attributes – in fact it may be considered the first clinical molecular surgery procedure. Non-thermal irreversible electro- ration is a molecular selective mode of cell ablation that employs brief electrical fields to produce nanoscale defects in the cell membrane, which can lead to cell death, without an effect on any of the other tissue molecules. The electrical fields can be produced through contact by insertion of electrode needles around the undesirable tissue and non-invasively by electromagnetic induction. This new - dition to the medical armamentarium requires the active involvement and is of interest to clinical physicians, medical researchers, mechanical engineers, che- cal engineers, electrical engineers, instrumentation designers, medical companies and many other fields and disciplines that were never exposed in their training to irreversible electroporation or to a similar concept. This edited book is designed to be a comprehensive introduction to the field of irreversible electroporation to those that were not exposed or trained in the field before and can also serve as a reference manual. Irreversible electroporation is broad and interdisciplinary. Therefore, we have made an attempt to cover every one of the various aspects of the field from an introductory basic level to state of the art.

Carcinogenesis Abstracts

Carcinogenesis Abstracts
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1980
  • Total pages : 1004
  • ISBN : RUTGERS:43008000111718
  • File Size : 11,7 Mb
  • Total Download : 310
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PDF book entitled Carcinogenesis Abstracts written by Anonim and published by Unknown which was released on 1980 with total hardcover pages 1004, the book become popular and critical acclaim.

Index Medicus

Index Medicus
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2002
  • Total pages : 1396
  • ISBN : OSU:32436011091475
  • File Size : 55,8 Mb
  • Total Download : 787
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PDF book entitled Index Medicus written by Anonim and published by Unknown which was released on 2002 with total hardcover pages 1396, the book become popular and critical acclaim.

The Reoviridae

The Reoviridae
  • Author : Wolfgang K. Joklik
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-11-21
  • Total pages : 571
  • ISBN : 9781489905802
  • File Size : 54,7 Mb
  • Total Download : 604
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It is now just 20 years since Gomatos and his co-workers at the Rocke feller University showed that the nucleic acid in reovirus particles is double-stranded RNA (dsRNA). This discovery created great excitement, for dsRNA was at that time under intense investigation as the replicative form of viral genomes consisting of single-stranded RNA. An equally interesting and important finding followed soon after: it was found that the reovirus genome consists, not of a single nucleic acid molecule, but of 10 discrete "segments," each with its specific sequence content and each transcribed into its own messenger RNA. It is clear now that these segments are genes. Not surprisingly, the availability of a viral genome 10 unlinked genes has permitted some unique lines of in consisting of vestigation in molecular biology. Mammalian and avian reoviruses proved to be but the first of several viruses recognized as sharing Similarity in size and morphology and ge nomes consisting of 10, II, or 12 separate genes. These viruses are dis tributed throughout living organisms; among the natural hosts of mem bers of this virus family are vertebrates, Insects, and plants. Members of the Reoviridae family differ widely in the virulence that they exhibit toward their hosts . . For example, the first discovered mam malian reovirus literally is, as the name signifies, a "respiratory enteric orphan" virus, that is, a virus unassociated with disease.

Medical Subject Headings

Medical Subject Headings
  • Author : National Library of Medicine (U.S.)
  • Publisher : Unknown
  • Release Date : 1997
  • Total pages : 728
  • ISBN : UOM:39015036556986
  • File Size : 24,7 Mb
  • Total Download : 355
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PDF book entitled Medical Subject Headings written by National Library of Medicine (U.S.) and published by Unknown which was released on 1997 with total hardcover pages 728, the book become popular and critical acclaim.

Research Awards Index

Research Awards Index
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1977
  • Total pages : 229
  • ISBN : MINN:30000008789137
  • File Size : 28,5 Mb
  • Total Download : 567
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PDF book entitled Research Awards Index written by Anonim and published by Unknown which was released on 1977 with total hardcover pages 229, the book become popular and critical acclaim.

Guide for the Care and Use of Laboratory Animals

Guide for the Care and Use of Laboratory Animals
  • Author : National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Committee for the Update of the Guide for the Care and Use of Laboratory Animals
  • Publisher : National Academies Press
  • Release Date : 2011-01-27
  • Total pages : 246
  • ISBN : 9780309154000
  • File Size : 28,7 Mb
  • Total Download : 294
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A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

Bibliography of Agriculture

Bibliography of Agriculture
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1987
  • Total pages : 874
  • ISBN : STANFORD:36105014006121
  • File Size : 24,7 Mb
  • Total Download : 635
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PDF book entitled Bibliography of Agriculture written by Anonim and published by Unknown which was released on 1987 with total hardcover pages 874, the book become popular and critical acclaim.

Innate Immune Responses in CNS Inflammation

Innate Immune Responses in CNS Inflammation
  • Author : Mireia Guerau-de-Arellano,David Pitt,Astrid E. Cardona
  • Publisher : Frontiers Media SA
  • Release Date : 2021-11-30
  • Total pages : 256
  • ISBN : 9782889717422
  • File Size : 18,8 Mb
  • Total Download : 214
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PDF book entitled Innate Immune Responses in CNS Inflammation written by Mireia Guerau-de-Arellano,David Pitt,Astrid E. Cardona and published by Frontiers Media SA which was released on 2021-11-30 with total hardcover pages 256, the book become popular and critical acclaim.

Laboratory Animal Medicine

Laboratory Animal Medicine
  • Author : James G. Fox,Bennett J. Cohen,Franklin M. Loew
  • Publisher : Academic Press
  • Release Date : 2013-10-02
  • Total pages : 766
  • ISBN : 9781483269160
  • File Size : 52,6 Mb
  • Total Download : 939
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Laboratory Animal Medicine is a compilation of papers that deals with the diseases and biology of major species of animals used in medical research. The book discusses animal medicine, experimental methods and techniques, design and management of animal facilities, and legislation on laboratory animals. Several papers discuss the biology and diseases of mice, hamsters, guinea pigs, and rabbits. Another paper addresses the dog and cat as laboratory animals, including sourcing of these animals, housing, feeding, and their nutritional needs, as well as breeding and colony management. The book also describes ungulates as laboratory animals, including topics on sourcing, husbandry, preventive medical treatments, and housing facilities. One paper addresses primates as test animals, covering the biology and diseases of old world primates, Cebidae, and ferrets. Some papers pertain to the treatment, diseases, and needed facilities for birds, amphibians, and fish. Other papers then deal with techniques of experimentation, anesthesia, euthanasia, and some factors (spontaneous diseases) that complicate animal research. The text can prove helpful for scientists, clinical assistants, and researchers whose work involves laboratory animals.

Journal of the National Cancer Institute

Journal of the National Cancer Institute
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1988
  • Total pages : 560
  • ISBN : NWU:35558001566146
  • File Size : 49,5 Mb
  • Total Download : 472
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"Summaries of papers" contained in the journal accompany each issue, 19--

Mouse as a Model Organism

Mouse as a Model Organism
  • Author : Cord Brakebusch,Taina Pihlajaniemi
  • Publisher : Springer Science & Business Media
  • Release Date : 2011-03-29
  • Total pages : 176
  • ISBN : 9789400707504
  • File Size : 23,8 Mb
  • Total Download : 101
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Cell culture based research is important for our understanding of biological processes at the cellular and molecular level. Using this approach, the previous decades have produced a wealth of mechanistic information in all areas of biomedical research. Such in vitro research, however, lacks the complexity of in vivo investigations, where many different cell types interact with each other in a normal, three-dimensional environment, with normal levels of cytokines and growth factors. Furthermore, complex human diseases, such as cancer, diabetes or chronic inflammation, can only be modeled in vivo. Due to its small size, its short reproduction time, and the possibility to introduce specific gene mutations, the mouse has become the favourite mammalian model organism to study in vivo function of genes during development and in disease. This book combines review articles on selected subjects presented at the symposium “Mouse as a Model Organism – From Animals to Cells”, held in Rovaniemi, Finland, 2009. Among other topics, high-throughput phenotyping of mouse mutants, mouse phenotypes dependent on nature and nuture, and a spectrum of in vivo, ex vivo and in vitro methods to study cancer in mice are described. This book will give an excellent introduction to scientists interested in the use of mice as a model to understand complex biological questions in the post-genomic era. It will highlight the possibilities, but also discuss the current problems and shortcomings, to give a realistic view of the current state-of-art in this fascinating field of biomedical research.

Imidazole Dipeptides

Imidazole Dipeptides
  • Author : Victor R Preedy
  • Publisher : Royal Society of Chemistry
  • Release Date : 2015-08-03
  • Total pages : 602
  • ISBN : 9781782622611
  • File Size : 18,5 Mb
  • Total Download : 952
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Carnosine and anserine are two common histidine-derived dipeptides, also known as imidazole dipeptides, found in muscle and brain tissues of animals. Their dietary and nutritional significance lies in their antioxidant properties and a number of investigators are looking at other health benefits of the compounds. This volume surveys the current state of play in these and other areas of interest, including chemistry and biochemistry, immunology and cellular homeostasis. Chapters look in depth at some of the functions and effects in the body particularly with regard to exercise and fatigue, wound healing, cancer treatment and age-related diseases. Providing an up to date, interdisciplinary approach, this book is of great interest to researchers and professionals in chemistry, food science, nutrition, biochemistry, health sciences and sports sciences.

Stem Cell Biology and Regenerative Medicine

Stem Cell Biology and Regenerative Medicine
  • Author : Charles Durand,Pierre Charbord
  • Publisher : CRC Press
  • Release Date : 2022-09-01
  • Total pages : 442
  • ISBN : 9781000791648
  • File Size : 49,9 Mb
  • Total Download : 320
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The study of stem cell biology is under intensive investigation. Because stem cells have the unique capability to self-renew and differentiate into one or several cell types, they play a critical role in development, tissue homeostasis and regeneration. Stem cells also constitute promising cell candidates for cell and gene therapy. The aim of this book is to provide readers and researchers with timely and accurate knowledge on stem cell biology and regenerative medicine. This book will cover many topics in the field and is based on conferences given by recognized scientists involved in the international master course on stem cell biology at Sorbonne Université in Paris.